scholarly journals COVID-19 and rhinovirus in pediatric: are there differences in clinical presentation and outcomes?

2021 ◽  
Author(s):  
Maria Fernanda Pereira ◽  
Priscila Suguita ◽  
Nadia Litvinov ◽  
Sylvia Farhat ◽  
Carolina Lazari ◽  
...  
Keyword(s):  
Prospective Study ◽  
Respiratory Virus ◽  
Pediatric Patients ◽  
Clinical Presentation ◽  
Clinical Course ◽  
Pediatric Population ◽  
Virus Infections ◽  
Single Center ◽  
Clinical Context ◽  
Respiratory Virus Infections

The dynamic of SARS-CoV-2 and other respiratory virus in children and adolescents is relevant in clinical context. There are few studies comparing clinical course in COVID-19 (coronavirus disease) and other respiratory virus in pediatric patients. The aim of this study was to compare demographics and clinical features, exams abnormalities, and outcomes in SARS-CoV-2 and other respiratory virus infections in a pediatric population. This was a single-center prospective study, between April 17 to September 30, 2020. We evaluated 76 pediatric COVID-19 and 157 other respiratory virus infections. Rhinovirus occurred in 132/157(84%). COVID-19 patients were significantly older, had more fever (69% versus 50%; p=0.01), pneumonia (22% versus 5%; p<0.01), myalgia (29% versus 8%; p=0.001), headache (31% versus 14%; p=0.01) and worse outcomes than those with other respiratory virus infections. Our data emphasizes differences in clinical presentation and outcomes between pediatric COVID-19 and rhinovirus infections.

scholarly journals Pediatric Crohn's Disease

2018 ◽  
Vol 31 (02) ◽  
pp. 080-088 ◽  
Author(s):  
Daniel von Allmen
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Older Patients ◽  
Pediatric Patients ◽  
Clinical Presentation ◽  
Surgical Intervention ◽  
Clinical Course ◽  
Pediatric Population ◽  
Medical Treatments ◽  
Course Of Disease

AbstractThe incidence of Crohn's disease in the pediatric population is increasing. While pediatric patients with Crohn's disease exhibit many of the characteristics of older patients, there are important differences in the clinical presentation and course of disease that can impact the clinical decisions made during treatment. The majority of children are diagnosed in the early teen years, but subgroups of very early onset and infantile Crohn's present much earlier and have a unique clinical course. Treatment paradigms follow the traditional laddered approach, but growth and development represent special considerations that must be given to pediatric-specific complications of the treatment and disease. Surgical intervention is an important component of Crohn's management and is often employed to allow improved nutritional intake or decrease reliance on medical treatments that compromise growth.

scholarly journals Burden, Etiology, and Risk Factors of Respiratory Virus Infections Among Symptomatic Preterm Infants in the Tropics: A Retrospective Single-Center Cohort Study

2018 ◽  
Vol 67 (10) ◽  
pp. 1603-1609 ◽  
Author(s):  
Kee Thai Yeo ◽  
Rowena de la Puerta ◽  
Nancy Wen Sim Tee ◽  
Koh Cheng Thoon ◽  
Victor S Rajadurai ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cohort Study ◽  
Preterm Infants ◽  
Respiratory Virus ◽  
Virus Infections ◽  
Single Center ◽  
The Tropics ◽  
Respiratory Virus Infections

scholarly journals Rhinovirus Infection in Children with Acute Bronchiolitis and Its Impact on Recurrent Wheezing and Asthma Development

2020 ◽  
Vol 8 (10) ◽  
pp. 1620
Author(s):  
Carlotta Biagi ◽  
Alessandro Rocca ◽  
Giulia Poletti ◽  
Marianna Fabi ◽  
Marcello Lanari
Keyword(s):  
Clinical Presentation ◽  
Clinical Course ◽  
Pediatric Population ◽  
Acute Bronchiolitis ◽  
Virus Infections ◽  
Recurrent Wheezing ◽  
Multiple Virus ◽  
Syncytial Virus

Acute bronchiolitis represents the leading cause of hospitalization in infants. Together with a respiratory syncytial virus, rhinovirus (RV) is one of the most common pathogens associated with bronchiolitis, and its genetic diversity (>150 types) makes the recurrence of RV infections each year quite typical. The frequency of RV infection and co-infection with other viruses and its impact on the clinical course of bronchiolitis have been studied by several authors with controversial results. Some studies demonstrate that multiple virus infections result in more severe clinical presentation and a higher risk of complications, whereas other studies suggest no influence on clinical course. Moreover, RV bronchiolitis has been reported to potentially contribute to the development of long-term sequelae, such as recurrent wheezing and asthma, in the pediatric population. In the present review, we summarize the most recent findings of the role of RV infection in children with acute bronchiolitis, its impact on subsequent asthma development, and the implication in clinical practice.

Immunizations and vaccines: a decade of successes and reversals, and a call for ‘vaccine diplomacy’

2019 ◽  
Vol 11 (5) ◽  
pp. 331-333 ◽  
Author(s):  
Peter J Hotez
Keyword(s):  
Respiratory Virus ◽  
Neglected Tropical Diseases ◽  
Tropical Diseases ◽  
Virus Infections ◽  
Vaccination Programs ◽  
Vaccine Preventable Diseases ◽  
Health Gains ◽  
Potential Development ◽  
Respiratory Virus Infections ◽  
New Vaccines

Abstract Over the last decade we have seen extraordinary public health gains due to expansions in global vaccination programs led by United Nations (UN) agencies, including Gavi, the Vaccine Alliance, UNICEF and the WHO. These initiatives have reduced childhood deaths from measles, tetanus and other vaccine-preventable diseases by almost one half. There is additional excitement over the potential development and introduction of new vaccines to prevent highly lethal respiratory virus infections, as well as tuberculosis, malaria, HIV/AIDS and several neglected tropical diseases. However, these successes are under threat due to political instability, conflict and an accelerating antivaccine movement. New initiatives in vaccine diplomacy will be required to combat these challenges.

scholarly journals Histological evidence of pulmonary micro-thrombosis and vasculitis in life-threatening respiratory virus diseases

2020 ◽  
Author(s):  
Heather W Dolby ◽  
Philippe M D Potey ◽  
Annika Wilder-Smith ◽  
Sara Clohisey ◽  
Jonathan E Millar ◽  
...  
Keyword(s):  
Respiratory Virus ◽  
Virus Infections ◽  
Virus Diseases ◽  
Histological Evidence ◽  
Life Threatening ◽  
Respiratory Virus Infections

Abstract Pulmonary micro-thrombosis and vasculitis occur in fatal COVID-19. To determine if these processes occur in other life-threatening respiratory virus infections we identified autopsy studies of fatal influenza(n=455 patients), SARS(n=37), MERS(n=2), adenovirus(n=34) and RSV(n=30). Histological evidence of thrombosis was frequently present in adults with fatal influenza and SARS, with vasculitis also reported.

Sign in / Sign up

Export Citation Format

Share Document