scholarly journals Independent Predictors of Delay in Emergence From General Anesthesia

2015 ◽  
Vol 62 (1) ◽  
pp. 8-13 ◽  
Author(s):  
Shigeru Maeda ◽  
Yumiko Tomoyasu ◽  
Hitoshi Higuchi ◽  
Minako Ishii-Maruhama ◽  
Masahiko Egusa ◽  
...  

Abstract Some patients with intellectual disabilities spend longer than others in emergence from ambulatory general anesthesia for dental treatment. Although antiepileptic drugs and anesthetics might be involved, an independent predictor for delay of the emergence remains unclear. Thus, a purpose of this study is to identify independent factors affecting the delay of emergence from general anesthesia. This was a retrospective cohort study in dental patients with intellectual disabilities. Patients in need of sedative premedication were removed from participants. The outcome was time until emergence from general anesthesia. Stepwise multivariate regression analysis was used to extract independent factors affecting the outcome. Antiepileptic drugs and anesthetic parameters were included as predictor variables. The study included 102 cases. Clobazam, clonazepam, and phenobarbital were shown to be independent determinants of emergence time. Parameters relating to anesthetics, patients' backgrounds, and dental treatment were not independent factors. Delay in emergence time in ambulatory general anesthesia is likely to be related to the antiepileptic drugs of benzodiazepine or barbiturates in patients with intellectual disability.

2015 ◽  
Vol 9 (1) ◽  
pp. 146-149 ◽  
Author(s):  
Shigeru Maeda ◽  
Yumiko Tomayasu ◽  
Hitoshi Higuchi ◽  
Minako Ishii-Maruhama ◽  
Ayaka Yamane ◽  
...  

Purpose:The purpose of this study was to identify independent factors associated with prolonged recovery time after intravenous sedation for dental treatment in patients with intellectual disabilities.Methods:This study was designed as a prospective cohort study. Participants were patients with intellectual disabilities, for whom sedation for dental treatment was planned in Okayama University Hospital. The outcome variable was recovery time. The predictor variables were patient background, antiepileptic and psychotropic drugs, and anesthesia-related variables. Factors affecting the outcome were examined with multiple regression analysis.Results:We enrolled 260 cases in this study. Oral midazolam was a strong independent determinant in prolonged recovery time. Teeth extraction, short treatment time and lower body mass index were significant independent predictors of prolonged recovery time.Conclusion:Oral midazolam is a clear independent determinant of prolonged recovery time after sedation, while psychotropic drugs and antiepileptic drugs were not independent determinants in this study.


2019 ◽  
Vol 10 (1) ◽  
pp. 54
Author(s):  
Ha Hong Nguyen ◽  
Trung Thanh Nguyen

Studying the factors affecting the income of Vietnamese peasants: A case in Tra Vinh province, by data collection method of 170 peasants’ households in 4 districts: Cau Ngang, Cang Long, Chau Thanh and Tieu Can in Tra Vinh province, Vietnam. The authors use multivariate regression analysis method. The study has found the factors such as gender of households’s heads, ages of households’ heads, education levels, the number of family members, dependency rates, application of technical advances, production areas affecting the income of peasants in these areas. Since then, the study has implied a policy to improve the income of peasants. For example, it could be very important for us to focus on training science and technology in agriculture, diversify crops and livestock in agriculture, improve techniques and enhance education levels to increase income for peasants in Tra Vinh province in the future.


2013 ◽  
Vol 60 (1) ◽  
pp. 11-14
Author(s):  
Yoshinao Asahi ◽  
Shiro Omichi ◽  
Seita Adachi ◽  
Hajime Kagamiuchi ◽  
Junichiro Kotani

Abstract Many patients with disabilities need recurrent dental treatment under general anesthesia because of high caries prevalence and the nature of dental treatment. We evaluated the use of a nasal device as a possible substitute for flexible laryngeal mask airway to reduce the risk of unexpected failure accompanying intubation; we succeeded in ventilating the lungs with a cut nasotracheal tube (CNT) with its tip placed in the pharynx. We hypothesized that this technique would be useful during dental treatment under general anesthesia and investigated its usefulness as part of a minimally invasive technique. A prospective study was designed using general anesthesia in 37 dental patients with disabilities such as intellectual impairment, autism, and cerebral palsy. CNT ventilation was compared with mask ventilation with the patient in 3 positions: the neck in flexion, horizontal position, and in extension. The effect of mouth gags was also recorded during CNT ventilation. The percentages of cases with effective ventilation were similar for the 2 techniques in the neck extension and horizontal positions (89.2–97.3%). However, CNT ventilation was significantly more effective than mask ventilation in the neck flexion position (94.6 vs 45.9%; P < .0001). Mouth gags slightly reduced the rate of effective ventilation in the neck flexion position. Most dental treatments involving minor oral surgeries were performed using mouth gags during CNT ventilation. CNT ventilation was shown to be superior to mask ventilation and is useful during dental treatment under general anesthesia.


Author(s):  
Le Van Phuc ◽  
Nguyen Hoang Ngoc Linh

<p><strong>Abstract:</strong> The purpose of this study is to examine the factors affecting the motivation of civil servants at the People's Committee of Thua Thien Hue province. Based on data collected from 181 officers at the People's Committee of Thua Thien Hue Province,  researchers processed all data by SPSS with some techniques such as: descriptive statistics, Cronbach's Alpha, Exploratory Factor Analysis (EFA) and Multivariate Regression Analysis... The research results show that there are 6 factors affecting the motivation of officers at the People's Committee of Thua Thien Hue province, including: (i) Working conditions; (ii) Nature of work; (iii) Career development opportunities; (iv) Income and benefits; (v) Relationship with leaders and (vi) Relationships with colleagues. Based on the research results, a number of solutions have been proposed to improve the work motivation in the People's Committee of Thua Thien Hue.</p><p><strong>Keywords: </strong>work motivation, civil servants, Thua Thien Hue Provincial People's Committee</p>


2014 ◽  
Vol 1065-1069 ◽  
pp. 2353-2356
Author(s):  
Bei Lei Xu ◽  
Li Ding Liu ◽  
Bai Feng Ji

China’s southeast coast is one of the regions with most severely influenced by typhoons in the world, which suffers significant casualties and huge economic losses every year. A multiple regression prediction model of the economic losses educed by typhoon disaster in coastal areas of southeastern china was proposed. The principles of multivariate regression analysis were introduced firstly and the Typhoon disaster data over the east coast of China were analyzed. Then, the affected area, deaths and houses collapsed were chose as the variables and a multivariate regression prediction model of the economic losses educed by typhoon disaster was proposed. The results indicate that the factors affecting the economic losses of typhoon disasters randomness were taken into account and the responses of the independent variables and the dependent variable from the statistical data were provided.


2019 ◽  
Author(s):  
Shiroh Nakamoto ◽  
Hiroki Ogata ◽  
Ayano Saeki ◽  
Ryusuke Ueki ◽  
Nobutaka Kariya ◽  
...  

Abstract Background: Early detection of postoperative increase in C-reactive protein (CRP) predicts complications after surgery. The preoperative and intraoperative factors associated with postoperative CRP changes are potentially significant in the prophylactic management of postoperative complications. Although ongoing nociception during surgery under general anesthesia is one of potential candidates for these factors, it has not been evaluated with the unavailability of valid nociception measures in clinical practice. Then we adopted averaged values of nociceptive response (NR) throughout surgery as intraoperative nociceptive levels, being examined the association between perioperative factors, early changes in postoperative CRP levels, and postoperative complications Material and Methods: Data from 174 adult patients undergoing elective non-cardiac surgery under general anesthesia on perioperative variables, including age, sex, BMI, American Society of Anesthesiologists-physical status (ASA-PS), duration of surgery, mean NR during surgery as intraoperative nociceptive level, CRP levels before and after surgery on postoperative day (POD) 1, and postoperative complications using the extended Clavien-Dindo classification were retrospectively obtained in a training cohort. Multivariate regression analysis was performed to determine the independent factor of CRP levels on POD1and to develop a prediction model. In two validation cohorts, both 75 patients undergoing mastectomy (validation cohort A) and 139 patients undergoing laparoscopic or open abdominal surgery (validation cohort B) were separately selected, and retrospectively utilized to evaluate the value of the prediction model. Results: CRP levels on POD1 in the training cohort significantly increased in the order of Clavien-Dindo grades. Multivariate regression analysis selected mean NR, BMI, and duration of surgery to set up the prediction model of CRP level on POD1, which showed significant correlation with the measured CRP in both two validation cohorts. To confirm associations between mean NR, postoperative CRP, and major complications (Clavien-Dindo grade ≥ IIIa), we performed a propensity score matching in the validation cohort B, using age, BMI, ASA-PS, and duration of operations, finding that both mean NR and CRP levels on POD1 were significantly higher in patients with major complications than those without major complications. Conclusion: Increases in the intraoperative nociceptive level likely associated with early increases in CRP level after surgery. Keywords: C-reactive protein, Postoperative complications, Nociception.


2016 ◽  
Vol 2016 ◽  
pp. 1-6 ◽  
Author(s):  
Angela Galeotti ◽  
Annelyse Garret Bernardin ◽  
Vincenzo D’Antò ◽  
Gianmaria Fabrizio Ferrazzano ◽  
Tina Gentile ◽  
...  

Aim. To evaluate the effectiveness and the tolerability of the nitrous oxide sedation for dental treatment on a large pediatric sample constituting precooperative, fearful, and disabled patients.Methods. 472 noncooperating patients (aged 4 to 17) were treated under conscious sedation. The following data were calculated: average age; gender distribution; success/failure; adverse effects; number of treatments; kind of dental procedure undertaken; number of dental procedures for each working session; number of working sessions for each patient; differences between males and females and between healthy and disabled patients in relation to success; success in relation to age; and level of cooperation using Venham score.Results. 688 conscious sedations were carried out. The success was 86.3%. Adverse effects occurred in 2.5%. 1317 dental procedures were performed. In relation to the success, there was a statistically significant difference between healthy and disabled patients. Sex and age were not significant factors for the success. Venham score was higher at the first contact with the dentist than during the treatment.Conclusions. Inhalation conscious sedation represented an effective and safe method to obtain cooperation, even in very young patients, and it could reduce the number of pediatric patients referred to hospitals for general anesthesia.


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