scholarly journals Massive vagal schwannoma in an 11-year-old girl

2021 ◽  
Author(s):  
Noah Feit ◽  
Conall Fitzgerald ◽  
Timothy McLean ◽  
Richard Wong
Keyword(s):  
Molecular Pathology ◽  
Unusual Case ◽  
Tumor Resection ◽  
Young Girl ◽  
Operative Approach

We describe an unusual case of a young girl presenting with a large vagal schwannoma necessitating a transcervical-mandibulotomy approach for total tumor resection. The presentation is unique due to the size of the lesion, the patient’s age, the operative approach, and molecular pathology.

An unusual case of incomplete isosexual precocious puberty in a young girl with juvenile hypothyroidism

2014 ◽  
Vol 3 (3) ◽  
pp. 188
Author(s):  
PranabKumar Sahana ◽  
Nilanjan Sengupta ◽  
Chanchal Das ◽  
Ranen Dasgupta
Keyword(s):  
Precocious Puberty ◽  
Unusual Case ◽  
Young Girl

Giant Serpentine Aneurysm of the Posterior Cerebral Artery

Neurosurgery ◽  
1982 ◽  
Vol 11 (2) ◽  
pp. 271-276 ◽  
Author(s):  
Akira Fukamachi ◽  
Masabumi Hirato ◽  
Tetsuo Wakao ◽  
Jun-ichi Kawafuchi
Keyword(s):  
Cerebral Artery ◽  
Unusual Case ◽  
Posterior Cerebral Artery ◽  
Operative Approach ◽  
Pterional Approach ◽  
Serpentine Aneurysm ◽  
Temporary Clipping

Abstract We are reporting an unusual case of a giant serpentine aneurysm of the posterior cerebral artery (PCA). We were unable to find a report in the literature of a similar aneurysm. The microsurgical pterional approach was used for temporary clipping of the P-2 segment of the PCA, and the aneurysm was trapped successfully and excised. The discussion includes the operative approach to the giant serpentine aneurysm.

scholarly journals Recurrence of glioblastoma multiforme in a childhood: A case report

2020 ◽  
Vol 8 (3) ◽  
pp. 407-412
Author(s):  
Fahimma ◽  
Yuyun Yueniwati ◽  
Dessika Rahmawati ◽  
Dessika Rahmawati
Keyword(s):  
Case Report ◽  
Glioblastoma Multiforme ◽  
Unusual Case ◽  
Treatment Options ◽  
Tumor Resection ◽  
Left Hemiparesis ◽  
Therapeutic Approaches ◽  
Imaging Evaluation ◽  
Initial Manifestation ◽  
Different Characteristics

GBM is a highly aggressive malignant tumor that rarely happens in children. Pediatric GBM is the primary cause of death in children with brain neoplasms. Treatment of GBM is a difficult and challenging condition, especially in pediatric GBM. Surgical tumor resection combined with chemoradiotherapy suggests as standard therapeutic approaches for GBM. However, the recurrence of GBM is an inevitable event and can occur in more than 90% of patients. We present an unusual case of an 11-years-old girl with recurrence of GBM. She complained of progressive headache and left hemiparesis as an initial manifestation. She was diagnosed with GBM three years before. Near-total surgical resection followed with chemotherapy, and radiotherapy was done after the diagnosis. Head imaging showed a smaller lesion, and her symptoms were improved significantly. Two years after, she was admitted to the hospital with worsening symptoms. Imaging evaluation showed the enlargement of tumor lesions. Recurrence of GBM is a great challenge to manage, and there are no well-defined management protocols. Several studies suggest that treatment options may follow the adult patients' approach, but pediatric GBM has significantly different characteristics than adults.

scholarly journals Pulmonary Hyalinizing Granuloma Mimicking Primary Lung Cancer: An Unusual Case Involving a Pulmonary Tumor

2020 ◽  
Vol 2020 ◽  
pp. 1-3
Author(s):  
Hideki Marushima ◽  
Hiroki Sakai ◽  
Reimi Yoneyama ◽  
Hiroyuki Kimura ◽  
Tomoyuki Miyazawa ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Unusual Case ◽  
Solitary Pulmonary Nodule ◽  
Tumor Resection ◽  
Primary Lung Cancer ◽  
Rare Condition ◽  
Histopathological Analysis ◽  
Radiographic Findings ◽  
Benign Condition ◽  
Uncommon Location

Pulmonary hyalinizing granuloma is a very rare benign condition. This study describes a case involving pulmonary hyalinizing granuloma in a 76-year-old man who presented with a solitary pulmonary nodule, determined through chest radiography and computed tomography, that mimicked primary lung cancer. To establish a definitive diagnosis, tumor resection was performed with histopathological analysis indicating pulmonary hyalinizing granuloma. Radiographic findings in previously reported cases showed that most patients had well-defined margins and usually bilateral, multiple lesions. In our case; however, the solitary ill-defined tumor mimicking lung cancer is an uncommon location for this rare condition.

scholarly journals Concurrence of chromosome 6 chromothripsis and glioblastoma metastasis

2017 ◽  
Vol 126 (5) ◽  
pp. 1472-1478 ◽  
Author(s):  
Robert C. Rennert ◽  
Reid R. Hoshide ◽  
Jason W. Signorelli ◽  
Deirdre Amaro ◽  
Jayson A. Sack ◽  
...  
Keyword(s):  
Current Literature ◽  
Copy Number ◽  
Unusual Case ◽  
Tumor Resection ◽  
The Cancer Genome Atlas ◽  
Resected Specimen ◽  
Chromosome 6 ◽  
Data Set ◽  
Cancer Genome Atlas ◽  
Genome Atlas

The authors report an unusual case of a widely metastatic glioblastoma. DNA copy number microarray profile of the resected specimen revealed complex rearrangements found throughout chromosome 6, a phenomenon known as chromothripsis. Such chromothripsis pattern was not observed in 50 nonmetastatic glioblastoma specimens analyzed. Analysis of the 1000+ gliomas profiled by The Cancer Genome Atlas (TCGA) data set revealed one case of chromosome 6 chromothripsis resembling the case described here. This TCGA patient died within 6 months of undergoing tumor resection. Implications of these findings are reviewed in the context of the current literature.

scholarly journals UNUSUAL CASE OF ANGIOSARCOMA OF LIVER PRESENTING WITH PULMONARY METASTASIS IN A YOUNG GIRL

2017 ◽  
Vol 6 (69) ◽  
pp. 4966-4967
Author(s):  
Daspin D ◽  
Tom Aby ◽  
Ramalingam Sivaraman ◽  
Francis G
Keyword(s):  
Pulmonary Metastasis ◽  
Unusual Case ◽  
Young Girl

scholarly journals An unusual case of nonocclusive mesenteric ischemia in a young girl

2012 ◽  
Vol 16 (1) ◽  
pp. 28-30 ◽  
Author(s):  
Arvind K. Baronia ◽  
Ratender Singh ◽  
Tanmoy Ghatak
Keyword(s):  
Mesenteric Ischemia ◽  
Unusual Case ◽  
Young Girl ◽  
Nonocclusive Mesenteric Ischemia

scholarly journals Delayed Bladder Perforation Related to Immediate Single Dose Intravesical Doxorubicin Instillation After TURBT: A Case Report and Literature Review

2021 ◽  
Vol 14 ◽  
pp. 117954762098615 ◽  
Author(s):  
Adel Alrabadi ◽  
Mohannad Abuhamad ◽  
Hammam Mansi ◽  
Sohaib Alhamss ◽  
Nadwa Bustami ◽  
...  
Keyword(s):  
Single Dose ◽  
Unusual Case ◽  
Tumor Resection ◽  
Bladder Perforation ◽  
Muscle Invasive Bladder Cancer ◽  
Case Presentation ◽  
Life Threatening ◽  
Muscle Invasive ◽  
High Index Of Suspicion ◽  
Surgical Treatments

Introduction: Intravesical chemotherapy instillation immediately after tumor resection is a well-known practice in the management of non-muscle invasive bladder cancer. Despite being largely well tolerated in most cases, it is not devoid of severe and life-threatening complications. Case Presentation: We present an unusual case of bladder perforation that happened 2 weeks after bladder tumor resection. The patient had received single dose intra-vesical instillation of doxorubicin after TUR-BT. Conservative managements failed to achieve bladder healing; as a result, open surgical repair was performed. To the best of our knowledge, this is the first reported case of bladder perforation after intra-vesical doxorubicin instillation. Conclusion: The occurrence of such a rare serious complication in a mostly safe intervention must be taken into consideration. A high index of suspicion, timely management, and proceeding to more invasive surgical treatments when necessary are cornerstones in the management and preserving the bladder.

Decellularized bone extracellular matrix in skeletal tissue engineering

2020 ◽  
Vol 48 (3) ◽  
pp. 755-764
Author(s):  
Benjamin B. Rothrauff ◽  
Rocky S. Tuan
Keyword(s):  
Tissue Engineering ◽  
Bone Regeneration ◽  
Tissue Regeneration ◽  
Animal Studies ◽  
Tumor Resection ◽  
Regenerative Capacity ◽  
Skeletal Tissue ◽  
Large Bone

Bone possesses an intrinsic regenerative capacity, which can be compromised by aging, disease, trauma, and iatrogenesis (e.g. tumor resection, pharmacological). At present, autografts and allografts are the principal biological treatments available to replace large bone segments, but both entail several limitations that reduce wider use and consistent success. The use of decellularized extracellular matrices (ECM), often derived from xenogeneic sources, has been shown to favorably influence the immune response to injury and promote site-appropriate tissue regeneration. Decellularized bone ECM (dbECM), utilized in several forms — whole organ, particles, hydrogels — has shown promise in both in vitro and in vivo animal studies to promote osteogenic differentiation of stem/progenitor cells and enhance bone regeneration. However, dbECM has yet to be investigated in clinical studies, which are needed to determine the relative efficacy of this emerging biomaterial as compared with established treatments. This mini-review highlights the recent exploration of dbECM as a biomaterial for skeletal tissue engineering and considers modifications on its future use to more consistently promote bone regeneration.

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