Anemia ferropénica crónica: síndrome de Plummer-Vinson (Paterson-Brown-Kelly)

2021 ◽  
Vol 64 (2) ◽  
pp. 22-25
Author(s):  
Adriana Zapata González ◽  
María Elena Uc Miam ◽  
Felipe Irineo Hernández Rosales ◽  
Alberto Mandujano González ◽  
Karime Berenice Ramos Santos
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Clinical History ◽  
Deficiency Anemia ◽  
Precancerous Condition ◽  
Esophageal Web ◽  
Squamous Cell Esophageal Cancer ◽  
Plummer Vinson Syndrome ◽  
History Of ◽  
First Contact

Plummer-Vinson syndrome (Paterson-Brown-Kelly) is a rare entity, characterized by dysphagia, esophageal web formation, and iron deficiency anemia. We present the case of a 46-year-old woman with a clinical history of iron deficiency anemia who subsequently presents dysphagia and odynophagia. A subcricoid web that was successfully broken with the endoscope was found. First contact doctors should be familiar with the symptoms of Plummer-Vinson syndrome, and take them into account, when addressing a patient with the classic triad. Since the syndrome is a precancerous condition with high malignant potential, early diagnosis and treatment is of utmost importance for better prognosis. Keywords: Plummer-Vinson syndrome; chronic iron deficiency anemia; esophageal membrane; squamous cell esophageal cancer; Paterson-Brown-Kelly syndrome.

scholarly journals A Case of Plummer-Vinson Syndrome Esophageal Web Dysphagia treated by Dilatation with Cuffed Endotracheal Tube

2011 ◽  
Vol 2 (3) ◽  
pp. 161-165 ◽  
Author(s):  
Sudhir Naik ◽  
Sarika S Naik ◽  
S Ravishankara ◽  
MC Shivakumar ◽  
Mohan K Appaji
Keyword(s):  
Iron Deficiency ◽  
Blood Transfusion ◽  
Endotracheal Tube ◽  
Iron Deficiency Anemia ◽  
Deficiency Anemia ◽  
White Female ◽  
Barium Swallow ◽  
Cuffed Endotracheal Tube ◽  
Esophageal Web ◽  
Plummer Vinson Syndrome

ABSTRACT Background/objectives Plummer-Vinson syndrome also known as sideropenic dysphagia is a disease characterized by chronic iron-deficiency anemia, dysphagia and esophageal web. It commonly affects white female in the 4th to 7th decade. Most of the dysphagia and iron deficiency can be treated by iron supplementation and rarely web dilatation is needed. Setting Department of ENT, Head and Neck Surgery and Anesthesia, KVG Medical College, Sullia, Karnataka, India. Case report A 36-year-old female with dysphagia of 10 months and iron-deficiency anemia with a small upper esophageal web seen on upper GI endoscopy and barium swallow. Intervention Conservative line of management with blood transfusion and dilatation of the web with cuffed endotracheal tube. Results A good symptomatic and radiological improvement was seen after blood transfusion and web dilatation with cuffed endotracheal tube. Conclusion Cuffed endotracheal tube dilatation is a better way of managing upper esophageal webs with minimal complications under general anesthesia.

scholarly journals Case report on Plummer Vinson syndrome

2019 ◽  
Vol 8 (10) ◽  
pp. 2334
Author(s):  
Chanukya Vanam ◽  
Durga Prasad Thammisetty
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Iron Supplementation ◽  
General Medicine ◽  
Deficiency Anemia ◽  
Systemic Effects ◽  
Plummer Vinson Syndrome ◽  
History Of ◽  
Male Patients

Plummer Vinson syndrome or Paterson-Brown-Kelly syndrome is a rare disorder is characterized by a triad of iron deficiency anemia, post-cricoid dysphagia and upper oesophageal web. This is a condition that is hypothesized to occur in people with long-term iron-deficiency anemia. It is more prevalent in females than in male patients. This disorder is characterized by iron deficiency anemia, post-cricoid dysphagia and oesophageal webs, symptoms typically progress over a period of six months and often include other systemic effects such as angular cheilitis, glossitis, and spooning of the fingernails. Here we report a case of 38 years female admitted in general medicine female with complaints of breathlessness and tightness of chest relieving after vomiting and had history of anemia, dysphagia insidious in onset and dysphagia associated with solid food over a year on examination patient was found to be gross pallor, angular cheilitis, spoon-shaped nails of fingers and toes. The lab findings were hemoglobin of 7.8 g/dl, serum ferritin levels 7.23 ng/ml, vitamin B12 175.2 pg/ml and upper oesophageal endoscopy revealed oesophageal web in the post-cricoid region. Treatment of Plummer Vinson syndrome includes iron supplementation followed by endotracheal dilation if necessary.

scholarly journals Plummer-Vinson Syndrome: A Case Report

2011 ◽  
Vol 31 (3) ◽  
pp. 254-256
Author(s):  
DS Gedam ◽  
J Mandliya ◽  
M Verma
Keyword(s):  
Case Report ◽  
Iron Deficiency ◽  
Ethnic Group ◽  
Iron Deficiency Anemia ◽  
Deficiency Anemia ◽  
White Female ◽  
Esophageal Web ◽  
Plummer Vinson Syndrome ◽  
Classical Triad

Plummer-Vinson also known as sideropenic dysphagia is a disease that is characterized by classical triad of iron deficiency anemia, dysphagia and esophageal web. It is known to mostly affect white female mainly, but cases have been reported from other ethnic group in the literature. Treatment is very promising especially when it is not associated with carcinoma. DOI: http://dx.doi.org/10.3126/jnps.v31i3.4259 J Nep Paedtr Soc 2011;31(3): 254-256

scholarly journals PLUMMER VINSON SYNDROME - is it common in males?

2015 ◽  
Vol 52 (3) ◽  
pp. 250-252 ◽  
Author(s):  
Satvinder Singh BAKSHI
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Oral Iron ◽  
Deficiency Anemia ◽  
Gastrointestinal Malignancies ◽  
Esophageal Web ◽  
Plummer Vinson Syndrome ◽  
Increased Risk ◽  
Male Patients ◽  
Males And Females

BackgroundPlummer-Vinson syndrome is characterized by a triad of dysphagia, iron deficiency anemia and esophageal web. Most of the patients are middle aged women in the fourth to seventh decade of life.ObjectiveVery few cases of Plummer-Vinson syndrome affecting males have been reported. Here we report a series of male patients found to be suffering from Plummer-Vinson syndrome.MethodsFive males presented to us with dysphagia and fatigue of various durations, from April to August, 2012.ResultsThese patients were found to have iron deficiency anemia and esophageal web on subsequent investigations and were treated successfully with oral iron therapy.ConclusionPlummer-Vinson syndrome is common in both males and females and can be successfully treated with oral iron therapy. The patients have an increased risk of developing gastrointestinal malignancies and should be thoroughly evaluated for the same.

scholarly journals Occurrence of neonatal diarrhea in calves with iron-deficiency anemia

2019 ◽  
Vol 73 (1) ◽  
pp. 1-9
Author(s):  
Radisa Prodanovic ◽  
Sreten Nedic ◽  
Oliver Radanovic ◽  
Vesna Milicevic ◽  
Ivan Vujanac ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Iron Status ◽  
Enterotoxigenic Escherichia Coli ◽  
Deficiency Anemia ◽  
Fecal Samples ◽  
Gut Function ◽  
History Of ◽  
Neonatal Calves ◽  
Diarrheic Calves

Introduction. Neonatal calves are often deficient in iron. Accumulating evidence indicates that iron status is associated with disease pathologies including diarrhea. Our objective was to examine the association between iron status and gut function in neonatal calves with and without a history of calf diarrhea. Materials and Methods. Calves were divided into two groups based on their history of diarrhea; the first group were diarrheic calves (n=6) and the second group were non-diarrheic healthy calves (n=6). Blood samples (n=12) were collected at day 12 of age and erythrogram determination and measurements of serum iron and total iron binding capacity were performed. Hematological values were measured using an automatic analyzer, and biochemical properties were determined spectrophotometrically. Fecal samples were obtained from all calves and pH measured using semi quantitative test strips as well as being examined by bacterial cultivation for enterotoxigenic Escherichia coli, Salmonella spp. and Clostridium perfringens, by RT-PCR for the presence of bovine rotavirus, bovine coronavirus and bovine viral diarrhea virus, and by microscopy for the presence of Cryptosporidium parvum. Results and Conclusions. There were significant iron-related changes for most hematological indices in diarrheic calves; and iron (Fe) deficiency and microcytic, hypochromic anemia were diagnosed. The pH of the feces was significantly higher in diarrheic calves than in the non-diarrheic healthy group (P<0.01). All fecal samples were negative for the analyzed enteric pathogens. According to the results obtained, calves experiencing iron deficiency anemia exhibit changes in gut function leading to diarrhea as compared with a matched group of healthy calves.

Kết quả thai kỳ ở phụ nữ mang thai có thay van tim cơ học

2018 ◽  
Vol 15 (4) ◽  
pp. 52-57
Author(s):  
Minh Thang Tran ◽  
Minh Toan Le ◽  
Tran Thao Nguyen Nguyen ◽  
Minh Tam Le ◽  
Quang Vinh Truong
Keyword(s):  
Iron Deficiency ◽  
Prospective Study ◽  
Pregnant Women ◽  
Iron Deficiency Anemia ◽  
Deficiency Anemia ◽  
Medical Conditions ◽  
History Of ◽  
Criteria For Diagnosis ◽  
A Prospective Study

A prospective study were identified on 110 pregnants women with iron deficiency anemia, who had treated with iron dose depending on the degree of iron deficiency. We studied in pregnant women aged 6-20 weeks, with no history of medical conditions as well as hematological pathologies. Criteria for diagnosis of iron deficiency anemia is Hb

Cerebral Sinovenous Thrombosis Related to Iron Deficiency Anemia As a Result of Severe Menorrhagia: A Case Report

Blood ◽  
2012 ◽  
Vol 120 (21) ◽  
pp. 5143-5143
Author(s):  
Fernando F. Corrales-Medina ◽  
Nidra Rodriguez ◽  
Daniela E Egas-Bejar ◽  
Zoila Valdivia-Ascuna ◽  
Leon Grant ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Brain Mri ◽  
Deficiency Anemia ◽  
Cerebral Veins ◽  
Vein Of Galen ◽  
Straight Sinus ◽  
Cerebral Sinovenous Thrombosis ◽  
Sinovenous Thrombosis ◽  
History Of

Abstract Abstract 5143 Cerebral sinovenous thrombosis (CSVT) is a rare condition with a wide spectrum of non-specific symptoms, which makes it occasionally difficult to diagnose. CSVT has been associated with various etiologies including dehydration, hypercoagulable states, neoplasmic invasion of a venous sinus, intracranial and systemic infections, use of oral contraceptives, puerperium and pregnancy. Although iron deficiency anemia (IDA) has been reported as a cause of CSVT in several pediatric cases, this association is extremely rare. To our knowledge, IDA-associated CSVT in teenagers has been rarely reported. Here, we present the case of a 13-year old female with complete thrombosis of the vein of Galen, the straight sinus, and the left internal cerebral vein related to iron deficiency anemia as a result of severe menorrhagia. She initially presented with three-week history of headaches, nausea and vomiting. She was initially diagnosed and treated for bacterial sinusitis by her primary pediatrician, without symptom relief. She then suffered a syncopal episode, reason why she was evaluated at our institution. Initial laboratories revealed a slightly increased PT (15. 6 secs), hemoglobin of 5. 1 g/dL, MCV 63. 6 and D-dimer 1. 31. Non-contrast brain CT demonstrated no evidence of stroke, hemorrhage or mass. However, an abnormal hyperdensity in the straight sinus, inferior sagittal sinus, vein of Galen, and deep cerebral veins, were suggestive of venous thrombosis. Findings were then confirmed by brain MRI/MRV/MRA and CT angiogram. A bleeding work-up performed based on her history of heavy menses was normal. Her ferritin level was significantly decreased (6 ng/mL). Iron supplementation was initiated as well as progestin-only hormonal therapy for menstrual cycle regulation. The patient's clinical status improved back to baseline during her 8-day admission. She was discharged home on anticoagulation with scheduled follow up. Brain MRI/MRV six months later showed patency of the cerebral veins and dural venous sinuses. IDA should be considered as an underlying cause of CSVT in pediatric patients, particularly in patients with other risk factors for thrombosis including dehydration, regardless of their age. Early recognition and management of CSVT is critical to minimize the possibility of permanent neurologic damage. Physicians should be aware of the non-specific signs and symptoms of CSVT and should have a high index of suspicion in patients with anemia. Disclosures: No relevant conflicts of interest to declare.

scholarly journals Impact Of Maternal Factors on Birth weight In Salah- Aldeen general Hospital/Tikrit City

2021 ◽  
Vol 05 (1) ◽  
pp. 1-13
Author(s):  
Sahar Talab ◽  
Sarab Jasim
Keyword(s):  
Diabetes Mellitus ◽  
Birth Weight ◽  
Iron Deficiency ◽  
Low Birth Weight ◽  
General Hospital ◽  
Iron Deficiency Anemia ◽  
Previous History ◽  
Deficiency Anemia ◽  
Normal Birth ◽  
History Of

Birth weight is a crucial determinant of the developmental potential of the newborn. Birth weight is the body weight of a baby at its birth. The range of normal is between 2.5 and 4.5 kilograms (5.5 and 9.9 lb). On average, babies of south Asian and Chinese heritage weigh about 3.26 kilograms (7.2 lb). Abnormal newborn weights are associated with negative effects on the health and survival of the baby and the mother. World Health Organization has defined low birth weight as birth weight less than 2,500 grams. Giving birth to a low-birth-weight infant is influenced by several factors. This study aimed to identify key determinants that influence the frequency of normal and low birth weight in Salah Al-Deen general Hospital in Tikrit city-Iraq. This study is a Cross- sectional study, was conducted in obstetric department in Salah Al-Deen general hospital during the period from 1st Feb to the 31st of August 2020. The study sample included full term babies (gestational age 37-42 week) chosen by using a convenient sampling method selecting 197 delivered babies with their mothers. Data collection done by face-to-face interview, using the structured questionnaire developed by the researcher include the following information: Information regarding the mother included demographic variables, reproductive health, medical and obstetrical history and antenatal care visits, use of ferrous sulfate and other supplements during pregnancy. Birth weight was measured at birth, to the nearest 50 g, with the nude infant lying on the available scale. Zero adjustment of the scale was frequently done to ensure accuracy of the readings. Birth weight was categorized into two as low birth weight (birth weight < 2500 grams), and normal birth weight (birth weight ≥ 2500 grams). The current study showed that prevalence of low birth weight was (2.4%), macrosomia (15.6%) and normal birth weight was (82%). The study showed that the low birth weight was higher among primigravida (3.4%), than multigravida women (1.7%) and that the low birth weight was higher among 1st and 2nd birth order (3.4%), (6.7%) respectively while it was (0%) among the 3rd baby order. Previous history of Diabetes Mellitus was associated with 0(0%) low birth weight babies and (2.6%) of those women without Diabetes Mellitus had low birth weight babies. Those with history of iron deficiency anemia was more prone to had babies with low birth weight (3.1%), versus those without history of iron deficiency anemia (1.3%). Those with history of hypertension more prone to had babies with low birth weight (4%), versus those without history of iron deficiency anemia (2.2%). The current study showed that those with ferrous sulfate supplements had lower proportion of babies with low birth weight (1.2%), versus those without supplements (7.7%), this relation statistically significant. This study has demonstrated that the younger maternal age, mother with diabetes mellitus, hypertension and irregular antenatal care had babies with lower birth weight. Previous history of low birth weight also is a predisposing factor for low birth weight.

scholarly journals A Rare Case Report on Plummer-Vinson Syndrome with a Complication of Oral Cancer in a South-Asian Woman

2020 ◽  
Vol 14 (1) ◽  
Author(s):  
Ayisha Ayisha ◽  
Sheema Masood Ali
Keyword(s):  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Iron Deficiency ◽  
Cell Carcinoma ◽  
Iron Deficiency Anemia ◽  
Squamous Cell ◽  
Whole Body ◽  
Deficiency Anemia ◽  
Plummer Vinson Syndrome ◽  
Increased Risk

Plummer-Vinson syndrome (PVS), also called "Paterson-Brown-Kelly syndrome“, is a rare medical syndrome generally affecting middle-aged women. Iron deficiency anemia is the prime etiological factor and other probable factors include malnutrition, genetic predisposition, or autoimmune processes characterized by three distinctive features: iron deficiency anemia, dysphagia, and esophageal web. The dysphagia is generally painless and intermittent or progressive over years, restricted to solids, and associated with weight loss. The exact pathogenesis of PVS is still indistinguishable, but it is interconnected with iron deficiency anemia. Plummer-Vinson syndrome, if left untreated, carries an increased risk of developing squamous cell carcinoma of the upper alimentary tract.In this case report, a 40-year-old female patient presented long-standing dysphagia for months, which progressively developed to postcricoid squamous cell carcinoma by the time she approached to medical treatment. Diagnosis was confirmed through laboratory tests, showing iron deficiency anemia and whole-body positron emission tomography-computed tomography (PET-CT) presenting squamous cell carcinoma in postcricoid region (hypopharynx).

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