scholarly journals Seroprevalence of hepatitis b, c and HIV among patients attending a multispecialty hospital: An 8 year old retrospective study

2021 ◽  
Vol 7 (4) ◽  
pp. 174-176
Author(s):  
Minha Majeed Kak ◽  
Arya Jyoti ◽  
Anurag Nath ◽  
Priyanka Rastogi ◽  
Sachin Kumar
Keyword(s):  
Retrospective Study ◽  
Hepatitis B

scholarly journals MP633PREVALENCE AND RISK FACTORS OF HEPATITIS B VIRUS AMONG PREVALENT HEMODIALYSIS PATIENTS IN EGYPT: RETROSPECTIVE STUDY

2016 ◽  
Vol 31 (suppl_1) ◽  
pp. i551-i551
Author(s):  
Essam M Khedr ◽  
Aber H Attallah ◽  
Cherry Reda kamel ◽  
Maha AbdELMoneim Behairy
Keyword(s):  
Risk Factors ◽  
Retrospective Study ◽  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Hemodialysis Patients ◽  
B Virus

scholarly journals Effects of maternal hepatitis B surface antigen positive status on the pregnancy outcomes: A retrospective study in Xiamen, China, 2011-2018

PLoS ONE ◽  
2020 ◽  
Vol 15 (3) ◽  
pp. e0229732 ◽  
Author(s):  
Yan Zhao ◽  
Yin-ling Chen ◽  
Hai-qu Song ◽  
Pei-ying Huang ◽  
Li-ying Wang ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Hepatitis B ◽  
Surface Antigen ◽  
Pregnancy Outcomes ◽  
Hepatitis B Surface Antigen

scholarly journals A retrospective study of administration of vaccination for hepatitis B among newborn infants prior to hospital discharge at a midwestern tertiary care center

Vaccine ◽  
2015 ◽  
Vol 33 (20) ◽  
pp. 2316-2321 ◽  
Author(s):  
Helen I. Myers ◽  
Cassandra N. Spracklen ◽  
Kelli K. Ryckman ◽  
Jeffrey C. Murray
Keyword(s):  
Retrospective Study ◽  
Hepatitis B ◽  
Hospital Discharge ◽  
Care Center ◽  
Tertiary Care ◽  
Newborn Infants ◽  
Tertiary Care Center

scholarly journals High Dose of Lamivudine and Resistance in Patients with Chronic Hepatitis B

2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Hamid Ullah Wani ◽  
Saad Al Kaabi ◽  
Manik Sharma ◽  
Rajvir Singh ◽  
Anil John ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Retrospective Study ◽  
Hepatitis B ◽  
Chronic Hepatitis B ◽  
Standard Dose ◽  
High Dose ◽  
Lamivudine Therapy ◽  
Daily Dose ◽  
The Mean ◽  
Emergence Of Resistance

Background. Lamivudine is the most affordable drug used for chronic hepatitis B and has a high safety profile. With the daily dose of 100 mg there is progressive appearance of resistance to lamivudine therapy. In our study we used 150 mg of lamivudine daily as a standard dose which warrants further exploration for the efficacy of the drug. Aims of the Study. To assess the efficacy of lamivudine 150 mg daily on resistance in patients with chronic hepatitis B. Methods. This retrospective study consists of 53 patients with chronic hepatitis B treated with 150 mg of lamivudine daily. The biochemical and virological response to the treatment were recorded at a 1-year and 2-, 3-, 4-, and 5-year period and time of emergence of resistance to the treatment was noted. Results. The mean age of the patients was 54 years with 80% being males. The resistance to lamivudine 150 mg daily at 1 year and 2, 3, and 5 years was 12.5%, 22.5%, 37.5%, and 60%, respectively, which is much less compared to the standard dose of 100 mg of lamivudine. Conclusions. Lamivudine is safe and a higher dose of 150 mg daily delays the resistance in patients with chronic hepatitis B.

scholarly journals Effect of Positive Hepatitis B Surface Antigen on The Risk of Synchronous Liver Metastasis: A Retrospective Study of 868 Consecutive Patients of Newly Diagnosed Gastric Cancer

2020 ◽  
Author(s):  
Tingya Wang ◽  
Haijun Zhang
Keyword(s):  
Risk Factors ◽  
Gastric Cancer ◽  
Logistic Regression ◽  
Regression Analysis ◽  
Retrospective Study ◽  
Liver Metastasis ◽  
Hepatitis B ◽  
Surface Antigen ◽  
Hepatitis B Surface Antigen ◽  
Newly Diagnosed

Abstract Background. The study aimed to explore the influence of hepatitis B virus (HBV) infection on the risk of synchronous gastric cancer liver metastasis (synGCLM).Methods. This was a retrospective study which enrolled 868 patients with newly diagnosed gastric cancer (GC). The study compared the prevalence of synGCLM between hepatitis B surface antigen (HBsAg)-positive (HBsAg+) and -negative (HBsAg-) patients. Logistic regression analysis was utilized to analyze the risk factors for synGCLM. Among patients with and without synGCLM, aspartate aminotransferase to platelet ratio index (APRI), liver fibrosis-4 index (FIB-4) and hepatitis B e antigen (HBeAg) status were further analyzed. Results. The prevalence of synGCLM in the HBsAg+ patients was higher than that in the HBsAg- patients, which was statistically significant (P = 0.025). Multivariate logistic regression analysis demonstrated that HBsAg, the elevated level of carcinoembryonic antigen (CEA), alpha-fetoprotein (AFP), γ-glutamyltransferase (GGT) and alkaline phosphatase (ALP) were risk factors for synGCLM. Among the HBsAg+ patients, both ARPI and FIB-4 were significantly higher in the patients with synGCLM (synGCLM+) than those without synGCLM (synGCLM-) (ARPI: P = 0.045; FIB-4: P = 0.047); HBeAg positivity was detected in 20.0% of synGCLM+ patients compared to 6.0% of synGCLM- patients, but the difference was of no significance (P = 0.190). Conclusions. HBV infection significantly increases the risk of synGCLM, and elevated ARPI and FIB-4 may be pro-metastatic especially among the HBsAg+ GC patients.

scholarly journals Seroepidemiology of Hepatitis B and C Virus Infections: A Five-Year Retrospective Study Among Blood Donors in Saboba District in the Northern Region of Ghana

2021 ◽  
Author(s):  
Abel Makija Nlankpe ◽  
Patrick Kwesi Owiafi ◽  
David Adedia ◽  
Jacob Nabei Nignan ◽  
Precious Kwablah Kwadzokpui
Keyword(s):  
Retrospective Study ◽  
Hepatitis B ◽  
Blood Donors ◽  
Adult Population ◽  
Public Health Education ◽  
Northern Region ◽  
Female Group ◽  
Seroprevalence Rate ◽  
Virus Infections ◽  
Hcv Coinfection

Abstract Background and Objectives: Chronic hepatitis B and C infections are capable of progressing to liver cirrhosis and hepatocellular carcinoma. Globally, it has been estimated that over 2 billion and 170 million people are living with hepatitis B and C infections, respectively. Ghana remains one of the highly endemic countries challenged by continues spread of these viral agents in Africa. This study aimed to determine the seroprevalence and trend of Hepatitis B and C coinfections among blood donors in Saboba District of the Northern Region of Ghana. Methods: A five-year hospital based retrospective study was carried out among 8,605 blood donors comprising 8517 males and 88 females using data on blood donors from Saboba Assemblies of God Hospital located in the Saboba District in the Northern Region of Ghana from 2013 to 2017. Blood bank records on HBV and HCV potential blood donors who visited the hospital to donate blood was retrieved. Donor demographic details, i.e. age and gender were also recovered. Donors who were registered to the hospital but were not residents of the Northern Region were excluded from the study. Donors with incomplete records were also excluded from the study. The data was managed using Microsoft Excel spreadsheet 2016 and analysed using GraphPad Prism statistical software. Results: The overall prevalence of asymptomatic viral hepatitis B and C infection in the general adult population was 9.59% and 12.71%, respectively, with an HBV/HCV coinfection rate of 2.23%. The number of donors generally declined with advancement in years from 2038 (23.68%) since 2013 to as low as 1169 (13.59%) in 2016, except for 2017 where a sharp increase of 1926 (22.38%) was observed. The first and second highest proportions of donors fell within the age categories of 20-29 [51.53% (4434)] and 30-39 [32.90% (2831)]. Seroprevalence rate of HBV, HCV and HBV/HCV coinfection rates were generally higher among the female group than observed among the male category. The year-to-year variation in HBV, HCV and HBV/HCV infection was statistically significant. The highest year-to-year HBV seropositivity rate was 11.48% in the year 2013, while that for HCV and HBV/HCV coinfection was 16.24% and 5.85% respectively both documented in the year 2014. HBV and HBV/HCV coinfection rate was highest among donors aged <20 years old, while HCV seroprevalence was highest among donors aged 50-59 years old. Conclusion: Seroprevalence of HBV and HCV among donors in the Saboba District of the Northern Region of Ghana is endemic. The HBV/HCV coinfections rate also raises serious concern owing to its high prevalence rate among the younger age. Intensive public health education coupled with mobile screening and mass vaccination of seronegative individuals is advised so as to help curb further spread of the infection and in effect help safeguard the health status of potential donors in the district.

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