scholarly journals Bringing diversity of experience into decision-making about surgery: developing an app for that

2018 ◽  
Vol 5 (1) ◽  
Author(s):  
Ilja Ormel ◽  
Susan Law ◽  
Michel Lortie ◽  
Charles Onu ◽  
Donna Tataryn
Keyword(s):  
Breast Cancer ◽  
Decision Making ◽  
Recommender System ◽  
Specific Information ◽  
Breast Cancer Patients ◽  
Women’S Experiences ◽  
Women's Experiences ◽  
Novel Approach ◽  
Wide Range ◽  
Challenges And Opportunities

ObjectiveTo design and pilot a mobile application to support decision-making about surgery for breast cancer patients, drawing from a collection of narratives from a diverse sample of Canadian women that used video/audio recordings (published on www.healthexperiences.ca). BackgroundThis idea came from the results of a larger research project where we collected a wide range of women’s stories about having breast cancer using qualitative research methods and video/audio recording. The women we interviewed for this project said that they felt overwhelmed by the amount of information in the period between diagnosis and surgery, and at the same time they felt they needed more specific information relevant to their needs, personal situation and preferences. They also wanted to learn from other women’s experiences of surgery. This project therefore aims to develop an information tool that can respond to that need by offering information in a more personalized manner. This project is funded by the QBCF [Quebec Breast Cancer Foundation]. MethodsSecondary analysis of existing data. Development of recommender system. Design and evaluation involving patients, clinicians and informatics experts. ResultsWe will present our analysis regarding women’s experiences related to surgery, decision-making, preferences and expectations, and need for experiential information. We will then present the development to date of a personalized information application using a computerized recommender system, including a summary of challenges and opportunities encountered along the way. ConclusionDeveloping reliable, evidence-based tools and electronic applications based on other peoples’ experiences offers a novel approach to support informed healthcare decision-making.

Treatment decision making in breast cancer: A longitudinal exploration of women's experiences

2011 ◽  
Vol 17 (1) ◽  
pp. 155-170 ◽  
Author(s):  
Katherine Swainston ◽  
Carol Campbell ◽  
Anna van Wersch ◽  
Patricia Durning
Keyword(s):  
Breast Cancer ◽  
Decision Making ◽  
Treatment Decision ◽  
Women’S Experiences ◽  
Treatment Decision Making ◽  
Women's Experiences

Decision Support for Patients With Early-Stage Breast Cancer: Effects of an Interactive Breast Cancer CDROM on Treatment Decision, Satisfaction, and Quality of Life

2001 ◽  
Vol 19 (6) ◽  
pp. 1676-1687 ◽  
Author(s):  
Sjaak Molenaar ◽  
Mirjam AG Sprangers ◽  
Emiel J. Th. Rutgers ◽  
Ernest JT Luiten ◽  
Jan Mulder ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Decision Making ◽  
Early Stage ◽  
Treatment Decision ◽  
Early Stage Breast Cancer ◽  
Specific Information ◽  
Breast Cancer Patients ◽  
Decision Satisfaction

PURPOSE: To investigate the effects of the Interactive Breast Cancer CDROM as a decision aid for breast cancer patients with a choice between breast conserving therapy (BCT) and mastectomy (MT). PATIENTS AND METHODS: Consecutive patients with stage I and II breast cancer were enrolled. A quasi-experimental, longitudinal, and pretest/posttest design was used. Follow-up was scheduled 3 and 9 months after discharge from the hospital. Control patients (n = 88) received standard care (oral information and brochures). The CDROM was provided to patients in the experimental condition (n = 92) as a supplement to standard procedures. Outcome variables were treatment decision, satisfaction, and quality of life (QoL). RESULTS: No effect on treatment decision was found. CDROM patients expressed more general satisfaction with information at 3 and 9 months (95% confidence interval for the difference (d) between the means (d: 4.1 to 12.5 and 5.7 to 14.2 respectively). CDROM patients were also more satisfied with their treatment decision at 3 and at 9 months (d: 0.1 to 0.4; 0.2 to 0.5). Moreover, at 9 months, CDROM patients were more satisfied with breast cancer–specific information (d: 0.9 to 16.5), the decision-making process (d: 0.1 to 0.4), and communication (d: 0.2 to 11.0). At 3 and 9 months, a positive effect was found on general health (d: 0.2 to 14.5 and 0.3 to 15.0). Moreover, at 9 months, CDROM patients reported better physical functioning (d: 5.1 to 19.8), less pain (d: -17.9 to -4.5), and fewer arm symptoms (d: -14.1 to -0.5). CONCLUSION: The Interactive Breast Cancer CDROM improved decision making in patients with early-stage breast cancer with a choice between BCT and MT, as evaluated in terms of patients’ satisfaction and QoL.

Information needs of breast cancer patients and how educational status influence their information needs in Ghana

2021 ◽  
pp. 096100062098161
Author(s):  
Benedicta Boadi ◽  
George Tesilimi Banji ◽  
Patrick Adzobu ◽  
Stephen Okyere
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Health Information ◽  
Information Literacy ◽  
Information Needs ◽  
Educational Status ◽  
Health Facilities ◽  
Military Hospital ◽  
Specific Information ◽  
Breast Cancer Patients

Health information literacy plays a critical role in self-management practices among patients living with chronic health conditions. However, there are limited studies on information needs among breast cancer patients in Ghana. This paper therefore investigated the information needs of women living with breast cancer in Ghana and how educational status influenced their information needs. The study was conducted in two health facilities in Accra, Ghana (37 Military Hospital and Sweden Ghana Medical Centre). A total of 75 breast cancer patients were conveniently selected from the two health facilities for the study. The instrument used to elicit relevant data for this study was a questionnaire using the survey design. Data was analysed descriptively. The findings of the study revealed that the information needs of the breast cancer patients investigated were centred mainly around treatment and management information and less around preventive information. The patients also ranked diagnostic information as their highest need, followed by physical care information, treatment information, psychosocial information and disease-specific information in that order. Patients with higher education reported higher information need on all the five domains compared to those with lower education. The study therefore recommended that management of health facilities make health information literacy an integral component of their treatment and management of breast cancer.

scholarly journals Proteomic Analysis of Zeb1 Interactome in Breast Carcinoma Cells

Molecules ◽  
2021 ◽  
Vol 26 (11) ◽  
pp. 3143
Author(s):  
Sergey E. Parfenyev ◽  
Sergey V. Shabelnikov ◽  
Danila Y. Pozdnyakov ◽  
Olga O. Gnedina ◽  
Leonid S. Adonin ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Cells ◽  
Epithelial To Mesenchymal Transition ◽  
Critical Role ◽  
Malignant Neoplasm ◽  
Malignant Neoplasms ◽  
Breast Cancer Patients ◽  
Survival Prognosis ◽  
Mesenchymal Transition ◽  
Wide Range

Breast cancer is the most frequently diagnosed malignant neoplasm and the second leading cause of cancer death among women. Epithelial-to-mesenchymal Transition (EMT) plays a critical role in the organism development, providing cell migration and tissue formation. However, its erroneous activation in malignancies can serve as the basis for the dissemination of cancer cells and metastasis. The Zeb1 transcription factor, which regulates the EMT activation, has been shown to play an essential role in malignant transformation. This factor is involved in many signaling pathways that influence a wide range of cellular functions via interacting with many proteins that affect its transcriptional functions. Importantly, the interactome of Zeb1 depends on the cellular context. Here, using the inducible expression of Zeb1 in epithelial breast cancer cells, we identified a substantial list of novel potential Zeb1 interaction partners, including proteins involved in the formation of malignant neoplasms, such as ATP-dependent RNA helicase DDX17and a component of the NURD repressor complex, CTBP2. We confirmed the presence of the selected interactors by immunoblotting with specific antibodies. Further, we demonstrated that co-expression of Zeb1 and CTBP2 in breast cancer patients correlated with the poor survival prognosis, thus signifying the functionality of the Zeb1–CTBP2 interaction.

The relationship of self-acceptance with decision making duration in cancer patient to perform mastectomy

2021 ◽  
pp. 1-5
Author(s):  
Ayu Ratuati Setiawan ◽  
Feny Tunjungsari ◽  
Mochamad Aleq Sander
Keyword(s):  
Breast Cancer ◽  
Decision Making ◽  
Cancer Patients ◽  
Breast Cancer Patients ◽  
Cross Sectional ◽  
Abnormal Growth ◽  
Self Acceptance ◽  
Observation Method ◽  
Relationship Of ◽  
The Relationship

BACKGROUND: Cancer is a disease caused by abnormal growth of body cells that turn malignant and continue to grow uncontrollably. One of the treatments for breast cancer is mastectomy. The quickness of decision-making determines the survival rate of prognosis patients. OBJECTIVE: This study aimed to determine the relationship of self-acceptance with decision-making duration in cancer patients to perform a mastectomy. METHODS: An analytic observation method with cross-sectional design. The samples were taken by purposive sampling method with 50 samples of breast cancer patients. Data collected include age, last level of education, marital status, profession, stage of cancer during mastectomy, self-acceptance score, and decision-making duration to perform a mastectomy. RESULTS: The data analyzed with the Kruskal–Wallis test. The test showed the relationship of self-acceptance (p = 0.027) with decision-making duration in breast cancer patients to perform a mastectomy. CONCLUSION: In Conclusion, there is a relationship of self-acceptance with decision-making duration in breast cancer patients to perform a mastectomy.

Against all odds: Australian women’s experiences of recovery from breast cancer

2010 ◽  
Vol 19 (17-18) ◽  
pp. 2531-2538 ◽  
Author(s):  
Rakime Elmir ◽  
Debra Jackson ◽  
Barbara Beale ◽  
Virginia Schmied
Keyword(s):  
Breast Cancer ◽  
Women’S Experiences ◽  
Women's Experiences
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