scholarly journals Pair of glomus tumors in thigh – both periosteal and intramuscular: Rare tumor in atypical location

2021 ◽  
Vol 0 ◽  
pp. 1-4
Author(s):  
Debanjan Nandi ◽  
Kiran Madhavrao Zadte ◽  
Ipsita Dhal
Keyword(s):  
Soft Tissue ◽  
Glomus Tumor ◽  
Multimodality Imaging ◽  
Soft Tissue Tumors ◽  
Exceptional Case ◽  
Medial Aspect ◽  
Diagnostic Dilemma ◽  
Left Femur ◽  
Glomus Tumors ◽  
Vastus Medialis Muscle

Glomus tumors are benign neoplasms that arise from neuromyoarterial glomus bodies accounting for <2% of soft-tissue tumors. Glomus tumors represent around 1–5% of all soft-tissue tumors and 1–5% of all hand tumors. About 75% of these tumors occur in hand with 75–90% of these occurring in characteristic subungual location. Extradigital location of glomus tumor is very rare. We report an exceptional case of extradigital glomus tumor causing thigh pain, where there were a pair of lesions both in periosteum and intramuscular location. A 47-year-old male with complaints of pain over medial aspect of the left lower thigh for 2 years on ultrasound revealed well-defined solid hypoechoic lesions within the left vastus medialis muscle and cortical-based lesion abutting the periosteum of distal diaphysis of the left femur on medial aspect. These lesions were hypointense on T1W, hyperintense on T2W and showed early homogenous enhancement on MRI. Histopathology revealed glomus tumors, which commonly occur in digits. Glomus tumors located in both periosteal and intramuscular locations in thigh were in very uncommon. Non-specific presentation with pain in such cases remains a diagnostic dilemma. Role of multimodality imaging and histopathology correlation is important in such situation.

scholarly journals Extradigital Glomus Tumor of Thigh

2015 ◽  
Vol 2015 ◽  
pp. 1-3 ◽  
Author(s):  
Kemal Beksaç ◽  
Lutfi Dogan ◽  
Nazan Bozdogan ◽  
Gulay Dilek ◽  
Gokhan Giray Akgul ◽  
...  
Keyword(s):  
High Temperature ◽  
Soft Tissue ◽  
Glomus Tumor ◽  
Soft Tissue Tumors ◽  
Benign Neoplasms ◽  
Rare Entity ◽  
Glomus Tumors ◽  
Classical Triad ◽  
High Temperature Sensitivity ◽  
Extradigital Glomus

Glomus tumors are benign neoplasms that arise from neuromyoarterial glomus bodies. They represent around 1–5% of all soft-tissue tumors. High temperature, sensitivity, and pain and localized tenderness are the classical triad of symptoms. Most glomus tumors represent in the subungual area of digits. Extradigital glomus tumors are a very rare entity. There are rare cases of these tumors reported to be in shoulder, elbow, knee, wrist, even stomach, colon, and larynx. We are reporting a case of a glomus tumor on thigh and discuss the histological and immunohistochemical features.

Glomus Tumor

2008 ◽  
Vol 132 (9) ◽  
pp. 1448-1452 ◽  
Author(s):  
Zoltan Gombos ◽  
Paul J. Zhang
Keyword(s):  
Soft Tissue ◽  
Glomus Tumor ◽  
Soft Tissue Tumors ◽  
Accurate Assessment ◽  
Arteriovenous Anastomosis ◽  
Glomus Tumors ◽  
Mesenchymal Neoplasm ◽  
Specialized Form ◽  
Actual Prevalence ◽  
Glomus Body

Abstract Glomus tumor is a benign mesenchymal neoplasm comprising less than 2% of soft tissue tumors. It is composed of cells resembling modified smooth muscle cells of the normal glomus body. The glomus body, a thermoregulator, is a specialized form of arteriovenous anastomosis localized in dermal and precoccygeal soft tissue. Although glomus tumors are rare neoplasms, clinical misdiagnosis of many of these lesions as hemangiomas or venous malformations makes an accurate assessment of their actual prevalence difficult. A malignant counterpart of this lesion exists but is extremely rare.

scholarly journals Giant glomus tumor of the knee mimicking soft-tissue sarcoma

2020 ◽  
Vol 2 ◽  
pp. 82-86
Author(s):  
Vikas Batra ◽  
Nafisa Shakir Batta ◽  
Ankur Gupta
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Sarcoma ◽  
Unusual Case ◽  
Glomus Tumor ◽  
Biceps Femoris ◽  
Soft Tissue Tumors ◽  
Vascular Tumors ◽  
Glomus Tumors ◽  
Posterior Knee ◽  
Point Tenderness

Glomangiomas (glomus tumors) are benign vascular tumors commonly located at the distal extremities, are usually subungual lesions, and account for 2% of all soft-tissue tumors. Patients with digital glomus tumors present with hypersensitivity to cold, paroxysmal severe pain, and point tenderness. These tumors are infrequent in the knee area, and when seen are superficial, usually have a diameter of less than 1 cm, which make their radiological diagnosis arduous. We report a noteworthy, unusual case of a large glomus tumor in the popliteal fossa showing biceps femoris infiltration, in a 51-year-old female patient who experienced severe intermittent posterior knee pain for the past 2 years. Magnetic resonance imaging revealed a large popliteal inhomogeneous soft-tissue lesion with irregular margins insinuating the posterolateral musculature mimicking soft-tissue sarcoma. Histopathology revealed a glomus tumor.

scholarly journals Digital Glomus Tumor: Bibliographic Review of the Studies Published over the Past 10 Years

2021 ◽  
Vol 49 (01) ◽  
pp. 046-055
Author(s):  
Victoria Hernández ◽  
Tania Lena ◽  
Eliana Camacho ◽  
Matías Craviotto
Keyword(s):  
Glomus Tumor ◽  
Case Reports ◽  
Low Frequency ◽  
Benign Neoplasm ◽  
Surgical Excision ◽  
Soft Tissue Tumors ◽  
Glomus Tumors ◽  
The Past ◽  
Pubmed Search ◽  
Magnetic Resonance Imaging Mri

AbstractGlomus tumors are a mostly benign neoplasm that constitutes less than 4% of upper-limb soft-tissue tumors. Its unspecific clinical presentation, added to its low frequency, leads to a late diagnosis.The objective of the present study is to update the clinical-paraclinical approach and the surgical technique used in the treatment.We carried out a literature review from 2014 to 2019 on digital glomus tumor in the hand in adult patients using the PubMed search engine.In most of the publications analyzed, the diagnosis was clinical, with a delay of 1 to 10 years. Plain radiography is the most requested study; of the 16 articles reporting its indication, only half evidenced compatible changes. Magnetic resonance imaging (MRI) was requested in 15 articles, presenting normal results in 3 of them. The treatment of choice was surgical excision using a transungual approach. Only 4 articles report recurrence after excision.Although there is diversity in the approach to these tumors, we conclude that the diagnosis is clinical, and the treatment surgical, and there is no consensus regarding the paraclinical indication. The information available comes mainly from case reports, publications that contribute to the generation of evidence for the clinical practice in rare diseases such as this one.

scholarly journals A Rare Case of Glomus Tumor on the Mucosal Surface of Lower Lip

2020 ◽  
Vol 8 ◽  
pp. 232470962093615
Author(s):  
Sara Naji Rad ◽  
Samira Najirad ◽  
Rana Rafiei
Keyword(s):  
Oral Cavity ◽  
Glomus Tumor ◽  
Soft Tissue Tumors ◽  
Mucosal Surface ◽  
Lower Lip ◽  
Glomus Tumors ◽  
Mesenchymal Neoplasms ◽  
Benign Soft Tissue Tumors ◽  
Vascular Neoplasms ◽  
History Of

Glomus tumors are mesenchymal neoplasms derived from glomus bodies with rare presentations in the oral cavity. Glomus tumors present as a purple or pink vascular nodule or papule, sized <1 cm, and imitate vascular neoplasms such as hemangiopericytoma or hemangioma. Glomus tumors represent less than 2% of all benign soft tissue tumors. Only 27 cases of benign glomus tumors with oral cavity involvement have been reported to date. The most-reported oral tumors involved the lips (54.2%), followed by hard palate, gingiva, tongue, and buccal mucosa. The mean age of presentation of the labial glomus tumors is 48.7 years, with no gender predilection, in contrast to the subungual site, which occurs more in females. The etiology of the glomus tumors remains unknown. Subungual glomus tumors present as stabbing pain, cold intolerance, and tenderness of the fingertips, whereas labial glomus tumors mostly present as a painless, small, and slow-growing lesion. Treatment is surgical resection of the tumor. The recurrence rate of labial glomus tumors is unclear. In this article, we present the case of a 62-year-old man with a 2-month history of painless, soft lump on the mucosal surface of the lower left lip. Excisional resection of the tumor was performed in the clinic, and the histopathologic finding was consistent with solid glomus tumor. At 1 year follow-up there was no recurrence.

Glomus Tumor in the Elbow: A Case Report and Review of Histopathological Findings

2020 ◽  
Vol 2 (1) ◽  
pp. 01-04
Author(s):  
Rolanda A. Willacy
Keyword(s):  
Case Report ◽  
Severe Pain ◽  
Rare Case ◽  
Glomus Tumor ◽  
Soft Tissue Tumors ◽  
Cold Sensitivity ◽  
Benign Tumors ◽  
Glomus Tumors ◽  
Histopathological Findings ◽  
Tumors Of The Hand

Glomus bodies are neuromyoarterial apparatuses of the skin, implicated in body temperature control, and may undergo transformation with unregulated hyperplasia of their smooth muscle component. Glomus tumors most commonly occur in the subungual region of the fingers. These benign tumors are rare and constitute 1-5% of soft tissue tumors of the hand and may present as solitary or multiple masses. Solitary glomus tumors present with a classic triad of localized tenderness, severe pain, and cold sensitivity. We report a rare case of glomus tumor in the elbow and a review of the histopathological findings.

scholarly journals Glomus Tumor of the Kidney: Case report

2018 ◽  
Vol 64 (3) ◽  
pp. 126-129
Author(s):  
Edith Dee ◽  
Andrada Loghin ◽  
Tamas Toth ◽  
Adrian Năznean ◽  
Angela Borda
Keyword(s):  
Case Report ◽  
Soft Tissues ◽  
Glomus Tumor ◽  
Smooth Muscle Actin ◽  
Soft Tissue Tumors ◽  
Renal Neoplasm ◽  
Microscopic Appearance ◽  
Glomus Tumors ◽  
Eosinophilic Cytoplasm ◽  
Fibrous Tumor

AbstractIntroduction: Glomus tumors are rare benign mesenchymal neoplasms accounting for only 2% of all types of soft tissue tumors. Commonly located in the peripheral soft tissues, they are most frequently encountered in the subungual areas of fingers and toes, and very rarely in visceral organs due to the absence of glomus bodies. To date, 22 cases of primary renal glomus tumors have been described in the literature, of which 17 benign, with no evidence of recurrence or metastasis, three cases of malignant glomus tumor, and two cases with uncertain malignant potential. Case report: We report the 18th case of a benign glomus tumor of the kidney in a 49-year-old female patient, presenting the microscopic appearance (round, uniform cells with indistinct borders, scant finely granular eosinophilic cytoplasm, round nuclei lacking prominent nucleoli, arranged in solid sheets, accompanied by slit-like vascular spaces), the immunohistochemical profile (tumor cells showed immunoreactivity for smooth muscle actin, vimentin, as well as for CD34; they were negative for AE1/AE3, desmin, HMB-45, S-100 protein, renin, and chromogranin), and the differential diagnosis of this rare entity (juxtaglomerular tumor, angiomyolipoma, hemangioma, epithelioid leyomioma, solitary fibrous tumor, carcinoid tumor, and paraganglioma). Conclusion: Primary renal glomus tumors are rare tumors that radiologically can mimic other mesenchymal renal neoplasm. Accurate diagnosis is based on the microscopic appearance and especially the characteristic immunophenotype.

scholarly journals Case report of middle aged male patient with extra digital glomus tumor visiting dermatology clinic of King Abdul-Aziz Medical City, National Guard Health Affairs, Jeddah, Saudi Arabia, 2018

2019 ◽  
Vol 5 (1) ◽  
pp. 206
Author(s):  
Awadh Alamri ◽  
Marwan Alahmadi ◽  
Mohamed B. Satti ◽  
Amaal F. Alruwaili ◽  
Homaid Alotaibi ◽  
...  
Keyword(s):  
Case Report ◽  
Male Patient ◽  
Glomus Tumor ◽  
National Guard ◽  
Soft Tissue Tumors ◽  
Vascular Neoplasm ◽  
Glomus Tumors ◽  
Dermatology Clinic ◽  
Medical City ◽  
Classical Triad

<p class="abstract">Glomus tumors are rare, benign and vascular neoplasm of the glomus body, account for less than 2% of all soft tissue tumors<strong>. </strong>The most common site is the subungual region of the fingers and toes. Extra digital sites including the forearm are uncommon and usually misdiagnosed as other conditions. Usually the glomus tumors present with the classical triad of severe pain, pinpoint tenderness and clod hypersensitivity. This is a case report study design with detailed history, examination of 54-years-old male patient with a painful nodular lesion in the left forearm, which is misdiagnosed as foreign body granuloma. Elliptical excision relieved the symptoms and histopathologic examination confirmed the diagnosis of glomus tumor.</p>

Atypical Presentation of a Glomus Tumor in the Rearfoot: A Case Report

2020 ◽  
Vol 110 (6) ◽  
Author(s):  
Erin M. Kunz ◽  
Bebu Ram
Keyword(s):  
Case Report ◽  
Soft Tissue ◽  
Glomus Tumor ◽  
Excisional Biopsy ◽  
Clinical Findings ◽  
Cold Sensitivity ◽  
Atypical Presentation ◽  
Glomus Tumors ◽  
Clinical Appearance ◽  
Soft Tissue Masses

Glomus tumors are rare and benign vascular soft-tissue masses commonly found subungually in the foot. A glomus tumor typically manifests with a classic triad of pain, point tenderness, and cold sensitivity. This case report describes an atypical presentation of a glomus tumor in the soft tissue of the rearfoot in a 77-year-old man in the setting of urosepsis. The mass had enlarged progressively for 6 months. Originally misdiagnosed as a hemangioma based on magnetic resonance imaging and clinical appearance, an excisional biopsy was performed. The lesion was subsequently diagnosed histopathologically as a glomus tumor. This article discusses the statistics of glomus tumor and discusses the importance of the need to recognize the symptoms and clinical findings of both typical and atypical presentation of this abnormality in differentiation and differential treatment and risk management of benign and malignant soft-tissue masses.

Intraorbital and intracranial soft-tissue glomus tumor in an 8-year-old child

2008 ◽  
Vol 1 (5) ◽  
pp. 389-391 ◽  
Author(s):  
Todd C. Hankinson ◽  
Alfred T. Ogden ◽  
Peter Canoll ◽  
James H. Garvin ◽  
Michael Kazim ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Cranial Nerve ◽  
Cranial Nerve Palsy ◽  
Nerve Palsy ◽  
Glomus Tumor ◽  
Middle Cranial Fossa ◽  
Sixth Cranial Nerve ◽  
Glomus Tumors ◽  
Proton Beam Radiotherapy ◽  
Sixth Cranial Nerve Palsy

✓ Soft-tissue glomus tumors (or glomangiomas) are unrelated to neuroendocrine paragangliomas (glomus tympanicum, jugulare, and vagale). The authors present the first reported case of an orbital soft-tissue glomus tumor in a child. An 8-year-old girl developed rapidly progressive right-eye blindness, proptosis, and a sixth cranial nerve palsy. Magnetic resonance imaging demonstrated a homogeneously enhancing lesion extending from the right orbit through the superior orbital fissure to the cavernous sinus and middle cranial fossa. A biopsy specimen demonstrated the lesion to be a soft-tissue glomus tumor. Following angiography and embolization, a gross-total resection of the tumor was achieved. The patient was treated with adjuvant proton-beam radiotherapy. At 24 months follow-up her proptosis and sixth cranial nerve palsy had resolved and there was no evidence of tumor recurrence.

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