QRFP receptor (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database
Keyword(s):
The human gene encoding the QRFP receptor (nomenclature as agreed by the NC-IUPHAR Subcommittee on the QRFP receptor [16]; QRFPR, formerly known as the Peptide P518 receptor), previously designated as an orphan GPCR receptor was identified in 2001 by Lee et al. from a hypothalamus cDNA library [15]. However, the reported cDNA (AF411117) is a chimera with bases 1-127 derived from chromosome 1 and bases 155-1368 derived from chromosome 4. When corrected, QRFPR (also referred to as SP9155 or AQ27) encodes a 431 amino acid protein that shares sequence similarities in the transmembrane spanning regions with other peptide receptors. These include neuropeptide FF2 (38%), neuropeptide Y2 (37%) and galanin Gal1 (35%) receptors.
1994 ◽
Vol 14
(4)
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pp. 643-653
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1998 ◽
Vol 180
(17)
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pp. 4753-4756
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1999 ◽
Vol 181
(5)
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pp. 1464-1473
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1992 ◽
Vol 267
(26)
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pp. 18631-18638
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2005 ◽
Vol 187
(15)
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pp. 5067-5074
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2017 ◽
Vol 4
(4)
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pp. 625-628
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