Frequency and intensity of symptoms in patients with chronic rhinosinusitis

Introduction/Objective. Chronic rhinosinusitis is one of the most frequent chronic disorders which significantly influences the patients? quality of life. The objectiv? of this paper was to examine which are the most frequent and intensive symptoms in patients with chronic rhinosinusitis, and also to determine whether there is a correlation between a subjective assessment of the disease as a whole and individual symptoms. Methods. The study encircled 90 patients with clinical diagnosis of chronic rhinosinusitis that was endoscopically proven and computer tomography of the nose and paranasal sinuses. Every possible symptom was recorded in every patient (nasal congestion, nasal discharge, facial pain/pressure, reduction or loss of smell, headache, fatigue, cough, halitosis and ear pain/fullness), the intensity of every possible symptom as well as the disorder as a whole. The patients assessed the intensity of their symptoms on the visual analogue scale. Results. Nose congestion is the most frequent symptom. It occured in 82 patients (91.1%), followed by nasal discharge in 81 patients (90%) and there was no difference in frequency of these two symptoms. Nasal discharge has been recorded as the most intensive symptom (x? = 5.4) and it is significantly more intensive in comparison to nasal congestion which was the second on the intesity list (x? = 4.1, p = 0.002). All other symptoms were significantly less frequently and less intensive. The average intensity value of the disease as a whole is the same as the average intensity value of the nasal discharge (x? = 5.4) while the average intensity values of all other symptoms are statistically significantly lower than the average intensity value of the disease as a whole; in all comparisons p < 0.001. Conclusion. Nasal congestion and nasal discharge are the most common symptoms in the patients with chronic rhinosinusitis. Nasal discharge is the most intensive symptom in patients with chronic rhinosinusitis while its intensity determines the sensation of the intesity of the disorder as a whole.

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Cystic Fibrosis: The Sense of Smell

American Journal of Rhinology and Allergy ◽

10.1177/1945892419870450 ◽

2019 ◽

Vol 34 (1) ◽

pp. 35-42 ◽

Cited By ~ 4

Author(s):

Antonella M. Di Lullo ◽

Paola Iacotucci ◽

Marika Comegna ◽

Felice Amato ◽

Pasquale Dolce ◽

...

Keyword(s):

Quality Of Life ◽

Cystic Fibrosis ◽

Facial Pain ◽

Nasal Polyps ◽

Nasal Congestion ◽

Nasal Discharge ◽

Upper Airways ◽

Multisystem Disease ◽

Mean Values

Background Cystic fibrosis (CF) is a multisystem disease that involves the upper airways with chronic rhinosinusitis (CRS) causing nasal congestion, rhinorrhea, mouth breathing, facial pain, and olfactory dysfunction. Twelve percent to 71% of CF patients report smelling alterations with an impact on nutrition and quality of life. Objectives The goal was to study olfaction performance in CF patients with CRS that worsens quality of life. Methods A total of 121 subjects were enrolled in this study. Seventy-one had CF and underwent ear, nose, and throat evaluation with nasal endoscopy, sinonasal outcome test 22 (SNOT-22), visual analog scale (VAS), and “Sniffin’ Sticks.” Fifty subjects were age-matched with healthy controls. Results All 71 CF patients were affected by CRS; 59 of 71 (83.1%) had CRS without nasal polyps and 12 of 71 (16.9%) had CRS with early nasal polyps. None of the 50 controls had CRS. Total SNOTT-22 mean values in the 71 CF patients were 38.10 ± 21.08 points. If considering only the 59 CF patients without nasal polyps, the SNOTT-22 mean value was 36.76 ± 21.52 points. Moreover, based on the VAS scores, the degree of nasal symptoms was classified as mild for facial pain, smell alteration, nasal discharge, and sneezing and resulted in moderate symptoms for nasal blockage and headache. Among the CF patients, 55 of 71 (76.5%) declared to be normosmic, while the smelling ability assessed by “Sniffin’ Sticks” showed that only 4 of 71 (5.63%) were normosmic, 58 (81.69%) were hyposmic, and 9 (12.68%) were anosmic. In the controls, 41(82%) were normosmic, 9 (18%) were hyposmic, and none were reported to be anosmic ( P < .001). Conclusions We confirm that most CF patients have a relevant olfactory impairment, although only a low percentage declares such alteration. A careful evaluation with simple and rapid tests helps to select the patients who may benefit from specific therapies.

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Correlations between symptoms, nasal endoscopy and computed tomography findings in patients with chronic rhinosinusitis without nasal polyps

Vojnosanitetski pregled ◽

10.2298/vsp171218044s ◽

2020 ◽

Vol 77 (1) ◽

pp. 41-46

Author(s):

Slobodan Savovic ◽

Natasa Dragnic ◽

Vladimir Kljajic ◽

Ljiljana Jovancevic ◽

Maja Buljcik-Cupic ◽

...

Keyword(s):

Chronic Rhinosinusitis ◽

Facial Pain ◽

Nasal Polyps ◽

Nasal Congestion ◽

Endoscopic Examination ◽

Nasal Endoscopy ◽

Nasal Discharge ◽

Strongly Correlated ◽

Moderate Correlation ◽

Severity Of The Disease

Background/Aim. Chronic rhinosinusitis (CRS) is one of the most common chronic conditions that is diagnosed on the basis of the condition symptoms, nasal endoscopy and computed tomograhpy (CT) of the nose and paranasal sinuses. There are two forms of CRS: CRS with nasal polyps (CRSwNP) and CRS without nasal polyps (CRSsNP). The aim of this paper was to determine if there is a correlation between the symptoms, nasal endoscopy and CT in patients with CRSsNP. Methods. The study included 110 patients with CRSsNP. The intensity of the symptoms assessed on the visual analogue scale (VAS) and the condition of nasal mucosa and the presence of nasal secretion was estimated by endoscopic examination of the nose while CT was used to determine the Lund-Mackay (LM) score values. Pearson?s coefficient of correlation was used for statistic data processing. Results. The severity of the disease as a whole (r = 0.509) and nasal discharge (r = 0.562) moderately correlated with CT. Nasal congestion (r = 0.354) and the reduction of loss of smell (r = 0.324) mildly correlated with CT, while facial pain/pressure (r = 0.218) had a very weak correlation with CT. The severity of the disease as a whole (r = 0.717) and nasal discharge (r = 0.821) strongly correlated with nasal endoscopy. Nasal congestion (r = 0.525) had a moderate correlation with nasal endoscopy while facial pain/pressure (r = 0.345) and the reduction of the loss of smell (r= 0.394) had a mild correlation with nasal endoscopy. A moderate correlation was found between nasal endoscopy and CT (r = 0.630). Conclusion. The severity of the disease as a whole and nasal discharge have more significant correlations both with nasal endoscopy and CT in relation to the correlations between other symptoms and nasal endoscopy, as well as CT. More significant correlations between the symptoms and nasal endoscopy in relation to the correlations between the symptoms and CT and the existence of a moderate correlation between nasal endoscopy and CT, enable a lesser use of CT diagnostics and only in precisely defined situatiations.

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Effect of functional endoscopic sinus surgery on the symptom profile in chronic rhinosinusitis cases

International Journal of Otorhinolaryngology and Head and Neck Surgery ◽

10.18203/issn.2454-5929.ijohns20200154 ◽

2020 ◽

Vol 6 (2) ◽

pp. 375

Author(s):

G. Syam Manohar ◽

Khan Majid Jabbar

Keyword(s):

Quality Of Life ◽

Chronic Rhinosinusitis ◽

Nasal Obstruction ◽

Endoscopic Sinus Surgery ◽

Facial Pain ◽

Functional Endoscopic Sinus Surgery ◽

Sinus Surgery ◽

Nasal Discharge ◽

Symptom Profile

Background: Chronic rhinosinusitis (CRS) is a common chronic disease, that have considerable impact on quality of life, functional and emotional impairments of affected beings. Post-surgical improvement of quality of life indicates the surgical success. Functional endoscopic sinus surgery (FESS) is the dominating surgical procedure for CRS. This study was designed to assess the symptom profile of patient before and after surgery and the complications after FESS in the post-operative period.Methods: A total of 50 cases attending ENT outpatient department with clinical features and investigations suggestive of chronic sinusitis with infective pathology were randomly considered for this study. Cases were assessed for CRS symptoms pre and post operatively using grading symptoms. Results: Common major symptom was nasal obstruction (93.3%, N=28) followed by post nasal drip (83.33%, N=25), purulent nasal discharge (76.66%, N=23), facial pain/pressure (66.66%, N=20) and hyposmia (60%, N=18). None of the patients reported fever and facial congestion or fullness. Post operatively, cases with nasal obstruction (92.8%), purulent nasal discharge (86.9%), facial pain or pressure (85%), headache (81.8%), post nasal drip (84%), ear pain or fullness or pressure (92.8%) and hyposmia (61.1%) showed improvement after FESS at the end of three follow-up.Conclusions: The most common symptom pre operatively was nasal obstruction which also responded best to FESS, along with all the other minor symptoms including headache. The results of this study confirm that FESS is an excellent method of treatment in patients with CRS refractory to medical treatment.

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Long-Term Clinical Follow-Up of Patients With Chronic Rhinosinusitis

Annals of Otology Rhinology & Laryngology ◽

10.1177/0003489420962822 ◽

2020 ◽

pp. 000348942096282

Author(s):

Ulrica Thunberg ◽

Amanj Saber ◽

Bo Söderquist ◽

Svante Hugosson

Keyword(s):

Quality Of Life ◽

Chronic Rhinosinusitis ◽

Nasal Polyposis ◽

Nasal Congestion ◽

Symptom Relief ◽

Nasal Discharge ◽

Long Term Follow Up

Objective: This study comprised a long-term follow-up of a cohort of patients with chronic rhinosinusitis (CRS) regarding clinical features and symptomatology. Methods: Data from 42 patients with CRS were available from a previous study. Forty of these patients were alive and were contacted for inclusion after approximately 10 years. Patients completed a questionnaire about disease and symptoms, and underwent a clinical examination. Results: Thirty-four patients (85%) responded and could be included and evaluated. For the participants in this follow-up study median length of time between initial inclusion (C1) and follow-up (C2) was 11 years (range: 8-15). In some patients the CRS shifted phenotype over time, from CRS with nasal polyposis to CRS without nasal polyposis or vice versa. The median total visual analogue score for combined sinonasal symptoms for all patients was statistically significantly reduced at follow-up. For individual patients, scores for nasal congestion, nasal discharge, facial pressure, and hyposmia were also statistically significantly reduced. The most frequently reported symptom-relieving treatments were nasal steroids and saline rinsing of the nose. Self-reported general quality of life was statistically significantly improved at C2 compared to C1. Conclusion: At long-term follow-up, symptoms were generally reduced and patients reported an improved quality of life. Patients can be given hope for eventual symptom relief. CRS is a chronic condition that seems to harbor the ability to alter its phenotype after several years. Topical corticosteroids and saline rinsing of the nose should be emphasized, since patients consider these treatments to be of high value.

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CLINICAL PROFILE OF CHRONIC RHINOSINUSITIS: A STUDY IN CENTRAL INDIA

10.36106/paripex/1809951 ◽

2021 ◽

pp. 104-106

Author(s):

Tanvi Rekhade ◽

A.Z. Nitnaware ◽

Seema Patel ◽

R.T. Pawar ◽

Ashish Keche

Keyword(s):

Quality Of Life ◽

Chronic Rhinosinusitis ◽

Nasal Septum ◽

Nasal Polyps ◽

Central India ◽

Nasal Discharge ◽

Deviated Nasal Septum ◽

Northern India ◽

Causative Factors

Chronic Rhinosinusitis (CRS) has heavy implications on the quality of life and has a prevalence of about 46.1 % in northern India with similar pattern across the country.This research has been undertaken to study the presentation and causative factors for CRS in central India. Data of 100 patients diagnosed as CRS was studied. Patients presented with nasal obstruction and nasal discharge at large. Nasal polyps were seen in 37% cases. The most common associated etiopathological factor was anatomical obstruction due to deviated nasal septum.

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Chronic rhinosinusitis

InnovAiT Education and inspiration for general practice ◽

10.1177/1755738019837295 ◽

2019 ◽

Vol 13 (4) ◽

pp. 199-206

Author(s):

Emma Dickson ◽

Claire Hopkins

Keyword(s):

Chronic Rhinosinusitis ◽

Nasal Polyposis ◽

Adult Population ◽

Economic Cost ◽

Saline Irrigation ◽

Persistent Symptoms ◽

Nose And Paranasal Sinuses ◽

The Uk ◽

Aids Diagnosis

Chronic rhinosinusitis affects 10.9% of the UK adult population, affecting quality of life and with significant economic cost. The aetiology is unknown, and diagnosis can present challenges. It is characterised by inflammation of the nose and paranasal sinuses that leads to nasal obstruction, discharge, facial pain or pressure and loss of smell, persisting for more than 3 months. Nasal cavity examination aids diagnosis. It is subdivided into chronic rhinosinusitis with and without nasal polyposis. Nasal corticosteroids and saline irrigation make up current baseline management in primary care, with referral to ENT recommended for those with persistent symptoms. Physicians should be alert to persistent unilateral symptoms and the risk of sino-nasal tumours.

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Chronic rhinosinusitis assessment using the Adelaide Disease Severity Score

The Journal of Laryngology & Otology ◽

10.1017/s0022215113000558 ◽

2013 ◽

Vol 127 (S2) ◽

pp. S24-S28 ◽

Cited By ~ 10

Author(s):

Y Naidoo ◽

N Tan ◽

D Singhal ◽

P J Wormald

Keyword(s):

Quality Of Life ◽

Chronic Rhinosinusitis ◽

Disease Severity ◽

Severity Score ◽

Facial Pain ◽

The Other ◽

Sinus Surgery ◽

Disease Severity Score ◽

Spearman Coefficient

AbstractAim:This study aimed to validate the use of the Adelaide Disease Severity Score for the assessment of chronic rhinosinusitis.Study design:A prospective cohort study supplying level 2b evidence.Methods:Forty-eight patients, scheduled for endoscopic sinus surgery for failed management of chronic rhinosinusitis, completed the Sino-Nasal Outcome Test 22 and the Adelaide Disease Severity Score tool (the latter assessing symptoms (i.e. nasal obstruction, rhinorrhoea, post-nasal drip, headache or facial pain, and olfaction) and quality of life). Lund–Mackay computed tomography scores and Lund–Kennedy endoscopic scores were also recorded. The Adelaide Disease Severity Score results were then compared with those of the other three tools to assess correlation.Results:Mean scores (95 per cent confidence intervals) were 22.31 (21.47–24.15) for the Adelaide Disease Severity Score and 30.6 (27.15–34.05) for the Sino-Nasal Outcome Test 22; there was a statistically significant correlation (Spearman coefficient = 0.45; p = 0.0015). A statistically significant correlation was also noted with the Lund–Mackay score (p = 0.04) and with the Lund–Kennedy score (p = 0.03).Conclusion:The Adelaide Disease Severity Score is a simple, valid tool for clinical assessment of chronic rhinosinusitis, which correlates well with the Sino-Nasal Outcome Test 22, Lund–Mackay and Lund–Kennedy tools.

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GAMBARAN DERAJAT KEPARAHAN GEJALA PASIEN RINOSINUSITIS KRONIK DI RSUD DR. SOETOMO SURABAYA

Care Jurnal Ilmiah Ilmu Kesehatan ◽

10.33366/jc.v8i2.1666 ◽

2020 ◽

Vol 8 (2) ◽

pp. 235

Author(s):

Anggita Putri Samara ◽

Budi Sutikno ◽

Reny I’tishom

Keyword(s):

Risk Factor ◽

Observational Study ◽

Medical Record ◽

Nasal Obstruction ◽

Facial Pain ◽

Nasal Congestion ◽

The Other ◽

Nasal Discharge ◽

Analog Scale ◽

Nasal Inflammation

Chronic rhinosinusitis (CRS) is a sinus paranasal and nasal inflammation marked with two or more symptoms, nasal congestion or nasal discharge and the other symptom like facial pain and reduced smell may present. This symptom occur >12 weeks. One of the parameter for symptom’s severity assessmentis using Visual Analog Scale (VAS) that can be classified as mild (0-3), moderate (4-7), dan severe (8-10). This study was a observational study by assessing patient’s medical record at SMF THT-KL RSUD Dr. Soetomo and analyzed descriptively. 43 patients were enrolled to study (28 male and 15 female), most of them were between age 36-45 years old (25,58%). Most of the patient’s symptom’s severity in general, nasal obstruction, nasal discharge, facial pain, and reduced smell were moderate (65,11%), moderate (58,13%), mild (41,86%), mild (58,13%), mild (62,79%) respectively. Most of the patients had risk factor (62,79%), and the most of the patient’s risk factor were allergy. Most of the CRS patients in this study were male, 36-45 years old, with the general symptom’s severity moderate, moderate nasal obstruction, mild nasal discharge, mild facial pain, mild reduced smell, and had allergy.

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Clinical Presentations of Patients with Chronic Rhinosinusitis

Journal of Pharmaceutical Research International ◽

10.9734/jpri/2021/v33i46a32864 ◽

2021 ◽

pp. 257-263

Author(s):

Ahmad Mujahed Abdulqader Mousa ◽

Zadorozhna Anna ◽

Dieieva Julia ◽

Tereshchenko Zhanna ◽

Konovalov Serhii

Keyword(s):

Infectious Disease ◽

Chronic Rhinosinusitis ◽

Clinical Features ◽

Paranasal Sinuses ◽

Nasal Congestion ◽

Nasal Discharge ◽

Impaired Ability ◽

Clinical Presentations ◽

The Face ◽

Anterior Posterior

Purpose of Review: Chronic rhinosinusitis (CRS) is denoted as the symptomatic inflammations of sin nasal mucosa persists for ≥12 weeks. The purpose of this study was to review the recent literatures for digging out a clear concept on the clinical presentations of patients with chronic rhinosinusitis and assess the potentialities of the features. Recent Findings: According to the findings, descriptions and discussions of several recent studies it was observed that, a package of clinical features and presentations are associated with chronic rhinosinusitis. Some are major and some are minor potentials. The frequencies and severities of symptoms and features are directly dependent on the duration of that disease. Summary: Basically, rhinosinusitis or CRS is an inflammatory and infectious disease which affects the nasal cavities as well as the paranasal sinuses of patients. Rhinosinusitis with polyps is more common in male than that in female. There are many possible clinical features of CRS. But as per the frequencies, duration and effects nasal congestion, nasal discharge (Anterior/posterior nasal drip), pain/pressure on the face, impaired ability to smell (Hyposmia/anosmia), dizziness, fever and cough are the most common clinical features of chronic rhinosinusitis.

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Experience with the xylocaine test as a prognostic aid for surgery in Sluder's neuralgia

The Journal of Laryngology & Otology ◽

10.1017/s0022215100129676 ◽

1995 ◽

Vol 109 (3) ◽

pp. 193-195 ◽

Cited By ~ 8

Author(s):

Syed Akhtar Kamal

Keyword(s):

Medical Treatment ◽

Chronic Rhinosinusitis ◽

Surgical Procedures ◽

Paranasal Sinuses ◽

Facial Pain ◽

Common Symptom ◽

Septal Surgery ◽

Nose And Paranasal Sinuses ◽

Overt Disease

AbstractFacial pain is a common symptom. Patients with this symptom without any overt disease of nose and paranasal sinuses are often diagnosed as having chronic rhinosinusitis. Thirty-six cases were seen and treated surgically by middle turbinectomy or septal surgery in this series. The xylocaine (10 per cent) test seemed to be a good prognostic aid for the surgical procedures. Medical treatment did not seem to relieve the symptoms. Larger series with control trials are recommended in order to establish this practice.

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