scholarly journals Changes in the oral cavity caused by scurvy

2003 ◽  
Vol 60 (6) ◽  
pp. 753-756 ◽  
Author(s):  
Dragana Dakovic ◽  
Besir Ljuskovic ◽  
Ivan Mileusnic ◽  
Vesna Tepsic
Keyword(s):  
Vitamin C ◽  
Oral Cavity ◽  
Rare Disease ◽  
Clinical Examination ◽  
Psychiatric Patient ◽  
Clinical Signs ◽  
Complete Recovery ◽  
Vitamin C Deficiency ◽  
Plaque Control ◽  
Prompt Diagnosis

This report presents a case of a psychiatric patient with scurvy. Upon the clinical examination of the oral cavity, dry and pale lips were noted. Gingiva was highly edematous, soft, purple blue with ulcerated margins. Bleeding was noted upon slightest provocation. Teeth were also affected by the vitamin C deficiency with multiple caries. The patient was asthenic and adynamic. Petechial bleeding and hematomas were present on the skin of extremities. Therapy consisted of rehydration and vitamin C compensation - 2 g daily i.v. during 10 days period, and 1.5 g daily orally during the following 2 months. The patient maintained only partial plaque control, and complete recovery of the oral cavity was not established because the patient didn?t comply. Concerning that scurvy is a rare disease nowadays, it is very important to recognize its clinical signs, and to establish a valid and prompt diagnosis, because, when untreated, scurvy can have severe consequences on the entire organism.

Disturbo della condotta alimentare, ecchimosi e carenza di vitamina C

2021 ◽  
Vol 24 (9) ◽  
pp. 273-276
Author(s):  
Anna Attico ◽  
Alessandra Iacono ◽  
Loretta Biserna ◽  
Sara Brandolini ◽  
Federico Marchetti
Keyword(s):  
Eating Disorder ◽  
Vitamin C ◽  
Rare Disease ◽  
Eating Habits ◽  
Coagulation Disorders ◽  
Vitamin C Deficiency ◽  
History Of ◽  
Laboratory Investigations

The paper presents the case of a 16-year-old girl with a 6-month history of eating disorder, restrictive subtype and diffuse ecchymosis. Anamnestic history and laboratory investigations allowed excluding coagulation disorders and making the diagnosis of vitamin C deficiency. Vitamin C deficiency is a rare disease but still sporadically described in children with unusual eating habits.

Some Observations on Vitamin C Deficiency in Acute Mental Disorder

1938 ◽  
Vol 84 (352) ◽  
pp. 788-800 ◽  
Author(s):  
F. T. Thorpe
Keyword(s):  
Vitamin C ◽  
Mental Disorder ◽  
Clinical Signs ◽  
Psychotic Patient ◽  
Vitamin C Deficiency ◽  
Mental Confusion

It is well known that gross impairment of nutrition is a not infrequent finding in the newly-admitted psychotic patient. Some of these cases present a state of mental confusion which is directly attributable to a condition of semi-starvation brought about by personal neglect and refusal of food. Obvious clinical signs of malnutrition are present, such as anorexia, emaciation, coated tongue, constipation, and ketonuria. Rapid mental improvement frequently occurs as a result of a liberal diet and relief of gastro-intestinal stasis. But it is equally important to recognize the mild and less obvious forms of malnutrition.

scholarly journals Validation of a clinical examination to differentiate a cervicogenic source of headache: a diagnostic prediction model using controlled diagnostic blocks

BMJ Open ◽  
2020 ◽  
Vol 10 (5) ◽  
pp. e035245 ◽  
Author(s):  
Scott L Getsoian ◽  
Surendra M Gulati ◽  
Ikenna Okpareke ◽  
Robert J Nee ◽  
Gwendolen A Jull
Keyword(s):  
Neck Pain ◽  
Clinical Examination ◽  
Model Building ◽  
Clinical Signs ◽  
Cervicogenic Headache ◽  
Tension Type Headache ◽  
Local Source ◽  
Diagnostic Model ◽  
Convenience Sample ◽  
Headache And Neck Pain

ObjectivesNeck pain commonly accompanies recurrent headaches such as migraine, tension-type and cervicogenic headache. Neck pain may be part of the headache symptom complex or a local source. Patients commonly seek neck treatment to alleviate headache, but this is only indicated when cervical musculoskeletal dysfunction is the source of pain. Clinical presentation of reduced cervical extension, painful cervical joint dysfunction and impaired muscle function collectively has been shown to identify cervicogenic headache among patients with recurrent headaches. The pattern’s validity has not been tested against the ‘gold standard’ of controlled diagnostic blocks. This study assessed the validity of this pattern of cervical musculoskeletal signs to identify a cervical source of headache and neck pain, against controlled diagnostic blocks, in patients with headache and neck pain.DesignProspective concurrent validity study that employed a diagnostic model building approach to analysis.SettingHospital-based multidisciplinary outpatient clinic in Joliet, Illinois.ParticipantsA convenience sample of participants who presented to a headache clinic with recurrent headaches associated with neck pain. Sixty participants were enrolled and thirty were included in the analysis.Outcome measuresParticipants underwent a clinical examination consisting of relevant tests of cervical musculoskeletal dysfunction. Controlled diagnostic blocks of C2/C3–C3/C4 established a cervical source of neck pain. Penalised logistic regression identified clinical signs to be included in a diagnostic model that best predicted participants’ responses to diagnostic blocks.ResultsTen of thirty participants responded to diagnostic blocks. The full pattern of cervical musculoskeletal signs best predicted participants’ responses (expected prediction error = 0.57) and accounted for 65% of the variance in responses.ConclusionsThis study confirmed the validity of the musculoskeletal pattern to identify a cervical source of headache and neck pain. Adopting this criterion pattern may strengthen cervicogenic headache diagnosis and inform differential diagnosis of neck pain accompanying migraine and tension-type headache.

scholarly journals Vitamin C Deficiency in Inflammatory Bowel Disease: The Forgotten Micronutrient

2021 ◽  
Author(s):  
Katie A Dunleavy ◽  
Ryan C Ungaro ◽  
Laura Manning ◽  
Stephanie Gold ◽  
Joshua Novak ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Vitamin C ◽  
Bowel Disease ◽  
Fruits And Vegetables ◽  
Nutritional Assessment ◽  
Care Center ◽  
Tertiary Care ◽  
Case Series ◽  
Vitamin C Deficiency ◽  
Inflammatory Bowel

Abstract Background Micronutrient deficiencies are common in patients with inflammatory bowel disease (IBD). To date, the literature has focused on vitamin D, vitamin B12, and iron deficiencies. Methods We report a case series of 20 patients with IBD and vitamin C deficiency treated at a single tertiary care center. Results Sixteen (80%) patients had symptoms of clinical scurvy, including arthralgia, dry brittle hair, pigmented rash, gingivitis, easy bruising and/or brittle nails. Eighteen patients underwent a nutritional assessment, 10 (56%) patients reported complete avoidance of fruits and vegetables, and 3 (17%) reported reduced intake of fruits and vegetables. Conclusions Vitamin C deficiency should be considered in IBD patients, particularly those with reduced fruit/vegetable intake, as it can lead to significant signs and symptoms.

scholarly journals Vitamin C in Human Health and Disease

Nutrients ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 1595
Author(s):  
Dariusz Nowak
Keyword(s):  
Eighteenth Century ◽  
Vitamin C ◽  
Human Health ◽  
Citrus Fruit ◽  
Ancient Egypt ◽  
Vitamin Supplement ◽  
Vitamin C Deficiency ◽  
Health And Disease

Although the symptoms related to vitamin C deficiency were known in ancient Egypt and eighteenth century Scottish surgeon James Lind found that scurvy (a disease resulting from insufficient dietary ingestion of vitamin C) could be effectively treated with citrus fruit, this vitamin was discovered only in the year 1912 and then after 21 years it was chemically synthetized and introduced to the market as the first vitamin supplement [...]

The multifactorial aetiology of gingival overgrowth: a case report illustrating diagnosis and management

Dental Update ◽  
2019 ◽  
Vol 46 (7) ◽  
pp. 662-671
Author(s):  
Rachael Y Jablonski ◽  
Bethany Rushworth ◽  
Kathryn A Durey
Keyword(s):  
Case Report ◽  
Renal Transplantation ◽  
Vitamin C ◽  
Oral Hygiene ◽  
Patient Engagement ◽  
Surgical Intervention ◽  
Gingival Overgrowth ◽  
Vitamin C Deficiency ◽  
Specialist Services ◽  
Detailed Assessment

Gingival overgrowth is the enlargement of gingival tissues and has various underlying aetiological factors. This case report highlights the multifactorial aetiology of gingival overgrowth for a patient who was prescribed an immunosuppressive strategy following renal transplantation, had poor levels of oral hygiene and a diet deficient in fruit and vegetables. The report highlights the importance of a detailed assessment to identify all underlying factors and demonstrates how a referral to the specialist services for gingival overgrowth led to a diagnosis of vitamin C deficiency. It also illustrates how both patient engagement and a conservative cause-related therapy can achieve a satisfactory resolution without any surgical intervention. CPD/Clinical Relevance: This case report highlights the importance of a detailed assessment to diagnose all relevant underlying aetiological factors involved in the development of gingival overgrowth. It also illustrates how both patient engagement and a conservative cause-related therapy can achieve a satisfactory resolution of gingival overgrowth without any surgical intervention.

Is sudden death with vitamin C deficiency caused by lack of carnitine?

2006 ◽  
Vol 13 (1) ◽  
pp. 26-29 ◽  
Author(s):  
Maya Okamoto ◽  
Yasuhiro Ueno
Keyword(s):  
Sudden Death ◽  
Vitamin C ◽  
Vitamin C Deficiency

scholarly journals Early Life Vitamin C Deficiency Does Not Alter Morphology of Hippocampal CA1 Pyramidal Neurons or Markers of Synaptic Plasticity in a Guinea Pig Model

Nutrients ◽  
2018 ◽  
Vol 10 (6) ◽  
pp. 749 ◽  
Author(s):  
Stine Hansen ◽  
Jane Jørgensen ◽  
Jens Nyengaard ◽  
Jens Lykkesfeldt ◽  
Pernille Tveden-Nyborg
Keyword(s):  
Synaptic Plasticity ◽  
Vitamin C ◽  
Guinea Pig ◽  
Early Life ◽  
Pyramidal Neurons ◽  
Pig Model ◽  
Vitamin C Deficiency ◽  
Ca1 Pyramidal Neurons ◽  
Hippocampal Ca1 ◽  
Guinea Pig Model
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