Survivorship and quality of life after treatment for nasopharyngeal cancer

2014 ◽  
pp. 211-229
Author(s):  
Minh Tam Truong
Keyword(s):  
Quality Of Life ◽  
Nasopharyngeal Cancer

scholarly journals Quality of Life, Toxicity and Unmet Needs in Nasopharyngeal Cancer Survivors

2020 ◽  
Vol 10 ◽  
Author(s):  
Lachlan McDowell ◽  
June Corry ◽  
Jolie Ringash ◽  
Danny Rischin
Keyword(s):  
Quality Of Life ◽  
Cancer Survivors ◽  
Unmet Needs ◽  
Nasopharyngeal Cancer

Randomized Phase II Trial of Concurrent Cisplatin-Radiotherapy With or Without Neoadjuvant Docetaxel and Cisplatin in Advanced Nasopharyngeal Carcinoma

2009 ◽  
Vol 27 (2) ◽  
pp. 242-249 ◽  
Author(s):  
Edwin P. Hui ◽  
Brigette B. Ma ◽  
Sing F. Leung ◽  
Ann D. King ◽  
Frankie Mo ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Neoadjuvant Chemotherapy ◽  
Positive Impact ◽  
Nasopharyngeal Cancer ◽  
Progression Free Survival ◽  
Hazard Ratio ◽  
High Rate ◽  
Phase Iii ◽  
Tumor Control

Purpose To compare the toxicities, tumor control, survival, and quality of life of nasopharyngeal cancer (NPC) patients treated with sequential neoadjuvant chemotherapy followed by concurrent cisplatin-radiotherapy (CRT) or CRT alone. Patients and Methods Previously untreated stage III to IVB NPC were randomly assigned to (1) neoadjuvant docetaxel 75 mg/m2 and cisplatin 75 mg/m2 every 3 weeks for two cycles, followed by cisplatin 40 mg/m2/wk concurrent with radiotherapy, or (2) CRT alone. Planned accrual was 30 patients per arm to detect 20% difference of toxicities based on 95% CIs. Results From November 2002 to November 2004, 65 eligible patients were randomly assigned to neoadjuvant chemotherapy followed by CRT (n = 34) or CRT alone (n = 31). There was a high rate of grade 3/4 neutropenia (97%) but not neutropenic fever (12%) during neoadjuvant chemotherapy. No significant differences in rates of acute toxicities were observed between the two arms during CRT. Dose intensities of concurrent cisplatin, late RT toxicities and quality of life scores were comparable in both arms. The 3-year progression-free survival for neoadjuvant versus control arm was 88.2% and 59.5% (hazard ratio = 0.49; 95% CI, 0.20 to 1.19; P = .12). The 3-year overall survival for neoadjuvant versus control arm was 94.1% and 67.7% (hazard ratio = 0.24; 95% CI, 0.078 to 0.73; P = .012). Conclusion Neoadjuvant docetaxel-cisplatin followed by CRT was well tolerated with a manageable toxicity profile that allowed subsequent delivery of full-dose CRT. Preliminary results suggested a positive impact on survival. A phase III study to definitively test this neoadjuvant-concurrent strategy is warranted.

scholarly journals Endoscopy of Nasopharyngeal Cancer

1994 ◽  
Vol 1 (2) ◽  
pp. 63-68 ◽  
Author(s):  
Brian B. Burkey ◽  
Robert H. Ossoff
Keyword(s):  
Quality Of Life ◽  
High Risk ◽  
High Resolution ◽  
Local Anesthesia ◽  
Nasopharyngeal Cancer ◽  
Cost Effective ◽  
Cost Effective Approach ◽  
The World

Nasopharyngeal cancer (NPC) is a unique disease with increasing interest for many physicians due to its unusual etiology, histology, and epidemiology. The recent era of fiberoptic endoscopy now provides the clinician with better tools for the screening, diagnosis, staging, and follow-up of NPC. The use of high resolution flexible and rigid nasopharyngoscopy gives the physician an opportunity for a more sensitive examination in a higher proportion of patients. Ultimately, this will allow for earlier diagnosis of NPC, and improved prognosis and better quality of life for the patients with this disease. Also, by allowing the clinician to perform directed biopsies of the nasopharynx under local anesthesia, fiberoptic nasopharyngoscopy allows a less morbid and more cost-effective approach towards this disease, including screening protocols in certain high risk regions of the world.

scholarly journals Xerostomia Severity and Quality of Life After Nasopharyngeal Cancer Radiotherapy: Intensity Modulated vs Two-dimensional Radiation Therapy in Indonesia

2021 ◽  
Vol 11 (2) ◽  
pp. 32-37
Author(s):  
Soehartati Argadikoesoema Gondhowiardjo ◽  
Nikrial Dewin ◽  
Andreas Ronald ◽  
Vito Filbert Jayalie ◽  
Handoko Handoko ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Radiation Therapy ◽  
Nasopharyngeal Cancer ◽  
Two Dimensional ◽  
Cancer Radiotherapy ◽  
Intensity Modulated

Correlation of chemotherapy costs with quality of life in nasopharyngeal cancer patients

2020 ◽  
Vol 30 (6) ◽  
Author(s):  
Achmad Chusnu Romdhoni ◽  
Riskha Aulia ◽  
Ririn Prasetyo Utaminingtyas ◽  
Christopher Paul Alderman ◽  
Keyword(s):  
Quality Of Life ◽  
Cancer Patients ◽  
Nasopharyngeal Cancer ◽  
Chemotherapy Cycle ◽  
The Third ◽  
Eortc Qlq C30 ◽  
Notable Increase ◽  
Eortc Qlq ◽  
The Cost

AbstractBackgroundNasopharyngeal cancer (NPC) is the most common neck/head cancer occurring in Indonesia and is the fourth most malignant after breast cancer, cervical cancer, and lung cancer. It is known that the cost of chemotherapy may not be separated from quality of life (QoL) to reflect the success of therapy, especially in cancer patients. Thus, studies on the correlation between chemotherapy cost and the QoL in NPC patients are needed.MethodsThe participants were recruited by a consecutive sampling method. All patients diagnosed with NPC using a paclitaxel-cisplatin chemotherapy regimen in August–March 2019 for first until the third chemotherapy cycle were assessed for their the chemotherapy cost and QoL before the first chemotherapy cycle and after the third cycle using the EORTC QLQ-C30 questionnaire. Chemotherapy cost and QoL were analyzed using SPSS version 20 to find out the correlation.ResultsData from 26 patients showed a notable increase in the QoL after the third chemotherapy cycle. Thus, there was a relationship between chemotherapy cost and QoL in NPC patients. The total cost of chemotherapy increased with the increase in cycles of chemotherapy. We further analyzed the correlation between QoL and the cost of chemotherapy. We found that there was a correlation between the cost and the aspects of global health status, the QoL.ConclusionsIt is concluded that chemotherapy that is followed by the increase in cost in chemotherapy improves the QoL.

Long-Term Trajectory of Quality of Life in Nasopharyngeal Cancer Patients

2014 ◽  
Vol 90 (1) ◽  
pp. S705
Author(s):  
A. Kiang ◽  
K.N. Cheung ◽  
V.K. Weinberg ◽  
E. Shugard ◽  
J.M. Quivey ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Cancer Patients ◽  
Nasopharyngeal Cancer
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