scholarly journals Comparative Study on Efficacy of Various Types of Exposure Response Prevention Therapies on OCD

2017 ◽  
Vol 4 (2) ◽  
Author(s):  
Mihir Ranjan Nayak ◽  
Narendra nath Samantaray ◽  
Preeti Singh ◽  
Mihir Ranjan Nayak
Keyword(s):  
Comparative Study ◽  
Treatment Outcomes ◽  
Pharmacological Treatment ◽  
Cognitive Restructuring ◽  
Treatment Groups ◽  
Exposure Response ◽  
Exposure Response Prevention ◽  
Management Method ◽  
Exposure Sessions ◽  
Treatment Procedures

Objective: The heterogeneity of OCD has various mixed findings related to the treatment procedures, psychological and pharmacological treatment. Consistent research has shown mixed findings regarding which form of ERP, ERP as Habituation tool or ERP as restructuring tool, is more efficacious. Hence this study is done to examine efficacies of various treatment procedures but importantly to propose a possible treatment choices based on efficacy and acceptability in Indian settings for OCD management. Method: Participants were adult outpatients (N=22) with primary OCD selected  from OPD level and randomly assessed to two treatment groups; a) ERP(Habituation only) with SSRI b) ERP (ERP as restructuring tool) with SSRI. Participants received 12-14 exposure sessions, Result and Conclusions: ERP when used as a process of “habituation” is more efficacious in terms of treatment outcomes but when ERP used as both habituation and cognitive restructuring tool is more tolerable and acceptable by patients and also not prone to dropouts.

Detection of emotional states of OCD patients in an exposure-response prevention therapy scenario

2019 ◽  
Author(s):  
Kaajal Gupta ◽  
Anzar Zulfiqar ◽  
Pushpa Ramu ◽  
Tilak Purohit ◽  
V. Ramasubramanian
Keyword(s):  
Response Prevention ◽  
Emotional States ◽  
Exposure Response ◽  
Prevention Therapy ◽  
Exposure Response Prevention

scholarly journals Fatores preditores de resultados no tratamento do transtorno obsessivo-compulsivo com as terapias comportamental e cognitivo-comportamental: uma revisão sistemática

2008 ◽  
Vol 30 (1 suppl) ◽  
Author(s):  
Andréa Litvin Raffin ◽  
Ygor Arzeno Ferrão ◽  
Fernanda Pasquoto de Souza ◽  
Aristides Volpato Cordioli
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Predictive Factors ◽  
Response Prevention ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Exposure Response ◽  
Exposure Response Prevention

INTRODUÇÃO: As terapias comportamental e cognitivo-comportamental reduzem os sintomas do transtorno obsessivo-compulsivo em mais de 70% dos pacientes. Entretanto, cerca de 30% não obtêm nenhuma melhora. Conhecer fatores associados a esses desfechos poderia auxiliar numa melhor indicação do tratamento, incrementando sua eficácia. MÉTODO: Foram revisados trabalhos que investigaram fatores preditivos de resultados nos tratamentos do transtorno obsessivo-compulsivo, nas fontes PubMed, PsycINFO e LILACS. Termos utilizados na busca: predictive factors OR prediction AND obsessive-compulsive disorder AND exposure response prevention OR ritual prevention OR behav* therapy OR cognitive behav* therapy, resultando em 104 artigos. As referências dos artigos foram analisadas, possibilitando maior número de trabalhos revisados. Excluíram-se artigos que utilizaram apenas farmacoterapia e aqueles que não abordavam o tema, resultando em 29 artigos. DISCUSSÃO: As variáveis demográficas parecem exercer papel indireto, destacando-se sexo masculino e ausência de companheiro(a) como fatores de pior prognóstico. Maior gravidade e início precoce dos sintomas indicariam piores resultados. O transtorno esquizotípico comórbido é potencialmente negativo. Sintomas relacionados ao colecionismo e com conteúdo sexual/religioso indicam pior prognóstico. Maior nível de insight, motivação e colaboração com o tratamento são características favoráveis. Maior intensidade da melhora e a remissão completa são preditores para a não-recaída. CONCLUSÃO: A identificação de fatores preditores de resultados está longe de ser esclarecida. É possível que múltiplos fatores, cujas associações são complexas, atuem em conjunto. Os resultados podem depender de fatores não-específicos, ainda não abordados pelos estudos. A heterogeneidade do transtorno obsessivo-compulsivo e das pesquisas e o uso associado de medicamentos dificultam o estabelecimento de conclusões mais definidas.

scholarly journals Efficacy and Safety of 25% Trichloroacetic Acid Peel Versus 30% Salicylic Acid Peel in Mild-to-Moderate Acne Vulgaris: A Comparative Study

2021 ◽  
pp. 2021063
Author(s):  
Surabhi Dayal ◽  
Satbir Singh ◽  
Priyadarshini Sahu
Keyword(s):  
Salicylic Acid ◽  
Adverse Effects ◽  
Comparative Study ◽  
Clinical Efficacy ◽  
Trichloroacetic Acid ◽  
Acne Vulgaris ◽  
Efficacy And Safety ◽  
Inflammatory Lesions ◽  
Treatment Groups ◽  
Proven Efficacy

Background: Both salicylic acid (SA) and trichloroacetic acid (TCA) have proven efficacy with goodsafety profiles in the treatment of acne vulgaris. Objectives: This study compared the clinical efficacy and safety of 25% TCA and 30% SA peels in thetreatment of mild and moderate acne vulgaris. Methods: Patients with mild or moderate acne vulgaris were randomized into 2 groups of 25 personseach, and treated with either the TCA peel or the SA peel at 2-week intervals for 12 weeks. Evaluationof active acne was done by individual lesion counts (comedones, papules and pustules) and calculationof the Michaelsson acne score (MAS). Results: Both peels led to significant decrease in individual lesion counts and MAS compared to baselinevalues, without significant differences between the treatment groups. Thus, the peels had equivalentefficacy against acne vulgaris. The TCA peel was better in treating non-inflammatory lesions,while the SA peel was better for inflammatory lesions, but the differences were not significant. Noserious adverse effects were recorded, but more patients in the TCA peel group experienced burningand stinging sensations. Conclusion: The efficacy of 25% TCA is comparable to that of 30% SA in mild-to-moderate acnevulgaris, but safety and tolerability were better with the SA peel than TCA peel.

Tissue and endocrine responses to gestrinone and danazol in the treatment of endometriosis

1993 ◽  
Vol 5 (1) ◽  
pp. 103 ◽  
Author(s):  
KL Forbes ◽  
FJ Thomas
Keyword(s):  
Side Effects ◽  
Comparative Study ◽  
Free Fraction ◽  
Effective Alternative ◽  
Treatment Groups ◽  
Alternative Agent ◽  
Similar Range ◽  
Similar Decrease

An open comparative study of gestrinone and danazol in the treatment of endometriosis demonstrated a similar decrease in the extent of active endometriotic deposits, assessed visually following therapy. Biochemical endocrinological changes during therapy with gestrinone showed that basal concentrations of gonadotrophin remained unchanged, oestradiol concentrations varied and the free fraction of testosterone increased. A similar range of side effects was reported in both treatment groups, consisting predominantly of 'androgenic' effects in 10 of 15 women treated with gestrinone and 5 of 12 treated with danazol. The results suggest that gestrinone is an effective alternative agent for the treatment of endometriosis.

Sign in / Sign up

Export Citation Format

Share Document