scholarly journals Status iodium pada anak usia sekolah berdasarkan ekskresi iodium urin dan asupan iodium

2019 ◽  
Vol 15 (4) ◽  
pp. 146
Author(s):  
Widya Ayu Kurnia Putri ◽  
Dodik Briawan ◽  
Hidayat Syarief ◽  
Leily Amelia

Iodine status in school-age children determined from iodine urine excretion and iodine intakeBackground: School-age children are more at risk if they experience deficiencies and excess iodine. The concentration of iodine in urine is a good biomarker for assessing iodine intake, 90% of iodine intake will be excreted through urine. Objective: This study aimed to analyze the iodine status of school-age children based on urinary iodine excretion (UIE) and iodine intake.Method: The study design used a cross-sectional study on 44 healthy school-aged children in Bogor Regency. Subject selection was done purposively in healthy 5th-grade elementary school students. The data taken in this study was urine iodine excretion concentration and food recall (1x24 hours). Data were analyzed using descriptive analysis and Pearson correlation test.Results: Median iodine excretion concentration in urine was 157 μg/l and the average daily iodine intake of children was 83.29 mg/day. Conclusion: The concentration of iodine excretion in the urine of the children is in the category of sufficient iodine as recommended by WHO / UNICEF / ICCID while the daily intake of iodine for children is still in the less category. The results showed that there was no association of iodine daily intake with iodine excretion concentration in urine(p=0.469).

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Mariacarla Moleti ◽  
Maria Di Mauro ◽  
Giuseppe Paola ◽  
Antonella Olivieri ◽  
Francesco Vermiglio

AbstractIodine is an essential component of the thyroid hormones, thyroxine and triiodothyronine. Its availability strictly depends on iodine content of foods, which may vary from very low to very high. Inadequate iodine intake (deficiency or excess) may affect thyroid function resulting in hypothyroidism or hyperthyroidism. Based on median urinary iodine concentrations, epidemiological criteria have been established for the categorization and monitoring of nutritional iodine status of a population (or subgroups of populations). Additional methods for iodine intake assessment include measurement of thyroid size (by thyroid palpation or ultrasonography) and of biochemical parameters, such as neonatal thyroid stimulating hormone, thyroglobulin and thyroid hormones.Recent studies carried out in overweight/obese children and adults provide evidence that body mass index (BMI) may significantly influence the above indicators, thus theoretically affecting the epidemiological evaluation of nutritional iodine status in populations.In this short review, we analyze current knowledge on the effects of overweight and obesity on indicators of adequacy and monitoring of iodine status, namely urinary iodine excretion and thyroid volume and echogenicity.Data on urinary iodine excretion in overweight/obese children are divergent, as both increased and reduced levels have been reported in overweight/obese children compared to normal-weight controls.Whether gastrointestinal surgery may affect iodine absorption and lead to iodine deficiency in patients undergoing bariatric surgery has been evaluated in a limited number of studies, which excluded iodine deficiency, thus suggesting that supplements usually recommended after bariatric surgery do not need to include iodine.Albeit limited, evidence on thyroid volume and obesity is consistent with a direct relationship between thyroid volume and BMI, irrespective of nutritional iodine status. Finally, a higher frequency of thyroid hypoechoic pattern has been described in overweight/obese children. This finding has been recently related to an increased adipocyte infiltration and thyroid parenchyma imbibition mediated by inflammatory cytokines and should be considered when the frequency of thyroid hypoechoic pattern is used as non-invasive marker to indirectly assess thyroid autoimmunity in monitoring Universal Salt Iodization programs. Further studies, specifically addressing the role of schoolchildren body mass index as a factor potentially influencing iodine intake indicators are needed.


Author(s):  
Yozen Fuse ◽  
Yoshiya Ito ◽  
Yoshimasa Shishiba ◽  
Minoru Irie

Abstract Context Japan has been regarded as a long-standing iodine sufficient country without iodine fortification; however, data on nationwide iodine status is lacking. Objective This study aimed to characterize the iodine status in Japan. Methods From 2014 through 2019 a nationwide school-based survey was conducted across all districts in Japan. Urinary iodine concentration (UIC), creatinine (Cr) concentration and anthropometry were assessed in healthy school-aged children (SAC) aged 6 to 12 years. Their iodine status is regarded as generally representative of the nation's iodine status. Results A total of 32,025 children participated. The overall median UIC was 269 μg/L which was within the WHO’s adequacy range. There was a regional difference in UIC values within 14 regions, and the lowest and highest median UIC were found in Tanegashima Island (209 μg/L) and Nakashibetsu, Hokkaido (1,071 μg/L), respectively. The median UIC ≥ 300 μg/L was observed in 12 out of 46 regions. By using estimated 24-h urinary iodine excretion (UIE), the prevalence of SAC exceeding the upper tolerable limit of iodine for Japanese children was from 5.2 to 13.7%. The UIC values did not change with age, BSA and BMI percentile, while the Cr concentration simultaneously increased suggesting the effect of urinary creatinine on UI/Cr and estimated 24-h UIE values. Conclusions The iodine intake of Japanese people is adequate, but in some areas it is excessive. The incidence and prevalence of thyroid disorders associated with iodine intake should be obtained especially in the areas where high amounts of iodine are consumed.


1998 ◽  
Vol 80 (6) ◽  
pp. 529-535 ◽  
Author(s):  
Helen J. Lightowler ◽  
G. Jill Davies

I intake and I deficiency were investigated in thirty vegans (eleven males and nineteen females) consuming their habitual diet. I intake was estimated using the chemical analysis of 4 d weighed duplicate diet collections. The probability of I-deficiency disorders (IDD) was judged from the measurement of urinary I excretion in 24 h urine specimens during the 4 d. There was wide variation in I intake. Mean I intake in males was lower than the reference nutrient intake (RNI; Department of Health, 1991) and mean intake in females was above the RNI, although 36% males and 63% females had I intakes below the lower RNI. Mean I intake in subjects who consumed seaweed (n 3) was in excess of the RNI, and approached the provisional maximum tolerable daily intake (World Health Organization/Food and Agriculture Organization Joint Expert Committee on Food Additives, 1989). The probability of IDD in the group investigated was moderate to severe: three of five subgroups were classified as moderate and two subgroups were classified as severe IDD possibility. The findings highlight that vegans are an ‘at risk’ group for I deficiency. The I status of vegans and the subclinical effects of low I intakes and infrequent high I intakes on thyroid function in this group should be further studied. Our work has also raised the question of adequate I intakes in groups where cow's milk is not consumed, and has exposed a need for more research in this area.


2016 ◽  
Vol 86 (4) ◽  
pp. 628-633 ◽  
Author(s):  
Wen Chen ◽  
Xiang Li ◽  
Xiaohui Guo ◽  
Jun Shen ◽  
Long Tan ◽  
...  

2021 ◽  
pp. 1-33
Author(s):  
K Beckford ◽  
CA Grimes ◽  
C Margerison ◽  
LJ Riddell ◽  
SA Skeaff ◽  
...  

ABSTRACT Dietary recalls have been used previously to identify food sources of iodine in Australian schoolchildren. Dietary assessment can provide information on the relative contributions of individual food groups which can be related to a robust objective measure of daily intake (24hr urinary iodine excretion (UIE)). In Australia, the government has mandated the use of iodised salt in breadmaking to address iodine deficiency. The aim of this study was to determine the dietary intake and food sources of iodine to assess their contribution to iodine excretion (UIE) in a sample of Australian schoolchildren. In 2011-13 UIE was assessed using a single 24-hour urine sample and dietary intake was assessed using one 24-hour dietary recall in a convenience sample of primary schoolchildren from schools in Victoria, Australia. Of the 454 children with a valid recall and urine sample 55% were male (average age 10.1) (1.3(SD) years). Mean (SD) UIE and dietary iodine intake were 108(54) and 172(74) μg/day, respectively. Dietary assessment indicated that bread and milk were the main food sources of iodine, contributing 27% and 25%, respectively, to dietary iodine. Milk but not bread intake was positively associated with UIE. Multiple regression (adjusted for school cluster, age and gender) indicated that for every 100g increase in milk consumption, there was a 3μg/day increase in UIE (β=4.0 (0.9)(SE), P<0.001). In conclusion, both bread and milk were important contributors to dietary iodine intake however consumption of bread was not associated with daily iodine excretion in this group of Australian schoolchildren.


Author(s):  
Nilratan Majumder ◽  
Balaram Sutradhar ◽  
Saradindu Riang ◽  
Shib Sekhar Datta

Background: Due to excess metabolic demand of iodine in pregnancy, pregnant women and lactating mother and their neonates are most vulnerable of iodine deficiency disorder. Urinary iodine excretion is a good marker of recent dietary iodine intake. Thus, present study was conducted to assess the iodine status and median urinary iodine excretion (UIE μg/lit) among pregnant and non-pregnant women of Tripura.Methods: Tribal and Bengali pregnant and non-pregnant women from Bokafa and Jolaibari Block of South Tripura district were included in the study. Urinary iodine excretion was done using simple micro plate method. Salt iodine was estimated using iodometric titration. All the tests were performed at CNRT Lab, ICMR, India.Results: Total number of subjects included in this study was 1071. Total number of urine samples collected from pregnant and non-pregnant women was 538 and 533 respectively. Median value of UIE in pregnant and non-pregnant women of Tripura was 155.0µg/L and 130.0µg/L. In pregnant women percentage prevalence of severe (<20µg/L), moderate (20-49µg/L) and mild iodine deficiency (50-149µg/L) was found in 4.1%, 15.1% and 29.6% subjects. In case of non-pregnant women severe (<20µg/L), moderate (20-49µg/L) and mild iodine deficiency (50-99µg/L) was found in 0.6%, 9.6%, 27.8% subjects respectively. The overall prevalence of iodine deficiency was found in 48.8% pregnant women, compared to 38.0% non-pregnant subjects.Conclusions: Efforts towards universal salt iodization need to be stepped-up in Sub-Himalayan region (NE part of India) and pregnant and lactating mothers may be targeted with alternate iodine supplements (Colloidal Iodine).


2018 ◽  
Vol 48 (6) ◽  
pp. 873-885
Author(s):  
Naima Saeid ◽  
Anass Rami ◽  
Samir Mounach ◽  
Abdeslam Hamrani ◽  
Asmaa El Hamdouchi ◽  
...  

Purpose Iodine deficiency has several adverse effects on human growth and development and it is categorized collectively as iodine deficiency disorders (IDDs). Recent estimations showed that 29.8 per cent of school-age children have insufficient iodine intake. Salt iodization is widely accepted as the best method for increasing iodine intake. In 1995, Morocco adopted the universal salt iodization strategy to reduce iodine deficiency and consequently prevent and control IDDs. This study aims to determine the benefit of this strategy on schoolchildren and adolescent by assessing iodine intake and evaluating iodine deficiency. Design/methodology/approach This transversal study was conducted on 131 children and adolescents. Iodine intake was assessed using a food frequency questionnaire. Iodine status was evaluated on 24-h urine samples and the creatinine excretion was used to validate completeness of urine collection. Findings The medians of urinary iodine excretion and concentration were 77 µg/day and 96 µg/L, respectively. Overall, 72.5 per cent are deficient, so mild and moderate iodine deficiencies were reported in 58 per cent and 14.5 per cent, respectively, and no child exhibited severe deficiency. A significant difference was reported between iodine deficiency and, sex and age; iodine deficiency was more pronounced in boys and children under eight years. In this study, iodine status in deficient children does not change with the consumption pattern of dairy products and eggs, and results showed no significant association (p > 0.05). However, fish consumption was significantly associated to urinary iodine concentration = 100 µg/L (p = 0.044). Average UIC in school-aged children is still inadequate and consumption of foods high in iodine remains very insufficient. Therefore, additional efforts must focus on nutritional education of Moroccan school-aged children. Originality/value In the author’s knowledge, this is the first study evaluating schoolchildren iodine status by 24-h iodine collection; the study reported association of iodine deficiency with dietary habit concerning sources of food rich on iodine.


2014 ◽  
Vol 112 (10) ◽  
pp. 1715-1723 ◽  
Author(s):  
Sarah C. Bath ◽  
Michelle L. Sleeth ◽  
Marianne McKenna ◽  
Alan Walter ◽  
Andrew Taylor ◽  
...  

As intra-thyroidal iodine stores should be maximised before conception to facilitate the increased thyroid hormone production during pregnancy, women who are planning to become pregnant should ideally consume 150 μg iodine/d (US RDA). As few UK data exist for this population group, a cross-sectional study was carried out at the University of Surrey to assess the iodine intake and status of women of childbearing age. Total iodine excretion was measured from 24 h urine samples in fifty-seven women; iodine intake was estimated by assuming that 90 % of ingested iodine was excreted. The average iodine intake was also estimated from 48 h food diaries that the participants completed. The median urinary iodine concentration value (63·1 μg/l) indicated the group to be mildly iodine deficient by WHO criteria. By contrast, the median 24 h urinary iodine excretion value (149·8 μg/24 h) indicated a relatively low risk of iodine deficiency. The median estimated iodine intake, extrapolated from urinary excretion, was 167 μg/d, whereas it was lower, at 123 μg/d, when estimated from the 48 h food diaries. Iodine intake estimated from the food diaries and 24 h urinary iodine excretion were strongly correlated (r 0·75, P< 0·001). The intake of milk, eggs and dairy products was positively associated with iodine status. The iodine status of this UK cohort is probably a best-case scenario as the women were mostly nutrition students and were recruited in the winter when milk-iodine content is at its highest; further study in more representative cohorts of UK women is required. The present study highlights the need for revised cut-off values for iodine deficiency that are method- and age group-specific.


2015 ◽  
Vol 8 (1) ◽  
Author(s):  
Prem Raj Shakya ◽  
Basanta Gelal ◽  
Binod Kumar Lal Das ◽  
Madhab Lamsal ◽  
Paras Kumar Pokharel ◽  
...  

2021 ◽  
pp. 13-18
Author(s):  
N.S. Shevchenko ◽  
◽  
H.О. Shlieienkova ◽  
K.V. Voloshyn ◽  
T.V. Zimnytska ◽  
...  

One of the most common conditions resulting from micronutrient deficiency is iodine deficiency. Purpose — to evaluate the current state of iodine supply in schoolchildren living in the North-Eastern region of Ukraine, including children with digestive diseases and inflammatory joint diseases. Materials and methods. Target group: 86 people (11.8±2.71 years), which included patients with digestive diseases (DD) (26.7%) and juvenile idiopathic arthritis (JIA) (60.5%). Methods: dietary iodine intake evaluation by urinary iodine concentration (Sandell–Kolthoff reaction), followed by calculation of the median. Results. Median urinary iodine excretion was at the lower normal range and amounted to 104.98 μg/l [QR: 59.8; 180.1] in the examined children. Only 51.2% of children had adequate iodine provision; mild iodine deficiency (ID) was diagnosed in 29.1% (Ме=81,91μg/l [QR: 64.26; 90.58]); moderate — 17.4% (Ме=36,19 μg/l [QR: 33.54; 42.24]); severe — in 2.3% of the surveyed (Ме 14,02 μg/l [QR: 12.34; 15.70]). The median urinary iodine excretion in children with somatic diseases was significantly lower than in children of the control group and amounted to 97.26 μg/l [QR 53.7; 148.3] versus 183.71 μg/l [QR 104.4; 287.4], (p=0.003). Conclusions. School-age children have a high incidence of iodine deficiency (51.2%). Often encountered in childhood diseases (DD and JIA) are accompanied by insufficiency of iodine supply. The research was carried out in accordance with the principles of the Helsinki declaration. The study protocol was approved by the Local Ethics Committee of all participating institution. The informed consent of the patient was obtained for conducting the studies. No conflict of interest was declared by the author. Key words: iodine deficiency, school-age children, the level of iodine excretion.


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