scholarly journals Vitamin D levels, vitamin D receptor polymorphisms and HOMA2 model in Cuban Americans, Haitian Americans, and African Americans with and without type 2 Diabetes

2012 ◽  
Author(s):  
Lamya Shaban
Keyword(s):  
Type 2 Diabetes ◽  
Vitamin D ◽  
African Americans ◽  
Vitamin D Receptor ◽  
Vitamin D Levels ◽  
Cuban Americans ◽  
Haitian Americans

scholarly journals Interactions between Serum Vitamin D Levels and Vitamin D Receptor Gene FokI Polymorphisms for Renal Function in Patients with Type 2 Diabetes

PLoS ONE ◽  
2012 ◽  
Vol 7 (12) ◽  
pp. e51171 ◽  
Author(s):  
Keitaro Yokoyama ◽  
Akio Nakashima ◽  
Mitsuyoshi Urashima ◽  
Hiroaki Suga ◽  
Takeshi Mimura ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Vitamin D ◽  
Renal Function ◽  
Vitamin D Receptor ◽  
Receptor Gene ◽  
Serum Vitamin ◽  
Vitamin D Receptor Gene ◽  
Serum Vitamin D ◽  
Vitamin D Levels

scholarly journals Association between Vitamin D Receptor Polymorphisms (BsmI and FokI) and Glycemic Control among Patients with Type 2 Diabetes

2021 ◽  
Vol 18 (4) ◽  
pp. 1595
Author(s):  
Wan Nur Amalina Zakaria ◽  
Nazihah Mohd Yunus ◽  
Najib Majdi Yaacob ◽  
Julia Omar ◽  
Wan Mohd Izani Wan Mohamed ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Vitamin D ◽  
Glycemic Control ◽  
Vitamin D Receptor ◽  
Poor Glycemic Control ◽  
Healthy Controls ◽  
Vdr Gene ◽  
Control Factors ◽  
Vitamin D Levels

(1) Background: Several studies have suggested that the vitamin D receptor (VDR) gene plays a role in type 2 diabetes mellitus (T2DM) susceptibility. Nonetheless, the association between T2DM and VDR polymorphisms remains inconclusive. We determined the genotype of VDR rs1544410 (BsmI) and rs2228570 (FokI) polymorphisms among Malaysian patients with T2DM and their association with glycemic control factors (vitamin D levels, calcium, magnesium, and phosphate). (2) Methods: A total of 189 participants comprising 126 patients with T2DM (63 with good glycemic control and 63 with poor glycemic control) and 63 healthy controls were enrolled in this case–control study. All biochemical assays were measured using spectrophotometric analysis. VDR gene FokI and BsmI polymorphisms were analyzed using polymerase chain reaction and endonuclease digestion. (3) Results: Our findings revealed no significant differences in VDR FokI and BsmI genotypes between participants with T2DM and healthy controls. Moreover, no significant association was observed between both single nucleotide polymorphisms and glycemic control factors. Participants with poor glycemic control had significantly lower serum magnesium levels and significantly higher HOMA-IR compared to the other groups. (4) Conclusions: The present study revealed that VDR gene BsmI and FokI polymorphisms were not significantly associated with T2DM.

scholarly journals Relationship between Microalbuminuria and Serum Vitamin D Levels in African Americans with Type 2 Diabetes

2015 ◽  
Vol 29 (S1) ◽  
Author(s):  
Gustavo Zarini ◽  
Lemia Shaban ◽  
Joel Exebio ◽  
Joan Vaccaro ◽  
Sahar Ajabshir ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Vitamin D ◽  
African Americans ◽  
Serum Vitamin ◽  
Serum Vitamin D ◽  
Vitamin D Levels

scholarly journals Body mass index and serum vitamin D levels in Cuban, African, and Haitian Americans with type 2 diabetes (1029.7)

2014 ◽  
Vol 28 (S1) ◽  
Author(s):  
Fatma Huffman ◽  
Karol Feijao ◽  
Lemia Shaban ◽  
Gustavo Zarini ◽  
Sahar Ajabshir ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Body Mass Index ◽  
Vitamin D ◽  
Body Mass ◽  
Serum Vitamin ◽  
Serum Vitamin D ◽  
Vitamin D Levels ◽  
Haitian Americans

Abstract #421 Association of Vitamin D Levels with the Severity of Fibrosis in NAFLD Patients with Type 2 Diabetes

2019 ◽  
Vol 25 ◽  
pp. 199-200
Author(s):  
Prathyusha Chitrapu ◽  
Shilpa Jain ◽  
Aaron Thrift ◽  
Maya Balakrishnan ◽  
Ruchi Gaba
Keyword(s):  
Type 2 Diabetes ◽  
Vitamin D ◽  
Vitamin D Levels

scholarly journals Reduced Lower-Limb Muscle Strength and Volume in Patients With Type 2 Diabetes in Relation to Neuropathy, Intramuscular Fat, and Vitamin D Levels

Diabetes Care ◽  
2016 ◽  
Vol 39 (3) ◽  
pp. 441-447 ◽  
Author(s):  
Monirah M. Almurdhi ◽  
Neil D. Reeves ◽  
Frank L. Bowling ◽  
Andrew J.M. Boulton ◽  
Maria Jeziorska ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Vitamin D ◽  
Muscle Strength ◽  
Lower Limb ◽  
Intramuscular Fat ◽  
Lower Limb Muscle ◽  
Limb Muscle ◽  
Vitamin D Levels

Association of genetic polymorphisms in vitamin D receptor (ApaI, TaqI and FokI) with vitamin D and glycemic status in type 2 diabetes patients from Southern India

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Sandhiya Selvarajan ◽  
Akila Srinivasan ◽  
Deepanjali Surendran ◽  
Jayanthi Mathaiyan ◽  
Sadishkumar Kamalanathan
Keyword(s):  
Type 2 Diabetes ◽  
Vitamin D ◽  
Southern India ◽  
Glycemic Status ◽  
Genotype Frequencies ◽  
South Indian ◽  
Vitamin D Levels ◽  
Vdr Polymorphisms ◽  
Diabetes Patients

Abstract Objectives To evaluate the association of VDR polymorphisms (FokI, TaqI and ApaI) with vitamin D levels and glycemic status in type 2 diabetes patients from Southern India. Methods In this observational study, genotype frequencies and vitamin D levels of 200 cases (type 2 diabetes patients) were compared with 300 controls (unrelated anonymised stored samples of healthy volunteers) from south India. Serum 25 (OH) D levels were measured by immunoassay technique, glycated hemoglobin (HbA1c) was measured using HPLC and genotyping of VDR polymorphisms were carried out using Real time Polymerase Chain Reaction (RT PCR). Results About 69.2% of type 2 diabetes patients were found to have vitamin D deficiency. FokI polymorphism showed variations in serum 25 (OH) D levels, with AA and AG genotypes having significantly lower serum 25 (OH) D levels as compared to GG [13.24 (8.4) ng/ml, 15.02 (7.07) ng/ml and 20.67 (13.64) ng/ml respectively]. There was no difference in HbA1c levels with respect to the vitamin D levels and VDR polymorphisms. Conclusions AA and AG genotypes of FokI polymorphisms are associated with low serum 25 (OH) D levels. However there was no association between VDR polymorphisms and glycemic status in south Indian type 2 diabetes patients.

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