scholarly journals Dual-Contrast Cellular Magnetic Resonance Imaging

2009 ◽  
Vol 8 (5) ◽  
pp. 7290.2009.00024 ◽  
Author(s):  
Rohan Dharmakumar ◽  
Zhouli Zhang ◽  
Ioannis Koktzoglou ◽  
Sotirios A. Tsaftaris ◽  
Debiao Li
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Three Dimensional ◽  
Negative Contrast ◽  
Cellular Imaging ◽  
Resonance Imaging ◽  
Specificity And Sensitivity ◽  
Contrast Magnetic Resonance ◽  
Imaging Research ◽  
Magnetic Resonance Imaging Mri

Negative contrast magnetic resonance imaging (MRI) methods using magnetic susceptibility shifting agents have become one of the most important approaches in cellular imaging research. However, visualizing and tracking labeled cells on the basis of negative contrast is often met with limited specificity and sensitivity. Here we report on a MRI method for cellular imaging that generates a new contrast with a distinct topology for identifying labeled cells that has the potential to significantly improve both the sensitivity and the specificity. Specifically, we show that low flip-angle steady-state free precession MRI can be used to generate fast three-dimensional images of tissue that can be rapidly processed to generate quantitative metrics enabling color overlays indicative of regions containing labeled cells. The technique substantially improves the ability of MRI for detecting labeled cells by overcoming the fundamental limits that currently plague negative contrast methods.

Computed Tomography and Magnetic Resonance Imaging-aided Diagnosis of Primary Essential Cutis Verticis Gyrata: A Case Report with 5-year Follow-up and Review of the Literature

2019 ◽  
Vol 15 (9) ◽  
pp. 906-910
Author(s):  
Hongzhang Zhu ◽  
Shi-Ting Feng ◽  
Xingqi Zhang ◽  
Zunfu Ke ◽  
Ruixi Zeng ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Three Dimensional ◽  
Stable Condition ◽  
Resonance Imaging ◽  
Mri Findings ◽  
Cutis Verticis Gyrata ◽  
Essential Form ◽  
History Of ◽  
Magnetic Resonance Imaging Mri

Background: Cutis Verticis Gyrata (CVG) is a rare skin disease caused by overgrowth of the scalp, presenting as cerebriform folds and wrinkles. CVG can be classified into two forms: primary (essential and non-essential) and secondary. The primary non-essential form is often associated with neurological and ophthalmological abnormalities, while the primary essential form occurs without associated comorbidities. Discussion: We report on a rare case of primary essential CVG with a 4-year history of normal-colored scalp skin mass in the parietal-occipital region without symptom in a 34-year-old male patient, retrospectively summarizing his pathological and Computer Tomography (CT) and magnetic resonance imaging (MRI) findings. The major clinical observations on the CT and MR sectional images include a thickened dermis and excessive growth of the scalp, forming the characteristic scalp folds. With the help of CT and MRI Three-dimensional (3D) reconstruction techniques, the characteristic skin changes could be displayed intuitively, providing more evidence for a diagnosis of CVG. At the 5-year followup, there were no obvious changes in the lesion. Conclusion: Based on our observations, we propose that not all patients with primary essential CVG need surgical intervention, and continuous clinical observation should be an appropriate therapy for those in stable condition.

In Vivo Tracking of the Human Patella Using Cine Phase Contrast Magnetic Resonance Imaging

1999 ◽  
Vol 121 (6) ◽  
pp. 650-656 ◽  
Author(s):  
F. T. Sheehan ◽  
F. E. Zajac ◽  
J. E. Drace
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Knee Joint ◽  
Phase Contrast ◽  
Three Dimensional ◽  
Resonance Imaging ◽  
Contrast Magnetic Resonance ◽  
Knee Joint Kinematics ◽  
Cine Phase Contrast

Improper patellar tracking is often considered to be the cause of patellar-femoral pain. Unfortunately, our knowledge of patellar-femoral-tibial (knee) joint kinematics is severely limited due to a lack of three-dimensional, noninvasive, in vivo measurement techniques. This study presents the first large-scale, dynamic, three-dimensional, noninvasive, in vivo study of nonimpaired knee joint kinematics during volitional leg extensions. Cine-phase contrast magnetic resonance imaging was used to measure the velocity profiles of the patella, femur, and tibia in 18 unimpaired knees during leg extensions, resisted by a 34 N weight. Bone displacements were calculated through integration and then converted into three-dimensional orientation angles. We found that the patella displaced laterally, superiorly, and anteriorly as the knee extended. Further, patellar flexion lagged knee flexion, patellar tilt was variable, and patellar rotation was fairly constant throughout extension.

scholarly journals Applicability of Magnetic Resonance Imaging in the Assessment of Fetal Urinary Tract Malformations

2019 ◽  
Vol 70 (1) ◽  
pp. 83-95 ◽  
Author(s):  
Tatiana Mendonça Fazecas ◽  
Edward Araujo Júnior ◽  
Heron Werner ◽  
Pedro Daltro ◽  
Alberto Borges Peixoto ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Urinary Tract ◽  
Magnetic Resonance ◽  
Three Dimensional ◽  
Surface Coil ◽  
Resonance Imaging ◽  
Magnetic Resonance Imaging Mri ◽  
Urinary Tract Malformations ◽  
Weighted Sequences ◽  
Urinary Tract Anomalies

Objective To assess the applicability of magnetic resonance imaging (MRI) to complement ultrasound in the diagnosis of fetal urinary tract anomalies. Methods This was a retrospective cohort study that included 41 women between 19 weeks and 37 weeks and 6 days of gestation carrying fetuses with malformations of the urinary tract which were initially diagnosed by ultrasound and then referred for MRI. In all cases, the diagnosis was confirmed after birth either through imaging or autopsy. A surface coil was positioned over the abdomen and T2-weighted sequences were obtained in the axial, coronal, and sagittal planes; T1 in at least one plane; and three-dimensional (3-D) TRUFI in fetuses with dilatation of the urinary tract. Results Mean gestational age at the time of MRI examination was 28.21 weeks. The rapid T2 sequences allowed all the anomalies of the fetal urinary tract to be assessed, whereas 3-D TRUFI sequencing proved very useful in evaluating anomalies involving dilatation of the urinary tract. The signs of pulmonary hypoplasia characterized by hypointense signal in the T2-weighted sequences were identified in 13 of the 41 fetuses. Conclusion MRI confirmed and added information to the ultrasound regarding fetal urinary tract anomalies, as well as information related to the other associated malformations, their progress in the prenatal period, and possible postnatal prognosis.

scholarly journals Magnetic Resonance Imaging of the Anal Region: Clinical Applications

2020 ◽  
Vol 10 ◽  
pp. 76
Author(s):  
Giuseppe Cicero ◽  
Giorgio Ascenti ◽  
Alfredo Blandino ◽  
Socrate Pallio ◽  
Claudia Abate ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Anal Canal ◽  
Three Dimensional ◽  
Resonance Imaging ◽  
Pictorial Review ◽  
Clinical Scenarios ◽  
Mri Protocol ◽  
Magnetic Resonance Imaging Mri ◽  
Dedicated Mri

Over the past years, magnetic resonance imaging (MRI) has become a cornerstone in evaluating anal canal and adjacent tissues due to its safeness, the three-dimensional and comprehensive approach, and the high soft-tissue resolution. Several diseases arising in the anal canal can be assessed through MRI performance, including congenital conditions, benign pathologies, and malignancies. Good knowledge of the normal anatomy and MRI technical protocols is, therefore, mandatory for appropriate anal pathology evaluation. Radiologists and clinicians should be familiar with the different clinical scenarios and the anatomy of the structures involved. This pictorial review presents an overview of the diseases affecting the anal canal and the surrounding structures evaluated with dedicated MRI protocol.

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