scholarly journals CoViD-19 Infection and Acute Pancreatitis with Pancreatic Pseudocyst. Is There a Causal Relationship?

Author(s):  
Giuseppe Galloro ◽  
Angelo Zullo ◽  
Alessia Chini ◽  
Rosa Maione ◽  
Matteo Pollastro ◽  
...  

This report shows two cases of acute pancreatitis in CoViD-19 patients with development of pancreatic pseudocyst treated with lumen apposing stent and hypothesize on the possible cause-and-effect relationship between the infection and pancreatitis. Considering literature data and direct experience, it’s possible that coronavirus causes a direct damage to pancreatic tissue.

2020 ◽  
Vol 21 (20) ◽  
pp. 7580
Author(s):  
Michael Webb ◽  
Dionisia P. Sideris

Mitochondrial dysfunction is associated with ageing, but the detailed causal relationship between the two is still unclear. We review the major phenomenological manifestations of mitochondrial age-related dysfunction including biochemical, regulatory and energetic features. We conclude that the complexity of these processes and their inter-relationships are still not fully understood and at this point it seems unlikely that a single linear cause and effect relationship between any specific aspect of mitochondrial biology and ageing can be established in either direction.


Author(s):  
S. V. Velikanov

The issues of temporal sign of a causal relationship in Criminalistics is considered. The problematics of the asymmetry of the direction of time and causality have been worked out, approaches to clarifying the sequence and simultaneity of the event- cause and the event-consequence in Criminalistics have been proposed.


1996 ◽  
Vol 110 (6) ◽  
pp. 602-603 ◽  
Author(s):  
Hironori Shimizu ◽  
Akira Kodama

AbstractWe present a case of severe acute pancreatitis in a 14-year-old boy that may have been caused by hyperparathyroidism. The clue to finding the parathyroid adenoma was the hypercalcaemia. Although the patient did have acute pancreatitis, no therapy had been effective until the discovery of the parathyroid adenoma. After the excision of the parathyroid adenoma, the function of the pancreas and serum calcium returned to normal. This result suggests a certain cause and effect relationship between hyperparathyroidism and acute pancreatitis.


2021 ◽  
Vol 17 (2) ◽  
pp. 9-14
Author(s):  
Elena O. Igonina

The diversity of the interpretation of the cause-and-effect relationship by various subjects of law enforcement activity leads to the birth of an absolutely newthing in itself a new process. Then the causal relationship, being a derived category, acquires a new meaning and a new essence, which leads to its modification, contradictions in judicial practice and conflicts between decision-making subjects.


2021 ◽  
Vol 8 (1) ◽  
pp. e000538
Author(s):  
Alejandra Tepox-Padrón ◽  
Rafael Ambrosio Bernal-Mendez ◽  
Gilberto Duarte-Medrano ◽  
Adriana Fabiola Romano-Munive ◽  
Milton Mairena-Valle ◽  
...  

Idiopathic acute recurrent pancreatitis (IARP) is defined as at least two episodes of acute pancreatitis with the complete or near-complete resolution of symptoms and signs of pancreatitis between episodes, without an identified cause. There is a paucity of information about the usefulness of endoscopic ultrasound (EUS) in IARP.ObjectivesTo determine the diagnostic yield of EUS in IARP.DesignA retrospective study was performed in patients with IARP evaluated by EUS between January 2009 and December 2016. Follow-up assessments of acute pancreatitis recurrence were carried out.ResultsSeventy-three patients with 102 EUS procedures were included. EUS was able to identify the cause of IARP in 55 patients (75.3%). The most common findings were chronic pancreatitis in 27 patients (49.1%), followed by lithiasic pathology in 24 patients (43.6%), and intraductal papillary mucinous neoplasm in four patients (7.3%). A directed treatment against EUS findings had a protective tendency associated with the final resolution of recurrence. There were no complications reported.ConclusionEUS performed in patients with IARP helped to identify a possible cause in 2/3 of the cases. The majority of patients have a treatable disease.


2013 ◽  
Vol 39 (1) ◽  
Author(s):  
Metin Uysalol ◽  
Levent Cem Mutlu ◽  
Gamze Varol Saracoglu ◽  
Erkut Karasu ◽  
Savas Guzel ◽  
...  

2011 ◽  
Vol 91 (2) ◽  
pp. 129-137 ◽  
Author(s):  
Mark T.U. Barone ◽  
Luiz Menna-Barreto

2021 ◽  
Vol 11 (9) ◽  
pp. 1838-1843
Author(s):  
Xiaohong Zhou ◽  
Xuzhong Hao ◽  
Feifei He

To investigate whether exosomes (exo) derived from human umbilical cord mesenchymal stem cells (huMSCs) and microRNA (miRNA)-342 have a protective effect on severe acute pancreatitis (SAP). Human umbilical cord blood was collected to extract huMSC-exo. With sham-operated mice as control group (n = 10), the other mice were induced to SAP model (n = 20), while 10 of the SAP mice received treatment with huMSC-exo. ELISA was performed to determine amylase and TAP level as well as inflammatory factors and HE staining to evaluate pathological changes of pancreatic tissue. The expression of miR-342 and Shh, Ptchl, and Smo in the Hh signal pathway was detected using RT-qPCR. The expression of miR-342 and the mRNA expression of Shh, Ptchl, and Smo was higher than that in model group (p < 0.05). The level of serum amylase, trypsinogen, and IFN-γ,Fasl, and IL-6 was upregulated in pancreas tissues of SAP mice relative to healthy mice, but their levels were decreased upon treatment with huMSC-exo and slightly higher than those of the control group, just not significantly. Collectively, the huMSC-exo may activate the Hh signaling pathway by regulating the expression of miR-342 increasing the expression of Shh, Ptchl, and Smo, and thereby healing of damaged pancreatic tissues in SAP.


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