scholarly journals Fertility Related Quality of Life in Primary Infertile Couples: A Comparative Study from Eastern India

2017 ◽  
Vol 5 (1) ◽  
Author(s):  
Swarnali Bose ◽  
Bharati Roy
Keyword(s):  
Quality Of Life ◽  
Infertile Couple ◽  
Psychological Burden ◽  
Primary Infertility ◽  
Global Quality ◽  
Global Quality Of Life ◽  
The Family ◽  
Related Quality ◽  
Written Informed Consent

Fertility is considered as a marital responsibility in most the communities and a kind of social respectability for couples. The societal and parental pressures for propagation of the family name can also place a psychological burden on the infertile couple and may significantly affect quality of life. The present study aimed to investigate the gender differences in fertility related quality of life in primary infertility. 30 couples with primary infertility were recruited for the study after a written informed consent. Hindi version of FertiQoL was applied to all participants. Males had significantly better emotional, relational, social and global quality of life (QoL) as compared to females. Tolerability to infertility related problems was significantly better in females compared to males. This study found that primary infertility has extensive negative repercussions on the QOL of women as compared to males.

Health-Related Quality of Life in Men With Metastatic Prostate Cancer Treated With Prednisone Alone or Mitoxantrone and Prednisone

1999 ◽  
Vol 17 (6) ◽  
pp. 1654-1654 ◽  
Author(s):  
David Osoba ◽  
Ian F. Tannock ◽  
D. Scott Ernst ◽  
Alan J. Neville
Keyword(s):  
Quality Of Life ◽  
Prostate Cancer ◽  
Metastatic Prostate Cancer ◽  
Life Questionnaire ◽  
Health Related Quality ◽  
Global Quality ◽  
Global Quality Of Life ◽  
Related Quality ◽  
Health Related

PURPOSE: A combination of mitoxantrone plus prednisone is preferable to prednisone alone for reduction of pain in men with metastatic, hormone-resistant, prostate cancer. The purpose of this study was to assess the effects of these treatments on health-related quality of life (HQL). PATIENTS AND METHODS: Men with metastatic prostate cancer (n = 161) were randomized to receive either daily prednisone alone or mitoxantrone (every 3 weeks) plus prednisone. Those who received prednisone alone could have mitoxantrone added after 6 weeks if there was no improvement in pain. HQL was assessed before treatment initiation and then every 3 weeks using the European Organization for Research and Treatment of Cancer Quality-of-Life Questionnaire C30 (EORTC QLQ-C30) and the Quality of Life Module–Prostate 14 (QOLM-P14), a trial-specific module developed for this study. An intent-to-treat analysis was used to determine the mean duration of HQL improvement and differences in improvement duration between groups of patients. RESULTS: At 6 weeks, both groups showed improvement in several HQL domains, and only physicalfunctioning and pain were better in the mitoxantrone-plus-prednisone group than in the prednisone-alone group. After 6 weeks, patients taking prednisone showed no improvement in HQL scores, whereas those taking mitoxantrone plus prednisone showed significant improvements in global quality of life (P = .009), four functioning domains, and nine symptoms (.001 < P < .01), and the improvement (> 10 units on a scale of 0 to100) lasted longer than in the prednisone-alone group (.004 < P < .05). The addition of mitoxantrone to prednisone after failure of prednisone alone was associated with improvements in pain, pain impact, pain relief, insomnia, and global quality of life (.001 < P < .003). CONCLUSION: Treatment with mitoxantrone plus prednisone was associated with greater and longer-lasting improvement in several HQL domains and symptoms than treatment with prednisone alone.

Health-Related Quality of Life (HRQoL) Measurements in Multiple Myeloma Patients Obtained By EORTC QLQ-C30; A Critical Review of Interpreting HRQoL Data in Longitudinal Studies

Blood ◽  
2016 ◽  
Vol 128 (22) ◽  
pp. 540-540 ◽  
Author(s):  
Lene Kongsgaard Nielsen ◽  
Mary Jarden ◽  
Christen Lykkegaard Andersen ◽  
Henrik Frederiksen ◽  
Niels Abildgaard
Keyword(s):  
Quality Of Life ◽  
First Line ◽  
Global Quality ◽  
Hrqol Data ◽  
Global Quality Of Life ◽  
Related Quality ◽  
Eortc Qlq C30 ◽  
Health Related ◽  
Eortc Qlq

Abstract Introduction: Multiple myeloma (MM) patients report more symptoms and more severe symptoms than patients with other hematological malignancies, resulting in reduced health-related quality of life (HRQoL). Because survival is improving in MM patients there is an increased need for focus on HRQoL. The aim of this review was to interpret published longitudinal studies in MM patients according to a difference in HRQoL score, which is perceived as beneficial to the patient. Such criteria for minimal important differences (MID) in HRQoL score has been explored by Kvam et al (Eur J Haematol 2010, 84:345-53) and has been defined by a concensus expert panel (Cocks et al, Eur J Cancer 2012, 48:1713-21). Methods: A literature search was performed May 2016 in PubMed, Embase, PsycINFO and CINAHL. Publications with longitudinal follow-up using the EORTC QLQ-C30 instrument for HRQoL measurement of physical functioning, global quality of life, fatigue or pain were included, and evaluation of mean change from baseline was carried out according to MID as defined by Kvam, and according to minimal, medium and large changes as defined by Cocks. Results: 11 first-line, 3 consolidation, 2 maintenance, 7 relapse studies, and one population-based study were included. In general, large and medium improvements were reported during first-line treatments. During consolidation with autologous hematopoietic stem cell transplantation, temporary large deteriorations were reported, but equalization occurred with even large improvements compared to baseline reportings. Deterioration or no beneficial change in global quality of life or fatigue are reported by the MM patients during relapse treatment. HRQoL data during maintenance therapy are sparse. For summary of results, see Figure 1. Conclusions: Guidelines for interpreting HRQoL changes with definitions of MID have been developed, but consensus is missing. Improvements in HRQoL are far more likely during first-line compared to relapse treatment regimens. The background of these findings should be in focus in future studies and HRQoL measurements should be part of maintenance studies in the future. Disclosures No relevant conflicts of interest to declare.

scholarly journals Changes in Health-Related Quality of Life During Rehabilitation in Patients With Operable Lung Cancer: A Feasibility Study (PROLUCA)

2016 ◽  
Vol 17 (2) ◽  
pp. 388-400 ◽  
Author(s):  
Maja S. Sommer ◽  
Karen Trier ◽  
Jette Vibe-Petersen ◽  
Karl B. Christensen ◽  
Malene Missel ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Mental Health ◽  
Well Being ◽  
Rehabilitation Program ◽  
Health Related Quality ◽  
Global Quality ◽  
Global Quality Of Life ◽  
Related Quality ◽  
Health Related

Introduction: Surgical resection in patients with non–small cell lung cancer (NSCLC) may be associated with significant morbidity, functional limitations, and decreased quality of life. Objectives: The objective is to present health-related quality of life (HRQoL) changes over time before and 1 year after surgery in patients with NSCLC participating in a rehabilitation program. Methods: Forty patients with NSCLC in disease stage I to IIIa, referred for surgical resection at the Department of Cardiothoracic Surgery RT, Rigshospitalet, were included in the study. The rehabilitation program comprised supervised group exercise program, 2 hours weekly for 12 weeks, combined with individual counseling. The study endpoints were self-reported HRQoL (Functional Assessment of Cancer Therapy–Lung, European Organization for Research and Treatment in Cancer–Quality of Life Questionnaire-QLQ-C30, Short-Form-36) and self-reported distress, anxiety, depression, and social support (National Comprehensive Cancer Network Distress Thermometer, Hospital Anxiety and Depression Scale, Multidimensional Scale of Perceived Social Support), measured presurgery, postintervention, 6 months, and 1 year after surgery. Results: Forty patients were included, 73% of whom completed rehabilitation. Results on emotional well-being ( P < .0001), global quality of life ( P = .0032), and mental health component score ( P = .0004) showed an overall statistically significant improvement during the study. Conclusion: This feasibility study demonstrated that global quality of life, mental health, and emotional well-being improved significantly during the study, from time of diagnosis until 1 year after resection, in patients with NSCLC participating in rehabilitation.

scholarly journals Associations of resilience with quality of life levels in adults experiencing homelessness and mental illness: a longitudinal study

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Cilia Mejia-Lancheros ◽  
Julia Woodhall-Melnik ◽  
Ri Wang ◽  
Stephen W. Hwang ◽  
Vicky Stergiopoulos ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Mental Health ◽  
Mental Illness ◽  
Housing First ◽  
Life Outcomes ◽  
Global Quality ◽  
Global Quality Of Life ◽  
Related Quality ◽  
Health Related

Abstract Background Homelessness constitutes a traumatic period that adversely impacts health and quality of life outcomes. The potential mitigating effects of resilience on quality of life levels in people experiencing homelessness are underresearched. This study assesses the longitudinal associations between resilience and quality of life scores among adults experiencing homelessness and mental illness. Methods This study is a secondary analysis of longitudinal data collected over 6 years from participants (N = 575) of the At Home/Chez Soi study on Housing First, Toronto site. Repeatedly measured resilience scores are the primary exposure and repeatedly measured global quality of life scores and mental health-specific quality of life scores are the primary outcomes. Mixed effect models were used to assess the association between the exposures and the outcomes. Results The majority of the participants were men (69.2%) and were on average 40.4 (± 11.8) years old at baseline. The average resilience score ranged between 5.00 to 5.62 over 8 data collection points across the 6-year follow-up period. After adjusting for gender, age, ethno-racial background, Housing First intervention, physical and mental comorbidities, and lifetime homelessness, higher resilience scores were positively associated with higher Global quality of life (Adjusted-coefficient: 0.23, 95% CI 0.19–0.27) and mental health-related quality of life values (Adjusted-coefficient: 4.15, 95% CI 3.35–4.95). Conclusion In homeless adults with mental illness, higher resilience levels were positively associated with higher global and mental health related quality of life values. Further interventions and services aimed to enhance resilience mechanisms and strategies are warranted to enhance better mental health and quality of life outcomes of this population group. Trial registration At Home/Chez Soi trial was registered with ISRCTN, ISRCTN42520374. Registered 18 September 2009, http://www.isrctn.com/ISRCTN42520374.

scholarly journals Associations between psychological factors and health-related quality of life and global quality of life in patients with ALS: a systematic review

2016 ◽  
Vol 14 (1) ◽  
Author(s):  
Annerieke C. van Groenestijn ◽  
Esther T. Kruitwagen-van Reenen ◽  
Johanna M. A. Visser-Meily ◽  
Leonard H. van den Berg ◽  
Carin D. Schröder
Keyword(s):  
Quality Of Life ◽  
Systematic Review ◽  
Psychological Factors ◽  
Health Related Quality ◽  
Global Quality ◽  
Global Quality Of Life ◽  
Related Quality ◽  
Health Related

scholarly journals Measurement of Quality of Life VII. Statistical Covariation and Global Quality of Life Data: The Method of Weight-Modified Linear Regression

2003 ◽  
Vol 3 ◽  
pp. 1020-1029 ◽  
Author(s):  
Soren Ventegodt ◽  
Joav Merrick
Keyword(s):  
Quality Of Life ◽  
Linear Regression ◽  
Scientific Community ◽  
Population Studies ◽  
Life Data ◽  
Global Quality ◽  
Global Quality Of Life ◽  
Psychometric Measures ◽  
Exact Size

Existing standard statistical procedures do not seem to fulfill the needs of the researcher in global quality-of-life (QOL) research, because the most interesting question seems to be the exact size of statistical covariations. A method is necessary if we are to isolate the most important factors connected to quality of life among the thousands of possible factors in life. We have developed a new procedure we call �weight-modified linear regression�. Unfortunately as demonstrated in the discussion, the procedure is not totally without problems and weaknesses. In spite of the critique, we believe the procedure to be valid for the purpose of estimating the size of the covariation in population studies including psychometric measures of global quality of life. As we need to be certain that the procedure is valid, we hereby invite the scientific community to give us further critique of the method and suggestions for its improvement.

scholarly journals Family Burden and Health Related Quality of Life of HIV Infected Individuals in Madurai, South India

2017 ◽  
Vol 13 (1) ◽  
pp. 1-8 ◽  
Author(s):  
E. Thiruvalluvan
Keyword(s):  
Quality Of Life ◽  
Mental Health ◽  
Social Functioning ◽  
Family Burden ◽  
Health Related Quality ◽  
Interview Schedule ◽  
The Family ◽  
Related Quality ◽  
Health Related

Introduction: With the advent of Highly Active Antiretroviral Therapy (HAART) in 1996, HIV-infected patients are living longer and are concerned not only with treatment’s ability to extend their life butalso with the quality of the life they are able to lead, because, efficacy of treatment is strongly relatedto meaningful outcome i.e., better Quality of Life. Especially Health related quality of life has not been studied well. Hence, this study was necessitated with the objectives to evaluate Health Related Quality of Life (HRQoL) in HIV infected persons on ART. The secondary objectives were to assess the family burden experienced by the families of HIV infected, and measure influence of family burden on overall quality of life.Methodology: The HIV infected individuals who were started on treatment six months prior to date of interview were considered for the study The SF36 (Short Form with 36 questions) was used to evaluate function and mental Health while Pai and Kapur’s Family Burden Interview schedule was used to assess family burden. Interview schedule was pre-tested on 10 HIV infected individuals for consistency. Data analysis was performed using SPSS version 11 (SPSS inc. Chicago, IL, USA). Pearson product moment Correlation were computed to explore the relationships of SF36 with SLI, Family Burden and BMI. Further, Independent student “t” – test was performed to see the association between HRQoL and gender.Results: Of 91 participants interviewed 51.6% were women. Median age (years) of the respondents was 33. The overall mean score for Physical health was 45.13 SD (12.40) and for Mental health 56.91 SD (15.52). Age of HIV infected persons had significant influence in scores in social functioning (p-value .015), emotional well being scores (.015), and Mental health (.010). Socio life Index was directly related to physical health, mental health, Vitality, social functioning and emotional scores on HRQoL. Physicalhealth score was negatively affected by the Family burden score. Similarly, BMI status of the respondents correlated with Mental health, Body Pain, Vitality and Role emotional scores of HRQoL scale SF 36.Conclusion: Socio Life Index and BMI appear to be the two important predictors of HRQoL. Therefore, special attention may be required to HIV infected persons with lower SLI and BMI. Nutritional supplements, in addition to ART drugs, may be provided to ensure some improvements in physical functioning.SAARC J TUBER LUNG DIS HIV/AIDS, 2016; XIII(1), Page: 1-8

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