HEALTHCARE-ASSOCIATED FACTORS CORRELATED WITH NEONATAL COAGULASE-NEGATIVE STAPHYLOCOCCUS SPP. INFECTION

2017 ◽  
Author(s):  
Christina Kortsalioudaki
Keyword(s):  
Associated Factors ◽  
Coagulase Negative Staphylococcus ◽  
Healthcare Associated ◽  
Staphylococcus Spp

scholarly journals Some coagulase negative Staphylococcus spp. isolated from buffalo can be misidentified as Staphylococcus aureus by phenotypic and Sa442 PCR methods

2018 ◽  
Vol 11 (1) ◽  
Author(s):  
Camila C. de Almeida ◽  
Lucas J. L. Pizauro ◽  
Glenn A. Soltes ◽  
Durda Slavic ◽  
Fernando A. de Ávila ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Coagulase Negative Staphylococcus ◽  
Staphylococcus Spp

#38: Bacteremia Analysis of Three Hospitals in Hispaniola Island

2021 ◽  
Vol 10 (Supplement_2) ◽  
pp. S19-S19
Author(s):  
Johanny Contreras ◽  
Karina Rivera ◽  
María Castillo ◽  
Genara Santana ◽  
María Dolores Gil ◽  
...  
Keyword(s):  
Lymphoblastic Leukemia ◽  
Mucosal Barrier ◽  
Infection Prevention And Control ◽  
Coagulase Negative Staphylococcus ◽  
Case Definitions ◽  
Culture Methods ◽  
Isolation And Identification ◽  
Infection Surveillance ◽  
Prophylactic Measures ◽  
Healthcare Associated

Abstract Background In October 2018, the Hispaniola Project was initiated to build local expertise in infection care and prevention at three pediatric oncology units (POUs) in Haiti and the Dominican Republic. Surveillance of healthcare-associated infections (HAI) was a central aim. Severe and prolonged neutropenia is a frequent risk factor for infections in oncology patients. Among HAIs, bacteremia is one of the most serious; bacteremia requires timely isolation and identification of the offending microorganism and the antimicrobial susceptibility. These diagnostic interventions allow informed therapeutic and prophylactic measures. Here, we report our experience in bacteremia in these 3 POUs. Methods We conducted prospective infection surveillance of all patients admitted to three POUs in Hispaniola Island. Blood culture methods followed standard national procedures. We used the 2018 US Centers for Disease Control National Healthcare Safety Network case definitions for primary laboratory-confirmed bloodstream infections (LCBI), and we categorized infections as healthcare-associated or present on admission (POA). We reviewed data collected from January 2019 to December 2020 and used descriptive statistics to report our results. Results Our review identified 66 LCBIs with an overall rate of 3.52 infections per 1000 patient-days. Of these, 40 (61%) were healthcare-associated, and 26 were POA. The majority (41, 62%) of patients were undergoing chemotherapy at the time of the infection, with induction being the most common phase (23). The most common oncologic diagnosis was acute lymphoblastic leukemia (43, 65%), followed by solid tumor (12, 18%). Fifty-three (80%) of the infections met the LCBI-1 criteria, with the other 13 categorized as LBCI-2. Of the 53 LCBI-1, 7 (13%) were considered related to mucosal barrier injury (MBI-LCBI 1 definition). The most commonly identified organisms were Klebsiella spp. (13, 19%) and coagulase-negative Staphylococcus (13, 19%). Antibiotic resistance was observed in many of the identified pathogens, with nearly half (25, 44%) of the 57 bacterial isolates having any resistance and a quarter (14, 25%) with resistance to multiple classes, including cephalosporins, fluoroquinolones, and aminoglycosides. Eleven (17%) patients were admitted to the Intensive Care Unit as a result of the LCBI. Thirteen deaths were recorded among the patients with LCBIs, with 6 (46%) associated with the HAI and 7 (54%) related to disease progression. Conclusions Our findings demonstrate that resistant pathogens were frequent among the LCBI isolates. Our preliminary results are guiding clinical management to be vigilant in our care of patients at high risk for bacteremia and poor clinical response by initiating more effective antimicrobials sooner. Importantly, reviewing reasons for antimicrobial resistance and implementing best antimicrobial use practices will protect our fragile antibiotic arsenal. Infection surveillance programs, such as ours, and other initiatives which promote infection prevention and control in POU will increase the quality of care for these vulnerable patients.

scholarly journals Characterization of mecC gene-carrying coagulase-negative Staphylococcus spp. isolated from various animals

2019 ◽  
Vol 230 ◽  
pp. 138-144 ◽  
Author(s):  
Igor Loncaric ◽  
Anna Kübber-Heiss ◽  
Annika Posautz ◽  
Werner Ruppitsch ◽  
Sarah Lepuschitz ◽  
...  
Keyword(s):  
Coagulase Negative Staphylococcus ◽  
Staphylococcus Spp

scholarly journals Effects of Dietary Vibroactivated Clinoptilolite Supplementation on the Intramammary Microbiological Findings in Dairy Cows

Animals ◽  
2020 ◽  
Vol 10 (2) ◽  
pp. 202 ◽  
Author(s):  
Dražen Đuričić ◽  
Tomislav Sukalić ◽  
Franjo Marković ◽  
Predrag Kočila ◽  
Ivona Žura Žaja ◽  
...  
Keyword(s):  
Dairy Cows ◽  
Treated Group ◽  
Control Group ◽  
Coagulase Negative Staphylococcus ◽  
Intramammary Infection ◽  
Streptococcus Uberis ◽  
Causative Agents ◽  
Amoxicillin Clavulanic Acid ◽  
Staphylococcus Spp ◽  
Arcanobacterium Pyogenes

The aim of this study was to determine the effects of dietary vibroactivated clinoptilolite supplementation on the intramammary microbiological findings in dairy cows, causative agents of potential intramammary infection, and their sensitivity to antibiotics. Cows (n = 78) were randomly divided into two groups: CPL-treated group that received clinoptilolite (CPL) in-feed (n = 38), i.e., 50 g natural powdered zeolite CPL, twice daily from the seventh month of pregnancy to 75 days after calving, and the control group (CON) of untreated cows (n = 40). Milk samples were taken from each cow on days 7, 25, 45, and 75 postpartum. The following causative pathogens were isolated in 86 udder quarters: Staphylococcus aureus in 5.81% of positive samples, Staphylococcus spp. 9.32%, coagulase-negative Staphylococcus (CNS) 22.09%, Streptococcus uberis 13.95%, Streptococcus agalactiae 1.16%, Streptococcus sp. 3.49%, Escherichia coli 8.13%, Enterococcus spp. 6.98%, Corynebacterium spp. 11.63%, Pasteurella sp. 10.47%, Serratia spp. 2.33%, and Arcanobacterium pyogenes, Citrobacter sp., Prototheca sp., and yeasts each in 1.16% of samples. Additionally, 3.87% of environmental microflora samples (n = 47) and 89.06% of udder samples (n = 1083) were bacteriologically negative. The most effective antibiotics were cefoperazone and amoxicillin-clavulanic acid, while cloxacillin and tetracycline were the least effective antibiotics in both groups. In the clinoptilolite supplemented (CPL) group (n = 38) of 14 cows, nine causative agents of mastitis were isolated in 27 quarters, while in the control (CON) group (n = 40) of 24 cows, 13 causative agents of mastitis were isolated in 59 quarters. Cows from the CON group had a 1.96 times higher risk of intramammary infection than cows from the CPL group during the observation period (odds ratio = 1.96, p = 0.0031; 95% CI = 1.2570–3.0770).

Multidrug resistant coagulase-negative Staphylococcus spp. isolated from cases of chronic rhinosinusitis in humans. Study from Poland

2021 ◽  
Keyword(s):  
Chronic Rhinosinusitis ◽  
Pathogenic Bacteria ◽  
Medical Center ◽  
Multidrug Resistant ◽  
Coagulase Negative Staphylococcus ◽  
Coagulase Negative Staphylococci ◽  
Methicillin Resistant ◽  
Resistant Strains ◽  
Ethmoid Sinuses ◽  
Staphylococcus Spp

Abstract For many years, coagulase-negative staphylococci (CoNS) have been considered non-pathogenic bacteria. However, recently, CoNS are becoming more common bacteriological factors isolated from cases of chronic rhinosinusitis in humans. Moreover, most of them represent the multidrug-resistant or/and methicillin-resistant profile, which significantly increases the therapeutic difficulties. The aim of the study was to characterize profile of resistant coagulase-negative staphylococci isolated from cases of chronic rhinosinusitis in patients treated in a Medical Center in Warsaw in 2015–2016. The study material was derived from patients with diagnosed chronic rhinosinusitis treated at the MML Medical Center in Warsaw. The material was obtained intraoperatively from maxillary, frontal, and ethmoid sinuses. In total, 1,044 strains were isolated from the studied material. Coagulase-negative staphylococci were predominant, with the largest share of Staphylococcus epidermidis. Isolated CoNS were mainly resistant to macrolide, lincosamide, and tetracycline. Among the S. epidermidis strains, we also showed 35.6% of MDR and 34.7% of methicillin-resistant strains. The same values for other non-epidermidis species were 31.5% and 18.5%, respectively and the percentage of strains with MAR >0.2 was greater in S. epidermidis (32.6%) than S. non-epidermidis (23.9%). Although the percentage of strains resistant to tigecycline, glycopeptides, rifampicin and oxazolidinones was very small (2.3%, 1.9%, 1.4% and 0.7% respectively), single strains were reported in both groups. The study has shown a high proportion of MDR and methicillin-resistant CoNS strains, which indicates a large share of drug-resistant microorganisms in the process of persistence of chronic rhinosinusitis; therefore, isolation of this group of microorganisms from clinical cases using aseptic techniques should not be neglected.

Left Pansinusitis and Periorbital and Intracranial Abscesses Due to Actinomyces Species

1988 ◽  
Vol 2 (3) ◽  
pp. 117-120
Author(s):  
Donald R. Paugh ◽  
Charles F. Koopmann
Keyword(s):  
Case Report ◽  
Paranasal Sinus ◽  
Frontal Sinus ◽  
Coagulase Negative Staphylococcus ◽  
Intracranial Abscess ◽  
Paranasal Sinusitis ◽  
First Case ◽  
Actinomyces Species ◽  
Spread Of Infection ◽  
Staphylococcus Spp

Paranasal sinusitis may occasionally be complicated by intraorbital or intracranial spread of infection. In this presentation, the authors report the case of a 17-year-old male with left pansinusitis complicated by periorbital and intracranial abscess secondary to an infection associated with Actinomyces spp. and coagulase-negative Staphylococcus spp. This appears to be the first case report of Actinomyces involvement in the orbit or frontal sinus. The potential morbidity and/or mortality associated with locally invasive paranasal sinus abscess is reviewed. The combined medical and surgical management of this problem is presented.

scholarly journals Toxin Production and Resistance of Staphylococcus Species Isolated from Fermented Artisanal Dairy Products in Benin

2020 ◽  
Vol 2020 ◽  
pp. 1-12
Author(s):  
Majoie Géroxie Tohoyessou ◽  
Wassiyath Mousse ◽  
Haziz Sina ◽  
Fernique Kona ◽  
Tania Azanghadji ◽  
...  
Keyword(s):  
Dairy Products ◽  
Food Poisoning ◽  
Toxin Production ◽  
Fermented Milk ◽  
Diffusion Method ◽  
Coagulase Negative Staphylococcus ◽  
Production And Distribution ◽  
Susceptibility Profiles ◽  
Staphylococcus Spp ◽  
Fermented Dairy

Staphylococcus species are considered as one of the major pathogens causing outbreaks of food poisoning. The aim of this work was to assess the toxinogenic and antibiotic susceptibility profiles of the strains of Staphylococcus spp isolated from three types of fermented dairy products (yoghourt, millet dêguê, and couscous dêguê). The isolation of the Staphylococcus strains was performed on selective media, and their identification was done using biochemical and molecular methods. The susceptibility at 15 antibiotics tested was assessed using the disc diffusion method. The immunodiffusion method was used to evaluate the toxin (luk-E/D, luk-S/F, ETA, and ETB) production. Biofilm formation was qualitatively researched on microplates. Less than half (42.77%) of the collected samples were contaminated with Staphylococcus spp. The yoghourt and millet dêguê samples collected in the afternoon were more contaminated than those collected in the morning. The S. aureus, S. capitis, and S. xylosus strains, respectively, were the most present. S. aureus was the only coagulase-positive species identified in our samples. The highest resistance to antibiotics was observed with penicillin (100%) irrespective of the nature of the sample. S. aureus strains were highly (71.4%) resistant to methicillin. The S. aureus strains were the most biofilm-forming (27.6%), followed by S. capitis strains. Panton and Valentine’s leukocidin (luk-S/F) was produced by only S. aureus strains at a rate of 8.33%. Only coagulase-negative Staphylococcus (CNS) produced Luk-E/D. The high rates of Staphylococci contamination indicate bad hygiene quality during the production and distribution of dairy products. It is, therefore, necessary to improve the quality of fermented milk products.

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