The pcd Gene Encoding Piperideine-6-Carboxylate Dehydrogenase Involved in Biosynthesis of α-Aminoadipic Acid Is Located in the Cephamycin Cluster ofStreptomyces clavuligerus
1998 ◽
Vol 180
(17)
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pp. 4753-4756
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ABSTRACT Three open reading frames (ORFs) have been located downstream ofcefE in the cephamycin C gene cluster of Streptomyces clavuligerus. ORF13 (pcd) encodes a 496-amino-acid protein (molecular weight [MW], 52,488) with an N-terminal amino acid sequence identical to that of pure piperideine-6-carboxylate dehydrogenase. ORF14 (cmcT) encodes a 523-amino-acid protein (MW, 54,232) analogous to Streptomyces proteins for efflux and resistance to antibiotics. ORF15 (pbp74) encodes a high molecular weight penicillin-binding protein (MW, 74,094).
1998 ◽
Vol 64
(5)
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pp. 1650-1656
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1994 ◽
Vol 14
(4)
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pp. 643-653
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1999 ◽
Vol 181
(5)
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pp. 1464-1473
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Keyword(s):
2005 ◽
Vol 187
(15)
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pp. 5067-5074
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Keyword(s):
1970 ◽
Vol 36
(2)
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pp. 229-240
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