scholarly journals Serous borderline ovarian tumors: modern possibilities of ultrasound diagnostics in monitoring the course of the disease after organ-preserving operations

2021 ◽  
Vol 23 (1) ◽  
pp. 106-111
Author(s):  
Irina I. Davydova ◽  
Marina A. Chekalova ◽  
Apollon I. Karseladze ◽  
Viktor V. Kuznetsov ◽  
Liudmila A. Meshcheriakova ◽  
...  
Keyword(s):  
Malignant Tumors ◽  
Optimal Operation ◽  
Ovarian Tumors ◽  
Reproductive Age ◽  
Computer Assisted ◽  
Malignant Neoplasms ◽  
Ultrasound Method ◽  
Borderline Ovarian Tumors ◽  
Ultrasound Diagnostics ◽  
Wide Range

Relevance. Borderline ovarian tumors (BOT) occur mainly in women of reproductive age and account for 20% of all neoplasms of the female genital organs. Currently, there is an increase in the incidence of ВОТ. One of the reasons for the increase in morbidity is the improvement of knowledge and experience in relation to the morphological diagnosis of tumors of low malignancy potential. Nevertheless, the results of a preliminary instrumental assessment of the nature of the disease and the final diagnosis formed by histological examination are not always satisfactory, since borderline tumors are a thin layer that occupies an intermediate position between benign and malignant tumors. And, in spite of the fact that ВОТ is an independent nosological form in the histological classification, nevertheless, they have signs of both benign and malignant neoplasms. In this regard, the complexity of both instrumental and morphological diagnostics of ВOT becomes understandable, and, therefore, difficulties arise in determining the tactics of treatment, choosing the optimal operation, and the need for drug therapy. All these issues are directly related to the patients quality of life, and, most importantly, to survival. Because an incorrectly established diagnosis entails incorrect treatment and unsatisfactory results. Thus, the study of the peculiarities of ВOT diagnostics is extremely important. The ultrasound computed tomography method is simple, relatively cheap and affordable. Considering that almost all patients with ovarian neoplasms undergo this type of examination, it is extremely important and interesting to assess the role of the ultrasound method in the diagnosis of ВОТ. Moreover, at present more and more gynecological oncologists are resorting to organ-preserving surgical interventions for ВOТ. Therefore, it is especially important to study the possibility of ultrasound diagnostics in monitoring the course of the disease after breast-conserving operations, identifying recurrences of the disease in the ovary, differentiating recurrence and cystic formations of the ovaries. Aim. To determine the effectiveness of computer-assisted ultrasound diagnostics in monitoring the course of BOT after breast-conserving operations. Materials and methods. At Blokhin National Medical Research Center of Oncology carried out a retrospective and prospective analysis of 405 patients with serous BOT for the period 19702013. The age of the patients varied in a wide range, the minimum was 15, the maximum was 78 years, the median corresponded to 38 years. Before the start of treatment, the patients underwent an ultrasound examination (ultrasound) of the abdominal organs, the pelvic organs and the retroperitoneal space. The studies were carried out on expert ultrasonic systems Siemens ACUSON S2000, Hitachi ARIETTA V70 and Philips EPIQ 5. Results. We studied the capabilities of the ultrasound method for diagnosing serous BOT based on the analysis of morpho-ultrasound comparisons in patients after conservative and ultra-conservative operations. Conclusion. It has been established that ultrasound diagnostics is of decisive importance both in the initial diagnosis and in the dynamic observation of patients with conservative and ultra-conservative surgery for serous BOT. Echography makes it possible to diagnose a tumor in the ovary in 83.3% of cases and to reject the diagnosis in 86.7% of cases.

scholarly journals Clinicopathological analysis of ovarian tumours: a 10 year retrospective study

2018 ◽  
Vol 7 (8) ◽  
pp. 3216
Author(s):  
Sahana N. Naik ◽  
Sunil Kumar K. S. ◽  
Girija B.
Keyword(s):  
Malignant Tumors ◽  
Female Genital Tract ◽  
Germ Cell Tumors ◽  
Mucinous Cystadenoma ◽  
Ovarian Tumors ◽  
Reproductive Age ◽  
Benign Tumors ◽  
Age Group ◽  
Epithelial Tumors ◽  
Neoplastic Lesions

Background: Ovarian tumors account for 30% of all cancers of female genital tract which represents the sixth most common cancer and fourth leading cause of death in women. The present study was done with an objective to determine the frequency and distribution of various ovarian tumors and to study their clinical and histopathological presentations.Methods: It is a retrospective observational study of patients with ovarian tumors subjected to surgery in the department of obstetrics and gynecology, SDM College of Medical Sciences and Hospital from January 2005 to December 2015.Results: There were 642 cases comprising of 77.7% of neoplastic lesions and 22.3% of non-neoplastic lesions. Majority of the ovarian tumors (83%) were seen in the age group of 20 to 50 years. Mean age for ovarian tumors was 38 years.  Among the neoplastic lesions 84% were benign, 14.2% were malignant and 1.8% were borderline tumors. Surface epithelial tumors were the commonest tumors (60.9%) followed by germ cell tumors (12.8%).  Serous cystadenoma was the most common benign tumors (47.1%) followed by mucinous cystadenoma (18.4%). Among the ovarian malignant tumors; serous cystadenocarcinoma was the most common (4.5%) followed by mucinous cystadenocarcinoma (2.6%). Chocolate cysts were the most common among the non-neoplastic lesions (36.4%).Conclusions: Ovarian neoplastic lesions were more common than non-neoplastic lesions. Benign ovarian tumors were common in reproductive age group.  The mean age of occurrence for ovarian tumor was 38 years. The most common neoplasm was surface epithelial tumors, of which serous tumors was the commonest. Chocolate cysts were the most frequently encountered histopathological finding among the non-neoplastic lesions.

scholarly journals Borderline ovarian tumors

2006 ◽  
Vol 14 (1-2) ◽  
pp. 62-63
Author(s):  
Katarina Mastilovic ◽  
Tatjana Ivkovic-Kapicl ◽  
Milica Zivaljevic ◽  
Jelka Rajovic ◽  
Dejan Nincic
Keyword(s):  
Surgical Treatment ◽  
Malignant Tumors ◽  
Young Patients ◽  
Ovarian Tumors ◽  
Disease Stage ◽  
Early Disease ◽  
Oncogenic Potential ◽  
Stage Of Disease ◽  
Borderline Ovarian Tumors ◽  
Early Disease Stage

Borderline ovarian tumors are classified between benign cystadenoma and malignant cystadenocarcinoma. They are characterized as malignant tumors by histopathological features, which make them different from the benign ones. These tumors are commonly diagnosed at the early disease stage. The treatment of these tumors is surgical. The prognosis depends on the stage of disease and histopahtological types. We present 10 patients operated at the Institute of Oncology Sremska Kamenica because of malignant tumors with low malignant oncogenic potential in the period between 2000 and 2005. All patients had surgical treatment with ex tempore diagnostics, hysterectomy and adnexectomy with total omentectomy, or unilaterals adnexectomy. All patients had negative cytoanalytic findings of the small pelvis. Histopathological findings are necessary to confirm the diagnosis of disease. In young patients who had no children fertility can be preserved.

scholarly journals An age related study of morphology of human uterus

2016 ◽  
Vol 05 (01) ◽  
pp. 028-035
Author(s):  
Malamoni Dutta ◽  
H Bayan
Keyword(s):  
Morphological Changes ◽  
Reproductive Age ◽  
Basic Knowledge ◽  
Malignant Neoplasms ◽  
Age Group ◽  
Mean Values ◽  
Age Related ◽  
Wide Range ◽  
Significant Difference ◽  
Reproductive Age Group

Abstract Background and aims: The uterus is subjected to a wide range of normal variation in both its anatomy and physiology e.g. the changes of childhood to puberty and into the reproductive years, the variations of menstrual cycle, the changes consequent to pregnancy and parturition and fmally regression associated with menopause and postmenopausal years. It is a very important organ of female reproductive system and is subjected to investigation for size, shape and position in cases of infertility. The study of normal morphological architecture is of prime importance to have the basic knowledge of the various pathological entities. Materials and methods : 30 samples each from reproductive and postmenopausal women were collected from fresh unembalmed human cadavers. Biometrical values of the two different groups were recorded and statistically analyzed for Mean. The 'z' test was employed to find out the significant difference between mean values of length, breadth, thickness and weight. Results: The Length, Breadth , Thickness and weight of uterus in Reproductive age group and Post - menopausal age group differ significantly. The length, breadth, thickness and weight ranged from 6.2-9.0 em, 4.9-6.1 em, 2-3.5 em, 35.4-73 gm respectively in reproductive age group. In the postmenopausal group the length, breadth, thickness and weight ranged from 3.8-6.5 em, 1.8-5.0 em, 1-2.3 em, 18-40.0 gm respectively. Conclusion: A clear conception of the age related morphological changes ofuterus is a prerequisite for the radiologists for pelvic imaging and for clinicians for diagnosis and management of various diseases like benign and malignant neoplasms and infertility.

scholarly journals Forms of sternal reconstruction in oncology

2021 ◽  
Vol 180 (2) ◽  
pp. 57-62
Author(s):  
A. A. Kurilchik ◽  
V. S. Usachev ◽  
V. E. Ivanov ◽  
A. L. Starodubtsev ◽  
A. L. Zubarev
Keyword(s):  
Chest Wall ◽  
Malignant Tumors ◽  
Surgical Techniques ◽  
Successful Outcome ◽  
Malignant Neoplasms ◽  
Special Importance ◽  
Metastatic Tumors ◽  
Chest Wall Tumors ◽  
Wide Range ◽  
Sternal Reconstruction

INTRODUCTION. Chest wall tumors represent a variety of morphological forms and variants of lesions. According to different authors, primary malignant tumors of the chest wall account for 0.2–2 % of all malignant neoplasms. Of them, soft tissue sarcomas constitute about 45 %. Metastatic tumors of the chest wall occur much more frequently and most commonly develop from malignant tumors of the mammary, prostate and thyroid glands, lungs, kidneys and ovaries.MATERIALS AND METHODS. The standard of the treatment of primary and metastatic tumors of the chest wall is combination or comprehensive therapy. In some cases, preoperative care allows to create a more favorable environment for performing surgical treatment being considered the best option for chest wall tumors. The choice of a technique for the replacement of the post-resection chest wall defect is of special importance to preserve the physiological chest volume, to restore chest rigidity, to prevent paradoxical respiration and to seal the pleural cavity.RESULTS. There are different surgical techniques for skeleton reconstruction. A wide range of materials used for a skeleton reconstruction include bone tissues obtained from patient’s own body (bone autoplasty, autografts), polymeric mesh (polypropylene, polytetrafluoroethylene (Gore-Tex), bone cement (polymethyl methacrylate), stainless steel and titanium constructions as well as titanium bars and rib clips (STRATOS). In spite of a large number of techniques for sternal reconstruction described in the literature, searching for new materials and ways of their usage appears relevant.CONCLUSION. Our clinical case studies demonstrate that modern reconstructive techniques combined with careful surgical planning allow to perform radical surgery with a successful outcome preventing serious postoperative complications.

scholarly journals The influence of clinical, pathological and surgical factors on the occurrence of recurrence of borderline ovarian tumors in different age groups

2019 ◽  
Vol 15 (2) ◽  
pp. 57-61
Author(s):  
F. V. Novikov ◽  
V. P. Bondarev ◽  
E. S. Mishina ◽  
M. V. Mnikhovich
Keyword(s):  
Age Groups ◽  
Reproductive Function ◽  
Ovarian Tumors ◽  
Reproductive Age ◽  
High Survival ◽  
Non Invasive ◽  
Borderline Ovarian Tumors ◽  
First Case ◽  
Biological Potential

Background. Borderline ovarian tumors (BOT), due to their unclear biological potential, remain a problem for oncogynecologists. On the one hand, frequent recurrences of tumors, and on the other hand, a high survival rate in the diagnosis of patients requires careful weighing of all risk factors when choosing surgical intervention tactics in patients with BOT. A large number of recurrences of BOT in patients of fertile age lead to disability of patients, deterioration of their quality of life and loss of reproductive function.Objective: evaluation of the influence of clinical and morphological factors (the presence of non-invasive implants, bilateral lesion of the ovaries, the presence of psammous bodies and malignization tricks) and surgical factors (damage to the cyst capsule and carrying out fertility preserving operations) on the recurrence of BOT in various age groups.Materials and methods. The material for the study was the protocols of an in vivo pathoanatomical study of a biopsy (surgical) material obtained from patients with a diagnosis of BOT for the period from 2000 to 2017 inclusive, according to the Regional Forensic Medical Bureau of Kursk. A total of 110 protocols for the first occurrence of BOT and 14 protocols for the tumor recurrences were analyzed. The age of patients undergoing an in vivo pathologic examination ranged from 19 to 75 years.Results and conclusions. It has been revealed that psammous bodies, fertility preserving operations and reproductive age are associated with tumor recurrence. Groups of patients with foci of malignancy and bilateral lesions have a lower risk of BOT recurrence due to the radical surgical treatment tactics and possibly the use of chemotherapy in the first case. Non-invasive implants are not associated with the risk of BOT recurrence.

scholarly journals Clinicopathological importance of survivin immunoexpression in reproductive age patients with serous borderline ovarian tumors

2021 ◽  
Vol 46 (4) ◽  
pp. 1401-1408
Author(s):  
Erdem ŞAHİN ◽  
Hulya AKGUN ◽  
Yusuf MADENDAĞ ◽  
Mehmet Mete KIRLANGIÇ ◽  
Erol KARAKAŞ ◽  
...  
Keyword(s):  
Ovarian Tumors ◽  
Reproductive Age ◽  
Borderline Ovarian Tumors

scholarly journals Assessment of early symptoms of surgical menopause in patients with borderline ovarian tumors

2020 ◽  
Vol 14 (3) ◽  
pp. 269-282
Author(s):  
A. Yu. Vlasina ◽  
A. G. Solopova ◽  
A. E. Ivanov ◽  
I. M. Zhalyalova
Keyword(s):  
Treatment Group ◽  
Young Women ◽  
Ovarian Tumors ◽  
Reproductive Age ◽  
Anxiety And Depression ◽  
Early Symptoms ◽  
Radical Treatment ◽  
Borderline Ovarian Tumors ◽  
Surgery Group ◽  
Surgical Menopause

Aim: to make a comparative evaluation of women with borderline ovarian tumors (BOTs) and surgical menopause (early symptoms) and explore their level of anxiety and depression depending on the age and volume of surgery.Materials and methods. The prospective comparative study included 117 patients, aged 44.3 ± 6.5 years, after surgical treatment of BOTs: 62 women at reproductive age with surgical menopause after radical treatment (group IА), 24 women at reproductive age after organ-preserving surgery (group IВ), 31 women at perimenopausal age after radical treatment (group II). The severity of menopausal syndrome (modified menopausal Kupperman–Uvarova index), anxiety and depression (Hospital Anxiety and Depression Scale, HADS) were determined 29–59 (36.4 ± 5.6) days after surgery.Results. Early symptoms of surgical menopause are found in 98.3 % of patients with BOTs. Reproductive age patients after radical surgery (group IA) had moderate neurovegetative (21.7 ± 4.0 points), mild metabolic (5.8 ± 1.8 points), and moderate psychoemotional disorders (8.9 ± 1.4 points). Young women who underwent organ-saving operations with preservation of at least one ovary (group IB), had normal range the indicators of neurovegetative disorders (8.2 ± 3.1 points), metabolic and psychoemotional disorders were regarded as moderate (2.6 ± 1.6 and 5.9 ± 2.3 points, respectively). Disorders due to surgical menopause (early symptoms) at perimenopausal age females (group II) corresponded to a mild degree: neurovegetative – 15.3 ± 2.7 points; metabolic – 6.0 ± 2.2 points; psychoemotional – 5.7 ± 1.5 points. Our data indicate that patients of group IA had moderate surgical menopause (early symptoms) – 36.4 ± 5.4 points, while in groups IB and II the total values were 16.8 ± 5.4 and 27.0 ± 4.3 points, which corresponds to mild severity. Patients with BOTs (one month after antitumor therapy) had early symptoms of surgical menopause (postovariectomy syndrome). The most typical clinical picture was observed among young women after removal of both ovaries.Conclusion. Surgical menopause affects by somatic and psychological health negatively. This leads to a significant decrease in the quality of life and an increase in the level of disability among patients with gynecological cancer. Therefore, even at the planning treatment, it is necessary to include pre-rehabilitation measures to minimize the negative consequences of cancer therapy.

scholarly journals Data Set for the Reporting of Ear and Temporal Bone Tumors: Explanations and Recommendations of the Guidelines From the International Collaboration on Cancer Reporting

2018 ◽  
Vol 143 (5) ◽  
pp. 593-602 ◽  
Author(s):  
Ruta Gupta ◽  
Ann Sandison ◽  
Bruce M. Wenig ◽  
Lester D. R. Thompson
Keyword(s):  
Temporal Bone ◽  
International Collaboration ◽  
Malignant Tumors ◽  
Evidence Base ◽  
Malignant Neoplasms ◽  
Data Set ◽  
3 Dimensional ◽  
Wide Range ◽  
Collaborative Efforts ◽  
Cancer Reporting

The International Collaboration on Cancer Reporting (ICCR) was established to internationally unify and standardize the pathologic reporting of cancers based on collected evidence, as well as to allow systematic multi-institutional intercountry data collection to guide cancer care in the future. Such collaborative efforts are particularly essential for developing an evidence base for rare neoplasms or those with marked geographic variation in incidence, such as the tumors of the ear and the temporal bone. The ear and the temporal bone, including the external auditory canal and the middle and inner ear, with the closely associated facial nerve, internal carotid artery, and internal jugular vein, is one of the most complex anatomic structures in the head and neck. A wide range of benign and malignant neoplasms arise in this region. The management of these neoplasms involves complex surgery because of the anatomic confines, and as such, both benign and malignant tumors are included in this data set, as the oncologically equivalent management requires a multidisciplinary approach and standardized nomenclature and terminology. Surgical procedures at this site result in multifaceted 3-dimensional specimens that can be difficult to handle at macroscopic exam. A comprehensive macroscopic examination is important for identifying critical prognostic factors and often requires clinical and radiologic correlation. Histologic examination is straightforward for basal cell or squamous cell carcinoma but can be quite challenging for other neoplasms. A summary of the ICCR guidelines for ear tumors is presented, along with discussion of the salient evidence and practical issues.

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