scholarly journals Enteropathy with impaired membrane digestion and the prospects for cytoprotective therapy

2021 ◽  
Vol 93 (2) ◽  
pp. 129-137
Author(s):  
A. I. Parfenov ◽  
O. V. Akhmadullina ◽  
N. I. Belostotsky ◽  
E. A. Sabelnikova ◽  
A. A. Novikov ◽  
...  
Keyword(s):  
Small Intestine ◽  
Mucous Membrane ◽  
Clinical Manifestation ◽  
Clinical Picture ◽  
Food Products ◽  
The Poor ◽  
Intestinal Infections ◽  
Poor Tolerance ◽  
Carbohydrate Intolerance ◽  
Main Clinical Manifestation

The article describes enteropathy with impaired membrane digestion (EIMD) as a new nosological form. The main clinical manifestation of EIMD is the poor tolerance of food products, in particular carbohydrates and a decrease in the activity of membrane enzymes, in particular, carbohydrates, in the mucous membrane of the small intestine. The cause of the disease can be acute intestinal infections, viruses, drugs and other agents that damage the small intestine. The pathophysiology, clinical picture and diagnosis of EIMD are described. The basis of therapy is rebamipide, which has the ability to reduce the symptoms of carbohydrate intolerance and increase the activity of disaccharidases.

DERMATOMYOSITIS: A CLINICAL CASE

2020 ◽  
Vol 6 (2) ◽  
pp. 13-16
Author(s):  
B. Barieva
Keyword(s):  
Autoimmune Diseases ◽  
Disease Progression ◽  
Muscle Weakness ◽  
Clinical Manifestation ◽  
Clinical Picture ◽  
Clinical Case ◽  
Idiopathic Inflammatory Myopathies ◽  
Striated Muscles ◽  
Inflammatory Myopathies ◽  
Main Clinical Manifestation

Dermatomyositis (DM) refers to idiopathic inflammatory myopathies (IIM). IIM -a group of chronic autoimmune diseases, the main clinical manifestation of which is muscle weakness, which is associated with inflammation of the striated muscles. The article presents a clinical case of dermatomyositis in a 45-year-old man, the trigger of which was insolation. Due to the polymorphism of the DM clinical picture, the patient was initially hospitalized in a skin and venereal dispensary, and from there transferred to the rheumatology Department. Timely diagnosis and specialized treatment led to stabilization of the patient and prevention of disease progression up to complete immobilization of the patient.

The formation of an artificial vagina by Baldwin's method

1930 ◽  
Vol 26 (2) ◽  
pp. 218-218
Author(s):  
I. F. Kharitonov
Keyword(s):  
Small Intestine ◽  
Mucous Membrane ◽  
Satisfactory Result ◽  
Congenital Absence ◽  
Near Future ◽  
Artificial Vagina

Session 4 / XII 1929 Dr. I. F. Kharitonov (speaker Dr. A. N. Syzganov). The formation of an artificial vagina by Baldwin's method with a completely satisfactory result for the near future was produced by the operator in one case of congenital absence of this organ; the method is not safe, fraught with complications; in the reported case, the mucous membrane of the newly formed vagina continues to secrete juice from the small intestine, which strongly irritates the surrounding tissues.

scholarly journals Intestinal epithelial dysplasia

2020 ◽  
pp. 91-94
Author(s):  
T. E. Taranushenko ◽  
E. M. Vasilyeva ◽  
E. V. Antsiferova ◽  
L. N. Karpova ◽  
Y. S. Shamova
Keyword(s):  
Small Intestine ◽  
Rare Disease ◽  
Histological Examination ◽  
Mucous Membrane ◽  
Clinical Case ◽  
Clinical Presentation ◽  
Epithelial Dysplasia ◽  
Intestinal Epithelial ◽  
Electronic Microscopy

The article presents a clinical case of intestinal epithelial dysplasia (tufting enteropathy), a rare disease which relates to congenital diarrheas, has a particular clinical presentation and is life-threating. The diagnosis was confirmed by histological examination and electronic microscopy of mucous membrane of small intestine. Additional evidence is substantiated for the existence of prenatal markers of intestinal epithelial dysplasia represented as polyhydramnios and intrauterine dilatation of fetal intestinal loops. These symptoms are considered to be a clinical hallmark of sodium and chloride diarrheas and are described in single cases in enteropathy called a microvillus inclusion disease.

Determination of the fat content in the pancreas and mucous membrane (mucosa) of the small intestine of pigs

1979 ◽  
Vol 13 (5) ◽  
pp. 546-548
Author(s):  
V. P. Pakhomov ◽  
N. N. Evgrafova ◽  
V. T. Sapleva
Keyword(s):  
Small Intestine ◽  
Mucous Membrane ◽  
Fat Content

scholarly journals Prosthodontic Management of Xerostomic Patient: A Technical Modification

2016 ◽  
Vol 2016 ◽  
pp. 1-6 ◽  
Author(s):  
Haraswarupa Gurkar ◽  
Omprakash Yadahally Venkatesh ◽  
Jagadeesh Mandya Somashekar ◽  
Muthuraj Hariharapura Lakshme Gowda ◽  
Madhavi Dwivedi ◽  
...  
Keyword(s):  
Psychological Health ◽  
Health Problems ◽  
Complete Denture ◽  
New Technique ◽  
Dental Prostheses ◽  
The Poor ◽  
Removable Dental Prostheses ◽  
Poor Tolerance ◽  
Common Problems ◽  
A New Technique

Xerostomia is often a contributing factor in both minor and serious health problems. It can affect nutrition and dental as well as psychological health. Common problems faced by such patients are glossitis, mucositis, angular cheilitis, dysgeusia, and difficulty in chewing and swallowing. One of the major problems associated with xerostomic patients is the poor tolerance and retention of removable dental prostheses because of thin dry atrophic mucosa and lack of a saliva film. This paper describes a new technique of incorporating a salivary reservoir in the maxillary complete denture. The salivary reservoir fabricated by this technique provided good lubrication of the oral tissues and was easily cleansed by the wearer and was fabricated from routine denture materials.

scholarly journals Differential diagnosis in hematochezia

2020 ◽  
pp. 87-93
Author(s):  
D. I. Trukhan ◽  
L. V. Tarasova ◽  
E. I. Busalaeva ◽  
O. L. Ariamkina
Keyword(s):  
Differential Diagnosis ◽  
Gastrointestinal Tract ◽  
Mucous Membrane ◽  
Clinical Picture ◽  
Bowel Movement ◽  
Differential Diagnostics

The appearance of hematohecia (blood in the bowel movement) is considered one of the most disturbing and serious symptoms of diseases of the gastrointestinal tract (GIT), signaling a violation of the integrity of the vessels of the intestine and mucous membrane. In the presented lecture the main diseases and conditions are considered, in the clinical picture of which the appearance of blood in the stool is noted, which must be considered in the course of differential diagnostics

scholarly journals The case of histiocytosis X (Hand - Schüller – Christian disease) with thyroid gland lesion

1996 ◽  
Vol 42 (3) ◽  
pp. 26-29
Author(s):  
M. E. Bronstein ◽  
G. A. Melnichenko ◽  
A. I. Bukhman ◽  
T. A. Starostina ◽  
O. L. Ivanov ◽  
...  
Keyword(s):  
Thyroid Gland ◽  
Rare Disease ◽  
Clinical Manifestation ◽  
Clinical Picture ◽  
Langerhans Cells ◽  
Morphological Changes ◽  
Eosinophilic Granuloma ◽  
Biological Significance ◽  
Histiocytosis X ◽  
Mutual Transition

Histiocytosis X, which is a rare disease, combines 3 related but different in clinical manifestation, course and prognosis of the syndrome: eosinophilic granuloma (Taratynovs disease), Hand Schller Christian disease (syndrome) and Letterer Siw disease (syndrome). The clinical picture of Hend Schller Christian disease was first described by Hand in 1893, then by Schller in 1915 and Christian in 1920. The term histiocytosis X was first proposed in 1953 by Liechtenstein, who combined all 3 of the aforementioned diseases under this name. on the basis of the similarity of the clinical picture, the possibility of a mutual transition from one state to another and typical morphological manifestations consisting in the proliferation of histiocytes and the accumulation of various lipids in their cytoplasm. In 1965, this concept was confirmed in all three diseases, there are no special pentalaminar markers in the cytoplasm of histiocytes that are detected in Langerhans cells (hence the name of these inclusions - "Langerhans cell granules"), the origin and biological significance of which remains unclear. Histiocytes have no signs of atypia, although they infiltrate many organs and tissues retain their normal properties. Histiocytic proliferation can develop in various organs and tissues, causing them to corresponding functional and morphological changes.

scholarly journals MORPHOLOGICAL CHANGES IN THE SMALL INTESTINE OF RATS WITH ACUTE GENERALIZED PERITONITIS

2019 ◽  
pp. 110-113
Author(s):  
I. Ya. Dzyubanovsky ◽  
B. M. Vervega ◽  
S. R. Pіdruchna ◽  
N. A. Melnyk
Keyword(s):  
Endothelial Cells ◽  
Small Intestine ◽  
Mucous Membrane ◽  
Morphological Changes ◽  
Histological Study ◽  
Abdominal Cavity ◽  
Inflammatory Infiltration ◽  
Generalized Peritonitis ◽  
White Rats ◽  
Fecal Suspension

The main cause of mortality in acute generalized peritonitis (AGP) is the development of multiple organ insufficiency. The intestine is the organ where the first changes develop in this pathology. The aim of the study – to research and evaluate the morphological changes in the small intestine wall of animals with experimental AGP. Materials and Methods. 32 white rats were used in this study. Acute peritonitis was modeled by introduction of 10 % fecal suspension in the dosage of 0.5 ml per 100 g of the animal's weight into the abdominal cavity of rats by puncture. The terms of observation: the 1st, 3rd and the 7th days from the beginning of the peritonitis modeling. For histological study the intestinal tissue was taken. The resulting pieces of the organ were fixed in a 10 % neutral formalin solution, which were then stained with hematoxylin and eosin. Results and Discussion. On the 3rd day of the experiment in animals with a modeled AGP, vascular changes were manifested first of all by the rounding (retraction) of endothelial cells or their desquamation and the appearance of defects, that allow plasma proteins and the formed elements of blood to leave circulation boundaries of the vascular bed. On the 7 th day in animals with a modeled AGP increased vascular permeability of the mucous membrane of the small intestine was accompanied by a significant edema of the stroma of the villi and by focal hemorrhages. Conclusion. Consequently, the distinct inflammatory changes in all terms of the injury were seen in the wall of the small intestine at the simulated AGP. The significant expansion of the capillaries and venules against the background of inflammatory infiltration in the stroma of the glandular component of the small intestine was noted on the 1st day from the beginning of the experiment. An increase in the height of intestinal villus and a crypt with retraction and desquamation of endothelial cells in the wall of vessels, which caused platelet adhesion in the areas of destruction was observed on the 3rd day. The areas of focal necrosis of the superficial epithelium, which were accompanied by multiple hemorrhages per diapedesis in the perivascular space of the mucous membrane, were seen in the wall of the small intestine of animals with a simulated AGP on the 7th day.

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