scholarly journals New diagnostic biomarker in acute diarrhea due to bacterial infection in children

2017 ◽  
Vol 4 (2) ◽  
pp. 75-80 ◽  
Author(s):  
Hassan M. Al-Asy ◽  
Rasha M. Gamal ◽  
Ahmed M. Abd Albaset ◽  
Mohammed G. Elsanosy ◽  
Maali M. Mabrouk
Keyword(s):  
Bacterial Infection ◽  
Acute Diarrhea ◽  
Diagnostic Biomarker

Procalcitonin Testingreduce Unnecessary Antibiotic Use in Bacterial Infection

2019 ◽  
Vol 2 (1) ◽  
pp. 1-3
Author(s):  
Attabak Toofani Milani ◽  
Mahshid Mohammadian ◽  
Sadegh Rostaminasab ◽  
Roghayeh Paribananaem ◽  
Zohre Ahmadi ◽  
...  
Keyword(s):  
Antibiotic Therapy ◽  
Bacterial Infection ◽  
Diagnostic Test ◽  
Bacterial Infections ◽  
Intervention Studies ◽  
Antibiotic Use ◽  
Clinical Suspicion ◽  
Diagnostic Biomarker ◽  
Clinical Routine ◽  
Initial Rise

Conventional diagnostic test have limitations to deferential diagnosis in clinical suspicion ofbacterial infection cases, that in some cases lead to inappropriate antibiotic therapy and increases antibiotic resistance. A new diagnostic insight is procalcitonin (PCT) test to improve diagnosis of bacterial infections and to guide antibiotic therapy. Serum PCT levels are of useful test as a biomarker in patients with bacterial infections for several reasons. Initial rise of PCT levels due to bacterial infection, subsequent sequential PCT levels can be used to assess the effectiveness and duration of antibiotic therapy. Based on clinical researches results, in bacterial infections, promising good results obtained when use of PCT used as differential diagnostic test. But further intervention studies are needed before use of PCT in clinical routine tests. The goal of this review is to study the PCT reliability as infections diagnostic biomarker.

scholarly journals Interleukin-27 is a novel candidate diagnostic biomarker for bacterial infection in critically ill children

Critical Care ◽  
2012 ◽  
Vol 16 (5) ◽  
pp. R213 ◽  
Author(s):  
Hector R Wong ◽  
Natalie Z Cvijanovich ◽  
Mark Hall ◽  
Geoffrey L Allen ◽  
Neal J Thomas ◽  
...  
Keyword(s):  
Bacterial Infection ◽  
Critically Ill ◽  
Critically Ill Children ◽  
Diagnostic Biomarker ◽  
Interleukin 27

scholarly journals Procalcitonin Testingreduce Unnecessary Antibiotic Use in Bacterial Infection

2019 ◽  
Vol 2 (1) ◽  
pp. 1-3
Author(s):  
Attabak Toofani Milani ◽  
Mahshid Mohammadian ◽  
Sadegh Rostaminasab ◽  
Roghayeh Paribananaem ◽  
Zohre Ahmadi ◽  
...  
Keyword(s):  
Antibiotic Therapy ◽  
Bacterial Infection ◽  
Diagnostic Test ◽  
Bacterial Infections ◽  
Intervention Studies ◽  
Antibiotic Use ◽  
Clinical Suspicion ◽  
Diagnostic Biomarker ◽  
Clinical Routine ◽  
Initial Rise

Conventional diagnostic test have limitations to deferential diagnosis in clinical suspicion ofbacterial infection cases, that in some cases lead to inappropriate antibiotic therapy and increases antibiotic resistance. A new diagnostic insight is procalcitonin (PCT) test to improve diagnosis of bacterial infections and to guide antibiotic therapy. Serum PCT levels are of useful test as a biomarker in patients with bacterial infections for several reasons. Initial rise of PCT levels due to bacterial infection, subsequent sequential PCT levels can be used to assess the effectiveness and duration of antibiotic therapy. Based on clinical researches results, in bacterial infections, promising good results obtained when use of PCT used as differential diagnostic test. But further intervention studies are needed before use of PCT in clinical routine tests. The goal of this review is to study the PCT reliability as infections diagnostic biomarker.

scholarly journals Macronutrient malabsorption in acute diarrhea: Prevalence and affecting factors

2016 ◽  
Vol 45 (5) ◽  
pp. 207
Author(s):  
Lilis D. Hendrawati ◽  
Agus Firmansyah ◽  
Darlan Darwis
Keyword(s):  
Bacterial Infection ◽  
Acute Diarrhea ◽  
Age Groups ◽  
Cross Sectional Study ◽  
Affecting Factors ◽  
Cross Sectional ◽  
Lactose Malabsorption ◽  
Diarrhea Prevalence ◽  
Fat Malabsorption ◽  
Age Range

Introduction Diarrhea remains a major problem for communityhealth in Indonesia. More than 25% of children with severe diar-rhea suffer from malabsorption syndrome.Objectives This study aimed to determine the age range of chil-dren with acute diarrhea, the prevalence of macronutrient malab-sorption, and the relationship between age and bacterial infec-tion in macronutrient malabsorption.Methods This was a cross-sectional study, subjects were chil-dren aged 0-59 months with acute diarrhea whose stools wereobtained and examined in the laboratory of GastrohepatologyDivision, Department of Child Health, Cipto Mangunkusumo Hospi-tal, Jakarta from January 2002 to December 2003.Results Children with acute diarrhea were mostly in the agerange of 0-11 months (61%). The prevalence of lactose malab-sorption was 11%, carbohydrate malabsorption was 19%, andfat malabsorption was 51%. Moreover, the age group of 0-11months had a 1.5 times greater possibility of lactose and fatmalabsorption compared to that of 12-59 months. The 12-59 monthsage group had a greater possibility of suffering carbohydratemaldigestion (70%). The group of children who did not sufferfrom bacterial infection had a higher prevalence of lactose mal-absorption (54%), carbohydrate maldigestion (65%), and fatmalabsorption (58%).Conclusions Acute diarrhea occurred more frequently in theage of 0-11 months. There was a significant correlation betweenthe age groups of 0-11 months and 12-59 months in experiencingmacronutrient malabsorption. Lactose malabsorption, carbohy-drate maldigestion, and fat malabsorption were encountered morefrequently in the group that did not have bacterial infection

scholarly journals Interleukin-27 as a candidate diagnostic biomarker for bacterial infection in immunocompromised pediatric patients

PLoS ONE ◽  
2018 ◽  
Vol 13 (11) ◽  
pp. e0207620 ◽  
Author(s):  
Lauren Jacobs ◽  
Zachary Berrens ◽  
Erin K. Stenson ◽  
Matthew Zackoff ◽  
Lara Danziger-Isakov ◽  
...  
Keyword(s):  
Bacterial Infection ◽  
Pediatric Patients ◽  
Diagnostic Biomarker ◽  
Interleukin 27

scholarly journals Serum Procalcitonin as a Diagnostic Biomarker for Bacterial Infection in Febrile Children

2017 ◽  
Vol 06 (01) ◽  
Author(s):  
Osama Y Safdar ◽  
Abdulmalik A Alghamdi ◽  
Duaa F Jastaniyyah ◽  
Daniya O Abdouh ◽  
Feras L AlKindi ◽  
...  
Keyword(s):  
Bacterial Infection ◽  
Diagnostic Biomarker

scholarly journals A study for Bacterial Infection in Acute Diarrhea Patients

2014 ◽  
Vol 11 (2) ◽  
pp. 757-760
Author(s):  
Baghdad Science Journal
Keyword(s):  
Bacterial Infection ◽  
Acute Diarrhea ◽  
Biochemical Test ◽  
The Other ◽  
Gram Negative Bacteria ◽  
Gram Negative ◽  
E Coli ◽  
Different Ages ◽  
Public Laboratory ◽  
First Time

500 samples of diarrhea stool were collected from different ages(less than 1year –upto30years) and for both genders from some patients in (Alwiya hospital for children, Al-kendi, central health public laboratory and some gavernarated labs) period(1/11/2009—1/10/2010). Kinds of bacteria and parasites agents were isolated and identified from patients with diarrhea. Nine species of gram negative bacteria from enterobacteriaceae were isolated, E. coli isolated are the higher ratio 4.8% of all, then Salmonella typhi4.6% while the lowest ratios is Citrobacterfreundii 0.4%, while the other identified species were be among the previous rotios. also Plesomonasshigelloides was isolated which concedride one of the bacterial local studies.many methods were depend on in order to identifiy; growth on media like (Enrichment ,differentials and differetials) media. Biochemical test represents with API20E, also. Some confirmed tests represent with a modern and important identical tools was used for first time to identify the entericbacteria, by (Rapid ID 32) usually used with mini API system where the results record automatically.

scholarly journals Clinical application of presepsin as diagnostic biomarker of infection: overview and updates

2019 ◽  
Vol 58 (1) ◽  
pp. 11-17 ◽  
Author(s):  
Emanuela Galliera ◽  
Luca Massaccesi ◽  
Elena de Vecchi ◽  
Giuseppe Banfi ◽  
Massimiliano M. Corsi Romanelli
Keyword(s):  
Intensive Care ◽  
Bacterial Infection ◽  
Pulmonary Infection ◽  
Immune Cell ◽  
Fungal Infections ◽  
Neonatal Infection ◽  
Diagnostic Biomarker ◽  
Infective Disease ◽  
Immune Cell Response ◽  
And Control

Abstract The appropriate identification of bacterial infection is the basis for effective treatment and control of infective disease. Among this context, an emerging biomarker of infection is presepsin (PSP), recently described as early marker of different infections. PSP secretion has been shown to be associated with monocyte phagocytosis and plasmatic levels of PSP increase in response to bacterial infection and decrease after antibiotic treatment, therefore it can be considered a marker of activation of immune cell response towards an invading pathogen. Different methods have been developed to measure PSP and this review will briefly describe the different clinical fields of application of PSP, ranging from intensive care to neonatal infection, to orthopedic and pulmonary infection as well as fungal infections and cardiovascular infections.

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