Thermographic assessment of skin and soft tissue tumors in cats

2020 ◽  
pp. 1098612X2096104
Author(s):  
Andressa Gianotti Campos Nitrini ◽  
Bruno Cogliati ◽  
Julia Maria Matera
Keyword(s):  
Soft Tissue ◽  
Infrared Thermography ◽  
Normal Skin ◽  
Tumor Grade ◽  
Soft Tissue Tumors ◽  
Benign Tumors ◽  
Tumor Type ◽  
Histologic Subtype ◽  
Oncologic Patients ◽  
Neoplastic Lesions

Objectives This study set out to determine the average temperature of skin and soft tissue tumors in cats using infrared thermography and to investigate correlations between thermographic findings and tumor type. Correlations between thermographic findings, histologic subtype and tumor grade were also investigated in cases of feline injection site sarcoma (FISS). Methods Thermographic images of normal skin and skin overlying neoplastic lesions were prospectively obtained. Following thermographic assessment, tumors were resected and submitted to histopathologic and immunohistochemical analysis. Mean temperatures detected in tumoral areas were compared between different tumor types and between FISSs of different histologic subtypes and grades. Results Thermograms obtained from 11 healthy cats and 31 cats presenting with skin and soft tissue tumors (eight benign and 23 malignant tumors, including 21 FISSs) were evaluated in this study. Thermal behavior varied widely in normal skin, as well as in skin overlying neoplastic lesions. Mean temperatures were significantly higher in malignant compared with benign tumors (35.4 ± 1.8ºC and 34.5 ± 1.7ºC respectively; P = 0.01), with a temperature above 34.7ºC being associated with malignancy (sensitivity 76%, specificity 80%; P = 0.01). Temperatures detected in FISS did not differ significantly according to histologic subtype ( P = 0.91) or tumor grade ( P = 0.46), or between primary and recurring tumors ( P = 0.25). Conclusions and relevance Infrared thermography proved to be a sensitive and effective method for detection of temperature differences between malignant and benign skin and soft tissue tumors in cats. Thermographic assessment may contribute to diagnosis and prognostic estimation in feline oncologic patients.

scholarly journals Ultrasound Ablation: New Possibilities for Treatment of Bone and Soft-Tissue Tumors

2010 ◽  
Vol 17 (2) ◽  
pp. 41-49
Author(s):  
G I Nazarenko ◽  
V Sh Chen ◽  
A N Khitrova
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Tumor ◽  
Secondary Infection ◽  
Local Treatment ◽  
Soft Tissue Tumors ◽  
Treatment Technique ◽  
Tumor Type ◽  
Coagulative Necrosis ◽  
Ultrasound Ablation ◽  
Physical Principles

Focused high intensity ultrasound (HIFU) with sighting influence on tumor enabled to cause its complete coagulative necrosis without damage to intact environmental tissues. The possibilities of ultrasound ablation as the method of local treatment of bone and soft-tissue tumor were considered. Physical principles of method, criteria for patient selection, treatment technique as well as clinical outcomes and their evaluation were presented. Advantages of method are non-invasiveness, less traumatization, less technical complexity and dependence on surgeon skill compared with other sparing operations and methods of ablation. When necessary HIFU may be repeated several times. Effect of HIFU is independent on tumor type. Possible complications (secondary infection in coagulative necrosis zone, peripheral nerves damage, pathological fractures) and measures of their prevention are presented.

scholarly journals Histopathological study of soft tissue tumours in a tertiary health centre in southern part of Assam

2021 ◽  
Vol 9 (11) ◽  
pp. 3391
Author(s):  
Khadija S. Tapadar ◽  
Manoj K. Deka ◽  
R. N. Chaubey ◽  
Shah A. Sheikh ◽  
Gargi R. Choudhury ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Malignant Tumors ◽  
Soft Tissue Tumors ◽  
The Body ◽  
World Health ◽  
Vascular Tumors ◽  
Benign Tumors ◽  
Peripheral Nerve Sheath Tumors ◽  
Pleomorphic Sarcoma ◽  
Younger Age

Background: Soft tissue tumors are defined as mesenchymal proliferations which occur in the extraskeletal non-epithelial tissues of the body, excluding the viscera, coverings of brain and   lymphoreticular system. The objective of this study was to study the histopathological features of soft tissue tumors and to study the occurrence of soft tissue tumors in relation to age, sex and anatomical site.Methods: This study comprised of 89 cases studied over a period of two years. All soft tissue tumors, their gross features, microscopic findings were analysed in detail. Soft tissue tumors were divided into benign and malignant categories and further sub typing were done according to World Health Organization (WHO) classification. The distribution of soft tissue tumors according to the age, sex and site of occurrence was studied.Results: Out of 89 cases of soft tissue tumors, 76 cases were benign, 4 cases belonged to intermediate category and 9 cases were malignant. Adipocytic tumors formed the largest group constituting 39 cases. Vascular tumors were the second commonest (26 cases) followed by peripheral nerve sheath tumors (11 cases). The benign tumors were seen in younger age as compared to malignant tumors. Malignant soft tissue tumors was seen to be more common in male than female and pleomorphic sarcoma and liposarcoma was commonest (3 cases each).Conclusions: Benign tumors were more common than malignant. The most common benign tumors were lipoma followed by hemangioma and schwannoma. The most common malignant tumor was pleomorphic sarcoma. The benign tumors were seen in younger age as compared to malignant tumors.

The Spectrum of Vascularized Superficial Soft-Tissue Tumors on Sonography With a Histopathologic Correlation: Part 1, Benign Tumors

2010 ◽  
Vol 195 (2) ◽  
pp. 439-445 ◽  
Author(s):  
Wook Jin ◽  
Gou Young Kim ◽  
So Young Park ◽  
Young Soo Chun ◽  
Deok Ho Nam ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Tumors ◽  
Benign Tumors ◽  
Superficial Soft Tissue

Imaging of Pediatric Soft Tissue Tumors and Tumor-like Conditions

2021 ◽  
Vol 25 (01) ◽  
pp. 039-056
Author(s):  
Sinan Al-Qassab ◽  
Radhesh Lalam ◽  
Rajesh Botchu ◽  
Alberto Bazzocchi
Keyword(s):  
Soft Tissue ◽  
Clinical Presentation ◽  
Soft Tissue Tumors ◽  
Practical Approach ◽  
Differential Diagnoses ◽  
Imaging Feature ◽  
Anatomical Location ◽  
Imaging Features ◽  
Neoplastic Lesions ◽  
Malignant Lesions

AbstractLumps and bumps are frequently seen in children, and the vast majority are a result of trauma, infection, or inflammation. True soft tissue neoplastic lesions are rare; however, their wide and complex classifications make these lesions challenging to manage. Imaging features are usually nonspecific, and a reasonable list of differential diagnoses can be generated following consideration of the clinical presentation, age, and anatomical location of the lesion. In this article, we offer a practical approach to diagnosing such lesions by discussing the most common three benign and malignant lesions in different anatomical regions stratified by age with emphasis on certain features that might aid in the diagnosis such as depth, multiplicity, calcification, or other specific imaging feature.

scholarly journals Significance of Coagulation and Fibrinolysis Markers for Benign and Malignant Soft Tissue Tumors

2020 ◽  
Author(s):  
Kunihiro Asanuma ◽  
Tomoki Nakamura ◽  
Tomohito Hagi ◽  
Takayuki Okamoto ◽  
Kouji Kita ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Malignant Tumors ◽  
Characteristic Curve ◽  
Soft Tissue Tumors ◽  
Clinicopathological Parameters ◽  
Diagnostic Tools ◽  
Benign Tumors ◽  
Benign Soft Tissue Tumors ◽  
Significant Difference ◽  
Coagulation And Fibrinolysis

Abstract Background: The intimate relationship between coagulation and fibrinolysis in malignant tumors is a well-known phenomena, with the malignant phenotype enhancing coagulation and fibrinolysis. We hypothesized that soft tissue sarcoma (STS) affects the expression of coagulation and fibrinolysis markers, which could be used to distinguish STS from benign soft tissue tumors. We analyzed the correlations between plasma levels of D-dimer (DD), plasmin-α2 plasmin inhibitor complex (PIC), soluble fibrin (SF), and thrombin-antithrombin III complex (TAT) in benign soft tissue tumors and STS to elucidate whether these markers can be used to predict STS.Methods: Plasma DD, PIC, SF and TAT levels in primary soft tissue tumors (benign, 67, STS 68) were measured before biopsy or treatment. The marker levels were analyzed and compared to various clinicopathological parameters.Results: In malignancy (STS), the average DD, PIC and SF levels were significantly higher than in benign tumors. Multivariate logistic analysis of continuous variables indicated that only PIC exhibited a significant difference (OR: 24.5, 95%CI: 3.55-170, p=0.0012). Receiver operating characteristic curve analysis produced area under the curve values for DD: 0.691, PIC: 0.784, SF: 0.734 and TAT: 0.588. Youden’s index was used to establish thresholds of 0.37 (DD), 0.80 (PIC), 0.90 (SF) and 0.82 (TAT). Threshold values for PIC and SF indicated high specificity (0.881, 0.791) and high positive predictive value (0.818, 0.745), respectively The highest accuracy value among the markers was observed for PIC (0.704). Significant differences in multivariate analysis of binary variables were demonstrated by categorizing low and high groups based on their threshold, PIC (≥0.80) (OR: 3.36, 95%CI: 1.19-9.43, p=0.0212) and SF (≥0.90) (OR: 2.63, 95%CI: 1.04-6.66, p=0.0404) . Conclusions: Of the coagulation and fibrinolysis markers studied, increased PIC levels were related to STS and over 0.80 PIC was the most suitable for the prediction of STS, which, along with other diagnostic tools, represents a helpful subsidiary tool for the prediction of STS.

scholarly journals Statistically Based Survival Rate Estimation in Patients with Soft Tissue Tumors

2018 ◽  
Vol 1 (Supplement) ◽  
pp. 7
Author(s):  
B. Şerban ◽  
Z. Panti ◽  
M. Nica ◽  
M. Pleniceanu ◽  
M. Popa ◽  
...  
Keyword(s):  
Survival Rate ◽  
Soft Tissue ◽  
Healing Rate ◽  
Malignant Tumors ◽  
Surgical Excision ◽  
Soft Tissue Tumors ◽  
Benign Tumors ◽  
Rate Estimation ◽  
Differentiation Degree ◽  
Histopathological Type

Abstract Introduction. Although most soft tissue tumors are benign, with a high healing rate after surgical excision, there is a variety of malignant tumors with differences in progression and prognosis. The study aims to assess the survival rate in patients diagnosed with this pathology, based on the patient’s characteristics (age, gender, race), as well as the tumor’s (histological type, differentiation degree, location and size). Materials and methods. The retrospective study included a group of 103 patients diagnosed in our department during 2010 and 2017. Considering the high healing rate of benign tumors, only the group of neoplastic patients (45 cases) was involved in the survival rate estimation, assessing tumor characteristics and individual comorbidities. Within this lot, we emphasized a predominance of neoplasm in patients aged over 50 years (32 cases), men (29 cases), and localization of the neoplasm in the thigh (23 cases). The predominant histopathological type, liposarcoma, was diagnosed in 67% of the cases, with dimensions over 6 cm and with local extension. Results. There have been significant variations in mortality between the different histological subtypes (liposarcoma vs. synovial sarcoma). Local recurrences were shown in 18 cases of liposarcoma in the first 2 years after the surgical excision, with an increased aggressiveness of this neoplasm in men over 50 years. 12 cases developed distant metastasis, and, until the end of the study, 7 deaths were reported in 3 cases involving associated comorbidities. Conclusions. The five-year survival is inversely proportional to the extent of the tumor and the local invasion, as well as to the age of the patient. It is difficult to appreciate an overall survival rate in the context of a heterogeneous group of tumors so it must be evaluated for every histological subtype taking into account the patient’s particularities.

scholarly journals Statistically based survival rate estimation in patients with soft tissue tumors

2018 ◽  
Vol 1 (2) ◽  
pp. 84-89
Author(s):  
Bogdan Serban ◽  
Zsombor Panti ◽  
Mihai Nica ◽  
Marian Pleniceanu ◽  
Mihnea Popa ◽  
...  
Keyword(s):  
Survival Rate ◽  
Soft Tissue ◽  
Healing Rate ◽  
Malignant Tumors ◽  
Surgical Excision ◽  
Soft Tissue Tumors ◽  
Benign Tumors ◽  
Rate Estimation ◽  
Differentiation Degree ◽  
Histopathological Type

Abstract Although most soft tissue tumors are benign, with a high healing rate after surgical excision, there is a variety of malignant tumors with differences in progression and prognosis. The study aimed to assess the survival rate in patients diagnosed with this pathology, based on the patient’s characteristics (age, gender, race), as well as the tumor’s histological type, differentiation degree, location and size. The retrospective study included a group of 103 patients diagnosed during 2010 and 2017 in our department. Considering the high healing rate of benign tumors, only the group of neoplastic patients (45 cases) was involved in the survival rate estimation, assessing tumor characteristics and individual comorbidities. Within this lot, we emphasized a predominance of neoplasm in patients aged over 50 years (32 cases), men (29 cases), and localization of the neoplasm in the thigh (23 cases). The predominant histopathological type, liposarcoma, was diagnosed in 67% of the cases, with dimensions over 6 cm and with local extension. There have been significant variations in mortality between the different histological subtypes (liposarcoma vs. synovial sarcoma). Local recurrences were showed in 18 cases of liposarcoma in the first 2 years after the surgical excision, with an increased aggressiveness of this neoplasm in men over 50 years. 12 cases developed distant metastasis, and until the end of the study, 7 deaths were reported in 3 cases involving associated comorbidities. The five-year survival is inversely proportional to the extent of the tumor and the local invasion, as well as to the age of the patient. An overall survival rate is difficult to appreciate in the context of a heterogeneous group of tumors so it must be evaluated for every histological subtype taking into account the patient’s particularities.

scholarly journals Soft Tissue Tumors: Benign Tumors of Adipose Tissue

1969 ◽  
Vol 19 (1) ◽  
pp. 2-7 ◽  
Author(s):  
R. D. Brasfield ◽  
T. K. D. Gupta
Keyword(s):  
Adipose Tissue ◽  
Soft Tissue ◽  
Soft Tissue Tumors ◽  
Benign Tumors

scholarly journals Spectrum of bone and soft tissue tumors in a tertiary cancer institute in Eastern india

2018 ◽  
Vol 6 (8) ◽  
pp. 2686
Author(s):  
Ashwini Natekar ◽  
Shubasis Basu ◽  
Gavruv Gupta ◽  
Maruti Pujari
Keyword(s):  
Soft Tissue ◽  
Malignant Tumors ◽  
Soft Tissue Tumors ◽  
Benign Tumors ◽  
Age Group ◽  
Eastern India ◽  
Female Ratio ◽  
True Incidence ◽  
Site Distribution ◽  
Male Female Ratio

Background: Bone and soft tissue tumours are uncommon tumours that can affect any age group. Soft tissue tumors are said to be heterogeneous group of mesenchymal malignancies. Primary bone sarcomas are rare tumors, comprising approximately 0.2% of all cancers. Their true incidence is difficult to estimate because of their rarity. The outcome of the disease depends on the age and time at diagnosis.Methods: A study was carried out in department of pathology in tertiary cancer institute in East India from December 2015 to September 2017. A total of 60 cases were included in the study. All age group patients with indoor admissions and review cases were included in this study. Only soft tissue and bone tumors were included in the study. Epithelial tumors metastasis to bone were excluded from our study. Clinical and radiological details of patients were noted along with gross specimen findings and microscopic examination of H and E stained slides. IHC was also carried out for confirmatory diagnosis. Aims and objectives was to study the histological spectrum of bone and soft tissue tumors in a tertiary cancer institute in Eastern India. Also, to study gender distribution and site distribution of bone and soft tissue tumors.Results: Out of the total 60 cases studied 24 cases were of bone and cartilaginous tumours and 36 cases included were of soft tissue tumors. Benign tumors comprised of 08 cases (13.3%) and malignant tumors accounted to 52 cases (86.7%). Age of the patients ranged from 10 to 80 years. Male female ratio was 1.4:1.Conclusions: Multimodal therapies of treatment are practiced for bone and soft tissue tumors. Early detection and treatment is essential for diagnosis of these malignant tumors. Molecular studies are most important in diagnosing, classifying and also prognosticating bone and soft tissue tumors.

scholarly journals Tumors and pseudotumors of the soft tissues: Imaging semiology and strategy

2021 ◽  
Vol 11 ◽  
pp. 13
Author(s):  
Charlinne Paixao ◽  
Jean-Philippe Lustig ◽  
Sylvain Causeret ◽  
Loic Chaigneau ◽  
Alexis Danner ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Soft Tissues ◽  
Soft Tissue Mass ◽  
Soft Tissue Tumors ◽  
Benign Tumors ◽  
Imaging Features ◽  
Tissue Mass ◽  
Primary Tumors ◽  
Adipocytic Tumors ◽  
Diagnostic Certainty

The aims of this educational review are to learn the semiological basis of soft-tissue lesions and, with the help of diagnostic algorithms, to apply the current recommendations for the management of soft-tissue tumors. Pseudotumors must first be identified and excluded. Among primary tumors, the search for macroscopic fat content on MRI is decisive; since it restricts the diagnostic range to adipocytic tumors. Key imaging features of non-adipocytic tumors are highlighted. When a deep soft-tissue mass is found, therapeutic abstention or simple monitoring is only appropriate when there is diagnostic certainty: This is only the case for typical pseudotumors, typical benign tumors, and fat tumors without atypical criteria. In all other cases, histological evidence is required. If there is any suspicion of soft-tissue sarcoma or any undetermined lesion, the patient should be referred to a sarcoma referral center before biopsy.

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