scholarly journals Gross and histological evaluation of early lesions of navicular bone and deep digital flexor tendon in horses

2014 ◽  
Vol 58 (1) ◽  
pp. 87-91 ◽  
Author(s):  
Marcin Komosa ◽  
Stanisław Łazowski ◽  
Jan Włodarek ◽  
Karolina Kowalczyk ◽  
Anna Charuta ◽  
...  

Abstract The study aimed at evaluation of pathological lesions on flexor surface of navicular bone and deep digital flexor tendon in horses graded in standard X-ray examination as 2 (fair). The evaluation was performed on fifteen horses (6-9 years of age). Analysis procedure involved examining navicular bones on X-ray pictures, post-slaughter preparation of navicular bones from the hoof capsule, macroscopic evaluation of fibrocartilage on flexor surface, and analysis of histologic preparations. In horses with navicular bones graded as 2, early pathological changes have already developed, even if such horses were not lame. The pathological changes included fibrillation and disruption of deep digital flexor tendon surface, loss of fibrocartillage in sagittal ridge area of navicular bone, thinning of subchondral bone on its flexor surface, and fibromyxoid changes in chondroid matrix. In terms of clinical relevance, more studies are needed to understand the sequence of changes in a better way.

1943 ◽  
Vol 78 (4) ◽  
pp. 285-304 ◽  
Author(s):  
William F. Friedewald ◽  
Rubert S. Anderson

The virus-induced papillomas of cottontail as well as domestic rabbits regress completely within a few weeks when exposed to 5,000 r of x-ray irradiation. The x-rays do not immediately kill the papilloma cells, but lead to death by inhibiting cellular division and producing pathological changes in the cells which then continue to differentiate. The virus associated with the growths, however, not only persists in undiminished amount during regression, but often an increased yield of it can be obtained on extraction. The fibroma virus in crude extracts or in vivo is inactivated by far less irradiation than the papilloma virus. 10,000 r destroys 90 per cent or more of the infectivity of the fibroma virus, whereas at least 100,000 r is required to inactivate 50 per cent of the papilloma virus in extracts containing about the same amount of protein. No variant of the papilloma virus or fibroma virus has been encountered as a result of the irradiation.


2014 ◽  
Vol 27 (05) ◽  
pp. 358-365 ◽  
Author(s):  
P. R. Van Weeren ◽  
C. H. A. Van de Lest ◽  
J. Boere ◽  
M. Reyes ◽  
J. C. Ionita ◽  
...  

SummaryObjective: Even though equine multi-limb tendinopathy models have been reported, it is unknown if fore- and hindlimb tendon healing behave similarly. The aim of this study was to compare the healing process of surgically induced superficial digital flexor tendon (SDFT) core lesions of fore- and hindlimbs in horses.Methods: Tendon core lesions were surgically induced in the SDFT of both fore- and hindlimbs in eight horses. One randomly assigned forelimb and one randomly assigned hindlimb were injected with saline one and two weeks post-surgery. The healing process was monitored clinically and ultrasonographically. After 24 weeks, the tendons were harvested and biochemical, biomechanical and histological parameters were evaluated.Results: Twenty-four weeks post-surgery, the forelimb SDFT lesions had a significantly higher colour Doppler ultrasound vascularization score (p = 0.02) and glycosaminoglycan concentration (p = 0.04) and a significantly lower hydroxylysylpyridinoline content (p = 0.03).Clinical relevance: Our results indicate that fore- and hindlimb SDFT surgically induced lesions exhibit significant differences in several important parameters of tendon healing 24 weeks post-surgery. These differences create significant challenges in using all four limbs and accurately interpreting the results that one might generate. Therefore these findings do not support the use of four-limb models for study of tendon injury until the reasons for these differences are much better understood.


1987 ◽  
Vol 12 (2) ◽  
pp. 229-232
Author(s):  
N. C. NEAL ◽  
J. McMANNERS ◽  
G. A. STIRLING

The histological features of the flexor tendon sheath in the spontaneous carpal tunnel syndrome were studied. The main differences between our findings and previous studies were twofold. Firstly a striking absence of inflammation in our material and secondly the diversity of the pathological changes encountered — alterations in the connective tissue especially the collagen; proliferation with thickening of the tissues of the tendon sheath; fibrosis; amyloid deposition; oedema; vascular lesions including thickening of vessels walls, intimal hyperplasia, and thrombosis; and a foreign body giant cell reaction. Although the lesions described here may not be significant in every case in which they are encountered, they do appear to support the view that pressure in the carpal tunnel and ischaemia are the important factors in a majority of cases of the spontaneous carpal tunnel syndrome.


2008 ◽  
Vol 47 (13) ◽  
pp. 1199-1205 ◽  
Author(s):  
Mitsuhiro Sumitani ◽  
Nobuhide Takifuji ◽  
Shigeki Nanjyo ◽  
Yumiko Imahashi ◽  
Hidemi Kiyota ◽  
...  

1991 ◽  
Vol 35 (B) ◽  
pp. 737-742
Author(s):  
V. I. Smolniakov

AbstractSome x-ray fluorescence - concentration relationships in the framework of XRF were researched. Fundamental calculation approaches for primary fluorescence and incoherent scattering were realized for evaluation of matrix influence. A new binary approach was produced for the cases considered, and its unification was related to the empirical and regression types of the “standard background” technique, widely used in the analytical practice of XRF. It is confirmed that application of the calculations by fundamental parameters (FP) in combination with the empirical approach allows the reduction of the set of standards (to as few as one) in the analysis procedure with wide variations in matrices and concentrations, without loss of accuracy.


2019 ◽  
Vol 64 (1) ◽  
pp. 74-79
Author(s):  
А. Левитов ◽  
A. Levitov ◽  
В. Дога ◽  
V. Doga ◽  
Г. Белицкая ◽  
...  

Slot-radiography is an x-ray examination in which a two-dimensional radiography with a straight beam and further computer stitching of the images obtained on the workstation during a single-pass of x-ray tube over a patient. The application of innovative techniques for image acquisition and processing in combination with a large-area flat panel detector (FPD) makes it possible to produce long-view images from one to several anatomical regions. During the investigation, the x-ray tube and the FPD move simultaneously at a constant speed in parallel relative to one another with the longitudinal axis of the body. Thus, it makes possible to obtain images with little distortion and processed images without visual defects. And this allows conducting more accurate diagnosis of pathological changes. Slot-radiography can be performed both in the patient’s standing position and lying down depending on the region of interest and tasks. It is possible to obtain images in both a frontal and a lateral projection without loss of quality. Slot-radiography is effectively used to diagnose pathological changes in joints and spine, including scoliosis, limb shortening, segmental spinal instability, pathology of lower limb veins, and also as a method for assessing the quality of the treatment. This technique is characterized by safety and convenience for the patient: minimal time costs and low radiation exposure. The application of this technique significantly increases the informative value of the x-ray examination, brings it to a qualitatively new level, providing a physician with a wide range of diagnostic possibilities.


2017 ◽  
Vol 214 (1) ◽  
pp. 19-23 ◽  
Author(s):  
Shelby Resnick ◽  
Kenji Inaba ◽  
Efstathios Karamanos ◽  
Dimitra Skiada ◽  
James A. Dollahite ◽  
...  

2001 ◽  
Vol 16 (1) ◽  
pp. 25-29
Author(s):  
Maria Cristina Comunian Ferraz ◽  
Heitor Cury Basso ◽  
Yvonne P. Mascarenhas

Using a recent proposed analysis procedure for quantitative phase determination by X-ray powder diffraction, YBa2Cu3O7−x solid state formation reaction kinetics at 900 °C was studied. Although there was the presence of partial amorphous components, it was possible to determine a reaction route for the synthesis of the title compound from X-ray powder diffraction data collected at various stages of the thermal treatment and using the Rietveld method for the quantitative determination of the phase composition


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