Vaccine Targeted Prophylaxis For Covid-19: A Comprehensive Review

2021 ◽  
Vol 12 (3) ◽  
pp. 1850-1860
Author(s):  
Sonia Goswami ◽  
Nagarajan K ◽  
Praveen K. Dixit ◽  
Vidhu Saxena ◽  
Richa Goel ◽  
...  

The Severe acute respiratory syndrome coronavirus-2, the contamination that prompts sickness19(covid-19), has spread quickly from the initially known cases in china in December 2019 to nations round the globe. On March 10,2020, the world health organization reported that there have been 113,702 affirmed instances of corona virus -19 round the globe, additionaly to 4,012 passing. Due to this worldwide well being emergency analysts are handling build up a corona virus immunization. Protected and compelling immunizations are going to be a game changer: yet for years to return we should always wearing covers, genuinely separating and staying faraway from swarms. Being inoculated doesn't imply that we will laugh in the face of any potential risk and put ourselves as well as other people in danger, especially in light of the very fact that it is as yet not satisfactory what proportions the antibodies can ensure against sickness also as against contamination and transmission. Vaccine for corona virus are basic devices for managing the pandemic when joined with compelling testing and existing anticipation measures. The general undertaking to form a secure and effective coronavirus vaccine is proving to be fruitful. A handful of vaccines now are authorized round the globe, may more in development. Antibodies save an excellent many lives per annum.

Author(s):  
Hirad Abtahi

Abstract Since COVID-19 was declared a pandemic by the World Health Organization, the International Criminal Court (ICC) has taken a series of measures to ensure the continuation of its activities. To this effect, the Court has adjusted its proper administration both in Headquarters and Country Offices by moving to (partial) virtual offices mode. In so doing, the ICC has striven to ensure that staff well-being and business continuity go hand in hand. On this basis, the Court has worked towards the execution of its mandate, i.e. the prosecution and trial of individuals alleged to have committed one or more of the ICC Statute crimes. Against this background, the Court has had recourse to a combination of technological and sanitary measures in order to conduct pre-trial, trial and appeals proceedings in a fair and expeditious manner. These proceedings have ranged from the execution of arrest warrants and transfer of suspects to the Court’s custody through to the holding of hearings in the courtroom. By adapting itself to the evolving nature of COVID-19 — and reactions to the virus — the ICC will ensure that it remains resilient in the face of this unprecedented global sanitary crisis.


Author(s):  
GANGAPRASAD ANANTRAO WAGHMARE

 Coronaviruses (CoV) are a large family of viruses that cause illness ranging from the common cold to more severe diseases such as Middle East Respiratory Syndrome (MERS-CoV) and Severe Acute Respiratory Syndrome (SARS-CoV). In more severe cases, infection can cause pneumonia, severe acute respiratory syndrome, kidney failure and even death   Initially, the World Health Organization (WHO) had mentioned 2% as a mortality rate estimate in a press conference on Wednesday, January 29 and again on February 10. However, on January 29 2020 WHO specified that this was a very early and provisional estimate that might have changed. 3.4% Mortality Rate estimate by the World Health Organization (WHO) as of March 3 2020.                           The concept of epidemic was very much well defined in Ayurveda, Acharya Charaka the great physician of all ages had mentioned the epidemic diseases under the heading of “Janapadodhwans”.The aim of this review study is to understand the ancient Ayurveda epidemic literature , to prevent people from getting affected by epidemic diseases and to enlighten on epidemic diseases prevention & Management through Ayurveda. Keywords: Novel corona Virus (2019-nCoV),severe acute respiratory syndrome,Janapadodhwans,Ayurveda,epidemic Diseases,communicable disease,Panchakarma, Rasayan .  


Author(s):  
Prahlad Kadambi

Severe acute respiratory syndrome coronavirus 2 is currently spreading globally rapidly. The World Health Organization (WHO) named the virus as the 2019 novel corona virus (2019-nCoV) on January 7, 2020. On February 11th 2020, the illness associated was named as 2019 coronavirus disease (COVID-19). Subsequently, the WHO declared COVID-19 as a pandemic on 11 March 2020. The first case of COVID-19 was reported in India on 30 January 2020 in Thrissur, Kerala. This was the index case in India who tested positive after coming for a vacation. This individual was a student of the University of Wuhan. Subsequent cases were reported in Kerala. Subsequently, the number of cases in India increased to 519 as on 24th March 2020 with mortality in 7 patients as on 22nd March 2020 and 10 patients on 24th March 2020.


2021 ◽  
Vol 21 (4) ◽  
pp. 1509-17
Author(s):  
Ismaila Emahi ◽  
Mimmie CNC Watts ◽  
Samuel Azibere ◽  
Joseph F Morrison ◽  
Kwabena AN Sarpong

Corona virus disease 2019 (COVID-19) remains an incurable, progressive pneumonia-like illness characterized by fever, dry cough, fatigue, and headache during its early stages. COVID-19 has ultimately resulted in mortality in at least 2 million people worldwide. Millions of people globally have already been affected by this disease, and the numbers are expected to increase, perhaps until an effective cure or vaccine is identified.Although Africa was initially purported by the World Health Organization (WHO) to be severely hit by the pandemic, Africa recorded the least number of cases during the first wave, with lowest rates of infections, compared to Asia, Europe, and the Americas. This statistic might be attributed to the low testing capacity, existing public health awareness and lessons learnt during Ebola epidemic. Nonetheless, the relatively low rate of infection should be an opportunity for Africa to be better prepared to overcome this and future epidemics.In this paper, the authors provide insights into the dynamics and transmission of the severe acute respiratory syndrome corona virus (SARS-CoV-2) during the first wave of the pandemic; possible explanations into the relatively low rates of infection recorded in Africa; with recommendations for Africa to continue to fight Covid-19; and position itself to effectively manage future pandemics. Keywords: Covid-19; Ebola; Science Leadership in Africa; Vaccine; SARS-COV-2; Preventative Health; Future Pandemics.


2020 ◽  
Vol 24 (3) ◽  
pp. 201-206
Author(s):  
R. Kodidala Satyanath ◽  
J. Sorout ◽  
S. Jayachandra ◽  
A. Gandhi ◽  
S. Kacker

There is a new public health crises threatening globally with the emergence and spread of 2019 novel corona virus (COVID-19) or the severe acute respiratory syndrome corona virus 2 (SARS-CoV-2). In very recent decade we have seen endemic outbreaks in the form of Middle East respiratory syndrome coronavirus (MERS CoV) and severe acute respiratory syndrome related coronavirus (SARS-CoV). Now we again see the emergence of another serious outbreak due to a new strain called the SARS-CoV-2 virus. This SARS-CoV-2 initially presented as pneumonia of unknown etiology with group of symptoms including fever, dry cough and shortness of breath in a cluster of patients in December 2019 Wuhan, China. COVID-19 now has quickly became a health emergency now across worldwide. SARS-CoV-2 is a newly emerging human infectious corona virus that causes COVID-19, now this has been recognized as a pandemic by the World Health Organization (WHO) on 11th March, 2020. Because of the pathogenesis and proliferation pathways of COVID-19 are still unknown the development of vaccine was not developed yet and definitive treatment was not implemented. Therefore, in this article, new potential COVID-19 therapies are briefly reviewed. The world is in emergent need for searching of possible medications for COVID-19.


Author(s):  
MONAJI SANJANA REDDY

Severe acute respiratory syndrome corona virus-2 (SARS-CoV-2) is another name given to pandemic disease COVID-19 that is caused by a newly discovered coronavirus. People infected with coronavirus will experience mild-to-moderate respiratory illness, and it can be seen in a serious stage when comorbidities include along with it. This is now creating a huge pandemic situation all over the world with a huge rate of sufferers, that is, around 9.06 million around the world and about 440 k in India till today according to the World Health Organization. This is a serious condition that should be solved with vaccine only as coronavirus is undergoing mutation it makes difficult to invent a vaccine for it. So far, about 200 genetic mutations have been discovered across the world also in these 198 mutations appeared independently more than once. Due to this pandemic situation, there are so many clinical trials going on in discovering vaccines. Recently, after many trails conducting favipiravir are found to be the most successful in treating any stage of SARS-CoV-2. This article focuses completely on this area, along with its mechanism, side effects, uses, and contraindications.


2020 ◽  
Vol 11 (SPL1) ◽  
pp. 748-752
Author(s):  
Swapnali Khabade ◽  
Bharat Rathi ◽  
Renu Rathi

A novel, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), causes severe acute respiratory syndrome and spread globally from Wuhan, China. In March 2020 the World Health Organization declared the SARS-Cov-2 virus as a COVID- 19, a global pandemic. This pandemic happened to be followed by some restrictions, and specially lockdown playing the leading role for the people to get disassociated with their personal and social schedules. And now the food is the most necessary thing to take care of. It seems the new challenge for the individual is self-isolation to maintain themselves on the health basis and fight against the pandemic situation by boosting their immunity. Food organised by proper diet may maintain the physical and mental health of the individual. Ayurveda aims to promote and preserve the health, strength and the longevity of the healthy person and to cure the disease by properly channelling with and without Ahara. In Ayurveda, diet (Ahara) is considered as one of the critical pillars of life, and Langhana plays an important role too. This article will review the relevance of dietetic approach described in Ayurveda with and without food (Asthavidhi visheshaytana & Lanhgan) during COVID-19 like a pandemic.


JAMIA Open ◽  
2020 ◽  
Author(s):  
Srikar Chamala ◽  
Sherri Flax ◽  
Petr Starostik ◽  
Kartikeya Cherabuddi ◽  
Nicole M Iovine ◽  
...  

Abstract Coronavirus disease 2019, first reported in China in late 2019, has quickly spread across the world. The outbreak was declared a pandemic by the World Health Organization on March 11, 2020. Here, we describe our initial efforts at the University of Florida Health for processing of large numbers of tests, streamlining data collection, and reporting data for optimizing testing capabilities and superior clinical management. Specifically, we discuss clinical and pathology informatics workflows and informatics instruments which we designed to meet the unique challenges of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) testing. We hope these results benefit institutions preparing to implement SARS-CoV-2 testing.


Pathogens ◽  
2021 ◽  
Vol 10 (1) ◽  
pp. 32
Author(s):  
Giovanni Di Guardo

With over 80 million cases, and 1,800,000 deaths reported at the end of 2020 by the World Health Organization, the “CoronaVirus Disease-2019” (CoViD-19) pandemic, caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), should be viewed as a global catastrophe [...]


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