Characterization of comorbid conditions burdening hidradenitis suppurativa: a multicentric observational study

2020 ◽  
Vol 155 (3) ◽  
Author(s):  
Andrea Chiricozzi ◽  
Giulia Giovanardi ◽  
Dante R. Caposiena Caro ◽  
Michela Iannone ◽  
Clara De Simone ◽  
...  
Keyword(s):  
Observational Study ◽  
Hidradenitis Suppurativa ◽  
Comorbid Conditions

scholarly journals Bone Pain in Multiple Myeloma (BPMM)—A Protocol for a Prospective, Longitudinal, Observational Study

Cancers ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 1596
Author(s):  
Marta Diaz-delCastillo ◽  
Rebecca E. Andrews ◽  
Aritri Mandal ◽  
Thomas L. Andersen ◽  
Andrew D. Chantry ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Multiple Myeloma ◽  
Observational Study ◽  
Bone Turnover ◽  
Bone Pain ◽  
Subjective Experience ◽  
Prospective Longitudinal ◽  
Bone Turnover Biomarkers

Multiple myeloma (MM) is a bone marrow neoplasia that causes bone pain in 70% patients. While preclinical models of MM have suggested that both nerve sprouting and nerve injury may be causative for the pain, there is a lack of clinical data. Thus, the primary aims of this clinical study are: (1) to provide a deep characterization of the subjective experience of pain and quality of life in MM patients; (2) to investigate disturbances in the bone innervation of MM patients. Secondary aims include exploring correlations between pain and serum inflammatory and bone turnover biomarkers. In a prospective, observational study (clinicaltrials.gov: NCT04273425), patients with suspected MM requiring a diagnostic iliac crest biopsy at Sheffield Teaching Hospital (UK) are invited to participate. Consenting patients answer seven standardized questionnaires assessing pain, quality of life and catastrophizing. Bone turnover biomarkers and inflammatory cytokines are measured in fasting serum samples, and bone innervation is evaluated in diagnostic biopsies. MM patients are invited to a follow-up upon completion of first line treatment. This will be the first deep characterization of pain in MM patients and its correlation with disturbances in bone innervation. Understanding how bone turnover and inflammation correlate to pain in MM is crucial to identify novel analgesic targets for this condition.

scholarly journals PCV146 CHARACTERIZATION OF PATIENTS PRESCRIBED WITH SACUBITRIL/VALSARTAN IN PORTUGAL: A CROSS-SECTIONAL OBSERVATIONAL STUDY (PRIME STUDY)

2019 ◽  
Vol 22 ◽  
pp. S569
Author(s):  
A. Teixeira Rodrigues ◽  
P.A. Laires ◽  
M. Cary ◽  
J.P. Guerreiro ◽  
M. Romão ◽  
...  
Keyword(s):  
Observational Study ◽  
Cross Sectional

Effect of Chronic Kidney Disease and Comorbid Conditions on Health Care Costs: A 10-Year Observational Study in a General Population

2010 ◽  
Vol 31 (3) ◽  
pp. 222-229 ◽  
Author(s):  
Sebastian E. Baumeister ◽  
Carsten A. Böger ◽  
Bernhard K. Krämer ◽  
Angela Döring ◽  
Dirk Eheberg ◽  
...  
Keyword(s):  
Health Care ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
General Population ◽  
Observational Study ◽  
Health Care Costs ◽  
Comorbid Conditions ◽  
Care Costs

scholarly journals Assessment of Morphometric Indices Related to Vernal Flight in Migratory Buntings

2021 ◽  
Vol 7 (2) ◽  
Author(s):  
Gupta Preeti ◽  
Naseem Asma ◽  
Malik Shalie ◽  
Rani Sangeeta
Keyword(s):  
Observational Study ◽  
Body Mass ◽  
Morphometric Analysis ◽  
Tarsus Length ◽  
Morphological Attributes ◽  
Adverse Conditions ◽  
Migratory Songbirds ◽  
Preparatory Phase ◽  
Wing Patterns

Migratory songbirds fly over long distances to avoid adverse conditions at their breeding and wintering grounds, and this phenomenon is known as ‘migration’. This migratory phenomenon is highly energy demanding. The present study was aimed to analyze the morphometric analysis of body mass, beak, wings, tail, and tarsus length of two migratory finches i.e., red-headed (RHB) and black-headed buntings (BHB) to investigate whether they showed differences in their morphological attributes. This observational study shows an understanding of the characterization of wing patterns and differences in the length of tarsus, tail, beak, and wings of both species. The size of the beak, tail, and wings of BHB is significantly different when compared to RHB. In addition, body mass was significantly high in BHB than that of RHB during their spring migration (preparatory phase). T

Sign in / Sign up

Export Citation Format

Share Document