The Spectrum of Vascularized Superficial Soft-Tissue Tumors on Sonography With a Histopathologic Correlation: Part 1, Benign Tumors

2010 ◽  
Vol 195 (2) ◽  
pp. 439-445 ◽  
Author(s):  
Wook Jin ◽  
Gou Young Kim ◽  
So Young Park ◽  
Young Soo Chun ◽  
Deok Ho Nam ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Tumors ◽  
Benign Tumors ◽  
Superficial Soft Tissue

scholarly journals Histopathological study of soft tissue tumours in a tertiary health centre in southern part of Assam

2021 ◽  
Vol 9 (11) ◽  
pp. 3391
Author(s):  
Khadija S. Tapadar ◽  
Manoj K. Deka ◽  
R. N. Chaubey ◽  
Shah A. Sheikh ◽  
Gargi R. Choudhury ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Malignant Tumors ◽  
Soft Tissue Tumors ◽  
The Body ◽  
World Health ◽  
Vascular Tumors ◽  
Benign Tumors ◽  
Peripheral Nerve Sheath Tumors ◽  
Pleomorphic Sarcoma ◽  
Younger Age

Background: Soft tissue tumors are defined as mesenchymal proliferations which occur in the extraskeletal non-epithelial tissues of the body, excluding the viscera, coverings of brain and   lymphoreticular system. The objective of this study was to study the histopathological features of soft tissue tumors and to study the occurrence of soft tissue tumors in relation to age, sex and anatomical site.Methods: This study comprised of 89 cases studied over a period of two years. All soft tissue tumors, their gross features, microscopic findings were analysed in detail. Soft tissue tumors were divided into benign and malignant categories and further sub typing were done according to World Health Organization (WHO) classification. The distribution of soft tissue tumors according to the age, sex and site of occurrence was studied.Results: Out of 89 cases of soft tissue tumors, 76 cases were benign, 4 cases belonged to intermediate category and 9 cases were malignant. Adipocytic tumors formed the largest group constituting 39 cases. Vascular tumors were the second commonest (26 cases) followed by peripheral nerve sheath tumors (11 cases). The benign tumors were seen in younger age as compared to malignant tumors. Malignant soft tissue tumors was seen to be more common in male than female and pleomorphic sarcoma and liposarcoma was commonest (3 cases each).Conclusions: Benign tumors were more common than malignant. The most common benign tumors were lipoma followed by hemangioma and schwannoma. The most common malignant tumor was pleomorphic sarcoma. The benign tumors were seen in younger age as compared to malignant tumors.

The Role of Ultrasound in the Diagnosis of Soft Tissue Tumors

2020 ◽  
Vol 24 (02) ◽  
pp. 135-155
Author(s):  
Maria Pilar Aparisi Gómez ◽  
Costantino Errani ◽  
Radhesh Lalam ◽  
Violeta Vasilevska Nikodinovska ◽  
Stefano Fanti ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Benign Lesion ◽  
Soft Tissue Tumors ◽  
Resonance Imaging ◽  
Benign Lesions ◽  
Tumor Center ◽  
Soft Tissue Masses ◽  
Magnetic Resonance Imaging Mri ◽  
Superficial Soft Tissue

AbstractThe vast majority of soft tissue masses are benign. Benign lesions such as superficial lipomas and ganglia are by far the most common soft tissue masses and can be readily identified and excluded on ultrasound (US). US is an ideal triaging tool for superficial soft tissue masses. Compared with magnetic resonance imaging (MRI), High-resolution US is inexpensive, readily available, well tolerated, and safe. It also allows the radiologist to interact with the patient as a clinician. In this review, we describe and illustrate the lesions with typical (diagnostic) US features. When the appearances of the lesion are not typical as expected for a benign lesion, lesions are deep or large, or malignancy is suspected clinically, MRI and biopsy are needed. The management of suspicious soft tissue tumors has to be carefully planned by a multidisciplinary team involving specialized surgeons and pathologists at a tumor center.

Accuracy of ultrasound in the characterization of superficial soft tissue tumors: a prospective study

2020 ◽  
Vol 49 (6) ◽  
pp. 883-892 ◽  
Author(s):  
Esther H. Y. Hung ◽  
James F. Griffith ◽  
Stefanie W. Y. Yip ◽  
Marina Ivory ◽  
Jeremiah C. H. Lee ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Prospective Study ◽  
Soft Tissue Tumors ◽  
A Prospective Study ◽  
Superficial Soft Tissue

scholarly journals High-resolution Ultrasonography in Superficial Soft Tissue Tumors

2007 ◽  
Vol 15 (3) ◽  
pp. 152-174 ◽  
Author(s):  
Hong-Jen Chiou ◽  
Yi-Hong Chou ◽  
See-Ying Chiou ◽  
Hsin-Kai Wang
Keyword(s):  
High Resolution ◽  
Soft Tissue ◽  
Soft Tissue Tumors ◽  
High Resolution Ultrasonography ◽  
Superficial Soft Tissue

Thermographic assessment of skin and soft tissue tumors in cats

2020 ◽  
pp. 1098612X2096104
Author(s):  
Andressa Gianotti Campos Nitrini ◽  
Bruno Cogliati ◽  
Julia Maria Matera
Keyword(s):  
Soft Tissue ◽  
Infrared Thermography ◽  
Normal Skin ◽  
Tumor Grade ◽  
Soft Tissue Tumors ◽  
Benign Tumors ◽  
Tumor Type ◽  
Histologic Subtype ◽  
Oncologic Patients ◽  
Neoplastic Lesions

Objectives This study set out to determine the average temperature of skin and soft tissue tumors in cats using infrared thermography and to investigate correlations between thermographic findings and tumor type. Correlations between thermographic findings, histologic subtype and tumor grade were also investigated in cases of feline injection site sarcoma (FISS). Methods Thermographic images of normal skin and skin overlying neoplastic lesions were prospectively obtained. Following thermographic assessment, tumors were resected and submitted to histopathologic and immunohistochemical analysis. Mean temperatures detected in tumoral areas were compared between different tumor types and between FISSs of different histologic subtypes and grades. Results Thermograms obtained from 11 healthy cats and 31 cats presenting with skin and soft tissue tumors (eight benign and 23 malignant tumors, including 21 FISSs) were evaluated in this study. Thermal behavior varied widely in normal skin, as well as in skin overlying neoplastic lesions. Mean temperatures were significantly higher in malignant compared with benign tumors (35.4 ± 1.8ºC and 34.5 ± 1.7ºC respectively; P = 0.01), with a temperature above 34.7ºC being associated with malignancy (sensitivity 76%, specificity 80%; P = 0.01). Temperatures detected in FISS did not differ significantly according to histologic subtype ( P = 0.91) or tumor grade ( P = 0.46), or between primary and recurring tumors ( P = 0.25). Conclusions and relevance Infrared thermography proved to be a sensitive and effective method for detection of temperature differences between malignant and benign skin and soft tissue tumors in cats. Thermographic assessment may contribute to diagnosis and prognostic estimation in feline oncologic patients.

scholarly journals Significance of Coagulation and Fibrinolysis Markers for Benign and Malignant Soft Tissue Tumors

2020 ◽  
Author(s):  
Kunihiro Asanuma ◽  
Tomoki Nakamura ◽  
Tomohito Hagi ◽  
Takayuki Okamoto ◽  
Kouji Kita ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Malignant Tumors ◽  
Characteristic Curve ◽  
Soft Tissue Tumors ◽  
Clinicopathological Parameters ◽  
Diagnostic Tools ◽  
Benign Tumors ◽  
Benign Soft Tissue Tumors ◽  
Significant Difference ◽  
Coagulation And Fibrinolysis

Abstract Background: The intimate relationship between coagulation and fibrinolysis in malignant tumors is a well-known phenomena, with the malignant phenotype enhancing coagulation and fibrinolysis. We hypothesized that soft tissue sarcoma (STS) affects the expression of coagulation and fibrinolysis markers, which could be used to distinguish STS from benign soft tissue tumors. We analyzed the correlations between plasma levels of D-dimer (DD), plasmin-α2 plasmin inhibitor complex (PIC), soluble fibrin (SF), and thrombin-antithrombin III complex (TAT) in benign soft tissue tumors and STS to elucidate whether these markers can be used to predict STS.Methods: Plasma DD, PIC, SF and TAT levels in primary soft tissue tumors (benign, 67, STS 68) were measured before biopsy or treatment. The marker levels were analyzed and compared to various clinicopathological parameters.Results: In malignancy (STS), the average DD, PIC and SF levels were significantly higher than in benign tumors. Multivariate logistic analysis of continuous variables indicated that only PIC exhibited a significant difference (OR: 24.5, 95%CI: 3.55-170, p=0.0012). Receiver operating characteristic curve analysis produced area under the curve values for DD: 0.691, PIC: 0.784, SF: 0.734 and TAT: 0.588. Youden’s index was used to establish thresholds of 0.37 (DD), 0.80 (PIC), 0.90 (SF) and 0.82 (TAT). Threshold values for PIC and SF indicated high specificity (0.881, 0.791) and high positive predictive value (0.818, 0.745), respectively The highest accuracy value among the markers was observed for PIC (0.704). Significant differences in multivariate analysis of binary variables were demonstrated by categorizing low and high groups based on their threshold, PIC (≥0.80) (OR: 3.36, 95%CI: 1.19-9.43, p=0.0212) and SF (≥0.90) (OR: 2.63, 95%CI: 1.04-6.66, p=0.0404) . Conclusions: Of the coagulation and fibrinolysis markers studied, increased PIC levels were related to STS and over 0.80 PIC was the most suitable for the prediction of STS, which, along with other diagnostic tools, represents a helpful subsidiary tool for the prediction of STS.

scholarly journals Statistically Based Survival Rate Estimation in Patients with Soft Tissue Tumors

2018 ◽  
Vol 1 (Supplement) ◽  
pp. 7
Author(s):  
B. Şerban ◽  
Z. Panti ◽  
M. Nica ◽  
M. Pleniceanu ◽  
M. Popa ◽  
...  
Keyword(s):  
Survival Rate ◽  
Soft Tissue ◽  
Healing Rate ◽  
Malignant Tumors ◽  
Surgical Excision ◽  
Soft Tissue Tumors ◽  
Benign Tumors ◽  
Rate Estimation ◽  
Differentiation Degree ◽  
Histopathological Type

Abstract Introduction. Although most soft tissue tumors are benign, with a high healing rate after surgical excision, there is a variety of malignant tumors with differences in progression and prognosis. The study aims to assess the survival rate in patients diagnosed with this pathology, based on the patient’s characteristics (age, gender, race), as well as the tumor’s (histological type, differentiation degree, location and size). Materials and methods. The retrospective study included a group of 103 patients diagnosed in our department during 2010 and 2017. Considering the high healing rate of benign tumors, only the group of neoplastic patients (45 cases) was involved in the survival rate estimation, assessing tumor characteristics and individual comorbidities. Within this lot, we emphasized a predominance of neoplasm in patients aged over 50 years (32 cases), men (29 cases), and localization of the neoplasm in the thigh (23 cases). The predominant histopathological type, liposarcoma, was diagnosed in 67% of the cases, with dimensions over 6 cm and with local extension. Results. There have been significant variations in mortality between the different histological subtypes (liposarcoma vs. synovial sarcoma). Local recurrences were shown in 18 cases of liposarcoma in the first 2 years after the surgical excision, with an increased aggressiveness of this neoplasm in men over 50 years. 12 cases developed distant metastasis, and, until the end of the study, 7 deaths were reported in 3 cases involving associated comorbidities. Conclusions. The five-year survival is inversely proportional to the extent of the tumor and the local invasion, as well as to the age of the patient. It is difficult to appreciate an overall survival rate in the context of a heterogeneous group of tumors so it must be evaluated for every histological subtype taking into account the patient’s particularities.

scholarly journals Statistically based survival rate estimation in patients with soft tissue tumors

2018 ◽  
Vol 1 (2) ◽  
pp. 84-89
Author(s):  
Bogdan Serban ◽  
Zsombor Panti ◽  
Mihai Nica ◽  
Marian Pleniceanu ◽  
Mihnea Popa ◽  
...  
Keyword(s):  
Survival Rate ◽  
Soft Tissue ◽  
Healing Rate ◽  
Malignant Tumors ◽  
Surgical Excision ◽  
Soft Tissue Tumors ◽  
Benign Tumors ◽  
Rate Estimation ◽  
Differentiation Degree ◽  
Histopathological Type

Abstract Although most soft tissue tumors are benign, with a high healing rate after surgical excision, there is a variety of malignant tumors with differences in progression and prognosis. The study aimed to assess the survival rate in patients diagnosed with this pathology, based on the patient’s characteristics (age, gender, race), as well as the tumor’s histological type, differentiation degree, location and size. The retrospective study included a group of 103 patients diagnosed during 2010 and 2017 in our department. Considering the high healing rate of benign tumors, only the group of neoplastic patients (45 cases) was involved in the survival rate estimation, assessing tumor characteristics and individual comorbidities. Within this lot, we emphasized a predominance of neoplasm in patients aged over 50 years (32 cases), men (29 cases), and localization of the neoplasm in the thigh (23 cases). The predominant histopathological type, liposarcoma, was diagnosed in 67% of the cases, with dimensions over 6 cm and with local extension. There have been significant variations in mortality between the different histological subtypes (liposarcoma vs. synovial sarcoma). Local recurrences were showed in 18 cases of liposarcoma in the first 2 years after the surgical excision, with an increased aggressiveness of this neoplasm in men over 50 years. 12 cases developed distant metastasis, and until the end of the study, 7 deaths were reported in 3 cases involving associated comorbidities. The five-year survival is inversely proportional to the extent of the tumor and the local invasion, as well as to the age of the patient. An overall survival rate is difficult to appreciate in the context of a heterogeneous group of tumors so it must be evaluated for every histological subtype taking into account the patient’s particularities.

Sign in / Sign up

Export Citation Format

Share Document