scholarly journals Overview of The Head CT-Scan in Stroke Patients who was Treated at Muhammadiyah Hospital Palembang

2021 ◽  
Vol 2 (1) ◽  
pp. 24
Author(s):  
Pratrisna Yusastra ◽  
Indriyani Indriyani ◽  
Budi Utama
Keyword(s):  
Ischemic Stroke ◽  
Ct Scan ◽  
Hemorrhagic Stroke ◽  
Right Hemisphere ◽  
Clinical Symptoms ◽  
Neurological Deficits ◽  
Thalamic Lesion ◽  
Stroke Patients ◽  
Head Ct ◽  
The Right

Background: Stroke is a collection of symptoms of neurological deficits due to sudden acute disturbance of brain function, both focal and global, caused by blockage or rupture of arteries and veins and proven by imaging and/or reflex pathology. Using CT-Scan, the description of acute phase stroke can be easier and can determine the appropriate treatment criteria for stroke. Purposes: To determine characteristic Head CT-Scan image of stroke patients hospitalized in Muhammadiyah Palembang Hospital. Methods: This study was conducted in a retrospective descriptive manner and obtained a sample of 41 stroke patients according to the inclusion and exclusion criteria using total sampling. Result: In this study, there were 28 patients (68.2%) with ischemic stroke and 13 patients (31.7%) with hemorrhagic stroke. Head CT-Scan image of ischemic stroke shows basal ganglia lesion (28.5%) and the right hemisphere lesions (57.1%) as the most predominant area. Head CT-Scan image of hemorrhagic stroke (58.3%) had intracerebral hemorrhage with the dominant thalamic lesion area (66.6%) and the right hemisphere (58.3%) had the most lesions with 8 patients (66, 6%) had a midline shift. Stroke patients were treated as experienced by the elderly (90.2%) and were dominated by the female sex (63.4%) and are dominated by clinical symptoms of hemiparesis (29.2%). Conclusion: Stroke patients at Muhammadiyah Palembang hospital dominated by ischemic stroke and on head CT Scan image predominantly shows lesions on the right cerebral hemisphere.

scholarly journals Hasil pemeriksaan CT scan pada penderita stroke non hemoragik di Bagian Radiologi FK Unsrat/SMF Radiologi RSUP Prof. Dr. R. D. Kandou Manado periode Agustus 2015 – Agustus 2016

e-CliniC ◽  
2016 ◽  
Vol 4 (2) ◽  
Author(s):  
Christian Elim ◽  
Vonny Tubagus ◽  
Ramli Hadji Ali
Keyword(s):  
Ct Scan ◽  
Hemorrhagic Stroke ◽  
Right Hemisphere ◽  
Secondary Data ◽  
Haemorrhagic Stroke ◽  
Descriptive Study ◽  
Body Parts ◽  
Stroke Patients ◽  
The Right ◽  
The Brain

Abstract: CT-scan is used to analyze the structures of specific body parts, mainly to confirm the diagnosis of non-hemorrhagic stroke. Stroke is a neurological deficit that occurs suddenly and caused by the interruption of blood flow to the brain. The symptoms are corresponding to the location of the stroke. This study was aimed to obtain the CT-scan examination of non-haemorrhagic stroke patients. This was a retrospective descriptive study using secondary data such as request letter and data of head CT-scan performed from August 2015 to August 2016. The results showed that there were 89 cases of non-hemorrhagic stroke. The majority were males (60 patients; 67%), elderly ≥65 years old (27 patients; 30%), and location of lesion in the right hemisphere (38 patients; 43%). Conclusion: In this study most patients diagnosed as non-hemorrhagic stroke with CT-scan were males, over 65 years old, and location of lesion in right hemisphere.Keywords: non-haemorrhagic stroke, CT-scan Abstrak: CT scan digunakan untuk menganalisis struktur dalam dari beberapa bagian tubuh tertentu, antara lain untuk memastikan diagnosis dari stroke non hemoragik, Stroke merupakan suatu defisit neurologik yang terjadi secara tiba-tiba diakibatkan oleh adanya gangguan aliran darah ke otak dan gejala yang terjadi sesuai dengan lokasi dari stroke tersebut. Penelitian ini bertujuan untuk mengetahui hasil pemeriksaan CT scan pada penderita stroke non hemoragik. Jenis penelitian ialah deskriptif retrospektif dengan memanfaatkan data sekunder berupa lembar permintaan dan data hasil CT scan kepala yang dilaksanakan sejak Agustus 2015 sampai Agustus 2016. Hasil penelitian mendapatkan sebanyak 89 kasus didiagnosis stroke non-hemoragik dengan CT-scan, terbanyak ialah jenis kelamin laki-laki berjumlah 60 orang (67%); golongan usia manula (≥65 tahun) berjumlah 27 orang (30%); dan lokasi lesi di hemisfer dekstra berjumlah 38 orang (43%). Simpulan: Pada studi ini, majoritas pasien yang didiagnosis stroke non-hemoragik dengan CT-scan Berjenis kelamin laki-laki, usia ≥65 tahun, dengan lokais lesi pada hemisfer kanan. Kata kunci: stroke non hemoragik, CT-scan

Abstract WMP16: Eloquence-Weighted Imaging Improves Clinical Outcomes Prediction in Endovascular Stroke Therapy

Stroke ◽  
2016 ◽  
Vol 47 (suppl_1) ◽  
Author(s):  
Sunil A Sheth ◽  
David S Liebeskind ◽  
Conrad W Liang ◽  
Albert J Yoo ◽  
Reza Jahan ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Ct Scan ◽  
Acute Ischemic Stroke ◽  
Left Hemisphere ◽  
Right Hemisphere ◽  
Infarct Volume ◽  
Good Outcome ◽  
Relative Contribution ◽  
C Statistic ◽  
The Right

Background: Larger infarct size at presentation as determined by ASPECTS is associated with reduced likelihood of good outcome in acute ischemic stroke. However, infarct volume alone explains only a modest fraction (∼30%) of the variation in stroke outcome. Incorporating the relative eloquence of each ASPECTS region may improve the predictive power. Methods: In the combined database of the SWIFT and STAR trials, we identified patients treated with the Solitaire stent retriever. Using the 24hr CT scan, a multivariate linear regression was used to determine the relative contribution of each ASPECTS region, separately in each hemisphere, to freedom from disability (mRS 0-2) at 90 days. The coefficients from the regression were used to create an Eloquence-weighted ASPECTS score (EL-ASPECTS), which was compared against the original in predicting outcome based on the presentation CT scan. Results: Among 254 patients treated with ET, average age was 68, 64% were female, and NIHSS was mean 16 (SD +/- 5). Mean ASPECTS at presentation was 8.2 and 6.4 at 24 hrs. The most commonly involved ASPECTS regions were the lentiform nuclei (70%), insula (55%), and caudate (52%). In multivariate analysis, for the right hemisphere on 24hr CT, preservation of M1 (OR 1.6) and M4 (OR 1.2) regions were most strongly predictive of good outcome. For the left hemisphere on 24 hr CT, preservation of M3 (OR 2.6), and M5 (OR 2.5) and involvement of M2 (OR -1.9) were most predictive. Eloquence weights were assigned to all 20 R/L ASPECTS regions to create EL-ASPECTS. EL-ASPECTS, compared with original ASPECTS, demonstrated improved discrimination for independent functional outcome for right hemisphere (C-statistic 0.78 vs. 0.69), left hemisphere (0.78 vs. 0.72), and all stroke patients (0.76 vs. 0.70). On presentation CTs, multivariate analyses including age and presentation NIHSS demonstrated EL-ASPECTS but not original ASPECTS was predictive of good clinical outcome (OR 1.65, p<.01). Higher C-statistic values were seen with EL-ASPECTS in analysis of presentation CT scans. Conclusions: Incorporation of regional weighting into ASPECTS improves the ability to predict who will achieve independent functional outcomes with endovascular therapy in acute ischemic stroke.

scholarly journals Accuracy of Siriraj stroke scale in the diagnosis of stroke subtypes among stroke patients

2017 ◽  
Vol 5 (3) ◽  
pp. 1084
Author(s):  
Abhilash Somasundaran ◽  
Hashik Mohammed ◽  
Jayaraj Kezhukatt ◽  
Alvin Treasa George ◽  
S. Narayanan Potty
Keyword(s):  
Ischemic Stroke ◽  
Ct Scan ◽  
Rural Areas ◽  
Hemorrhagic Stroke ◽  
Cross Sectional Study ◽  
Stroke Patients ◽  
Stroke Subtype ◽  
Cross Sectional ◽  
Tertiary Centre ◽  
Low Sensitivity

Background: Early detection of intracranial blood is essential for the rational use of anti hemostatic drugs in stroke patients. CT scan is quite expensive as well as it is not easily available especially in the rural areas. Clinical stroke scores were developed to overcome these limitations. Aim of present study is to identify the stroke subtype using Siriraj stroke scoring and thus asses its accuracy by comparing with CT scan reports.Methods: A cross sectional study was conducted in a tertiary centre that evaluated 464 patients admitted with a diagnosis of stroke. Siriraj Stroke score was calculated for each patient and a CT scan of brain was also taken. The results of diagnosis made by Siriraj stroke scoring were compiled and compared with the diagnosis obtained by CT Scan.Results: Of the total 464 patients, the incidence of hemorrhagic stroke was 27.8% and ischemic stroke was 72.2%, as per the CT scan reports, while the Siriraj stroke score diagnosed 16.8% patients to have hemorrhagic stroke and 74.6% to have ischemic stroke and no definite diagnosis was made in rest of the patients (8.6%). The sensitivity of the scoring was found to be 59.2% in diagnosing hemorrhagic stroke and 95.5% in ischemic stroke.Conclusions: Our study has shown that siriraj stroke scoring has a high degree of accuracy in detecting both types of strokes, with roughly 80% of both hemorrhagic and ischemic strokes being correctly identified. However there is a low sensitivity in diagnosing hemorrhagic strokes and higher sensitivity in diagnosing ischemic strokes.

Convexity Subarachnoid Hemorrhage Accompanied by Hyperacute Ischemic Stroke

2020 ◽  
Vol 49 (1) ◽  
pp. 70-78 ◽  
Author(s):  
Takeo Sato ◽  
Kenichiro Sakai ◽  
Masahiro Mimori ◽  
Teppei Komatsu ◽  
Kenichi Sakuta ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Subarachnoid Hemorrhage ◽  
Clinical Characteristics ◽  
Right Hemisphere ◽  
Stroke Onset ◽  
Arterial Stenosis ◽  
Arterial Ischemic Stroke ◽  
Stroke Patients ◽  
Ischemic Lesion ◽  
The Right

Introduction and Objectives: The clinical characteristics of convexity subarachnoid hemorrhage (cSAH) accompanying hyperacute ischemic stroke are unknown. We aimed to investigate the incidence and clinical characteristics of cSAH with hyperacute ischemic stroke. Methods: Participants comprised symptomatic ischemic stroke patients with ≤4.5 h from onset to door who also underwent initial MRI ≤4.5 h from onset. We reviewed initial and follow-up MRI during admission to identify cSAH. Retrospective reviews of cSAH incidence and clinical characteristics were performed. Results: We screened 1,249 consecutive symptomatic ischemic stroke patients, including 384 patients (279 males [73%]; median age, 67 years). Of the 384 patients, arterial ischemic stroke was seen in 382 patients, and venous ischemic stroke in 2 patients. Of the hyperacute arterial ischemic stroke, cSAH was identified within 4.5 h of ischemic stroke onset in 2 patients (0.5%) and around 6 days from ischemic stroke onset in 2 patients (0.5%). Of the hyperacute venous ischemic stroke, cSAH was observed in 1 patient on initial MRI. Comparing the clinical characteristics of hyperacute arterial ischemic stroke with and without cSAH, patients with cSAH were more likely to have arterial stenosis or occlusion ipsilateral to the cSAH (100 vs. 47%, p = 0.048), and the ischemic lesion only in the right hemisphere (100 vs. 33%, p = 0.013). In all cases, outcomes were favorable (modified Rankin Scale 0–1 at 3 months from onset). Conclusions: Convexity SAH was observed in 0.5% of hyperacute ischemic patients within 4.5 h of ischemic stroke onset and in 0.5% around 6 days from ischemic stroke onset.

scholarly journals GAMBARAN HASIL PEMERIKSAAN CT SCAN KEPALA PADA PENDERITA STROKE HEMORAGIK DI BAGIAN RADIOLOGI FK. UNSRAT/SMF RADIOLOGI BLU RSUP PROF. DR. R. D. KANDOU MANADO

e-CliniC ◽  
2015 ◽  
Vol 3 (1) ◽  
Author(s):  
Novita T. A. Parinding ◽  
Ramli Haji Ali ◽  
Vonny N. Tubagus
Keyword(s):  
Ct Scan ◽  
Hemorrhagic Stroke ◽  
Recurrent Stroke ◽  
Secondary Data ◽  
Chronic Hypertension ◽  
Inclusion Criteria ◽  
Cerebral Blood Vessels ◽  
Stroke Patients ◽  
Head Ct ◽  
The Brain

Abstract: Hemorrhagic stroke is a spontaneous blood vessel bursts inside the brain. The main cause is chronic hypertension and the presence of degeneration of cerebral blood vessels. Bleeding can occur in the brain and the subarachnoid space due to rupture of an artery or rupture of the aneurysm. At a stroke, a CT scan is the gold standard examination to distinguish infarction with bleeding, because CT scan can give a very clear picture of the head of the intracranial space persisted as cerebral infarction, intracranial hemorrhage, and hemorrhagic stroke. So it can be helpful to diagnose the disease and neurological disorders. The purpose of this study is to cognize the distribution of hemorrhagic stroke patients who performed a head CT scan at The Department of Radiology of FK UNSRAT / SMF Radiology of BLU Prof. Dr. R. D. Kandou Manado. This is a retrospective descriptive study by using secondary data coming from hemorragic stroke patients medical records in the Department of Radiology of BLU Prof. Dr. R. D. Kandou Manado on the period time from May to October 2014. Patients admitted inclusion criteria age between 30-80 years old, proven hemorrhagic stroke based on history, physical examination and investigations of doctors. The results showed that the total number of head CT Scans are 296 patients and more showed abnormal picture (58.1%) compared with the normal picture (41.9%), there are 64 patients with abnormal CT Scan picture results of hemorrhagic stroke (37.2% ), patients with hemorrhagic stroke are more common in males (65.6%), most in the age group of the early elderly betweeb 46-55 years old (40.6%) with most bleeding type of intracerebral hemorrhage (87.5%). Conclusion: Patient that comes with hemorrhagic stroke case or recurrent stroke should undertake a CT Scan of head to assist diagnose and later on can identify the type of bleeding caused by the stroke.Keywords: head CT scan, haemorrhagic strokeAbstrak: Stroke hemoragik adalah perdarahan spontan di dalam otak. Penyebab utamanya adalah hipertensi kronik dan adanya degenerasi pembuluh darah cerebral. Perdarahan dapat terjadi di dalam otak dan ruang subaraknoid karena ruptur dari arteri atau ruptur dari aneurisma. Pada penyakit stroke, CT Scan merupakan pemeriksaan baku emas untuk membedakan infark dengan perdarahan, karena CT Scan dapat memberikan gambaran kepala yang sangat jelas tentang proses desak ruang intrakranial seperti infark otak, perdarahan intrakranial, dan stroke hemoragik. Sehingga dapat membantu penegakan diagnosis penyakit dan kelainan neurologik. Tujuan penelitian ini untuk mengetahui distribusi penderita stroke hemoragik yang dilakukan pemeriksaan CT Scan kepala di Bagian Radiologi FK UNSRAT/SMF Radiologi BLU RSUP Prof. Dr. R. D. Kandou Manado. Penelitian ini merupakan penelitian deskriptif retrospektif dengan memanfaatkan data sekunder berupa rekam medik pasien stroke hemoragik di Bagian Radiologi BLU RSUP Prof. Dr. R. D. Kandou Manado periode Mei-Oktober 2014. Pasien yang masuk kriteria inklusi yaitu usia 30-80 tahun, terbukti stroke hemoragik berdasarkan anamnesis, pemeriksaan fisik dan penunjang oleh dokter. Hasil pemeriksaan CT Scan kepala berjumlah 296 pasien dan lebih banyak menunjukkan gambaran abnormal (58,1%) dibandingkan gambaran normal (41,9%), pada gambaran abnormal terdapat 64 penderita dengan hasil CT Scan gambaran stroke hemoragik (37,2%), penderita stroke hemoragik lebih banyak terjadi pada laki-laki (65,6%), paling banyak pada kelompok umur lansia awal 46-55 tahun (40,6%) dengan tipe perdarahan paling banyak yaitu perdarahan intraserebral (87,5%). Simpulan : Penderita yang datang dengan keluhan stroke hemoragik atau stroke berulang sebaiknya melakukan pemeriksaan CT Scan kepala untuk membantu diagnosis dan dapat diketahui tipe perdarahan dari stroke tersebut.Kata kunci : CT scan kepala, stroke hemoragik

scholarly journals GAMBARAN HASIL CT SCAN KEPALA PADA PENDERITA DENGAN KLINIS STROKE NON-HEMORAGIK DI BAGIAN RADIOLOGI FK. UNSRAT / SMF RADIOLOGI BLU RSUP PROF. DR. R. D KANDOU MANADO PERIODE JANUARI 2011- DESEMBER 2011

e-CliniC ◽  
2014 ◽  
Vol 2 (3) ◽  
Author(s):  
Mohammad Arswendo Tjikoe ◽  
Elvie Loho ◽  
Ramli H. Ali
Keyword(s):  
Blood Flow ◽  
Ischemic Stroke ◽  
Ct Scan ◽  
Hemorrhagic Stroke ◽  
Age Group ◽  
Stroke Patients ◽  
Request Form ◽  
Neurologic Diseases ◽  
Short Time ◽  
The Brain

Abstract: Stroke is the most common of neurologic manifestations and easily recognizable from the other neurologic diseases due to the early onset of sudden in a short time. Stroke as clinical diagnosis was divided to hemorrhagic stroke and ischemic stroke. In hemorrhagic stroke there is a rupture in blood vessel so the blood flow became abnormal and bleeds into surrounding brain and damage it. In ischemic stroke the blood flow heading to the brain is interrupted due to atherosclerosis process. The purpose of this study is to know about description of head CT scan in patient with clinical diagnonis of stroke non hemorrhagic in Department/SMF Radiology Faculty Of Medicine UNSRAT BLU RSUP Prof. Dr. R. D. Kandou Manado period on 1st January 2011 – 31st December 2011. Methods: The study design was a retrospective descriptive study. The data are from request form sheet and radiographic response in the Department of Radiology and processed in descriptive. Results: Base on 163 data of stroke patients obtained, 74 patients diagnosed with infarction stroke (45,4%). Male had more (59,5%) than female (40,5%). For age group, 60-79 is the largest with 33 patients (44,6%). Area with most lesion was in parietal dextra lobe with 8 cases (10,8%). Most cases was happened in August with 10 cases (13,5%). Conclusion: Patients with radiology diagnosis infarction stroke, the most common infarction location is in parietal dextra area. Keywords: CT Scan, Infarction Stroke, Parietal Dextra.   Abstrak: Stroke merupakan salah satu manifestasi neurologik yang umum, dan mudah dikenal dari penyakit-penyakit neurologik lain karena mula timbulnya mendadak dalam waktu yang singkat. Stroke sebagai diagnosis klinis terbagi menjadi stroke hemoragik (pendarahan) dan stroke non-hemoragik (iskemik). Pada stroke hemoragik pembuluh darah pecah sehingga aliran darah menjadi tidak normal dan darah yang keluar merembes masuk ke dalam suatu daerah di otak dan merusaknya. Sedangkan pada stroke non-hemoragik aliran darah ke otak terhenti karena aterosklerosis atau bekuan darah yang telah menyumbat suatu pembuluh darah, melalui proses aterosklerosis. Tujuan penelitian ini adalah untuk mengetahui gambaran hasil CT scan kepala pada penderita dengan klinis stroke non-hemoragik di Bagian Radiologi FK. Unsrat / SMF Radiologi BLU RSUP Prof. dr. R. D Kandou Manado periode Januari 2011- Desember 2011. Metode: Penelitian ini merupakan penelitian deskriptif retrospektif dengan memanfaatkan data sekunder berupa lembaran permintaan & jawaban CT scan kepala yang terdapat di bagian Radiologi BLU RSUP Prof. Dr. R. D. Kandou Manado periode 1 Januari 2011 – 31 Desember 2011. Hasil penelitian: Berdasarkan 163 data pasien yang didapatkan, 74 pasien didiagnosis dengan stroke infark (45,4%). Laki-laki lebih banyak (59,5%) dari perempuan (40,5%). Kelompok umur 60-79 merupakan kelompok umur terbanyak yaitu 33 pasien (44,6%). Daerah lesi terbanyak adalah pada daerah parietalis dextra dengan 8 kasus (10,8%). Kasus terbanyak terjadi pada bulan agustus dengan 10 kasus (13,5%). Simpulan: Pada pasien dengan diagnosis radiologi stroke infark, lokasi infark yang paling banyak muncul adalah terdapat pada daerah parietal dextra. Kata kunci: CT Scan, Stroke Infark, Parietal Dextra.

scholarly journals Electric myocardial inhomogeneity and stroke: connection and specifics

2021 ◽  
Vol 20 (Supplement_1) ◽  
Author(s):  
R Sharafutdinova ◽  
VI Ruzov ◽  
RH Gimaev ◽  
DY Skvortsov ◽  
PV Belogubov
Keyword(s):  
Ischemic Stroke ◽  
Hemorrhagic Stroke ◽  
Right Hemisphere ◽  
Qt Dispersion ◽  
Electrical Stability ◽  
Hemispheric Stroke ◽  
Funding Sources ◽  
Electrical Instability ◽  
The Right ◽  
Funding Acknowledgements

Abstract Funding Acknowledgements Type of funding sources: None. Background. The inconsistency of the literature data on the influence of different hemispheric localization of Cerebrovascular accident (CVA) on the development of cardiac arrhythmias suggests the expediency of further study of the so-called "zones" of the cerebral cortex associated with electrical instability of the myocardium.  It is known that dispersion of QT interval and fragmented myocardial activity belong to the markers of electrical instability of the heart and are associated with arrhythmogenesis.  The aim of the study.  To study the severity of abnormalities of the parameters of electrical instability of myocardium in right and left hemispheric stroke localization in patients with hypertension. Material and methods. 111 patients with left hemispheric localization of ischemic stroke and 75 patients with right hemispheric stroke were examined. Hemorrhagic stroke was observed in 17 patients in the left hemisphere and in 13 patients in the right hemisphere. The average age was 58,2 ± 7,48 years. For all strokes, men prevailed (64% vs. 36%). For the first day of the stroke, all patients were evaluated for QT dispersion and fragmented myocardial activity on the device "Polyspectro-8EX" (Russia).  Research results.  Evaluation of the parameters of electrical instability of myocardium in patients with stroke revealed more pronounced disorders in hemorrhagic stroke of left hemispheric localization (Table 1). In ischemic stroke, the severity of electrophysiological parameters, reflecting the instability of the myocardium depending on the hemispheric localization, indicates the absence of differences.  Conclusions.  1.The most pronounced disturbances in the parameters of electrical stability of the myocardium is observed in hemorrhagic stroke.  2.The severity of myocardial electrical instability in ischemic stroke is not associated with the localization of the focus.

scholarly journals KENASABAN KADAR 8-HYDROXY-2-DEOXYGUANOSINE (8-OHDG) SERUM DENGAN DERAJAT DEFISIT NEUROLOGIS PADA STROK ISKEMIK {Correlation of Serum 8-Hydroxy-2-Deoxyguanosine (8-OHdG) With Neurological Deficits in Ischemic Stroke}

2018 ◽  
Vol 22 (1) ◽  
pp. 55
Author(s):  
Liza Liza ◽  
Ida Parwati ◽  
Andi Basuki Prima Birawa
Keyword(s):  
Oxidative Stress ◽  
Ischemic Stroke ◽  
Serum Concentration ◽  
Ct Scan ◽  
Acute Ischemic Stroke ◽  
Structural Damage ◽  
Clinical Symptoms ◽  
Neurological Deficits ◽  
Positive Correlation ◽  
The Brain

The brain blood flow blockage in ischemic stroke increased oxidative stress and free radicals that cause neurotic cells damage.Computed Tomography Scanning (CT scan) assesses the brain structural damage but not the brain cells damage quantitatively. Adiscrepancy between CT scanand clinical symptoms of ischemic stroke patient is often found. 8-Hydroxy-2-Deoxyguanosine (8-OHdG)serum concentrationis the result offree radical interaction with the cluster C8guanine bases, was used to assess the degree ofneuron cellsdamage, oxidative stress levels. Increase of 8-OHdG serum concentration indicates brain cellsdamage as reflected in the neurologicaldeficitsby the The National Institutes of Health Stroke Scale (NIHSS). The aim of this study was to know the correlation of 8-OHdG serumconcentration with the determination of the degree of neurological deficitby NIHSS inischemic stroke patients. Seventy-two patients withacute ischemic stroke were enrolled in the Dr. Hasan Sadikin Hospital from August 2013 to January 2014. The research was carriedout by cross sectional study design. Statistical analysis was performed by Kruskal-Wallis test, rank Spearman’s correlation test. Mildneurological deficit with a median of 8-OHdG serum concentrations was 3.9 ng/mL (3.3−12.0 ng/mL), moderate neurological deficitwas 23 ng/mL (8.0−51.0 ng/mL) and the severe neurological deficit was 77.5 ng/mL (54.0−97.0 ng/mL). The correlation of 8-OHdGserum concentration with neurological deficits in acute ischemic stroke was 0.912 (p<0.001. Correlation of serum 8-OHdG concentrationwith neurological deficits in acute ischemic stroke was 0.912 (p<0.001). Based on this study result it can be concluded, that this researchhas a strong meaningful positive correlation of 8-OHdG serum concentration with neurological deficits as examined by NIHSS. Inconclusion, serum 8-OHdG has a strong meaningful positive correlation with neurological deficits. 8-OHdG serum concentration can beconsidered to be used to assess discrepancy between CT scan and clinical symptoms as well in health facilities without CT scan.

scholarly journals Is Lateropulsion Really Related with a Specific Lesion of the Brain?

2021 ◽  
Vol 11 (3) ◽  
pp. 354
Author(s):  
Kyoung Lee ◽  
Sang Yoo ◽  
Eun Ji ◽  
Woo Hwang ◽  
Yeun Yoo ◽  
...  
Keyword(s):  
Right Hemisphere ◽  
Parietal Lobe ◽  
Inferior Frontal Gyrus ◽  
Brain Lesions ◽  
Vertical Posture ◽  
Lesion Volume ◽  
Precentral Gyrus ◽  
Stroke Patients ◽  
The Right ◽  
Right Hemisphere Stroke

Lateropulsion (pusher syndrome) is an important barrier to standing and gait after stroke. Although several studies have attempted to elucidate the relationship between brain lesions and lateropulsion, the effects of specific brain lesions on the development of lateropulsion remain unclear. Thus, the present study investigated the effects of stroke lesion location and size on lateropulsion in right hemisphere stroke patients. The present retrospective cross-sectional observational study assessed 50 right hemisphere stroke patients. Lateropulsion was diagnosed and evaluated using the Scale for Contraversive Pushing (SCP). Voxel-based lesion symptom mapping (VLSM) analysis with 3T-MRI was used to identify the culprit lesion for SCP. We also performed VLSM controlling for lesion volume as a nuisance covariate, in a multivariate model that also controlled for other factors contributing to pusher behavior. VLSM, combined with statistical non-parametric mapping (SnPM), identified the specific region with SCP. Lesion size was associated with lateropulsion. The precentral gyrus, postcentral gyrus, inferior frontal gyrus, insula and subgyral parietal lobe of the right hemisphere seemed to be associated with the lateropulsion; however, after adjusting for lesion volume as a nuisance covariate, no lesion areas were associated with the SCP scores. The size of the right hemisphere lesion was the only factor most strongly associated with lateropulsion in patients with stroke. These results may be useful for planning rehabilitation strategies of restoring vertical posture and understanding the pathophysiology of lateropulsion in stroke patients.

Sign in / Sign up

Export Citation Format

Share Document