Adults' Performance on a Measure of Visual Closure

1982 ◽  
Vol 55 (3) ◽  
pp. 943-952 ◽  
Author(s):  
Mark P. Vigen ◽  
Ronald A. Goebel ◽  
Larry J. Embree

The Mooney Closure Faces Test has been employed in several studies of right temporal-lobe function. However, the information provided by these studies is somewhat restricted because there has been no systematic attempt to determine what constitutes “normal” performance on this instrument. The present study attempts to rectify partially this situation by testing samples of three distinct populations (college students, vocational-technical students, and relatives of indigent patients) of neurologically intact subjects who differed in age, IQ, educational level, sex, and handedness. Regression showed all of these variables to be significantly correlated with performance on the Mooney Closure Faces Test. The final linear regression model was correlated 0.718 with the Mooney scores and resulted in predictions which were approximately 30% more accurate than those made using the mean of the entire sample alone.

2020 ◽  
Vol 46 (Supplement_1) ◽  
pp. S257-S257
Author(s):  
Jeff Huarcaya

Abstract Background Schizophrenia is a chronic mental disorder, which produces high costs and has a substantial impact on health care budgets globally. This is mainly due to poor global and cognitive functioning in these patients. The objective of this study was to relate global functioning and cognitive functioning in patients with schizophrenia who attend the outpatient clinic of a general hospital in Peru during the years 2018–2019. Methods Non-experimental quantitative study of descriptive cross-sectional correlational type. The sample was for convenience, and consisted of 53 patients with schizophrenia from the “Hospital Nacional de la PNP”. Functioning Assessment Short Test (FAST) was used to assess global functioning, the Screen for Cognitive Impairment (SCIP), cognitive functioning, and a data collection sheets with the history of the disease. The relationship between FAST and SCIP with the qualitative variables was evaluated by the Mann-Whitney U test or Student’s t test depending on whether they met the normality assumptions. The linear correlation between the FAST, the SCIP and the other quantitative variables was evaluated using Spearman’s Rho. A multiple linear regression model was constructed in which all variables other than the total FAST result are considered using the forward method. Results It was found that 34 (62.2%) were male; 52 (98.1%), single; 39, (73.6%) without a current job. We found worse overall functioning in patients with lower educational level (p = 0.005) and without a current job (p = 0.004). The total FAST was correlated with the time of the disease (ρ = 0.334, p <0.05) and with the number of previous psychotic episodes (ρ = 0.354, p <0.01). We found worse cognitive functioning in patients with lower educational level (p = 0.000) and without a current job (p = 0.017). The SCIP total was correlated to the FAST (ρ = 0.542, p <0.01). The multiple linear regression analysis with the total FAST score as the explained variable evidenced the existence of a relationship between variables that is explained by the equation: Y = 57.032 + (-0.521) X1 + (1.896) X2 Where Y is the total FAST score, X1 the total SCIP and X2 the number of previous psychotic episodes. The coefficient of determination was 0.392 and the mean square error of 161.46. The Durbin-Watson statistic was 1,529. Discussion This is the first exploratory pilot analysis of the factors associated with global functioning, with special emphasis on cognitive functioning and the history of the disease, in Peruvian patients with schizophrenia. Patients with higher educational level and those who have a current job showed a better global and cognitive functioning. It was found an indirect and significant relationship of moderate intensity between cognitive functioning and its subtest with global functioning, that is, a lower level of cognitive functioning is related to greater difficulties in the daily functioning of patients with schizophrenia. Both the bivariate analysis and the linear regression model found a relationship between global and cognitive functioning. In the multiple linear regression model, it was found that the total SCIP was the one that had the most influence on global functioning (Beta = -0.528), that is, lower levels of cognitive functioning are related to high levels of poor global functioning. Taking these results into account, we recommend implementing functional and cognitive evaluation programs in patients with schizophrenia at the “Hospital Nacional de la PNP”. Future longitudinal studies should be performed on samples from larger patients, especially with a first psychotic episode, with the purpose of seeking a cause-effect relationship between global and cognitive functioning in patients with schizophrenia.


2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Jibo Wu

The stochastic restrictedr-kclass estimator and stochastic restrictedr-dclass estimator are proposed for the vector of parameters in a multiple linear regression model with stochastic linear restrictions. The mean squared error matrix of the proposed estimators is derived and compared, and some properties of the proposed estimators are also discussed. Finally, a numerical example is given to show some of the theoretical results.


2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Colin S. Hill ◽  
Sarah Han-Oh ◽  
Zhi Cheng ◽  
Ken Kang-Hsin Wang ◽  
Jeffrey J. Meyer ◽  
...  

Abstract Purpose Variation in target positioning represents a challenge to set-up reproducibility and reliability of dose delivery with stereotactic body radiation therapy (SBRT) for pancreatic adenocarcinoma (PDAC). While on-board imaging for fiducial matching allows for daily shifts to optimize target positioning, the magnitude of the shift as a result of inter- and intra-fraction variation may directly impact target coverage and dose to organs-at-risk. Herein, we characterize the variation patterns for PDAC patients treated at a high-volume institution with SBRT. Methods We reviewed 30 consecutive patients who received SBRT using active breathing coordination (ABC). Patients were aligned to bone and then subsequently shifted to fiducials. Inter-fraction and intra-fraction scans were reviewed to quantify the mean and maximum shift along each axis, and the shift magnitude. A linear regression model was conducted to investigate the relationship between the inter- and intra-fraction shifts. Results The mean inter-fraction shift in the LR, AP, and SI axes was 3.1 ± 1.8 mm, 2.9 ± 1.7 mm, and 3.5 ± 2.2 mm, respectively, and the mean vector shift was 6.4 ± 2.3 mm. The mean intra-fraction shift in the LR, AP, and SI directions were 2.0 ± 0.9 mm, 2.0 ± 1.3 mm, and 2.3 ± 1.4 mm, respectively, and the mean vector shift was 4.3 ± 1.8 mm. A linear regression model showed a significant relationship between the inter- and intra-fraction shift in the AP and SI axis and the shift magnitude. Conclusions Clinically significant inter- and intra-fraction variation occurs during treatment of PDAC with SBRT even with a comprehensive motion management strategy that utilizes ABC. Future studies to investigate how these variations could lead to variation in the dose to the target and OAR should be investigated. Strategies to mitigate the dosimetric impact, including real time imaging and adaptive therapy, in select cases should be considered.


Author(s):  
Chahyun Oh ◽  
Boohwi Hong ◽  
Yumin Jo ◽  
Woosuk Chung ◽  
Hoseop Kim ◽  
...  

Background: The optimal insertion length for right subclavian vein catheterization in infants has not been determined. This study retrospectively compared landmark-based and linear regression model-based estimation of optimal insertion length for right subclavian vein catheterization in pediatric patients of corrected age < 1 year. Methods: Fifty catheterizations of the right subclavian vein were analyzed. The landmark related distances were: from the needle insertion point (I) to the tip of the sternal head of the right clavicle (A) and from A to the midpoint (B) of the perpendicular line drawn from the sternal head of the right clavicle to the line connecting the nipples. The optimal length of insertion was retrospectively determined by reviewing post-procedural chest radiographs. Estimates using a landmark-based equation (IA + AB – intercept) and a linear regression model were compared with the optimal length of insertion. Results: A landmark-based equation was determined as IA + AB – 5. The mean difference between the landmark-based estimate and the optimal insertion length was 1.0 mm (95% limits of agreement –18.2 to 20.3 mm). The mean difference between the linear regression model (26.681 – 4.014 × weight + 0.576 × IA + 0.537 × AB – 0.482 × postmenstrual age) and the optimal insertion length was 0 mm (95% limits of agreement –16.7 to 16.7 mm). The difference between the estimates using these two methods was not significant. Conclusion: A simple landmark-based equation may be useful for estimating optimal insertion length in pediatric patients of corrected age < 1 year undergoing right subclavian vein catheterization.


2020 ◽  
Vol 11 (4) ◽  
pp. 7229-7233
Author(s):  
Anuradha G ◽  
Santhini Gopalakrishnan S ◽  
Vinodakumar H R

The current study was conducted to observe the relationship between serum uric acid, lipid profile and fasting plasma glucose in type 2 DM patients. It was a cross-sectional study. A total of 618 participants were included in the study (203-healthy, 206-prediabetic and 209-T2DM). One way analysis of variance was used to compare the mean between these three groups. A linear regression model was used to find the relationship between SUA and FPG in T2DM. The mean values of serum uric acid in pre-diabetes and T2DM (4.929±1.33 and 4.69±1.41 mg/dl, respectively) were lower compared to healthy (5.40±1.08 mg/dl). SUA showed a significant positive correlation with serum triglycerides in T2DM (p<0.05). The linear regression model showed that SUA was inversely associated with FPG in T2DM after adjustment for age and gender. The biological interrelationship observed in the current study raises the possibility of potential pathogenic overlap between SUA and FPG. SUA might be involved in a metabolic imbalance which in turn leads to T2DM.


2021 ◽  
Vol 26 (2) ◽  
Author(s):  
Bader Aboud ◽  
Mustafa Ismaeel Naif

In the linear regression model, the restricted biased estimation as one of important  methods to addressing the high variance and the  multicollinearity problems. In this paper, we make the simulation study of the some restricted biased estimators. The mean square error (MME) criteria are used to make a comparison  among them. According to the simulation study we observe that, the performance of the restricted modified unbiased  ridge regression estimator (RMUR) was proposed by  Bader and Alheety (2020)  is better than  of these estimators. Numerical example have been considered to illustrate the performance of the estimators.


Author(s):  
M. Evers ◽  
A. Thiele ◽  
H. Hammer ◽  
E. Cadario ◽  
K. Schulz ◽  
...  

Abstract. Persistent Scatterer Interferometry (PSInSAR) exploits a time series of Synthetic Aperture Radar (SAR) images to estimate the mean velocity with which the surface of the earth is deforming. However, most PSInSAR algorithms estimate the mean velocities using a linear regression model. Since some deformation phenomena can exhibit a more complex behavior over time, using a linear regression model leads to potentially wrong estimations for the mean velocity. For example, the velocity of a landslide moving down a steep slope can change depending on the water content of the material of the landslide, or an inactive landslide can reactivate due to an earthquake. Both scenarios would not result in a time series with a constant linear slope but in a piecewise linear time series.This paper presents a Matlab-based tool to analyze an individual Persistent Scatterer (PS) time series. The Persistent Scatterer Deformation Pattern Analysis Tool (PSDefoPAT) aims to build a mathematical model that sufficiently describes the time series trend and seasonal and noise components. The trend component is estimated using polynomial regression and piecewise linear models, while a sine function approximates the seasonal component. The goal is to identify the best fitting model for the displacement time series of a PS. PSDefoPAT is introduced by examine the time series of three different PS located in the region surrounding Patras, Greece. Based on the derived models, we discuss the nature of their deformation patterns.


2021 ◽  
Vol 39 (6_suppl) ◽  
pp. 228-228
Author(s):  
Vidit Sharma ◽  
Abhishek Venkataramana ◽  
W. Scott Comulada ◽  
Mark S. Litwin ◽  
Christopher Saigal

228 Background: While PSA screening was found to reduce prostate cancer metastasis and mortality in a large European randomized trial, PSA screening has also resulted in over-treatment of prostate cancer with significant quality-of-life implications. As a result, the US Preventive Services Task Force (USPSTF) did not recommend PSA screening in 2008 and 2012. It is unknown if reductions in PSA screening were responsible for increased metastatic prostate cancer in the United States. We test this hypothesis by associating longitudinal variations across individual states in PSA screening with their incidence of metastatic prostate cancer at diagnosis from 2002 to 2016. Methods: Age-adjusted incidences of metastatic prostate cancer at diagnosis per 100,000 men were obtained from the North American Association of Central Cancer Registries in 2002 – 2016 for each state. Survey-weighted PSA screening estimates for each state were extracted from the Behavioral Risk Factor Surveillance System, which collects this information for men at least 40 years of age every 2 years from 2002 onward. PSA screening and metastasis data were collated as a multi-panel time series and then analyzed using a random-effects linear regression model with random effects at the state level. Results: There was significant variation between states in the percent of men age >40 years who reported ever receiving PSA screening (range 40.1% to 70.3%) and in the age-adjusted incidence of metastatic prostate cancer at diagnosis (range 3.3 to 14.3 per 100,000). From 2008 to 2016, the mean percentage of men screened decreased (61.8% to 50.5%) whereas the mean incidence of metastatic prostate cancer at diagnosis increased (6.4 to 9.0 per 100,000; Bonferroni adjusted p < 0.001 for both). A random-effects linear regression model demonstrated that longitudinal reductions across states in PSA screening were associated with increased metastatic prostate cancer (regression coefficient per 100,000 men: 14.9, 95% CI 12.3 – 17.5, p < 0.001). This indicated that states with larger declines in PSA screening had larger increases in the incidence of metastatic prostate cancer at diagnosis. Variation in PSA screening explained 27% of the longitudinal variation in metastatic prostate cancer within states. Conclusions: In the context of randomized trial data demonstrating a metastasis reduction with PSA screening, our study strengthens the epidemiologic evidence that reductions in PSA screening may explain some of the recent increase in metastatic prostate cancer at diagnosis in the United States. The trend of rising metastatic disease at diagnosis is a worrisome consequence that needs attention. Thus, we support shared-decision making policies, such as the 2018 USPSTF update, that may optimize PSA screening utilization to reduce the incidence of metastatic prostate cancer in the United States.


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