Glomus Tumor

2008 ◽  
Vol 132 (9) ◽  
pp. 1448-1452 ◽  
Author(s):  
Zoltan Gombos ◽  
Paul J. Zhang

Abstract Glomus tumor is a benign mesenchymal neoplasm comprising less than 2% of soft tissue tumors. It is composed of cells resembling modified smooth muscle cells of the normal glomus body. The glomus body, a thermoregulator, is a specialized form of arteriovenous anastomosis localized in dermal and precoccygeal soft tissue. Although glomus tumors are rare neoplasms, clinical misdiagnosis of many of these lesions as hemangiomas or venous malformations makes an accurate assessment of their actual prevalence difficult. A malignant counterpart of this lesion exists but is extremely rare.

2015 ◽  
Vol 2015 ◽  
pp. 1-3 ◽  
Author(s):  
Kemal Beksaç ◽  
Lutfi Dogan ◽  
Nazan Bozdogan ◽  
Gulay Dilek ◽  
Gokhan Giray Akgul ◽  
...  

Glomus tumors are benign neoplasms that arise from neuromyoarterial glomus bodies. They represent around 1–5% of all soft-tissue tumors. High temperature, sensitivity, and pain and localized tenderness are the classical triad of symptoms. Most glomus tumors represent in the subungual area of digits. Extradigital glomus tumors are a very rare entity. There are rare cases of these tumors reported to be in shoulder, elbow, knee, wrist, even stomach, colon, and larynx. We are reporting a case of a glomus tumor on thigh and discuss the histological and immunohistochemical features.


2020 ◽  
Vol 2 ◽  
pp. 82-86
Author(s):  
Vikas Batra ◽  
Nafisa Shakir Batta ◽  
Ankur Gupta

Glomangiomas (glomus tumors) are benign vascular tumors commonly located at the distal extremities, are usually subungual lesions, and account for 2% of all soft-tissue tumors. Patients with digital glomus tumors present with hypersensitivity to cold, paroxysmal severe pain, and point tenderness. These tumors are infrequent in the knee area, and when seen are superficial, usually have a diameter of less than 1 cm, which make their radiological diagnosis arduous. We report a noteworthy, unusual case of a large glomus tumor in the popliteal fossa showing biceps femoris infiltration, in a 51-year-old female patient who experienced severe intermittent posterior knee pain for the past 2 years. Magnetic resonance imaging revealed a large popliteal inhomogeneous soft-tissue lesion with irregular margins insinuating the posterolateral musculature mimicking soft-tissue sarcoma. Histopathology revealed a glomus tumor.


2021 ◽  
Vol 0 ◽  
pp. 1-4
Author(s):  
Debanjan Nandi ◽  
Kiran Madhavrao Zadte ◽  
Ipsita Dhal

Glomus tumors are benign neoplasms that arise from neuromyoarterial glomus bodies accounting for <2% of soft-tissue tumors. Glomus tumors represent around 1–5% of all soft-tissue tumors and 1–5% of all hand tumors. About 75% of these tumors occur in hand with 75–90% of these occurring in characteristic subungual location. Extradigital location of glomus tumor is very rare. We report an exceptional case of extradigital glomus tumor causing thigh pain, where there were a pair of lesions both in periosteum and intramuscular location. A 47-year-old male with complaints of pain over medial aspect of the left lower thigh for 2 years on ultrasound revealed well-defined solid hypoechoic lesions within the left vastus medialis muscle and cortical-based lesion abutting the periosteum of distal diaphysis of the left femur on medial aspect. These lesions were hypointense on T1W, hyperintense on T2W and showed early homogenous enhancement on MRI. Histopathology revealed glomus tumors, which commonly occur in digits. Glomus tumors located in both periosteal and intramuscular locations in thigh were in very uncommon. Non-specific presentation with pain in such cases remains a diagnostic dilemma. Role of multimodality imaging and histopathology correlation is important in such situation.


2017 ◽  
Vol 12 (2) ◽  
pp. 64-67
Author(s):  
Md Maiyeen Uddin ◽  
Swapan Kumar Biswas ◽  
Md Habibur Rahman ◽  
Narayan Chandra Karmakar ◽  
Md Masudur Rahman ◽  
...  

Glomus tumors are benign hamartoma of glomus body. It accounts 1-5% of all soft tissue tumors of hand. They can cause recurrent episodes of intense lancinating pain and disability. Patients often undergo undiagnosed or misdiagnosed for many years because the tumors are small. Twenty patients were operated during the period of 2010 to 2015. Most of the cases were selected on the basis of clinical diagnosis. The help of magnetic resonance imaging was taken in suspicious cases. The only treatment of glomus tumor is total surgical excision. In this study surgical excision were performed by direct trans-ungual approach. All patients showed dramatic relief of pain after surgical excision. Early diagnosis and surgical excision decreases patient's sufferings from severe pain and disability. Eagerness in early diagnosis and surgical excision can reduce long period of sufferings.Faridpur Med. Coll. J. Jul 2017;12(2): 64-67


2021 ◽  
Vol 49 (01) ◽  
pp. 046-055
Author(s):  
Victoria Hernández ◽  
Tania Lena ◽  
Eliana Camacho ◽  
Matías Craviotto

AbstractGlomus tumors are a mostly benign neoplasm that constitutes less than 4% of upper-limb soft-tissue tumors. Its unspecific clinical presentation, added to its low frequency, leads to a late diagnosis.The objective of the present study is to update the clinical-paraclinical approach and the surgical technique used in the treatment.We carried out a literature review from 2014 to 2019 on digital glomus tumor in the hand in adult patients using the PubMed search engine.In most of the publications analyzed, the diagnosis was clinical, with a delay of 1 to 10 years. Plain radiography is the most requested study; of the 16 articles reporting its indication, only half evidenced compatible changes. Magnetic resonance imaging (MRI) was requested in 15 articles, presenting normal results in 3 of them. The treatment of choice was surgical excision using a transungual approach. Only 4 articles report recurrence after excision.Although there is diversity in the approach to these tumors, we conclude that the diagnosis is clinical, and the treatment surgical, and there is no consensus regarding the paraclinical indication. The information available comes mainly from case reports, publications that contribute to the generation of evidence for the clinical practice in rare diseases such as this one.


2021 ◽  
pp. 11-12
Author(s):  
Mohit Naren Kondapalli ◽  
Kishore Babu EP ◽  
Affee Asma

Glomus tumour, also referred to as Barré–Masson syndrome is an enigmatic, rare, painful tumour that is that represents a proliferation of the normal capsular-neural glomus apparatus. These are rare hamartomas that arise from the traditional glomus apparatus, located in subcutaneous tissue These are benign soft tissue neoplasms presenting usually within the second to fourth decade of life, originating from the glomus body. It accounts for 1-5% of all upper limb soft tissue tumors . It's a component of the dermis layer of the [1] skin, involved in thermoregulation. It structurally consists of an arterio-venous shunt which is surrounded by a connective tissue capsule and is found in increased amounts in the ngers and toes.


2017 ◽  
Vol 107 (3) ◽  
pp. 257-260 ◽  
Author(s):  
Robert L.B. Sprinkle ◽  
Omar P. Sangueza ◽  
Gregory A. Schwartz

A glomus tumor is an uncommon, predominantly benign, neoplastic lesion that primarily involves a thermoregulatory microvascular apparatus, the glomus body. Although these lesions can occur anywhere in the body, the subungual tissue of the hand represents the most common presentation site. Glomus tumors are not often encountered in the foot. Symptoms traditionally include the classic triad of pain, pressure, and cold sensitivity. This case report describes a variant location for a glomus tumor in the subcuticular tissue adjacent to the medial middle phalanx of the second toe. The nonsubungual location for this presentation should prompt the inclusion of glomus tumor in a digital soft-tissue lesion differential diagnosis. The lesion was excised surgically and was subsequently diagnosed histopathologically as a glomus tumor.


2021 ◽  
Vol 156 (Supplement_1) ◽  
pp. S73-S73
Author(s):  
J Nwanze ◽  
J Shih ◽  
N Rolf ◽  
S K Halat

Abstract Introduction/Objective Glomus tumors are rare neoplasms arising from the glomus body which is a specialized arteriovenous anastomosis that has a role in temperature regulation of the skin. They account for less than 2% of soft tissue tumors and typically manifest as painful nodules in the extremities, most commonly in the subungual region of the fingers and dermis of the wrist, forearm, and foot. They rarely arise in visceral organs as they lack glomus bodies. There are rare case reports of benign glomus tumors arising in the kidney, and malignant renal glomus tumors are exceedingly rare. Methods/Case Report We present a case of a 32-year-old man who was found to have a right renal mass incidentally after being involved in a motor vehicle accident. Computed tomography of the abdomen revealed a 5.3 cm enhancing mass in the posterior aspect of the inferior pole of the right kidney. Histological examination revealed a solid neoplasm composed of a pleomorphic population of cells with densely eosinophilic to pale cytoplasm, centrally located round to oval nuclei with fine nuclear chromatin and relatively inconspicuous nucleoli. Prominent lymphovascular invasion and 1 mitotic figure per 10 high power fields were also present. Areas composed of necrosis, sclerosis, hemosiderin deposition and calcification were identified. Immunohistochemical stains revealed the neoplastic cells to be positive for CD34, vimentin, smooth muscle actin, caldesmon, with focal reticulin staining around the tumor cells. Cells were negative for desmin, high and low molecular weight cytokeratins, synaptophysin, chromogranin, PAX8, and GATA3. The morphology and immunoprofile of the mass are consistent with the diagnosis of glomus tumor. Results (if a Case Study enter NA) NA Conclusion Although very rare, the presence of prominent vascular invasion, increased mitotic activity as well as necrosis are consistent with malignant behavior and support the classification as a malignant glomus tumor.


2020 ◽  
Vol 8 ◽  
pp. 232470962093615
Author(s):  
Sara Naji Rad ◽  
Samira Najirad ◽  
Rana Rafiei

Glomus tumors are mesenchymal neoplasms derived from glomus bodies with rare presentations in the oral cavity. Glomus tumors present as a purple or pink vascular nodule or papule, sized <1 cm, and imitate vascular neoplasms such as hemangiopericytoma or hemangioma. Glomus tumors represent less than 2% of all benign soft tissue tumors. Only 27 cases of benign glomus tumors with oral cavity involvement have been reported to date. The most-reported oral tumors involved the lips (54.2%), followed by hard palate, gingiva, tongue, and buccal mucosa. The mean age of presentation of the labial glomus tumors is 48.7 years, with no gender predilection, in contrast to the subungual site, which occurs more in females. The etiology of the glomus tumors remains unknown. Subungual glomus tumors present as stabbing pain, cold intolerance, and tenderness of the fingertips, whereas labial glomus tumors mostly present as a painless, small, and slow-growing lesion. Treatment is surgical resection of the tumor. The recurrence rate of labial glomus tumors is unclear. In this article, we present the case of a 62-year-old man with a 2-month history of painless, soft lump on the mucosal surface of the lower left lip. Excisional resection of the tumor was performed in the clinic, and the histopathologic finding was consistent with solid glomus tumor. At 1 year follow-up there was no recurrence.


2020 ◽  
Vol 2 (1) ◽  
pp. 01-04
Author(s):  
Rolanda A. Willacy

Glomus bodies are neuromyoarterial apparatuses of the skin, implicated in body temperature control, and may undergo transformation with unregulated hyperplasia of their smooth muscle component. Glomus tumors most commonly occur in the subungual region of the fingers. These benign tumors are rare and constitute 1-5% of soft tissue tumors of the hand and may present as solitary or multiple masses. Solitary glomus tumors present with a classic triad of localized tenderness, severe pain, and cold sensitivity. We report a rare case of glomus tumor in the elbow and a review of the histopathological findings.


Sign in / Sign up

Export Citation Format

Share Document