scholarly journals Stability of orthodontic treatment outcomes after 1-year treatment with the eruption guidance appliance in the early mixed dentition: A follow-up study

2018 ◽  
Vol 89 (2) ◽  
pp. 206-213 ◽  
Author(s):  
Rita Myrlund ◽  
Katri Keski-Nisula ◽  
Heidi Kerosuo
Keyword(s):  
Orthodontic Treatment ◽  
Permanent Dentition ◽  
Mixed Dentition ◽  
Retention Period ◽  
Anterior Crowding ◽  
Follow Up Study ◽  
Early Correction ◽  
Group 2 ◽  
Group 1

ABSTRACT Objectives: To investigate occlusal stability from the early mixed to the permanent dentition in children after early treatment with the eruption guidance appliance (EGA). Materials and Methods: Of 46 participants who received 1-year early EGA treatment, 35 attended a follow-up examination at age 12. Group 1 (n = 21) started their EGA treatment at mean age 7.7 years, and group 2 at 9.1 years. Following 1-year treatment, the EGA was used as a retainer. Changes in overjet, overbite, sagittal molar relationship, and anterior crowding were measured on casts obtained before EGA treatment, after EGA treatment, and at follow-up to evaluate occlusal stability. Results: Mean overjet, overbite, sagittal molar relation, and mandibular crowding improved significantly during the study period. Participants with good compliance during the retention period had significantly smaller overjet and overbite values than those with poor compliance. Conclusions: Early correction of increased overjet, overbite, and class II molar relation with the EGA is maintainable and can also be effective in the permanent dentition, provided the EGA is worn regularly as a retainer.

Results of a follow-up study of occlusion status in Ukrainian schoolchildren

2016 ◽  
Vol 69 (6) ◽  
pp. 725-728 ◽  
Author(s):  
Maryna Ivanivna Dmytrenko ◽  
Oleh Nesterenko
Keyword(s):  
Permanent Dentition ◽  
Mixed Dentition ◽  
Follow Up Study ◽  
Early Stages ◽  
Significant Difference ◽  
Different Types ◽  
Dental Crowding

Introduction. Dental crowding complicates sagittal, vertical and transversal types of malocclusion and it is accompanied by aesthetic, functional and morphological disorders even on the early stages of occlusion formation. Aim of the study. The aim of the study is to carry out follow up study of occlusion state of one schoolchildren group in period from temporary to permanent dentition in order to determine in age aspect frequency and mechanism of development of malocclusions, complicated by dental crowding. Materials and methods. Follow up study of occlusion state in 434 schoolchildren of Poltava aged from 6 to 11 years old (girls – 246 (56,68%), boys – 188 (43,32%) was performed during six years. Results. The follow-up of one contingent of children confirms high (79,96%) prevalence of malocclusion in mixed dentition, which increases during permanent dentition to an average of 84,33%, that is to 4,37%. Orthodontic pathology in permanent dentition becomes more expressed and severe. Malocclusions complicated by dental crowding are the most widespread types, their frequency doubles within six years, mixed dentition – 33,54% permanent dentition – 68,67%. (Rχ2 lower than 0,05). There is no statistically significant difference in factors of dental crowding presence in different types of malocclusion (Рχ2> 0,05). Conclusions. Frequency of the sagittal, vertical and transversal forms of malocclusion complicated by dental crowding was 33.54% in mixed dentition , and in six years it increased by 68,67% in permanent dentition.

scholarly journals Soluble Intercellular Adhesion Molecule-1 (sICAM-1) Concentrations in Graves’ Disease Patients Followed Up for Development of Ophthalmopathy

1998 ◽  
Vol 83 (4) ◽  
pp. 1222-1225
Author(s):  
A. De Bellis ◽  
S. Di Martino ◽  
F. Fiordelisi ◽  
V. I. Muccitelli ◽  
A. A. Sinisi ◽  
...  
Keyword(s):  
Adhesion Molecule ◽  
Serum Levels ◽  
Intercellular Adhesion Molecule ◽  
Graves Disease ◽  
Intercellular Adhesion Molecule 1 ◽  
Follow Up Study ◽  
Soluble Intercellular Adhesion Molecule ◽  
Group 2 ◽  
Group 1

It is commonly recognized that a few patients with Graves’ disease (GD) develop an overt ophthalmopathy, although most of them show subclinical extraocular muscle enlargement by appropriate imaging techniques. At present, it is not possible to identify the subgroup of GD patients with subclinical retroorbital connective involvement. Recently, it has been shown that increase of soluble intercellular adhesion molecule-1 (sICAM-1) serum levels is correlated to clinical activity score in active Graves’ ophthalmopathy (GO) patients with or without hyperthyroidism, suggesting that sICAM-1 serum values could reflect the degree of ocular inflammatory activity. The aim of this longitudinal study was to evaluate sICAM-1 serum levels in GD patients without clinical ophthalmopathy and to assess their possible relationship with occurrence of GO. We measured sICAM-1 serum levels in 103 initially hyperthyroid GD patients without clinical ophthalmopathy and in 100 healthy subjects. All patients were treated with methimazole for 2 yr. Sera were collected from all patients before treatment and then monthly for the first 6 months of therapy, every 2 months in the following 6 months, and finally at the end of the follow-up study. Patients developing GO were excluded from the follow-up at the onset of ophthalmopathy. During the follow-up 17 GD patients (16.5%, group 1) developed overt eye involvement (14 as active inflammatory ophthalmopathy and 3 as ophthalmopathy without clinical retroorbital connective inflammation) and 86 (83.5%, group 2) did not. At start of the study, the mean of sICAM-1 serum concentrations did not differ significantly between the 2 groups, but it was significantly higher than in controls in both groups. No significant correlation between serum sICAM-1 concentrations and free thyroid hormone levels was found in the 2 groups of patients. During the follow-up study, a further increase of sICAM-1 serum levels was observed in 12 of the 14 patients (85.7%) of group 1 who developed active inflammatory ophthalmopathy not only at the onset but also before clinical GO appearance. On the contrary, the 3 patients of group 1 that developed ophthalmopathy without clinical retroorbital inflammation did not show any further increase of sICAM-1 levels at every time of follow-up in comparison with the starting values, even if their sICAM-1 levels were always higher than in normal controls. Finally, group 2 patients showed significantly decreased sICAM-1 levels throughout the follow-up period when compared with the starting values, although they were still significantly higher than in controls. These results indicate that a further increase of sICAM-1 serum levels before the onset of clinical ophthalmopathy may be a marker of subclinical retroorbital connective inflammation in GD patients. Therefore, our study suggests that serial determinations of sICAM-1 serum levels could help to identify and trace at the right time those GD patients prone to developing active inflammatory ophthalmopathy.

scholarly journals Stability in Dental Changes in RME and SARME: A 2-Year Follow-up

2009 ◽  
Vol 79 (2) ◽  
pp. 207-213 ◽  
Author(s):  
Oral Sokucu ◽  
H. Huseyin Kosger ◽  
A. Altug Bıcakci ◽  
Hasan Babacan
Keyword(s):  
Orthodontic Treatment ◽  
Rapid Maxillary Expansion ◽  
Study Group ◽  
Maxillary Expansion ◽  
Patient Groups ◽  
Group 2 ◽  
Maxillary Arch ◽  
Group 1 ◽  
Dental Casts

Abstract Objective: To compare the effects of rapid maxillary expansion (RME) and surgically assisted rapid maxillary expansion (SARME) on dentoalveolar structures following orthodontic treatment, as well as stability at 2-year follow-up. Materials and Methods: Two groups of subjects were used in the study. Group 1 consisted of 14 subjects (mean age, 12.7 ± 1.4 years) who were treated with RME, and Group 2 consisted of 13 subjects (mean age, 18.5 ± 2.3 years) who were treated with SARME. In both groups, all cases had a maxillary width deficiency with bilateral crossbites. Maxillary dental casts were available at three different intervals: pretreatment (T1), after orthodontic treatment (T2), and at follow-up recall (T3). Intermolar and interpremolar width, palatal height, and maxillary arch depth and length were assessed from maxillary dental casts. Results: Treatment by RME and SARME produced significant increases in intermolar and interpremolar width and maxillary arch length after expansion (T2) (P < .05). The amount of relapse was not significantly different 2 years after treatment (P > .05). Conclusions: Although age ranges of the patient groups are different, the dentoalveolar responses of RME and SARME were similar after orthodontic treatment. (Angle Orthod. 2009:79; )

Retention period in children with crossbite

2021 ◽  
Vol 21 (2) ◽  
pp. 118-121
Author(s):  
V. M. Vodolatsky ◽  
R. S. Makatov
Keyword(s):  
Orthodontic Treatment ◽  
Orthodontic Appliances ◽  
Retention Period ◽  
Fixed Orthodontic Appliances ◽  
Transversal Plane ◽  
Group 2 ◽  
Design Characteristics ◽  
Group 1

Relevance. Crossbite is a deformation of the dentoskeletal system in the horizontal (transversal) plane, and it results from a discrepancy between the width of the upper and lower dental arches in the anterior or posterior dentition.Crossbite can arise as an isolated condition, and then it is an independent de-formation of the dentoskeletal system. In some cases, a crossbite is combined with a wrong arch-to-arch relationship in the sagittal and vertical planes.The aim was to analyze the duration of the retention period in children with crossbite after the orthodontic treatment.Materials and methods. We orthodontically treated 18 children with crossbite aged 7 to 18 years. All patients were divided into 2 groups. Group 1 included 14 children from 7 to 14 years old with unilateral crossbite (right-sided – 6, left-sided – 8). Group 2 included 4 children from 9 to 18 years old with bilateral crossbite. All 18 children had a buccal crossbite. All patients underwent orthodontic treatment with removable and fixed orthodontic appliances.Results. The retention period after the orthodontic treatment of crossbite lasted 6-9 months.Conclusions. The analysis demonstrated that the retention period after the orthodontic treatment in children with crossbite averaged 6-9 months. The design characteristics of the or-thodontic appliances did not affect the duration of the retention period in children with crossbite.

scholarly journals Development of Polyps and Cancer in Patients with a Negative Colonoscopy: A Follow-Up Study of More Than 20 Years

2014 ◽  
Vol 2014 ◽  
pp. 1-4
Author(s):  
R. J. L. F. Loffeld
Keyword(s):  
Colorectal Cancer ◽  
Outpatient Clinics ◽  
Exclusion Criterion ◽  
Follow Up Study ◽  
Group 4 ◽  
Hospital Systems ◽  
Group 3 ◽  
Group 2 ◽  
Group 1

Background. Adenomas are missed during colonoscopy. Aim. Assess the occurrence of colorectal cancer (CRC) and polyps in patients with a negative index colonoscopy (IC). Patients and Methods. All patients with a IC in 1992–1994, aged 40 and 60 years, were included. Exclusion criterion was presence of abnormalities, a family history, or surveillance. At the end of 2013 all records were studied in order to gather follow-up information. Results. 394 patients were included in four groups: group 1 patients who died, group 2 patients who were not in the hospital systems anymore, group 3 patients still visiting the hospital but not the department of gastroenterology, and group 4 patients undergoing new colonoscopies. In group 1, 2 patients died of CRC and 4 developed a polyp. No data were available from the patients in group 2. Patients in group 3 visited the outpatient clinics but did not undergo new colonoscopy. Patients in group 4 underwent additional colonoscopies. The yield was 35 patients polyps and three CRCs. Five patients (1.3%) developed CRC, and 39 (9%) developed a polyp. Conclusion. Given these results the number of potentially missed adenomas in IC is very low and the consequences of missed adenomas are highly exaggerated.

scholarly journals Prevalence of Chewing Side Preference in the Deciduous, Mixed and Permanent Dentitions

2011 ◽  
Vol 12 (5) ◽  
pp. 339-342 ◽  
Author(s):  
Daphne Câmara Barcellos ◽  
Alessandra Buhler Borges ◽  
Cesar Rogério Pucci ◽  
Carlos Rocha Gomes Torres ◽  
Sergio Eduardo de Paiva Gonçalves ◽  
...  
Keyword(s):  
Direct Method ◽  
Visual Observation ◽  
Permanent Dentition ◽  
Mixed Dentition ◽  
Chi Square ◽  
Side Preference ◽  
Group 3 ◽  
Group 2 ◽  
And Gender ◽  
Group 1

ABSTRACT Aim This study evaluated the prevalence of the chewing side preference (CSP) in the deciduous, mixed and permanent dentitions. Materials and methods Three-hundred subjects were divided in three groups (n = 100): Group 1 – children with deciduous dentition; group 2—children with mixed dentition; group 3 – subjects with permanent dentition. The CSP was determined using a direct method (visual observation) developed by McDonnell et al. (2004). Descriptive statistic was used to observe the prevalence of CSP. The Pearson's Chi-square was used to investigate signicant associations between gender, presence of CSP and preferred side (right/left). Results and conclusion Eighty-seven percent of group 1 had a CSP. Eighty-two percent of group 2 had a CSP. Seventy-six percent of group 3 had a CSP. There was no statistically significant association between presence of CSP and gender in all groups. There was no statistically significant association between preferred side (right/left) and gender in all groups. Clinical significance There is a higher prevalence of subjects in deciduous, mixed and permanent dentition that presented chewing side preference. The early diagnosis of the presence of chewing side preference can prevent the unilateral chewing pattern with prophylactic therapy applied to the first teeth (deciduous). How to cite this article Barcellos DC, de Paiva Gonçalves SE, da Silva MA, Batista GR, Pleffken PR, Pucci CR, Borges AB, Torres CRG. Prevalence of Chewing Side Preference in the Deciduous, Mixed and Permanent Dentitions. J Contemp Dent Pract 2011; 12(5):339-342.

Enlarging solitary cysticercus granulomas

1994 ◽  
Vol 80 (5) ◽  
pp. 840-843 ◽  
Author(s):  
Vedantam Rajshekhar ◽  
Mathew J. Chandy
Keyword(s):  
Excision Biopsy ◽  
Clinical Progression ◽  
Antituberculous Therapy ◽  
Content Type ◽  
Follow Up Study ◽  
Group 2 ◽  
Original Size ◽  
Patients With Epilepsy ◽  
Group 1

✓ Solitary cysticercus granulomas that produce seizures usually measure less than 20 mm in diameter and diminish in size spontaneously. Unlike live cysticercus cysts, they have not been known to increase in size. In a prospective follow-up study of 93 consecutive patients with epilepsy and small solitary lesions (< 20 mm in diameter) enhancing on computerized tomography (CT), 91 were found to have solitary cysticercus granuloma; of these, seven (7.7%) were diagnosed as having an enlarging cysticercus granuloma. Enlarging lesions were defined as those that, on follow-up CT, had increased by more than 50% of their original size but were still less than 20 mm in diameter (Group 1, three patients) or those that had increased to more than 20 mm (Group 2, four patients). Excision biopsy is recommended for Group 2 solitary lesions, regardless of the clinical progression, to eliminate the possibility of other pathologies. However, a trial of albendazole therapy with early CT re-evaluation (within 4 to 6 weeks) may be warranted in those with Group 1 lesions and in selected patients with Group 2 lesions. It is important to recognize the entity of enlarging solitary cysticercus granuloma to avoid mistaking it for a tuberculoma and treating the patient with empiric antituberculous therapy.

Teeth movement 12 years after orthodontic treatment with and without retainer: relapse or usual changes?

2019 ◽  
Author(s):  
Salem Abdulraheem ◽  
Ulrike Schütz-Fransson ◽  
Krister Bjerklin
Keyword(s):  
Orthodontic Treatment ◽  
Natural Growth ◽  
Lower Incisor ◽  
Irregularity Index ◽  
Lower Jaw ◽  
Group 3 ◽  
Group 2 ◽  
Growth Changes ◽  
Group 1

Summary Aims To identify if lower incisor movements after orthodontic treatment are due to the relapse of the orthodontic treatment or due to natural growth. Subjects and methods The subjects consisted of 92 patients who have had orthodontic treatment, divided into three groups, group 1: 38 individuals had no retainer in the lower jaw. Group 2: 24 individuals had a retainer 0.028 inch, a spring hard wire bonded to the mandibular canines only. Group 3: 30 individuals had a 0.0195-inch Twist-Flex wire, bonded to all mandibular incisors and canines. Study models before orthodontic treatment (T0), immediately after orthodontic treatment (T1), 6 years after orthodontic treatment (T2), and 12 years after orthodontic treatment (T3) were used for the measurements. The wires in groups 2 and 3 were removed after mean 2.6 years (SD 1.49). Little Irregularity Index (LII), inter-canine distance, available mandibular anterior space, and number of crowded incisors were registered. A Tooth Displacement Index (TDI) was developed to measure the tooth displacement directions at T0 and T3. Results The LII showed equal values before treatment (T0) and at the follow-up registrations (T2 and T3). But about 25 per cent of the tooth displacements at T2 and T3 did not exist before treatment, at T0. This indicates usual growth changes and not relapse of the orthodontic treatment. Conclusion As about 25 per cent of the displaced incisors can be considered as an effect of natural growth, not a relapse of the orthodontic treatment, it is valuable to use a displacement index in combination with other variables for investigations of stability after orthodontic treatment. Importance of the present study is that it is possible to differ between relapse and usual growth changes.

Creation of physiologic rhythm by closed loop stimulation in heart failure patients with severe chronotropic incompetence: worldwide first results of a pilot study

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
J Proff ◽  
B Merkely ◽  
R Papp ◽  
C Lenz ◽  
P.J Nordbeck ◽  
...  
Keyword(s):  
Heart Rate ◽  
Closed Loop ◽  
Funding Source ◽  
Chronotropic Incompetence ◽  
First Results ◽  
The Mean ◽  
Group 2 ◽  
Group 1

Abstract Background The prevalence of chronotropic incompetence (CI) in heart failure (HF) population is high and negatively impacts prognosis. In HF patients with an implanted cardiac resynchronisation therapy (CRT) device and severe CI, the effect of rate adaptive pacing on patient outcomes is unclear. Closed loop stimulation (CLS) based on cardiac impedance measurement may be an optimal method of heart rate adaptation according to metabolic need in HF patients with severe CI. Purpose This is the first study evaluating the effect of CLS on the established prognostic parameters assessed by the cardio-pulmonary exercise (CPX) testing and on quality of life (QoL) of the patients. Methods A randomised, controlled, double-blind and crossover pilot study has been performed in CRT patients with severe CI defined as the inability to achieve 70% of the age-predicted maximum heart rate (APMHR). After baseline assessment, patients were randomised to either DDD-CLS pacing (group 1) or DDD pacing at 40 bpm (group 2) for a 1-month period, followed by crossover for another month. At baseline and at 1- and 2-month follow-ups, a CPX was performed and QoL was assessed using the EQ-5D-5L questionnaire. The main endpoints were the effect of CLS on ventilatory efficiency (VE) slope (evaluated by an independent CPX expert), the responder rate defined as an improvement (decrease) of the VE slope by at least 5%, percentage of maximal predicted heart rate reserve (HRR) achieved, and QoL. Results Of the 36 patients enrolled in the study, 20 fulfilled the criterion for severe CI and entered the study follow-up (mean age 68.9±7.4 years, 70% men, LVEF=41.8±9.3%, 40%/60% NYHA class II/III). Full baseline and follow-up datasets were obtained in 17 patients. The mean VE slope and HRR at baseline were 34.4±4.4 and 49.6±23.8%, respectively, in group 1 (n=7) and 34.5±12.2 and 54.2±16.1% in group 2 (n=10). After completing the 2-month CPX, the mean difference between DDD-CLS and DDD-40 modes was −2.4±8.3 (group 1) and −1.2±3.5 (group 2) for VE slope, and 17.1±15.5% (group 1) and 8.7±18.8% (group 2) for HRR. Altogether, VE slope improved by −1.8±2.95 (p=0.31) in DDD-CLS versus DDD-40, and HRR improved by 12.9±8.8% (p=0.01). The VE slope decreased by ≥5% in 47% of patients (“responders to CLS”). The mean difference in the QoL between DDD-CLS and DDD-40 was 0.16±0.25 in group 1 and −0.01±0.05 in group 2, resulting in an overall increase by 0.08±0.08 in the DDD-CLS mode (p=0.13). Conclusion First results of the evaluation of the effectiveness of CLS in CRT patients with severe CI revealed that CLS generated an overall positive effect on well-established surrogate parameters for prognosis. About one half of the patients showed CLS response in terms of improved VE slope. In addition, CLS improved quality of life. Further clinical research is needed to identify predictors that can increase the responder rate and to confirm improvement in clinical outcomes. Funding Acknowledgement Type of funding source: Private company. Main funding source(s): Biotronik SE & Co. KG

scholarly journals Effects of posterior tibial slope on the mid-term results of medial unicompartmental knee arthroplasty

Arthroplasty ◽  
2021 ◽  
Vol 3 (1) ◽  
Author(s):  
Zhijie Chen ◽  
Kaizhe Chen ◽  
Yufei Yan ◽  
Jianmin Feng ◽  
Yi Wang ◽  
...  
Keyword(s):  
Knee Flexion ◽  
Tibial Slope ◽  
Posterior Tibial ◽  
Significant Difference ◽  
Medial Unicompartmental Knee Arthroplasty ◽  
Group 3 ◽  
Group 2 ◽  
Postoperative Knee ◽  
Group 1

Abstract Objective To evaluate the effect of medial posterior tibial slope (PTS) on mid-term postoperative range of motion (ROM) and functional improvement of the knee after medial unicompartmental knee arthroplasty (UKA). Methods Medical records of 113 patients who had undergone 124 medial UKAs between April 2009 through April 2014 were reviewed retrospectively. The mean follow-up lasted 7.6 years (range, 6.2–11.2 years). Collected were demographic data, including gender, age, height, weight of the patients. Anteroposterior (AP) and lateral knee radiographs of the operated knees were available in all patients. The knee function was evaluated during office follow-up or hospital stay. Meanwhile, postoperative PTS, ROM, maximal knee flexion and Hospital for Special Surgery (HSS) knee score (pre−/postoperative) of the operated side were measured and assessed. According to the size of the PTS, patients were divided into 3 groups: group 1 (<4°), group 2 (4° ~ 7°) and group 3 (>7°). The association between PTS and the knee function was investigated. Results In our cohort, the average PTS was 2.7° ± 0.6° in group 1, 5.6° ± 0.9° in group 2 and 8.7° ± 1.2° in group 3. Pairwise comparisons showed significant differences among them (p < 0.01). The average maximal flexion range of postoperative knees in each group was 112.4° ± 5.6°, 116.4° ± 7.2°, and 117.5° ± 6.1°, respectively, with significant difference found between group 1 and group 2 (p < 0.05), and between group 1 and group 3 (p < 0.05). However, the gender, age, and body mass index (BMI) did not differ between three groups and there was no significant difference between groups in terms of pre−/postoperative HSS scores or postoperative knee ROM. Conclusion A mid-term follow-up showed that an appropriate PTS (4° ~ 7°) can help improve the postoperative flexion of knee. On the other hand, too small a PTS could lead to limited postoperative knee flexion. Therefore, the PTS less than 4° should be avoided during medial UKA.

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