Extreme Hypothermia Induced by a Synergism of Acute Limbic Seizures, Physical Restraint, and Acepromazine: Implications for Survival following Brain Injury

1993 ◽  
Vol 72 (1) ◽  
pp. 248-250 ◽  
Author(s):  
Y. R. J. Bureau ◽  
M. A. Persinger
Keyword(s):  
Brain Injury ◽  
Core Temperature ◽  
Analysis Of Variance ◽  
Physical Restraint ◽  
The Other ◽  
Limbic Seizures ◽  
Systemic Injection ◽  
Variance Design

Core temperature was measured in rats 24 hr. after they had been assigned to one of 8 groups in a 3-way analysis of variance design that involved (1) induction of limbic seizures by a systemic injection of lithium/pilocarpine, (2) physical restraint, and (3) administration of acepromazine. An extraordinarily powerful interaction was noted among seizures, physical restraint, and acepromazine-produced hypothermia (24° C) compared to the other 7 treatments (> 35° C). The putative poikilothermic response is commensurate with the loss of mammalian behaviors that follow these seizures. Implications for survival during the acute stages of brain injury are suggested.

Psychophysically Based Physical Capability Limits For Right Angle Power Tool Operation

2020 ◽  
Vol 64 (1) ◽  
pp. 910-914
Author(s):  
Jonathan Valencia ◽  
Joel Cort
Keyword(s):  
Analysis Of Variance ◽  
The Other ◽  
Mixed Design ◽  
Joint Orientation ◽  
Physical Capability ◽  
Subject Variables ◽  
Group A ◽  
Repeated Analysis ◽  
Post Hoc

A psychophysical methodology was utilized to examine 40 non-skilled female participants performing right-angle power tool (RAPT) fastening tasks. A combination of two between subject variables were examined for a total of four between-subject groups: joint orientation (horizontal and vertical planes) and joint hardness (hard and soft joints). Participants were evenly distributed into one of four joint orientation- hardness groups. Within each group, a combination of three fastening strategies and three fastening frequencies were performed by each participant. The chosen target torque determined the physical capability limits (PCL). A mixed-design repeated analysis of variance with Tukey’ significance post hoc test were used to determine any significance with the measured variables ( p<0.05). Fastening strategy and frequency influenced the chosen torque magnitude. Participants chose significantly higher target torques with the Turbo Tight strategy in comparison to the other two strategies. Furthermore, participants chose to accept lower target torques and forces as fastening frequency increased.

Comparison of plasma progesterone profiles in cyclic, pregnant, pseudopregnant and hysterectomized pigs between 8 and 27 days after oestrus

1988 ◽  
Vol 119 (1) ◽  
pp. 111-116 ◽  
Author(s):  
G. J. King ◽  
R. Rajamahendran
Keyword(s):  
Least Squares ◽  
Analysis Of Variance ◽  
The Other ◽  
Corpora Lutea ◽  
Plasma Progesterone ◽  
The Third ◽  
Secretory Potential ◽  
The Mean

ABSTRACT Plasma progesterone concentrations were compared in cyclic (n = 12), pregnant (n =12), oestradiol-induced pseudopregnant (n=12) and hysterectomized gilts (n=10) between days 8 and 27 after oestrus. The results were grouped into periods covering days 8–13, 14–20 and 21–27 and analysed by least-squares analysis of variance. Plasma progesterone concentrations were significantly (P<0·001) higher in hysterectomized compared with other groups between days 8 and 13. Progesterone concentrations declined rapidly after day 14 in cyclic females and gradually in the other groups. Throughout the third and fourth weeks the mean progesterone concentrations for hysterectomized animals were consistently higher than for pseudopregnant animals (P<0·05). The pregnant group means were below but not significantly different from the hysterectomized means in both of the last two periods. The greater progesterone concentrations in hysterectomized gilts indicated that secretion is high without any conceptus-produced or -mediated luteotrophin, and corpora lutea in cyclic, pregnant or pseudopregnant gilts may never reach full secretory potential. J. Endocr. (1988) 119, 111–116

scholarly journals A Game System for Cognitive Rehabilitation

2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Azrulhizam Shapi’i ◽  
Nor Azan Mat Zin ◽  
Ahmed Mohammed Elaklouk
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Conceptual Framework ◽  
Cognitive Rehabilitation ◽  
The Other ◽  
Rehabilitation Treatment ◽  
Other Hand ◽  
Rehabilitation Exercises

Brain injury such as traumatic brain injury (TBI) and stroke is the major cause of long-term disabilities in many countries. The increasing rate of brain damaged victims and the heterogeneity of impairments decrease rehabilitation effectiveness and competence resulting in higher cost of rehabilitation treatment. On the other hand, traditional rehabilitation exercises are boring, thus leading patients to neglect the prescribed exercises required for recovery. Therefore, we propose game-based approach to address these problems. This paper presents a rehabilitation gaming system (RGS) for cognitive rehabilitation. The RGS is developed based on a proposed conceptual framework which has also been presented in this paper.

Effect of Dramatization on Speaking Skills ond Academic Achievement In English Among Primary Students

2021 ◽  
pp. 163-182
Author(s):  
Amit Kauts ◽  
Monika
Keyword(s):  
Academic Achievement ◽  
Analysis Of Variance ◽  
Traditional Method ◽  
The Other ◽  
Primary Students ◽  
Control Group ◽  
Gain Scores ◽  
Achievement Gain ◽  
Experimental Group ◽  
Speaking Skills

The present study intends to examine the effect of dramatization on speaking skills and academic achievement in English among primary students. The sample consisted of 240 fifth class students from four co-educational private schools of district Fazilka. The sample was divided into two groups randomly. One of the two groups was designated as Experimental Group and the other as Control Group. Experimental group was taught through Dramatization and the control group was taught through traditional method. The obtained data was analysed using two way Analysis of Variance. The results revealed that (i) Teaching through dramatization was found effective than traditional method with respect to achievement of students in English and gain scores in speaking skills (ii) Boys outperformed girls in case of achievement gain scores (iii) Girls outperformed boys in case of gain scores of speaking skills.

Simulating the action of zeitgebers on a coupled two-oscillator model of the human circadian system

1984 ◽  
Vol 247 (3) ◽  
pp. R418-R426
Author(s):  
P. H. Gander ◽  
R. E. Kronauer ◽  
C. A. Czeisler ◽  
M. C. Moore-Ede
Keyword(s):  
Core Temperature ◽  
Activity Rhythm ◽  
Human Subjects ◽  
Model Performance ◽  
The Other ◽  
Oscillator Model ◽  
Temporal Isolation ◽  
The Core ◽  
Temperature Rhythm ◽  
Rest Activity

Our two-oscillator model was originally designed to describe the circadian rhythms of human subjects maintained in temporal isolation. The performance of this model in response to simulated environmental synchronizing cycles (zeitgebers) is examined here. Six distinct types of synchronization are demonstrated between the x oscillator (postulated to regulate the core temperature rhythm), the y oscillator (postulated to regulate the rest-activity rhythm), and z (the zeitgeber). Four types of synchronization are identifiable, if we consider only the periods of the three oscillators. Both x and y may be synchronized by z; either may synchronize with z while the other exhibits a different period; or x, y, and z may each show different periods. Two further classes of synchronization are discernible when phase criteria are taken into account. When either x or y is on the verge of desynchronizing from the other two oscillators, it undergoes periodic phase modulations while retaining the common overall period. The type of synchronization observed depends on the periods of x, y, and z and on the strength of the z drive. The effects of modifying each of these parameters have been systematically investigated by simulation, and model performance is summarized in terms of range of entrainment "maps." These constitute extensive sets of predictions about expected patterns of entrainment of the core temperature and rest-activity rhythms of human subjects exposed to various environmental zeitgebers. Experimental data are available against which model predictions can be tested.

Synergistic induction of severe hypothermia (poikilothermia) by limbic seizures, acepromazine and physical restraint

2001 ◽  
Vol 70 (2-3) ◽  
pp. 341-352 ◽  
Author(s):  
M.A Persinger ◽  
R.P O'Connor ◽  
Y.R.J Bureau ◽  
G.H Parker ◽  
O Peredery ◽  
...  
Keyword(s):  
Physical Restraint ◽  
Limbic Seizures ◽  
Severe Hypothermia ◽  
Synergistic Induction

Using Mystat to Analyze a Repeated-Measures Design

1991 ◽  
Vol 73 (3) ◽  
pp. 757-758 ◽  
Author(s):  
John F. Walsh
Keyword(s):  
Analysis Of Variance ◽  
Repeated Measures ◽  
Laboratory Experiments ◽  
Repeated Measures Design ◽  
Variance Design

Laboratory experiments having a two-way analysis of variance design with repeated-measures on one factor are analyzed by MYSTAT. The key is in coding subjects as a factor and expressing the design as a three-way factorial with one subject per cell.

Relationship between Speed and Accuracy in an over-Arm Throw

1984 ◽  
Vol 59 (1) ◽  
pp. 219-222 ◽  
Author(s):  
Catherine Indermill ◽  
William S. Husak
Keyword(s):  
Analysis Of Variance ◽  
Repeated Measures ◽  
Maximum Velocity ◽  
The Other ◽  
Spatial Accuracy ◽  
Fitts Law ◽  
Speed And Accuracy ◽  
Muscular Coordination

Principles of force and variability of force suggest that generating maximal forces will result in greater spatial accuracy. 18 right-handed males performed an over-arm throwing task at 50, 75, and 100% of maximum velocity while attempting to hit an archery target. A one-way analysis of variance of velocity with repeated measures on the target showed that the 75% condition was significantly more accurate than either of the other two. The principles may not be generalizable to tasks involving muscular coordination; it seems Fitts' Law may be more applicable.

scholarly journals Long-term evaluation of crown and root discoloration induced by different endodontic sealers

2018 ◽  
Vol 17 ◽  
pp. e18483
Author(s):  
Beatriz Serrato Coelho ◽  
Paula Pontes Garcia ◽  
Flávia Sens Fagundes Tomazinho ◽  
Leonardo Fernandes Cunha ◽  
Denise Piotto Leonardi ◽  
...  
Keyword(s):  
Analysis Of Variance ◽  
Root Canal ◽  
The Other ◽  
Tooth Crown ◽  
Root Canal Filling ◽  
Color Changes ◽  
Term Evaluation ◽  
Ah Plus ◽  
Endodontic Sealers

Aim: To evaluate crown and root discoloration promoted by different endodontic sealers after root canal filling. Methods: Eighty bovine incisors were prepared and filled with: Endofill, Sealer 26, AH Plus, and MTA Fillapex. Color was recorded using a spectrophotometer before endodontic treatment (T0) and at 24 hours (T1), seven days (T2), 30 days (T3), and 90 days (T4) after treatment. Analyses were performed on the middle and cervical regions of the crown, and on the cervical third of the root, immediately below the cementoenamel junction. The color alterations (ΔE) were calculated using Commission International de I’Eclairage (CIE) L*a*b parameters, and data were analyzed by analysis of variance (ANOVA) and Tukey’s test (p<0.05). Results: All sealers induced color alterations. Sealer 26 resulted in the smallest changes in color (E = 5.32). The other materials did not present statistical differences (AH Plus E = 6.98; MTA Fillapex E = 6.88; Endofill E = 6.41). Of the three regions analyzed, the largest discoloration was observed at the cervical third of the root (E=10.67). In terms of time, the largest ΔE values (E=7.72) were observed at T4. Color changes at T1 (E=5.88), T2 (E=6.10), and T3 (E=5.89) were statistically similar. Conclusions: All endodontic sealers promoted discoloration on the tooth crown and root.

The Use of Harmful to Others-Criterion for Involuntary Treatment in Finland

2003 ◽  
Vol 10 (2) ◽  
pp. 183-199 ◽  
Author(s):  
◽  
◽  
◽  
◽  
◽  
...  
Keyword(s):  
Psychiatric Treatment ◽  
Physical Restraint ◽  
Retrospective Chart Review ◽  
The Other ◽  
Involuntary Treatment ◽  
Involuntary Hospitalization ◽  
University Hospitals ◽  
Potential Harm ◽  
Western Countries ◽  
Harm To Others

AbstractDuring the past decades the Western countries have paid attention to their Mental Health legislation, in particular, by making changes concerning involuntary treatment. In Western countries legislation allows involuntary treatmentof the mentally ill. Involuntary psychiatric treatment is motivated by either potential harm to others (for the good of society) or by need for treatment and/or potential self-harm (for the good of the patient). The aims of this study were to describe to what extent the danger to others criterion is used as a motivation for involuntary hospitalization and detainment in Finland, and to what kind of patients this criterion is applied. The study involves a retrospective chart review of all the treatment periods of a six month admission sample in three Finnish university hospitals. We found that potential harm to others has been rarely used as a motivation for involuntary referral or detainment together with other motivations, and virtually never as the sole motivation. With the exception of gender, which was most often male, patients with potential harm to others did not differ significantly from other involuntarily treated patients. Coercion (defined as seclusion, the use of restraints, forced medication, physical restraint or restrictions in leaving the ward) was not used with these patients more regularly than with the patients motivated by the other criteria. Length of stay (LOS) in a psychiatric hospital did not differ between the patients determined harmful to others and the other involuntarily treated patients.

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