The Elderly Patient – Clinical-Pathological Particularities of Left Colon Cancer

AbstractAlmost half of the patients with colorectal cancer are over 70 years old. The aim of the study is to analyse the main clinical and paraclinical characteristics of elderly patients with left colon cancer. 171 patients with left colon cancer were included in a retrospective study, analysing the differences between the patients under and those over 70 years from the point of view of the symptomatology, laboratory investigations, treatment of anemia, postoperative complications. Secondary anemia is seen in a quarter of the patients, and the indication of intraoperative transfusion was most frequent in the elderly (p=0.007). The incidence of intestinal occlusion increases with age, so that one third of the patients over 80 years are admitted with intestinal occlusion. The management of the elderly patient with left colon cancer should benefit from a pluridisciplinary approach, in the context of the numerous associated disorders and the particularities of the geriatric patient.

Download Full-text

Metastatic pattern and tumor sidedness in colorectal cancer.

Journal of Clinical Oncology ◽

10.1200/jco.2019.37.15_suppl.e15147 ◽

2019 ◽

Vol 37 (15_suppl) ◽

pp. e15147-e15147

Author(s):

Mahvish Muzaffar ◽

Abdul Rafeh Naqash ◽

Darla K. Liles ◽

Sumyra Kachru

Keyword(s):

Colorectal Cancer ◽

Colon Cancer ◽

Regression Model ◽

Predictive Factor ◽

Primary Tumor ◽

Left Colon ◽

Cancer Site ◽

Metastatic Colon Cancer ◽

Metastatic Pattern ◽

Left Colon Cancer

e15147 Background: Tumor side has emerged as an important prognostic and predictive factor in metastatic colon cancer. We sought to study its impact on the metastatic pattern of colorectal cancer. Methods: The SEER database (version 8.3.5) was reviewed for patients with Stage IV colorectal cancer diagnosed between 2004-2015. We only included patients with labeled primary site, and excluded appendiceal, unlabeled and autopsy alone cases. Variables included in the analysis were: age, race, gender, grade, primary tumor side and sites of metastasis at diagnosis. Primary outcome analyzed was overall survival and disease specific survival.Cox proportional hazard regression model was employed to test the association between survival and side of cancer/ site of metastasis. Results: A total of 74,768 cases were identified who met the eligibility criteria. The mean age was 68.5 yrs. for right colon cancer (RCC),64.0 yrs. for left colon cancer (LCC). and 62.9 yrs. for rectal cancer. White race was predominant group for RCC, LCC and rectum. More females were vs men in RCC (52% vs 48%), LCC (44% vs 56%) and rectum (60% vs 40%). (The cox regression model suggested inferior outcome for black race HR 1.05(1.03-1.07) (<0.001), high grade HR 1.32(1.30-1.35) p<.0001, right side tumors HR 1.23(1.21-1.250, p <.0001 (table). Conclusions: Over last few years tumor sidedness has emerged as an important prognostic and predictive factor in colon cancer. Our study also highlights the impact of sidedness on survival irrespective of distant metastatic pattern. This analysis contributes to the ongoing discussion that right and left colon cancer are two distinct disease entities. Impact of primary tumor side and metastatic site on survival in colorectal cancer. [Table: see text]

Download Full-text

Colorectal cancer in pregnancy: Two cases report

Vietnam Journal of Endolaparoscopic Surgery ◽

10.51199/vjsel.2018.1.1 ◽

2018 ◽

Vol 8 (1) ◽

Author(s):

Đắc Thao Nguyễn

Keyword(s):

Colorectal Cancer ◽

Rectal Cancer ◽

Colon Cancer ◽

Bowel Obstruction ◽

Left Colon ◽

Third Trimester ◽

The Third ◽

Cancer In Pregnancy ◽

Left Colon Cancer ◽

In Pregnancy

Tóm tắt Nhân hai trường hợp ung thư đại trực tràng ở người bệnh có thai, chúng tôi xin có một số bàn luận quá trình chẩn đoán, điều trị và điểm lại y văn. Trường hợp 1: Ung thư trực tràng 1/3 trên ở người bệnh có thai tuần 27. Giữ thai đến tuần 32. Phẫu thuật lấy thai, cắt đoạn đại tràng xích ma trực tràng kiểu | Hartmann, xét điều trị bổ trợ sau phẫu thuật. Giai đoạn T4NTM0. Trường hợp 2: Người bệnh thai 14 tuần tắc ruột do u đại tràng trái di căn phúc mạc. Phẫu thuật làm hậu môn nhân tạo + sinh thiết u, đình chỉ thai. Người bệnh không điều trị bổ trợ, còn sống sau mổ (10 tháng). Từ khóa: Ung thư đại trực tràng, thai kì, ung thư trong thai kì Abstract We report a case of patient in the third trimester of pregnancy with rectal cancer, and another case of patient at 14 week of pregnancy with left colon cancer presenting bowel obstruction. Keyword: Colorectal cancer, pregnancy, cancer in pregnancy

Download Full-text