scholarly journals Gambaran Kualitas Hidup Penderita Tuberkulosis Resistan Obat dan Karakteristiknya di Kabupaten Banyumas, Provinsi Jawa Tengah, Periode Tahun

2018 ◽  
Vol 34 (2) ◽  
pp. 55
Author(s):  
Imam Abrori ◽  
Riris Andono Ahmad
Keyword(s):  
Quality Of Life ◽  
Social Support ◽  
Low Income ◽  
Basic Education ◽  
Skills Training ◽  
Drug Resistant ◽  
Drug Resistant Tuberculosis ◽  
Resistant Tuberculosis ◽  
Multi Drug Resistant Tuberculosis

Quality of life among patients with multi-drug resistant tuberculosis in the district of BanyumasPurposeThis study was conducted to investigate the quality of life among patients with multi-drug resistant tuberculosis and to examine factors associated with them. MethodsData from an in-depth interview, involved 22 patients with multi-drug resistant tuberculosis, were used in this study. ResultsThis study showed 54.5% males, 50.0% adults, 59.1% married, 22.7% divorced, 72.7% lived in rural, 95.5% had basic education, 45.5% as a private employment (before sick), 77.3% as unemployment (after sick), 72.7% low income, 54.5% in continuation phase, 95.5%  re-treatment (45% relapse and 40.9% failure cases), 90.9% had drugs side effects (mild/severe); 36.4% had comorbidity; 45.5% smokers, 31.8% falcoholics; 54.5% lack of social support; 31.8% poor and 36.4% moderate quality of life. ConclusionPatients with multi-drug resistant tuberculosis had a worse quality of life and lack social support. Health worker needs to improve their quality of life and social support through establishing a peer support groups to give counseling, information education, communication, motivation, and skills training for them.

scholarly journals The Psychosocial Impact of Hearing Loss on the Quality of life in Adults with Multi-Drug Resistant Tuberculosis (Preprint)

2019 ◽  
Author(s):  
Amanda Thusi ◽  
Jessica Paken
Keyword(s):  
Quality Of Life ◽  
Health Care ◽  
Hearing Loss ◽  
Well Being ◽  
Drug Resistant ◽  
Drug Resistant Tuberculosis ◽  
Resistant Tuberculosis ◽  
Multi Drug Resistant Tuberculosis ◽  
Mdr Tb

BACKGROUND Aminoglycoside treatment used for MDR-TB is likely to result in ototoxicity. The effects of a hearing loss with a MDR-TB diagnosis are likely to have an increased impact on the overall quality of life of an individual. However, there is minimal research in the area, which would therefore indicate a possible lack of awareness to the effect of aminoglycoside treatment on the quality of life of patients. While most studies on drug resistant TB are focused on the public health concerns of the disease, the human costs of MDR-TB are sometimes overlooked. OBJECTIVE This study aims to describe the psychological, social, economic and vocational impact of hearing loss on the quality of life of adults with Multi-Drug Resistant Tuberculosis. METHODS A Qualitative Phenomenological research study will be conducted on 10 participants. All participants will have a laboratory confirmed diagnosis of Multi-Drug Resistant Tuberculosis. A semi-structured interview questionnaire will be used to collect data. Face-to-face interviews will be conducted and the participants will be audio recorded. All interviews will be conducted by the researcher. RESULTS The study has not concluded. CONCLUSIONS The quality of life of a patient needs to be considered in the health care system during treatment, as this data may drive improved national health care planning with regards to treatment of patients diagnosed with MDR-TB. Therefore, for a comprehensive assessment of patient’s health status, it is very much essential to assess the overall impact of MDR-TB on health and patient’s perception of well-being. Besides routine clinical and bacteriological assessments, this assessment can be done by assessing quality of life which has several domains. Patients diagnosed with MDR-TB who further acquire an aminoglycoside induced hearing loss may have life-long effects on their quality of life even after completion of treatment.

scholarly journals Neuropsychiatric reactions induced by cycloserine in the treatment of multidrug-resistant tuberculosis: what an Indian female patient tells us

2019 ◽  
Vol 12 (12) ◽  
pp. e230993 ◽  
Author(s):  
Enrica Intini ◽  
Girija Kishore ◽  
Luca Richeldi ◽  
Zarir F Udwadia
Keyword(s):  
Adverse Events ◽  
Multidrug Resistant ◽  
Drug Resistant ◽  
Drug Resistant Tuberculosis ◽  
Health Crisis ◽  
Resistant Tuberculosis ◽  
Multidrug Resistant Tuberculosis ◽  
Multi Drug Resistant Tuberculosis ◽  
Group B

Multidrug-resistant tuberculosis continues to be a public health crisis. Urgent action is required to improve the coverage and quality of diagnosis, treatment and care for people affected by drug-resistant tuberculosis. To implement tuberculosis control, in 2018, WHO recommended cycloserine as one of the Group B drugs. Following this recommendation, cycloserine should be generally included in the starting line-up in the longer regimen for the treatment of multidrug-resistant tuberculosis. However, neurological toxicity associated with this drug concerns clinicians and limits its use. In this paper, we present a case of a 48-year-old woman with a diagnosis of multidrug-resistant tuberculosis treated with cycloserine, who developed psychiatric adverse events after 3 months of administration. This case shows the need for close psychiatric follow-up to promptly detect adverse events in patients receiving regimens for multi-drug resistant tuberculosis.

scholarly journals Impacts of social support on the treatment outcomes of drug-resistant tuberculosis: a systematic review and meta-analysis

BMJ Open ◽  
2020 ◽  
Vol 10 (10) ◽  
pp. e036985
Author(s):  
Shuqin Wen ◽  
Jia Yin ◽  
Qiang Sun
Keyword(s):  
Social Support ◽  
Treatment Outcomes ◽  
Low Income ◽  
Meta Analysis ◽  
Treatment Success ◽  
Drug Resistant ◽  
Drug Resistant Tuberculosis ◽  
Middle Income ◽  
Material Support ◽  
Resistant Tuberculosis

ObjectiveTo assess the effectiveness of social support on treatment success promotion or lost to follow-up (LTFU) reduction for patients with drug-resistant tuberculosis (DR-TB).DesignWe searched Pubmed, Web of Science, Embase, Scopus and Medline databases until 18 June 2020 for interventional or mixed-method studies which reported social support and treatment outcomes of DR-TB patients. Two independent reviewers extracted data and disagreements were resolved by consensus with a third reviewer. Random-effects meta-analysis was performed to calculate the OR and 95% CI for the effects of social support on the improvement of treatment outcomes and the heterogeneity and risk of bias were assessed.SettingLow-income and middle-income countries.ParticipantsDR-TB patients.OutcomesTreatment success is defined as the combination of the cured and treatment completion, and LTFU is measured as treatment being interrupted for two consecutive months or more.ResultsAmong 173 articles selected for full-text review, 162 were excluded through independent review (kappa=0.87) and 10 studies enrolling 1621 DR-TB patients in eight countries were included for qualitative analysis. In these studies, the most frequently introduced social support was material support (10 studies), followed by informational (eight studies), emotional (seven studies) and companionship support (four studies). Seven studies that reported treatment outcomes in both intervention arm and control arm are qualified for meta-analysis. An encouraging improvement on treatment success rate (OR: 2.58; 95% CI: 1.80 to 3.69) was found when material support was integrated into social support packages and no heterogeneity was observed (I1 of 0%, Q test p=0.72). Reduction on LTFU rate (OR: 0.17; 95% CI: 0.05 to 0.55) was also noted when material support was available but substantial heterogeneity was found (I2 of 80%, Q test p=0.002).ConclusionMaterial support appeared feasible and effective to improve treatment success for DR-TB patients combined with other social support interventions.PROSPERO registration numberCRD42019140824.

Exploring patient-provider factors for risk of developing Multi-drug Resistance Tuberculosis in Southern Ethiopia: Qualitative Operation Research (Preprint)

2019 ◽  
Author(s):  
Yitagesu Habtu ◽  
Tesema Bereku ◽  
Girma Alemu ◽  
Ermias Abera
Keyword(s):  
Phenomenological Study ◽  
Treatment Success ◽  
World Health ◽  
Multi Drug Resistance ◽  
Southern Ethiopia ◽  
Drug Resistant ◽  
Related Factors ◽  
Drug Resistant Tuberculosis ◽  
Resistant Tuberculosis ◽  
Multi Drug Resistant Tuberculosis

BACKGROUND Ethiopia is one of among thirty high burden countries of multi-drug resistant tuberculosis (MDR-TB) in the regions of world health organization. Contextual evidence on the emergence of the disease is limited at a program level. OBJECTIVE The aim of the study is to explore patient-provider factors that may facilitate the emergence of multi-drug resistant tuberculosis. METHODS We used a phenomenological study design of qualitative approach from June to July, 2015. We conducted ten in-depth interviews and 4 focus group discussions with purposely selected patients and providers. We designed and used an interview guide to collect data. Verbatim transcribes were exported to open code 3.4 for emerging thematic analysis. Domain summaries were used to support core interpretation. RESULTS The study explored patient-provider factors facilitating the emergence of multi-drug resistant tuberculosis. These factors as underlying, health system and patient-related factors. Especially, the a shows conflicting finding between having a history of discontinuing drug-susceptible tuberculosis and emergence of multi-drug resistant tuberculosis. CONCLUSIONS The patient-provider factors may result in poor early case identification, adherence to and treatment success in drug sensitive or multi-drug resistant tuberculosis. Our study implies the need for awareness creation about multi-drug resistant tuberculosis for patients and further familiarization for providers. This study also shows that patients developed multi-drug resistant tuberculosis though they had never discontinued their drug-susceptible tuberculosis treatment. Therefore, further studies may require for this discording finding.

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