A portable smartphone-based laryngoscope system for high-speed vocal cord imaging of patients with throat disorders (Preprint)
BACKGROUND Recently, high-speed digital imaging (HSDI), especially HSD endoscopic imaging is being routinely used for the diagnosis of vocal fold disorders. However, high-speed digital endoscopic imaging devices are usually large and costly, which limits access by patients in underdeveloped countries and in regions with inadequate medical infrastructure. Modern smartphones have sufficient functionality to process the complex calculations that are required for processing high-resolution images and videos with a high frame rate. Recently, several attempts have been made to integrate medical endoscopes with smartphones to make them more accessible to underdeveloped countries. OBJECTIVE To develop a smartphone adaptor for endoscopes to reduce the cost of devices, and to demonstrate the possibility of high-speed vocal cord imaging using the high-speed imaging functions of a high-performance smartphone camera. METHODS A customized smartphone adaptor was designed for clinical endoscopy using selective laser melting (SLM)-based 3D printing. Existing laryngoscope was attached to the smartphone adaptor to acquire high-speed vocal cord endoscopic images. Only existing basic functions of the smartphone camera were used for HSDI of the vocal folds. For image processing, segmented glottal areas were calculated from whole HSDI frames, and characteristics such as volume, shape and longitudinal edge length were analyzed. RESULTS High-speed digital smartphone imaging with the smartphone-endoscope adaptor could achieve 940 frames per second, and was used to image the vocal folds of five volunteers. The image processing and analytics demonstrated successful calculation of relevant diagnostic variables from the acquired images. CONCLUSIONS A smartphone-based HSDI endoscope system can function as a point-of-care clinical diagnostic device. Furthermore, this system is suitable for use as an accessible diagnostic method in underdeveloped areas with inadequate medical service infrastructure.