Longitudinal Study of Carbohydrate Metabolism in Healthy Obese Pregnant Women

Diabetes Care ◽  
1997 ◽  
Vol 20 (9) ◽  
pp. 1470-1475 ◽  
Author(s):  
E. Sivan ◽  
X. Chen ◽  
C. J. Homko ◽  
E. A. Reece ◽  
G. Boden
2018 ◽  
Vol 2018 ◽  
pp. 1-5
Author(s):  
David Larbi Simpong ◽  
Yaw Asante Awuku ◽  
Kenneth Kwame Kye-Amoah ◽  
Martin Tangnaa Morna ◽  
Prince Adoba ◽  
...  

Background. Iodine deficiency causes maternal hypothyroidism which can lead to growth, cognitive, and psychomotor deficit in neonates, infants, and children. This study examined the iodine status of pregnant women in a periurban setting in Ghana. Methods. This longitudinal study recruited 125 pregnant women by purposeful convenience sampling from the antenatal clinic of the Sefwi Wiawso municipal hospital in Ghana. Urinary iodine concentration (UIC) was estimated by the ammonium persulfate method at an estimated gestational age (EGA) of 11, 20, and 32 weeks. Demographic information, iodized salt usage, and other clinical information were collected using a questionnaire. Results. The prevalence of iodine deficiency among the pregnant women was 47.2% at EGA 11 and 60.8% at both EGA of 20 and 32, whereas only 0.8% of participants not using iodized salt had iodine sufficiency at EGA 32. 18.4%, 20%, and 24% of participants using iodized salt had iodine sufficiency at EGA 11, 20, and 32, respectively. Conclusion. A high prevalence of iodine deficiency was observed among our study cohort.


2018 ◽  
Vol 35 (3) ◽  
pp. 242-246 ◽  
Author(s):  
Masanori Suto ◽  
Kazuhisa Maeda ◽  
Miki Sato ◽  
Takashi Kaji ◽  
Minoru Irahara

2017 ◽  
Vol 14 (4) ◽  
pp. 51-56 ◽  
Author(s):  
Elena V. Ostrovskaya ◽  
Tatiana I. Romantsova ◽  
Andrei N. Gerasimov ◽  
Tamara E. Novoselova

Introduction. Obesity is a major factor for cardiometabolic risk. However, there is a category of obese patients without disorders of lipid, carbohydrate metabolism and cardiovascular disease metabolically healthy obese (MHO). Aim. Our goal was to investigate the prevalence and characteristics of this phenotype compared to patients with metabolic syndrome (MS). Materials and methods. To evaluate the prevalence of the MHO phenotype we analyzed 389 medical records of females aged 1860 years with obesity. Three types of MHO criteria were used: 1) HOMA index (2.7); 2) IDF-criteria of metabolic syndrome, 2005; 3) the BioSHaRE-EU 2013 criteria (obese patients without any symptoms of MS). We conducted a comparative analysis of anthropometry, status of lipid and carbohydrate metabolism, the functional state of the liver. Results. The MHO prevalence was: 34.5% according to HOMA index, according to the definitions of MS 2005 38.6%, in BioSHaRE-EU 9.6%. In groups of MHO and MS dyslipidemia was observed in 27.3 and 49.5% (p0.05), hypertension in 25% and 71.6% (p0.05), steatogepatosis in 47.7% vs 51.3% (p0.05) of observations, respectively. Among comorbidities the gynecological pathology was most prevalent - 50.8 and 61.4% (p0.05), disorders of carbohydrate metabolism differed significantly in frequency- 6.82 and 39.1% of patients (p0.05). Patients with MHO had a shorter duration of the existence of obesity than MS (18.7 vs. 24 years) (p=0.0004) and less likely to have attempted to reduce weight 85.8% and 91.6%. Average BMI, waist circumference, hip circumference, fasting glucose, total cholesterol, insulin basal, basal C-peptide, HOMA index in groups of MHO and MS differed significantly (p0.05). Median ALT was 20 and 23.2 U/l, AST 20 and 23 U/l, triglycerides 1.1 and 1.8 mmol/l, high-density lipoprotein 1.4 and 1.1 mmol/l, respectively. Conclusions. The MHO prevalence was maximal according to the MS definitions from 2005, and minimal with BioSHaRE-EU criteria. The main analyzed indicators differed significantly in groups MHO and MS. Longer obesity existence in the MS group may suggest an instability of MHO phenotype over time.


2018 ◽  
Vol 105 ◽  
pp. 71-77 ◽  
Author(s):  
Masako Ohara ◽  
Masahiro Nakatochi ◽  
Takashi Okada ◽  
Branko Aleksic ◽  
Yukako Nakamura ◽  
...  

2019 ◽  
Vol 23 (9) ◽  
pp. 2610-2617 ◽  
Author(s):  
Linda Minja ◽  
Cody Cichowitz ◽  
Brandon A. Knettel ◽  
Michael J. Mahande ◽  
Godfrey Kisigo ◽  
...  

Author(s):  
Iwanowicz-Palus ◽  
Zarajczyk ◽  
Pięta ◽  
Bień

Carbohydrate metabolism disorders resulting in hyperglycemia are among the most common metabolic complications of pregnancy. According to 2017 data from the International Diabetes Federation (IDF), 16.2% of pregnancies are complicated with hyperglycemia, of which gestational diabetes mellitus (GDM) accounts for 86.4% of cases. Carbohydrate metabolism disorders developing during pregnancy require the patient to change her lifestyle or, in some cases, to undergo pharmaceutical treatment, which may affect various aspects of the patient’s life, including her perceived quality of life (QoL). The purpose of the present study was to evaluate levels of QoL, social support, acceptance of illness, and self-efficacy among pregnant patients with hyperglycemia. The study was performed between July 2016 and September 2017 in a group of hyperglycemic pregnant women. The following instruments were used: the World Health Organization Quality of Life—BREF (WHOQOL-BREF), the Berlin Social Support Scales (BSSS), the Acceptance of Illness Scale (AIS), the Generalized Self-Efficacy Scale (GSES) and a standardized interview questionnaire. Participants rated their overall QoL (3.64 points) higher than their overall perceived health (3.43). In terms of social support, the highest scores were obtained in terms of actually received support (3.53) and perceived available instrumental support (3.52), while the lowest in terms of support seeking (2.99) and the need for support (2.95). The mean acceptance of illness score among the hyperglycemic pregnant women that were studied was 31.37, and the mean generalized self-efficacy score was 31.58. Participants’ reported QoL in the various WHOQOL-BREF domains was associated with specific social support scales, acceptance of illness, and generalized self-efficacy.


Nutrients ◽  
2020 ◽  
Vol 12 (4) ◽  
pp. 1152
Author(s):  
Simona Najpaverova ◽  
Miroslav Kovarik ◽  
Marian Kacerovsky ◽  
Zdenek Zadak ◽  
Miloslav Hronek

Maternal nutrition and metabolism play important roles for the well-being of both mother and fetus during pregnancy. This longitudinal study brings an original evaluation of the relationship between the nutritional energy and macronutrients intake (NEMI) and pregnancy outcomes and an assessment of the changes in such intake over the previous ten years. Sixty-five healthy Czech pregnant women were examined in three pregnancy periods (1st: 17th–27th; 2nd: 28th–35th; 3rd: 36th–38th gestational weeks). Results of 7-day dietary records were analyzed using NutriDan software. Energy intake decreased from 30.0 kcal/kg to 25.0 kcal/kg during pregnancy. The data also showed a decrease in macronutrients intake (p < 0.0001) with the advancing stage of pregnancy. Positive correlations were demonstrated between NEMI and birth weight (r = 0.410, p < 0.001). In the second pregnancy period, NEMI (excluding carbohydrates) positively associated with neonatal birth length (p < 0.01) and negatively with duration of birth (p < 0.05). An increased NEMI in the last period of pregnancy shortened the length of pregnancy.


2020 ◽  
Vol 8 (4) ◽  
pp. 1306-1311
Author(s):  
Renuka M ◽  
Nayanabai Shabadi ◽  
Praveen Kulkarni ◽  
D. Sunil Kumar ◽  
G. Anup ◽  
...  

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