scholarly journals Phylogeny and Origin of Glucose-6-Phosphate Dehydrogenase (G6PD) Defi ciency Mutations in Indonesia

2015 ◽  
Vol 18 (1) ◽  
pp. 14
Author(s):  
Maria Omega ◽  
Ross T. Barnard
Keyword(s):  
Phylogenetic Trees ◽  
Three Dimensional ◽  
Dimensional Structure ◽  
Genetic Mutations ◽  
Genetic Region ◽  
Chinese Origin ◽  
Different Types ◽  
Glucose 6 Phosphate Dehydrogenase ◽  
The Relationship ◽  
India And China

The aim of this study is to analyze the relationship between the types of G6PD mutations found in Indonesia and the relationships of mutations found in Indonesia to those found in other countries. We summarize the distribution of G6PDs in West Indonesia and East Indonesia. Moreover, we use bioinformatics methods to construct phylogenetic trees and compare the sequences containing the regions amplifi ed by the commonly used PCR primer pairs. Previous work has shown that Mediterranean G6PD and Chinese CoimbraG6PDare distributed in West Indonesia, whilst G6PD mutations in East Indonesia are Jammu/ViangchanG6PD and Chinese Gaohe G6PD. G6PD Jammu/Viangchan was mostly distributed in Flores Island, East Indonesia along with G6PDGaohe. We constructed phylogenetic trees using the G6PD sequences from various regions in Indonesia and other countries. It appears from phylogenetic trees and percentages of identity that FloresIndonesian G6PD defi ciency (Jammu/Viangchan G6PD, originating in India) is 92.5% identical to the G6PD defi ciency of Chinese origin (GaoheG6PD). It was interesting to note that the genetic region containing the Javanese Indonesian G6PD defi ciency (MediterraneanG6PD, fi rst found in Italy) located in the western parts of Indonesia is closely related (99% identity) to the Chinese G6PD defi ciency(Coimbra G6PD). We concludethat G6PD mutations in West Indonesia are closely related to G6PD mutations from China. G6PD mutations in East Indonesia are also closely related to G6PD mutations from India and China, but more distantly, and to different types to those in West Indonesia. A prediction of protein structure was carried out which allowed visualization of the locations of mutation on the three dimensional structure of G6PD. Key words: G6PD, phylogeny, origin, genetic mutations

Determining the orientation of parent β grain from one α variant in titanium alloys

2018 ◽  
Vol 51 (4) ◽  
pp. 1125-1132 ◽  
Author(s):  
Z. B. Zhao ◽  
Q. J. Wang ◽  
H. Wang ◽  
J. R. Liu ◽  
R. Yang
Keyword(s):  
Titanium Alloys ◽  
Habit Plane ◽  
Electron Backscatter Diffraction ◽  
Three Dimensional ◽  
Dimensional Structure ◽  
Plane Normal ◽  
Β Phase ◽  
Microstructural Morphology ◽  
Backscatter Diffraction ◽  
The Relationship

The relationship between the crystallographic orientation and habit plane normal of transformed α laths in titanium alloys is discussed according to the Burgers orientation relationship and the three-dimensional structure of the α lath. A new method (orientation–trace method) is developed to determine the orientation of the parent β phase using the orientation of the α lath, which was measured by electron backscatter diffraction, and the microstructural morphology of that α variant. This approach is validated in a near-α titanium alloy. Moreover, the habit plane normal direction of the transformed α lath can be obtained from the crystallographic orientations of the α lath itself and its parent β grain. The verification and the corresponding discussion show the reliability of this approach.

The magnetotelluric impedance tensor properties with respect to rotations

Geophysics ◽  
1985 ◽  
Vol 50 (10) ◽  
pp. 1610-1617 ◽  
Author(s):  
Simon Spitz
Keyword(s):  
Data Analysis ◽  
Coordinate System ◽  
Three Dimensional ◽  
Dimensional Structure ◽  
Impedance Tensor ◽  
Coordinate Systems ◽  
Magnetotelluric Data ◽  
Conventional Analysis ◽  
Complete Set ◽  
The Relationship

A serious limitation to conventional data analysis is that the data refer mainly to elongated bodies. When three‐dimensional distortions are present, quantitative interpretation based only on the off‐diagonal elements of the conventionally rotated impedance tensor is inadequate, because these off‐diagonal elements are insensitive to the tensor trace. The impedance tensor eigenstate formulation proposed in the literature defines a complete set of parameters suitable for recognition of three‐dimensionality. Generally, though, the eigenvalues do not stand for the off‐diagonal elements of an impedance tensor measured in a physical coordinate system. It is shown how the eigenvalues are modified when the relationship between coordinate system rotations and the eigenstate formulation is clarified. A generalization of the conventional analysis results, but the rotation angle obtained is neither unique nor complete To improve the situation, two new analytical rotation angles are proposed. These angles define two complete intrinsic coordinate systems suitable for magnetotelluric data analysis when a general three‐dimensional structure is involved.

scholarly journals Older workers: stereotypes and occupational self-efficacy

2016 ◽  
Vol 31 (7) ◽  
pp. 1152-1166 ◽  
Author(s):  
Rita Chiesa ◽  
Stefano Toderi ◽  
Paola Dordoni ◽  
Kene Henkens ◽  
Elena Maria Fiabane ◽  
...  
Keyword(s):  
Older Workers ◽  
Self Efficacy ◽  
Age Groups ◽  
Three Dimensional ◽  
Dimensional Structure ◽  
Age Stereotypes ◽  
Content Type ◽  
Moderator Role ◽  
The Relationship ◽  
Organizational Age

Purpose The purpose of this paper is to explore the relationship between organizational age stereotypes and occupational self-efficacy. First, the authors intend to test the measurement invariance of Henkens’s (2005) age stereotypes scale across two age group, respectively, under 50 and 50 years and older. Then, the moderator role of age groups in the relationship between age stereotypes and occupational self-efficacy is investigated. Design/methodology/approach The survey involved a large sample of 4,667 Italian bank sector’s employees. Findings The results show the invariance of the three dimensional structure of organizational stereotypes towards older workers scale: productivity, reliability and adaptability. Furthermore, the moderation is confirmed: the relationship between organizational age stereotypes and occupational self-efficacy is significant only for older respondents. Research limitations/implications Future studies should aim to replicate the findings with longitudinal designs. Practical implications The study suggests the importance to emphasize the positive characteristics of older workers and to reduce the presence of negative age stereotypes in the workplace, especially in order to foster the occupational self-efficacy of older workers. Originality/value The findings are especially relevant in view of the lack of evidence about the relationship between age stereotypes and occupational self-efficacy.

scholarly journals MECHANICAL CHARACTERISTICS FOR COMPOSITE MATERIALS USING COMMERCIAL EPOXY RESINS AND DIFFERENT FILLERS

2021 ◽  
Vol 56 (5) ◽  
pp. 179-185
Author(s):  
Omar A. Amin ◽  
S. A. Hassan ◽  
M. A. Sadek ◽  
M. A. Radwan ◽  
Hany A. Elazab
Keyword(s):  
Mechanical Properties ◽  
Epoxy Resin ◽  
Epoxy Resins ◽  
Three Dimensional ◽  
Mechanical Tests ◽  
Diglycidyl Ether ◽  
Dimensional Structure ◽  
Polymeric Chain ◽  
Hydroxyl Groups ◽  
Different Types

Epoxy resins are thermoset polymers that consist of epoxide groups in their molecular structure. It shows many attractive characteristics like strong adhesion, excellent mechanical strength, low shrinkage, excellent insulator, excellent chemical stability for acidic and basic environments, and microbial resistance due to the presence of hydroxyl groups and ether bonds and its three-dimensional structure. Many of these characteristics can be modified by adding strong bindings in the polymeric chain to give more improved characteristics. This research aims to prepare a composite material using epoxy resin and different types of fillers to achieve resistance to high kinetic energy impact. Experimental work is focused on preparing cured epoxy resin samples by using diglycidyl ether of bisphenol A (DGEBA) resin with tertiary amine as a hardener. In order to obtain different samples with different properties, we add different types of fillers, then mechanical tests are used to measure the mechanical properties of the samples. The results have proved that fiberglass is the best filler added to epoxy resins to improve its mechanical properties.

scholarly journals Diagnostic and Therapeutic Approach to Acute Scaphoid Fractures

2020 ◽  
Vol 48 (02) ◽  
pp. 109-118
Author(s):  
Fernando Polo Simón ◽  
Belén García Medrano ◽  
Pedro J. Delgado Serrano
Keyword(s):  
Present Article ◽  
Therapeutic Approach ◽  
Three Dimensional ◽  
Dimensional Structure ◽  
Carpal Bone ◽  
Review Of The Literature ◽  
Scaphoid Fractures ◽  
Hand Fractures ◽  
Different Types ◽  
Fracture Types

AbstractThe scaphoid is the carpal bone that most often fractures, accounting for up to 70% of carpal fractures and 11% of hand fractures. It is the second most common arm fracture, only surpassed by fractures of the distal radius. Despite being so common, these fractures can be difficult to diagnose and treat due to the anatomic and physiological particularities of the bone, including its precarious vascularization, its complex three-dimensional structure, and its ligament connections, which greatly contribute to the risk of complications such as malunion, pseudoarthrosis and avascular necrosis. Although there are many published studies on the treatment of these injuries, there is still controversy over what is the most suitable one for certain fracture types. The present article is a comprehensive and updated review of the literature. Combining strategies for clinical and radiological diagnosis, we propose a complete algorithm for the diagnosis of scaphoid fractures based on the varying availability of resources, and we also describe the most appropriate therapeutic approach for the different types of acute fractures of this bone.

Pharmaceutical interest of in-silico approaches

2022 ◽  
Vol 0 (0) ◽  
Author(s):  
Dinesh Kumar ◽  
Pooja Sharma ◽  
Ayush Mahajan ◽  
Ravi Dhawan ◽  
Kamal Dua
Keyword(s):  
Molecular Modeling ◽  
In Silico ◽  
Three Dimensional ◽  
Gene Sequencing ◽  
New Drugs ◽  
Dimensional Structure ◽  
Pharmaceutical Applications ◽  
Drug Designing ◽  
Different Types

Abstract The virtual environment within the computer using software performed on the computer is known as in-silico studies. These drugs designing software play a vital task in discovering new drugs in the field of pharmaceuticals. These designing programs and software are employed in gene sequencing, molecular modeling, and in assessing the three-dimensional structure of the molecule, which can further be used in drug designing and development. Drug development and discovery is not only a powerful, extensive, and an interdisciplinary system but also a very complex and time-consuming method. This book chapter mainly focused on different types of in-silico approaches along with their pharmaceutical applications in numerous diseases.

The 3-D Structure of Swirl-Stabilized Flames in a Lean Premixed Multi-Nozzle Can Combustor

2015 ◽  
Author(s):  
Janith Samarasinghe ◽  
Stephen J. Peluso ◽  
Bryan D. Quay ◽  
Domenic A. Santavicca
Keyword(s):  
Gas Turbine ◽  
Tomographic Reconstruction ◽  
Flame Structure ◽  
Combustion Process ◽  
Three Dimensional ◽  
Static Stability ◽  
Dimensional Structure ◽  
Reconstruction Technique ◽  
Flame Stability ◽  
The Relationship

Flame structure is an important aspect of the combustion process which must be considered in the design of gas turbine combustors as it can have a significant effect on the combustor’s static stability (blowoff) and dynamic stability (combustion instability). The relationship between flame structure and flame stability has been studied extensively in single-nozzle combustors. However, relatively few studies have been conducted in multi-nozzle combustor configurations typical of actual gas turbine combustion systems. In this paper, a chemiluminescence-based tomographic reconstruction technique is used to obtain three-dimensional images of the flame structure in a laboratory-scale five-nozzle can combustor. The images reveal the complex three-dimensional structure of this multi-nozzle flame, as well as, the effects of interacting swirling flows, flame-flame interactions and flame-wall interactions on flame structure.

Development of Pipe Flow Generators

2011 ◽  
Vol 233-235 ◽  
pp. 2432-2438
Author(s):  
Song Hao Wang ◽  
Ronald José Doblado Perez ◽  
Ronald García ◽  
Jia Cheng Chen
Keyword(s):  
Rapid Prototyping ◽  
Pipe Flow ◽  
Experimental Studies ◽  
Three Dimensional ◽  
Rotor Design ◽  
Modern Engineering ◽  
Different Types ◽  
Computational Fluid Dynamics Cfd ◽  
Turbine Design ◽  
The Relationship

This study aims to research and develop Pipe Flow Generators. The focus in this paper is on the rotor design for pipes of different sizes. Modern engineering tools such as Computational Fluid Dynamics (CFD) software and Rapid Prototyping technology are utilized to facilitate the numerical and experimental studies. The CFD numerical simulations consist of two and three-dimensional transient and steady analyses. These simulations were conducted to find the relationship between the flow rate, blade geometry and number of blades. During the experimentation process, Rapid Prototyping Technology (RP) was used to fabricate many different types of turbine geometries to test different impeller parameters. RPM and voltages where measured for each turbine design. The study leads to several important findings for better pipe flow generators design.

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