Dynamics of symptoms of genitourinary menopausal syndrome and the frequency of recurrence of lower urinary tract infection in women in periand postmenopausal patients with combined therapy with Trioginal®

GYNECOLOGY ◽  
2018 ◽  
Vol 20 (6) ◽  
pp. 67-72
Author(s):  
D Yu Pushkar ◽  
M Yu Gvozdev

Material and methods. The study included patients (n=164) in peri- and postmenopause, having a laboratory-confirmed picture of the genitourinary menopausal syndrome - atrophic vulvovaginitis and suffering from recurrent lower urinary tract infections (UTI) - cystitis and urethritis. All patients underwent standard antibacterial therapy (ABT) UTI in accordance with the results of bacteriological urine culture according to Russian clinical guidelines on urology. Against the background of ABT, 164 patients received additional therapy with Trioginal® (the study group - SG) containing estriol, micronized progesterone and Lactobacillus casei rhamnosus Doderleini 35 (LCR 35) lactobacillus strain. Trioginal® was administered intravaginally in two stages: for 20 days, 2 capsules per day, then for 10 days, 1 capsule per day. In the comparison group - CG (n=67) with ABT, Ovipol Klio® (estriol monopreparation) was additionally intravaginally used in two stages: for 14 days, 1 suppository per day, then for 2 weeks, 1 suppository 2 times a week. The control group consisted of 30 patients receiving only standard ABT UTI, local hormone therapy for vulvovaginal atrophy (VVA) was not performed. The observation period was 12 months after the end of the course of therapy. At all stages of treatment, a subjective and objective assessment of the severity of urination disorders and urogenital atrophy (UDI-6 questionnaire), their impact on the quality of life of patients (questionnaire IIQ-7), indicators of bacteriuria, bacterial urine culture and vaginal biocenosis, frequency of undesirable phenomena were carried out. According to the initial characteristics of the group of patients were comparable. Results. At all stages of the study, in the group of patients who received therapy with the use of the Trioginal® drug, there was a significant improvement in the clinical picture of urination disorders compared to the CG and the control (main) group - MG (in SG - 18% at the end of therapy versus 100% before the start of therapy; CG - 26 % versus 100% respectively; Ledger - 58% versus 100% respectively; p

2012 ◽  
Vol 57 (No. 7) ◽  
pp. 380-383 ◽  
Author(s):  
S. Kralova-Kovarikova ◽  
R. Husnik ◽  
D. Honzak ◽  
P. Kohout ◽  
P. Fictum

Stenotrophomonas maltophilia was isolated from three dogs with lower urinary tract disorders. The bacterium was cultured from bladder wall biopsy specimens obtained during cystoscopy, whereas urine culture was negative in all cases. The culture of biopsy specimens is useful and may help with the therapy even if diagnosis of the primary disease has been made.    


Author(s):  
Chia-Hung Huang ◽  
Ying-Hsiang Chou ◽  
Han-Wei Yeh ◽  
Jing-Yang Huang ◽  
Shun-Fa Yang ◽  
...  

To investigate the association among lower urinary tract infection (UTI), the type and timing of antibiotic usage, and the subsequent risk of developing cancers, especially genitourinary cancers (GUC), in Taiwan. This retrospective population-based cohort study was conducted using 2009–2013 data from the Longitudinal Health Insurance Database. This study enrolled patients who were diagnosed with a UTI between 2010 and 2012. A 1:2 propensity score-matched control population without UTI served as the control group. Multivariate analysis with a multiple Cox regression model was applied to analyze the data. A total of 38,084 patients with UTI were included in the study group, and 76,168 participants without UTI were included in the control group. The result showed a higher hazard ratio of any cancer in both sexes with UTI (for males, adjusted hazard ratio (aHR) = 1.32; 95% confidence interval (CI) = 1.12–1.54; for females, aHR = 1.21; 95% CI = 1.08–1.35). Patients with UTI had a higher probability of developing new GUC than those without UTI. Moreover, the genital organs, kidney, and urinary bladder of men were significantly more affected than those of women with prior UTI. Furthermore, antibiotic treatment for more than 7 days associated the incidence of bladder cancer in men (7–13 days, aHR = 1.23, 95% CI = 0.50–3.02; >14 days, aHR = 2.73, CI = 1.32–5.64). In conclusion, UTI is significantly related to GUC and may serve as an early sign of GUC, especially in the male genital organs, prostate, kidney, and urinary bladder. During UTI treatment, physicians should cautiously prescribe antibiotics to patients.


Author(s):  
В. В. Третьяков ◽  
В. С. Мякотных

Для определения места и роли дегенеративных изменений поясничного отдела позвоночника в патогенезе синдрома нижних мочевых путей и успешности проведения лечебных мер наблюдали 106 мужчин пожилого и старческого возраста, страдающих доброкачественной гиперплазией предстательной железы и патологией позвоночника. Длительные хронические боли в пояснице испытывали 48 (45,3 %) пациентов, у 93,8 % из них отмечали никтурию, у 75 % - затруднения при мочеиспускании, у 60,4 % - ложные позывы на мочеиспускание, что мотивировало обращение к урологу. Выявленные с помощью опросника IPSS различия, соответственно 21,78±4,33 и 16,33±4,61 балла, указывали на негативное значение хронического болевого синдрома в формировании общей клинической картины урологической патологии. У лиц старческого возраста болевой синдром и симптомы раздражения мочевых путей были менее выраженными, чем у лиц пожилого возраста, а обструктивные симптомы, наоборот, более отчетливыми. Хронические болевые синдромы в поясничной области значительно чаще ( р <0,001)регистрировали у 67 пациентов с удовлетворительными и неудовлетворительными результатами лечения по поводу расстройств мочеиспускания, чем у 39 с наилучшей эффективностью. Таким образом, патология поясничного отдела позвоночника и связанные с ней хронические болевые синдромы вносят существенный вклад в патогенез и клиническую картину синдрома нижних мочевых путей и в результативность лечения расстройств мочеиспускания. Выявленные особенности следует учитывать в процессе диагностики и лечения комбинированной патологии. In order to determine the place and role of degenerative changes in the lumbar spine in the pathogenesis of lower urinary tract syndrome and the success of treatment measures, 106 elderly and senile male patients suffering from benign prostatic hyperplasia and spinal pathology were observed. Long-term chronic lower back pain was experienced by 48 (45,3 %) patients, 93,8 % of them had night urination, 75 % had difficulty urinating, and 60,4 % had false urge to urinate, which motivated them to contact a urologist.The differences identified using the IPSS questionnaire, respectively 21,78±4,33 and 16,33±4,61 points, indicated a negative value of chronic pain syndrome in the formation of the overall clinical picture of urological pathology. Among the senile patients, pain and urinary tract irritation symptoms were less pronounced than among the elderly patients, and obstructive symptoms, on the contrary, were more pronounced. Chronic pain syndromes in the lumbar region were significantly more frequent ( p <0,001) among 67 patients with satisfactory and unsatisfactory results of treatment for urination disorders than among 39 with the best efficiency. Thus, the pathology of the lumbar spine and associated chronic pain syndromes make a significant contribution to the pathogenesis and clinical picture of the lower urinary tract syndrome and to the effectiveness of treatment of urination disorders. The identified features should be taken into account in the process of diagnosis and treatment of combined pathology.


1983 ◽  
Vol 103 (2) ◽  
pp. 316-319 ◽  
Author(s):  
Linda Wallen ◽  
W. Patrick Zeller ◽  
Mary Goessler ◽  
Edward Connor ◽  
Ram Yogev

2017 ◽  
Vol 07 (05) ◽  
pp. 532-544
Author(s):  
Ayman Shehata Dawood ◽  
Abdelghaffar Said Dawood ◽  
Salah Abdelmonsef Nagla ◽  
Mohamed Abdelatti El-Bakary

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Zalina N ◽  
Aruku N ◽  
Azura N ◽  
Shahida N ◽  
Akhmarina N ◽  
...  

Introduction: Frequency of lower urinary tract symptoms (LUTS) in young age women is not well studied. It is said to be common among female elderly and multiparous population. The aim of this study is to obtain the prevalence of LUTS among nulliparous students in relation to their personal hygiene. Materials and methods: This is a prospective cross-sectional study conducted among  200 nulliparous medical and nursing students aged between 18-28 years using standardized questionnaires. Urine samples were also collected from students to detect urinary tract infections. Results: The complete data sets of 146 students were analyzed. All of them were nulliparous, single and not sexually active. The prevalence of LUTS was 52.7% consist of over-active bladder, urinary incontinence (UI) and voiding difficulty respectively (51.3%, 34.9% and 45.2%). The most common type of UI was stress urinary incontinence which was 21.9% followed by 11.6% of urgency incontinence. Conclusion: The prevalence of LUTS among young age population is high at 52.7%. Public awareness regarding LUTS and availability of treatment is needed.


2012 ◽  
Vol 119 ◽  
pp. S727-S727
Author(s):  
J. Renard ◽  
M.T. Da Quinta e Costa de Mascarenhas Sa ◽  
G.J. Wirth ◽  
M. Zahran ◽  
E. Quimper ◽  
...  

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