The role of general medical examination of the population in the detection of glaucoma

2021 ◽  
pp. 41-43
Author(s):  
O.G. Ionova ◽  
◽  
V.M. Hokkanen ◽  
E.A. Derevtsova ◽  
◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Medical Records ◽  
Early Stage ◽  
Screening Method ◽  
Medical Examination ◽  
Second Stage ◽  
Field Of Vision ◽  
Primary Glaucoma ◽  
Pressure Changes

Purpose. The aim of this study was to examine effectiveness of the General medical examination of the population in identifying patients with glaucoma. Material and methods. An analysis of 17593 medical records of patients older 40 years old who underwent a screening method for measuring intraocular pressure was performed for period 2016-2018. When an increased intraocular pressure was detected, an in-depth examination was carried out at the second stage. Results. An increase in intraocular pressure was found in 3.7% of the surveyed (642 people). The second stage of clinical examination showed that 298 people (1.7%) had signs of primary glaucoma (high and borderline values of intraocular pressure, changes in the field of vision). Further in-depth examination in a specialized glaucoma center revealed that 186 people had glaucoma, with 84% cases at the first stage. Conclusion. General medical examination revealed glaucoma at an early stage of the disease 1.1% of the surveyed. Key words: general medical examination, screening method, glaucoma.

The role of general medical examination of the population in the detection of glaucoma

2021 ◽  
pp. 75-77
Author(s):  
O.G. Ionova ◽  
◽  
V.M. Hokkanen ◽  
E.A. Derevtsova ◽  
◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Medical Records ◽  
Early Stage ◽  
Screening Method ◽  
Medical Examination ◽  
Second Stage ◽  
Field Of Vision ◽  
Primary Glaucoma ◽  
Pressure Changes

Purpose. The aim of this study was to examine effectiveness of the General medical examination of the population in identifying patients with glaucoma. Material and methods. An analysis of 17593 medical records of patients older 40 years old who underwent a screening method for measuring intraocular pressure was performed for period 2016-2018. When an increased intraocular pressure was detected, an in-depth examination was carried out at the second stage. Results. An increase in intraocular pressure was found in 3.7% of the surveyed (642 people). The second stage of clinical examination showed that 298 people (1.7%) had signs of primary glaucoma (high and borderline values of intraocular pressure, changes in the field of vision). Further in-depth examination in a specialized glaucoma center revealed that 186 people had glaucoma, with 84% cases at the first stage. Thus, general medical examination revealed glaucoma at an early stage of the disease 1.1% of the surveyed. Key words: general medical examination, screening method, glaucoma.

Finite Element Modeling of the Connective Tissues of the Optic Nerve Head in Bilaterally Normal Monkeys

2009 ◽  
Author(s):  
Michael D. Roberts ◽  
Ian A. Sigal ◽  
Yi Liang ◽  
Claude F. Burgoyne ◽  
J. Crawford Downs
Keyword(s):  
Finite Element ◽  
Intraocular Pressure ◽  
Optic Nerve ◽  
Finite Element Modeling ◽  
Optic Neuropathy ◽  
Optic Nerve Head ◽  
Connective Tissues ◽  
Element Modeling ◽  
Field Of Vision

Glaucoma is a chronic and progressive optic neuropathy that gradually narrows the field of vision and can culminate in blindness. Despite extensive and prolonged research efforts, the mechanisms that initiate and fuel progression of the disease are not well understood. However, reduction of intraocular pressure (IOP) has been shown to be an effective therapy for slowing glaucomatous progression, although the specific role of IOP in the disease is not well understood.

An integrated screening method for evaluating the pulmonary toxicity of inhaled particulates: Role of microscopic techniques in assessing pulmonary macrophage clearance functions

1990 ◽  
Vol 48 (3) ◽  
pp. 826-827
Author(s):  
David B. Warheit ◽  
Lena Achinko ◽  
Mark A. Hartsky
Keyword(s):  
Bronchoalveolar Lavage ◽  
Pulmonary Toxicity ◽  
Screening Method ◽  
Pulmonary Response ◽  
Inhaled Particles ◽  
Cytochemical Analysis ◽  
Pulmonary Macrophages ◽  
Integrated Screening

There is a great need for the development of a rapid and reliable bioassay to evaluate the pulmonary toxicity of inhaled particles. A number of methods have been proposed, including lung clearance studies, bronchoalveolar lavage analysis, and in vitro cytotoxicity tests. These methods are often limited in scope inasmuch as they measure only one dimension of the pulmonary response to inhaled, instilled or incubated dusts. Accordingly, a comprehensive approach to lung toxicity studies has been developed.To validate the method, rats were exposed for 6 hours or 3 days to various concentrations of either aerosolized alpha quartz silica (Si) or carbonyl iron (CI) particles. Cells and fluids from groups of sham and dust-exposed animals were recovered by bronchoalveolar lavage (BAL). Alkaline phosphatase, LDH and protein values were measured in BAL fluids at several time points postexposure. Cells were counted and evaluated for viability, as well as differential and cytochemical analysis. In addition, pulmonary macrophages (PM) were cultured and studied for morphology, chemotaxis, and phagocytosis by scanning electron microscopy.

The Diagnosis of Lupus Anticoagulants by the Activated Partial Thromboplastin Time - The Central Role of Phosphatidyl Serine

1984 ◽  
Vol 52 (02) ◽  
pp. 172-175 ◽  
Author(s):  
P R Kelsey ◽  
K J Stevenson ◽  
L Poller
Keyword(s):  
Screening Method ◽  
Coagulation Factors ◽  
Phosphatidyl Serine ◽  
Test System ◽  
Specific Factor ◽  
Marginal Effect ◽  
Constant Composition ◽  
Lupus Anticoagulants ◽  
Different Types

SummaryLiposomes of pure phospholipids were used in a modified APTT test system and the role of phosphatidyl serine (PS) in determining the sensitivity of the test system to the presence of lupus anticoagulants was assessed. Six consecutive patients with lupus anticoagulants and seven haemophiliacs with anticoagulants directed at specific coagulation factors, were studied. Increasing the concentration of phospholipid in the test system markedly reduced the sensitivity to lupus anticoagulants but had marginal effect on the specific factor inhibitors. The same effect was achieved when the content of PS alone was increased in a vehicle liposome of constant composition.The results suggest that the lupus anticoagulants can best be detected by a screening method using an APTT test with a reagent of low PS content. The use of a reagent rich in PS will largely abolish the lupus anticoagulant’s effect on the APTT. An approach using the two different types of reagent may facilitate differentiation of lupus inhibitors from other types of anticoagulant.

The role of compulsory periodical medical examination in employee’s dental health maintenance

2020 ◽  
pp. 678-678
Author(s):  
E. Y. Leontyeva ◽  
T. Y. Bykovskaya
Keyword(s):  
Oral Cavity ◽  
Dental Health ◽  
Medical Examination ◽  
Health Maintenance

The analysis of the appealability for the rehabilitation of the oral cavity of staff subject to mandatory periodic examinations at the dentist. The growth of indicators characterizing the dental activity of employees was noted. Subject to the principle of continuity, annual mandatory periodic examinations can be one of the factors in maintaining the dental health of employees.

Role of Carboplatin in the Treatment of Triple Negative Early- Stage Breast Cancer

2015 ◽  
Vol 10 (2) ◽  
pp. 101-110 ◽  
Author(s):  
Matias E. Valsecchi ◽  
Gerrit Kimmey ◽  
Arvinder Bir ◽  
Damian Silbermins
Keyword(s):  
Breast Cancer ◽  
Triple Negative ◽  
Early Stage ◽  
Early Stage Breast Cancer
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