scholarly journals Thyroidectomy in patients with amiodarone-induced thyrotoxicosis

2021 ◽  
Vol 180 (2) ◽  
pp. 42-49
Author(s):  
U. A. Tsoy ◽  
A. A. Shekhovtsova ◽  
E. V. Ivanikha ◽  
M. A. Salov ◽  
I. N. Danilov ◽  
...  
Keyword(s):  
Intraoperative Complications ◽  
Arrhythmogenic Right Ventricular Dysplasia ◽  
Left Ventricular ◽  
Early Postoperative Period ◽  
Functional Class ◽  
Long Term Results ◽  
Left Ventricular Ejection ◽  
Ventricular Ejection Fraction ◽  
Cardiac Pathology

The OBJECTIVE of the study was to analyze the experience of performing thyroidectomy (TE) in patients with amiodarone-induced thyrotoxicosis (AmIT) at our centre.METHODS AND MATERIALS. The study included 12 patients with AmIT who underwent TE. Medical records were analyzed to assess the features of the AmIT and indications for TE. We also studied the operation protocols and postoperative follow-up data. Intraoperative, early and long-term postoperative complications were recorded. The long-term TE results were evaluated by the dynamics of the left ventricular ejection fraction (LVEF) based on the echocardiography data.RESULTS. The main indications for TE included the resistance of thyrotoxicosis to medication and worsening of the cardiac pathology. No cases of thyrotoxicosis progression or thyrotoxic crisis were registered during the operation. The vocal cord paresis developed in one case, completely restored in a year. Blood loss was minimal in all cases. Other intraoperative complications were absent. Not a single death was registered in the early postoperative period. At this period, a short paroxysm of atrial fibrillation resolved on its own was registered in patient with arrhythmogenic right ventricular dysplasia. A patient with biventricular chronic heart failure of a high functional class died 39 days after the operation due to a massive pulmonary thromboembolism. The long-term results of TE were evaluated in eight patients. In four out of five patients with initially reduced LVEF, it increased. In three patients with initially normal LVEF, it did not change.CONCLUSION. Thyroidectomy is an effective and safe treatment in patients with AmIT, including those with the persistent thyrotoxicosis and severe cardiac pathology. The success is possible when the preparation of patients for the intervention is carried out by a team of specialists experienced in treating of such patients.

Abstract 2991: Percutaneous Vs Surgical Revascularization For Multi-vessel Coronary Artery Disease: A Single Center 10 Year Follow-up Of Sos Trial Patients.

Circulation ◽  
2007 ◽  
Vol 116 (suppl_16) ◽  
Author(s):  
Pawel E Buszman ◽  
Szymon Wiernek ◽  
Radoslaw Szymanski ◽  
Bozena Bialkowska ◽  
Piotr P Buszman ◽  
...  
Keyword(s):  
Systolic Function ◽  
Myocardial Revascularization ◽  
Left Ventricular ◽  
Wilcoxon Test ◽  
Long Term Results ◽  
Left Ventricular Ejection ◽  
Term Survival ◽  
Ventricular Ejection Fraction

Aim: The aim of the study was to evaluate PCI and CABG long-term results in patients with multivessel disease during 8–10 years observation based on the CCS scale, vital status and left ventricular ejection fraction (LVEF). Materials and methods: The analysis involved 100 patients, who were randomized to SOS study (PCI-49; CABG-51) in 1997–2000 in the Silesian Heart Center, Katowice, Poland. There was no difference between both groups according to the basic demographic and angiographic data. The average time of observation was 8,4 ± 0,85 years. Echocardiography was performed four times in each patient: before and after the procedure, 3–4 years later and last time 8–10 years after the procedure. Stenocardia was assessed in accordance with the CCS classification. Results: During nearly 10 years follow-up there was 9 deaths in the PCI group (18%, 4 cardiac -8%) and 8 deaths in the CABG group (16%, 4 cardiac, 8%) (F-Cox-test: p=ns for all cause mortality and cardiac death). LVEF and intensification of stenocardia estimated based on CCS classification were not statistically different between both groups at the end of observation. However, in PCI group LVEF increased significantly (p=0,03), while in CABG group it was unchanged. In both groups improvement of symptoms after revascularization was maintained during the follow-up (Wilcoxon test: p<0.001) but it was achieved with repeat revascularization, which was more frequent in PCI group (30 vs 6%, p=0.003). Conclusions: Long-term results demonstrate that both methods of the myocardial revascularization are equal in terms of long-term survival, release of angina and preservation of left ventricular systolic function.

P969Improvement of left ventricular ejection fraction in the first week post rhythm restoration as a marker of long-term recovery of arrhythmia-induced cardiomyopathy in a latin american population

EP Europace ◽  
2020 ◽  
Vol 22 (Supplement_1) ◽  
Author(s):  
J L Laso Bayas ◽  
R Ibarra Castillo ◽  
J L Arbaiza Simon ◽  
M Peralta Coronel
Keyword(s):  
Left Ventricular Ejection Fraction ◽  
Latin American ◽  
Systolic Dysfunction ◽  
Left Ventricular ◽  
Functional Class ◽  
Rhythm Control ◽  
Left Ventricular Ejection ◽  
Ventricular Ejection Fraction ◽  
One Year

Abstract Introduction The incidence of Arrhythmia-Induced Cardiomyopathy (AIC) is presumed to be between 8% and 34%. Its outcome is also not well known and may be linked to multiple factors. However, it has been suggested that a 25% improvement of the Left Ventricular Ejection Fraction (LVEF), during the first week after rhythm restoration could be an indicator of long-term and complete recovery. This fact has not been studied in our country or even in Latin America. Purpose To observe the behavior of the LVEF after restoration of sinus rhythm in patients with systolic dysfunction presumably secondary to AIC, at least in one year of follow-up. Methods We evaluated all patients referred for arrhythmia treatment and having any degree of systolic dysfunction (LVEF less or equal to 50%) and functional class deterioration between January 2015 and September 2018. Restoration of sinus rhythm was accomplished in either by pharmacologic or invasive methods aimed to specific arrhythmias. After the treatment, we proceed with the systolic function evaluation starting one week after rhythm control, and then at one, three, six and twelve months. This evaluation consisted in clinical examination, echocardiographic determination of LVEF, as well as NT-ProBNP and troponin measurements. Results We identified twenty one cases with presumed AIC. Sixteen cases were secondary to atrial flutter, with four others being secondary to atrial fibrillation, and the last one being a consequence of frequent ventricular extrasystoles (VES). Fifteen patients (74%) were male, mean age was 51 years old (4-76 years). All cases of tachycardia had a ventricular rate over 100 beats per minute. The patient with VES, had a 58% burden of ectopic beats. Eighteen of these patients were taken to invasive electrophysiological study and radiofrequency ablation; and three patients received antiarrhythmics as rhythm control strategy. All patients had mid-range to severe systolic dysfunction prior to treatment, with a mean LVEF of 38%±7,5%; 63% of them were in NYHA class III-IV. One week after rhythm restoration, mean LVEF was 54± 6,36%. That was an improvement of 45% in LVEF. Mean LVEF at one and three months was 63± 5,43%, 61± 5,23% at six months and 63± 5,43% at one year. All patients improved their functional class, to NYHA I at the first evaluation post rhythm restoration. We found no differences between troponin and NT-ProBNP levels before and after treatment, except for one patient . Conclusion Appropriately treated AIC seems to have a good prognosis and short-term recovery of LVEF could be a useful indicator of complete normalization in the long-term. To our knowledge, here we detail the results of a relatively large time-series of AIC, and is perhaps the first study in the Latin American region that suggests that early LVEF improvement could predict AIC recovery, but controlled trials should be done in order to confirm these results.

P3691Intra-aortic balloon counterpulsation in takotsubo syndrome complicated by cardiogenic shock: short- and long-term results from a cohort of 2250 patients of the German-Italian-Spanish registry

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
F Santoro ◽  
I.-J Nunez-Gil ◽  
T Stiermaier ◽  
I El-Battrawy ◽  
F Guerra ◽  
...  
Keyword(s):  
Cardiogenic Shock ◽  
Left Ventricular ◽  
Long Term Results ◽  
Left Ventricular Ejection ◽  
Takotsubo Syndrome ◽  
Ventricular Ejection Fraction ◽  
Long Term Follow Up ◽  
Short And Long Term

Abstract Background Takotsubo syndrome (TTS) is featured by an acute and reversible left ventricular dysfunction and can be complicated by cardiogenic shock. Intra-aortic balloon pumping (IABP) use in this setting is controversial, and few data are available from large populations. Aim of this study was therefore to evaluate short- and long-term impact of IABP on mortality in TTS complicated by cardiogenic shock. Methods The GEIST registry is a multicenter, international registry on TTS involving 38 centers from Germany, Italy and Spain. Between 2006 and 2017, 2250 consecutive patients with TTS were enrolled. Results Of the 2250 patients, 211 (9%) experienced cardiogenic shock during hospitalization for TTS. Admission left ventricular ejection fraction (LVEF) was 30±15% and systolic blood pressure was 90±35 mmHg. Apical ballooning pattern was found in 77%, mid-ventricular/basal pattern in 11%, and 2% of the patients, respectively. Forty-two patients out of 211 (19%) received IABP after coronary angiography. Patients receiving IABP compared to standard medical therapy did not differ in terms of age, gender, cardiovascular risk factors and admission LVEF. No differences were found in term of in-hospital mortality (9.5% vs 17% p=0.35), length of hospitalization (19.3 vs 16.3 days p=0.34), need of invasive ventilation (35% vs 41% p=0.60), stroke (4.7% vs 11% p=0.17) and LV thrombus (0.5% vs 1.7%, p=0.98). At long-term follow-up, with a median of 2 years, overall mortality in patients with cardiogenic shock and TTS was 34.1%. Mortality was not different between the IABP and the control group (33.7% vs 35.0%; p=0.85). Conclusions In this large multicenter observational registry, the use of IABP has no impact on mortality at short and long-term follow-up. Further studies are needed to evaluate the best therapeutic strategy in TTS complicated by cardiogenic shock.

scholarly journals The possibilities of using levosimendan in medical preparation to Coronary Artery Bypass Grafting in coronary artery disease patients with low left ventricular ejection fraction

2020 ◽  
Vol 92 (1) ◽  
pp. 43-48
Author(s):  
V P Gazizova ◽  
E E Vlasova ◽  
E V Dzybinskaya ◽  
V V Gramovich ◽  
O V Stukalova ◽  
...  
Keyword(s):  
Heart Failure ◽  
Coronary Artery ◽  
Artery Bypass ◽  
Left Ventricular ◽  
Early Postoperative Period ◽  
Left Ventricular Ejection ◽  
Drug Preparation ◽  
Ventricular Ejection Fraction ◽  
Artery Disease

Aim: to work out an approach of preoperative drug preparation for CAD patients with low LVEF and varying degrees of compensation for CHF, to study the possibility of using levosimendan (L) in this preparation. Materials and methods. We studied 82 patients with severe angina pectoris, multivascular coronary disease, extensive postinfarction zone, LVEF ≤35%, chronic heart failure and proven viable myocardium, which performed CABG. All patients received long - term standard CHF therapy before surgery: loop diuretic, ACE/ARA, beta - blocker, aldosterone antagonist. In the first, retrospective part of the study (39 pts), it was determined which factors could be associated with perioperative AHF. In the second, prospective part (43 pts), the course of the operation and the early postoperative period in patients with compensated and uncompensated heart failure were compared; uncompensated pts received L 2 days before surgery in addition to standard therapy. The third, retro - prospective part of the study (37 pts) was the assessment of operation outcome in patients only with uncompensated pre - operative CHF, but with different preoperative drug preparation. Results. Statistically significant direct influence on the perioperative AHF development was provided by the combined clinical sign - venous pulmonary congestion+orthopnea (p

scholarly journals Results of percutaneous coronary interventions in patients with dysfunctional myocardium.

2018 ◽  
Vol 96 (8) ◽  
pp. 762-768
Author(s):  
Ya. Rustamova ◽  
G. Imanov ◽  
V. Azizov
Keyword(s):  
Left Ventricular Ejection Fraction ◽  
Ejection Fraction ◽  
Stress Echocardiography ◽  
Left Ventricular ◽  
Functional Class ◽  
Viable Myocardium ◽  
Left Ventricular Ejection ◽  
Control Group ◽  
Ventricular Ejection Fraction

Aim: to evaluate immediate and long-term results of endovascular treatment of patients with dysfunctional viable myocardium. Material and methods. 220 patients were included in the study and were divided into 2 groups. The main group (n=138) included patients with proven ischemia and the presence of viable myocardium in the post-MI zone, on account of which they performed endovascular intervention on the arteries that supply the viable myocardium. The control group (n=82) was formed retrospectively and included patients who were on optimal medical therapy, with invasive diagnostics and endovascular treatment not performed by such patients. The viability of the myocardium was determined by the methods ofMRI of the heart with delayed contrast and the method of stress echocardiography with dobutamine. Inclusion criteria: angina pectoris II-IV functional class (CCS); the presence of proven myocardial ischemia according to stress tests; occlusion or subtotal stenosis of one or more coronary arteries according to digital angiography (SYNTAX score <32); presence of segments with disturbed local contractility of left ventricular myocardium; presence of a viable myocardium in the zone of the occluded / stenotic artery; circulatory failure of I-III functional class (NYHA); left ventricular ejection fraction (LVEF) less than 50%. Results. The magnetic resonance imaging (RMI) with delayed contrasting at the preoperative stage allows to reliably estimate the existing violations of local contractility in the zone of the hibernated myocardium, in comparison with the method of stress echocardiography with dobutamine. After 12 and 18 months of follow-up, there was a significant increase in the incidence of non-fatal MI in the control group. In all patients in the long-term period after PCI completion, a significant increase in the left ventricular ejection fraction and an improvement in the local contractility of the myocardium are noted. Among patients who underwent MRI of the heart, it was possible to detect a significant decrease in the mass fraction of ischemic myocardium in the post-MI zone. There was a strong positive correlation (r = 0.54, p<0.05) between the duration of myocardial hibernation and the timing of restoration of its function after PCI. Conclusion. PCI performance in patients with dysfunctional viable myocardium is highly effective, compared with patients receiving only medication. The method of MRI of the heart with delayed contrast allows judging more objectively the dynamics Оригинальные исследования of the restoration of the function of the hibernated viable myocardium and remodeling of the heart after the revascularization, in comparison with stress echocardiography with dobutamine.

scholarly journals The Impact of Age on Clinical Outcomes of Coronary Artery Bypass Grafting: Long-Term Results of a Real-World Registry

2017 ◽  
Vol 2017 ◽  
pp. 1-11 ◽  
Author(s):  
Francesco Nicolini ◽  
Daniela Fortuna ◽  
Giovanni Andrea Contini ◽  
Davide Pacini ◽  
Davide Gabbieri ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Older Patients ◽  
Left Ventricular ◽  
Adverse Outcomes ◽  
Long Term Results ◽  
Left Ventricular Ejection ◽  
Term Survival ◽  
Ventricular Ejection Fraction ◽  
The Impact

The aim of this retrospective multicenter registry study was to investigate age-dependent trends in mortality, long-term survival, and comorbidity over time in patients who underwent isolated CABG from 2003 to 2015. The percentage of patients < 60 years of age was 18.9%. Female sex, chronic pulmonary disease, extracardiac arteriopathy, and neurologic dysfunction disease were significantly less frequent in this younger population. The prevalence of BMI ≥ 30, previous myocardial infarction, preoperative severe depressed left ventricular ejection fraction, and history of previous PCI were significantly higher in this population. After PS matching, at 5 years, patients < 60 years of age reported significantly lower overall mortality (p<0.0001), cardiac-related mortality (p<0.0001), incidence of acute myocardial infarction (p=0.01), and stroke rates (p<0.0001). Patients < 60 years required repeated revascularization more frequently than older patients (p=0.05). Patients < 60 who underwent CABG had a lower risk of adverse outcomes than older patients. Patients < 60 have a different clinical pattern of presentation of CAD in comparison with more elderly patients. These issues require focused attention in order to design and improve preventive strategies aiming to reduce the impact of specific cardiovascular risk factors for younger patients, such as diet, lifestyle, and weight control.

scholarly journals Long-Term Efficacy and Impact on Mortality of Remote Magnetic Navigation Guided Catheter Ablation of Ventricular Arrhythmias

2021 ◽  
Vol 10 (20) ◽  
pp. 4695
Author(s):  
Denise Guckel ◽  
Sarah Niemann ◽  
Marc Ditzhaus ◽  
Stephan Molatta ◽  
Leonard Bergau ◽  
...  
Keyword(s):  
Left Ventricular ◽  
Long Term Results ◽  
Left Ventricular Ejection ◽  
Magnetic Navigation ◽  
Premature Ventricular Contractions ◽  
Ventricular Ejection Fraction ◽  
Remote Magnetic Navigation ◽  
Term Efficacy ◽  
Increased Risk

Remote magnetic navigation (RMN) facilitates ventricular arrhythmia (VA) ablation. This study aimed to evaluate the long-term efficacy of RMN-guided ablation for ventricular tachycardia (VT) and premature ventricular contractions (PVC). A total of 176 consecutive patients (mean age 53.23 ± 17.55 years, 37% female) underwent VA ablation for PVC (132 patients, 75%) or VT (44 patients, 25%). The cohort consisted of 119 patients (68%) with idiopathic VA, 31 (18%) with ischemic (ICM), and 26 (15%) with dilated cardiomyopathy (DCM). VA recurrence was observed in 69 patients (39%, mean age 51.71 ± 19.91 years, 23% female) during a follow-up period of 5.48 years (first quartile 770.50 days, second quartile 1101.50 days, third quartile 1615.50 days). Left ventricular ejection fraction <40% lead to a significantly increased risk for VA (p = 0.031*). Multivariate analyses found DCM to be an independent predictor (IP) for VA recurrence (p < 0.001*, hazard ratio (HR) 3.74, confidence interval (CI) 1.58–8.88). ICM resulted in a lower increase in VA recurrence (p = 0.221, HR 1.49, CI 0.79–2.81). Class I/III/IV antiarrhythmic drug therapy (AADs) was also identified as IP for recurrence (p = 0.030*, HR 2.48, CI 1.11–5.68). A total of 16 patients (9%) died within the observational period. RMN-guided ablation of VA lead to acceptable long-term results. An impaired LV function, DCM, and AADs were associated with a significant risk for VA recurrence. Personalized paths are needed to improve efficacy and outcome.

EARLY OUTCOME AFTER AORTIC VALVE REPLACEMENT ON PATIENTS WITH REDUCED LEFT VENTRICULAR EJECTION FRACTION

2014 ◽  
pp. 31-36
Author(s):  
Quang Thuu Le
Keyword(s):  
Septal Defect ◽  
Intraoperative Complications ◽  
Systolic Pressure ◽  
Atrioventricular Septal Defect ◽  
Left Ventricular ◽  
Left Ventricular Ejection ◽  
Mitral Insufficiency ◽  
Atrioventricular Valve ◽  
Ventricular Ejection Fraction ◽  
Mitral Incompetence

Background: To evaluate the early results of operation for partial atrioventricular septal defect. Methods: Twenty-sevent patients underwent surgical correction of partial atrioventricular septal defect from 1/2011 to 12/2013 at Cardiovascular Centre of Hue Central Hospital. There were 7 (25.9%) female patients and 20 (74.1%) male patients, 18.5% of patients aged < 1 age, 55.6% of patients aged ≥ 1 to 15 years, and 25.9% of patients aged ≥ 16 to 60 years. Sevent (25.9%) had congestive heart failure. There was a primum atrial septal defect in 100% of patients. A cleft of the anterior mitral leaflet was diagnosed in 100% of patients. 92.6% of patients had either moderate or severe mitral incompetence prior to operation. The pulmonary artery systolic pressure exceeded 40 mmHg in 85,.2% of patients. Results: Atrial septal defects were closed with a pericardial patch in 100% of patients. The cleft in its anterior leaflet was closed in 100% of patients. Postoperatively, moderate mitral insufficiency developed in 14.8% of patients. 85.2% of patients have mild mitral incompetence. One patients (3.7%) needed a permanent pacemaker. There was no intraoperative mortality. At 6-9 months postoperatively, left atrioventricular valve insufficiency was moderate in 2 (7.4%) patients and mild in 25 (92.6%) patients who had had cleft closure alone. Conclusions: Repair of partial atrioventricular septal defect is safe and good. It is important to close the cleft in the left atrioventricular valve. The mitral valve should be repaired in a conservative manner. Intraoperative complications occur but are uncommon, suggesting that short-term follow is excellent.

scholarly journals Systolic blood pressure and outcome in patients admitted with acute heart failure: a pooled analysis from 4 randomized clinical trials

2021 ◽  
Vol 10 (Supplement_1) ◽  
Author(s):  
J Grand ◽  
K Miger ◽  
A Sajadieh ◽  
L Kober ◽  
C Torp-Pedersen ◽  
...  
Keyword(s):  
Heart Failure ◽  
Composite Endpoint ◽  
Left Ventricular ◽  
Left Ventricular Ejection ◽  
Term Outcome ◽  
Ventricular Ejection Fraction ◽  
Long Term Outcome ◽  
All Cause Mortality ◽  
Short And Long Term

Abstract Funding Acknowledgements Type of funding sources: Foundation. Main funding source(s): The Danish Heart Foundation Background In acute heart failure (AHF), low systolic blood pressure (SBP) has been associated with poor outcome. Less is known of the risk related to normal versus elevated SBP and interaction with left ventricular ejection fraction. Purpose The aim of the present study was to assess the association between baseline SBP and short- and long-term outcome in a large cohort of AHF-patients. Methods A pooled cohort of four randomized controlled trials investigating the vasodilator serelaxin versus placebo in patients admitted with AHF and an SBP from 125 to 180 mmHg. Endpoints were 180-day all-cause mortality and a short-term composite endpoint (worsening heart failure, all-cause mortality or hospital readmission for HF through Day 14). Left ventricular ejection fraction (LVEF) was categorized into HFrEF (&lt;40%) and HFpEF (= &gt;40%). Multivariable Cox regression was used and adjusted for age, sex, baseline body mass index, HFrEF, serum estimated glomerular filtration rate, allocated treatment (placebo/serelaxin), diabetes mellitus, ischemic heart disease, and atrial fibrillation/flutter. Measurements and Main Results A total of 10.533 patients with a mean age of 73 (±12) years and median SBP of 140 (130-150) mmHg were included within mean 8.2 hours from admission. LVEF was assessed in 8493 (81%), and of these, 4294 (51%) had HFrEF. Increasing SBP as a continuous variable was inversely associated with 180-day mortality (HRadjusted: 0.93 [0.88-0.98], p = 0.004 per 10 mmHg increase) and with the composite endpoint (HRadjusted: 0.90 [0.85-0.95], p &lt; 0.0001 per 10 mmHg increase). A significant interaction was observed regarding LVEF, revealing that SBP was not associated with mortality in patients with HFpEF  (HRadjusted: 1.01 [0.94-1.09], p = 0.83 per 10 mmHg increase), but SBP was associated with increased mortality in HFrEF (HRadjusted: 0.80 [0.73-0.88], p &lt; 0.001 per 10 mmHg increase) (Figure). Conclusions Elevated SBP is independently associated with favorable short- and long-term outcome in AHF-patients. The association between SBP and mortality was, however, not present in patients with preserved LVEF. Abstract Figure. Survival plots by SBP and LVEF

scholarly journals Electrical storm reveals worse prognosis compared to myocardial infarction complicated by ventricular tachyarrhythmias in ICD recipients

2021 ◽  
Author(s):  
Julian Müller ◽  
Michael Behnes ◽  
Tobias Schupp ◽  
Dominik Ellguth ◽  
Gabriel Taton ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Left Ventricular ◽  
Left Ventricular Ejection ◽  
Electrical Storm ◽  
Ventricular Tachyarrhythmias ◽  
Ventricular Ejection Fraction ◽  
St Segment ◽  
All Cause Mortality ◽  
Worse Prognosis

AbstractBoth acute myocardial infarction complicated by ventricular tachyarrhythmias (AMI–VTA) and electrical storm (ES) represent life-threatening clinical conditions. However, a direct comparison of both sub-groups regarding prognostic endpoints has never been investigated. All consecutive implantable cardioverter-defibrillator (ICD) recipients were included retrospectively from 2002 to 2016. Patients with ES apart from AMI (ES) were compared to patients with AMI accompanied by ventricular tachyarrhythmias (AMI–VTA). The primary endpoint was all-cause mortality at 3 years, secondary endpoints were in-hospital mortality, rehospitalization rates and major adverse cardiac event (MACE) at 3 years. A total of 198 consecutive ICD recipients were included (AMI–VTA: 56%; ST-segment elevation myocardial infarction (STEMI): 22%; non-ST-segment myocardial infarction (NSTEMI) 78%; ES: 44%). ES patients were older and had higher rates of severely reduced left ventricular ejection fraction (LVEF) < 35%. ES was associated with increased all-cause mortality at 3 years (37% vs. 19%; p = 0.001; hazard ratio [HR] = 2.242; 95% CI 2.291–3.894; p = 0.004) and with increased risk of first cardiac rehospitalization (44% vs. 12%; p = 0.001; HR = 4.694; 95% CI 2.498–8.823; p = 0.001). This worse prognosis of ES compared to AMI–VTA was still evident after multivariable adjustment (long-term all-cause mortality: HR = 2.504; 95% CI 1.093–5.739; p = 0.030; first cardiac rehospitalization: HR = 2.887; 95% CI 1.240–6.720; p = 0.014). In contrast, the rates of MACE (40% vs. 32%; p = 0.326) were comparable in both groups. At long-term follow-up of 3 years, ES was associated with higher rates of all-cause mortality and rehospitalization compared to patients with AMI–VTA.

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