scholarly journals Microbial landscape and immune status in maxillary sinusitis of stomatogenic origin

2021 ◽  
Vol 26 (3) ◽  
pp. 145-151
Author(s):  
I.V. Kovach ◽  
S.D. Varzhapetian ◽  
Kh.A. Bunyatyan ◽  
O.E. Reyzvikh ◽  
A.A. Babenya ◽  
...  

Oroanthral fistula (anastomosis) is an element preventing the restoration of homeostasis in the maxillary sinus due to the constant flow of microbes from the oral cavity. It is also contributes to frequent exacerbations of maxillary sinusitis. Saprophytic gram-positive cocci and fungi of the oral cavity are dominating representatives of the microbial flora in the maxillary sinus. As the result of research, we found that in the case of maxillary sinusitis with oroantral fistula fungi made up 25.0% of microbiota, gram-positive bacteria – 41.7%, gram-negative bacteria – 33.3%. Gram-positive cocci from the Staphy­lococcus genus (Staphylococcus aureus and Staphylococcus epidermidis) and fungi (Candida albicans) comprised the biggest proportion of microbial flora that 33.3% and 16.7%, respectively. Slightly decreased levels of monocytes in venous blood was noted in 69.2% of patients. The average value of total serum IgE in group with oroantal fistula was 226.2 (70.4) IU/ml, the result exceeded normal limits almost in 2.26 times. Large circulating immune complexes (CICs) were normal in all patients in the group with iatrogenic maxillary sinusitis. The average lavels of small size CICs was 170.2 (4.23) ОU, which is in 1.06 times higher the upper limit of the norm (160 ОU). Elevated levels of total Ig E in serum of patients with oroanthral fistula indicates allergic sensitization. The detection of increased levels of CICs with small and medium sizes in serum may indicate a susceptibility of this category of patients to the development of immunopathological reactions.

2009 ◽  
Vol 56 (4) ◽  
pp. 201-206 ◽  
Author(s):  
Aleksa Markovic ◽  
Snjezana Colic ◽  
Radojica Drazic ◽  
Ljiljana Stojcev ◽  
Bojan Gacic

Oroantral fistula is pathologic communication between oral cavity and maxillary sinus, usually localized between antrum and buccal vestibulum. Persisting OAF always causes chronic maxillary sinusitis. A technique for closure of a large oroantral fistula with resorbable collagen membrane is described.


F1000Research ◽  
2014 ◽  
Vol 3 ◽  
pp. 81 ◽  
Author(s):  
Benjamin L. Hodnett ◽  
Berrylin Ferguson

Dental sources of infection can produce acute and chronic maxillary sinusitis. In some cases, the source of the infection may be related to the presence of endodontic materials in the oral cavity. In this article, we report a case of retained gutta-percha in the maxillary sinus resulting in chronic sinusitis.


2020 ◽  
pp. 1-3

Purpose of the study: To describe the management of orosinusal pathology by combined transnasal endoscopy and oral combined. Methods: The 54-year-old patient underwent a dental and otolaryngological evaluation for left odontogenic maxillary sinusitis in relation to plausible dental follicular cyst of ectopic element 2.8. The symptoms reported at the time of access to the hospital were nasal obstruction and nocturnal rhonchopathy. To the ENT evaluation in videorinoscopy with rigid optics, complex deviation of the nasal septum was relevated with not any evident formations or pathological secretions. While on inspection of the oral cavity the mucous membranes appeared unscathed. Alveolus of 1.6 previosuly extracted was evident. The radiological examination, facial CT, revealed the left maxillary sinus almost completely occupied by a cystic appearance, with thin calcified walls and homogeneous content that has a dental element, probably the 2.8, which fenestrates the vestibular cortex of the lateral wall of the maxillary sinus. This lesion erodes the medial wall of the sinus, obliterating the ostio-meatal complex and imprinting the ipsilateral ethmoidal cells. Biohumoral tests showed normal coagulation parameters, indices of renal function, liver and ionemia. The patient under general anesthesia and oral intubation with a combined intervention of the left anterior FESS, intrasulcular flap from dental elements 2.7 to 2.3 with mesial releasing incision, moderate osteotomy, ectopic 2.8 extraction and enucleation of the cystic lesion with simultaneous closure of the orosinusal communication with advancement of the Bichat adipose bolla and closure by first intention. In the same session, the ENT moment is carried out trans nasally for total left uncinectomy, medium antrostomy with the union of the natural ostium and the accessory ostium. Bilateral lower turbinoplasty with bipolar forceps. The patient was then controlled after 15 days and six months, showing good healing and no signs of recurrence at the rhinoscopic check on the physical examination of the oral cavity. Results: based on the clinical and radiological aspect, the diagnosis of a follicular dentigerous cyst (WHO 2017) covered by a multi-layered non-keratinized paving epithelium, with moderate chronic inflammation, including gigantocellular and cholesteric crystals, is reached from the microbiological and histological examination. Necrotic amorphous material coexists including rare hyphae and fungal spores, with therefore mycotic and actinomycotic super infection. Conclusions: The combined oral and nasal intervention, allowed by the collaboration between the oral surgeon and ENT, has made it possible to shorten the healing time and to resolve the pathology without any sign of recurrence.


1973 ◽  
Vol 36 (3) ◽  
pp. 143-145 ◽  
Author(s):  
J. S. Lee ◽  
D. K. Pfeifer

Aerobic microbial flora, moisture, and NaCl contents of smoked salmon samples, obtained from retail outlets along the roast of the Pacific Northwest, were examined. The microbial loads ranged from 1.3 × 102 to 2.2 × 106. The moisture level were from 48 to 64%, and the water phase salts from 3.2 to 8.2. Regularly recoverable microorganisms in most samples were gram-positive cocci. They were either mostly staphylococci micrococci, depending on the sample. Bacillus, Pseudomonas, and yeasts were predominant in some samples. The gram-positive cocci were able to grow in 10 to 25% NaCl, but the majority of them did not multiply at 4 C and were readily inactivated by mild heat (D52C of 1.5 to 47.9 min).


Author(s):  
Eugênio Braz Rodrigues Arantes

ResumoA fístula ou comunicação bucossinusal consiste na formação de um trajeto direto entre a cavidade oral e o seio maxilar diagnosticada tardiamente após epitelização da mucosa formando um canal bucossinusal permanente. Na maioria das vezes, essa complicação ocorre em função da relação anatômica do seio maxilar intimamente relacionado com o ápice das raízes dos dentes superiores posteriores. Procedimentos cirúrgicos inadequados relacionados à exodontia dos elementos dentários envolvidos ou extensa pneumatização do seio maxilar podem ser as causas mais comuns dessa patologia. O objetivo do presente trabalho é apresentar um relato de caso clínico de uma fístula bucossinusal pós exodontia e não corrigida imediatamente, tratada através de retalho mucoso palatino vascularizado e rotacionado para fechamento primário. A técnica do retalho palatino mostrou-se uma opção favorável para o fechamento do defeito sinusal em um único tempo cirúrgico, preservando a mucosa queratinizada e a anatomia do sulco vestibular.Palavras-chave: Seio maxilar, sinusite maxilar, fístula bucoantral, cirurgia bucal.AbstractThe bucosinusal fistula or communication consists in the formation of a direct path between the oral cavity and the maxillary sinus diagnosed late after epithelialization of the mucosa forming a permanent bucosinusal canal. Most often, this complication occurs due to the anatomical relationship of the maxillary sinus closely related to the apex of the roots of the posterior superior teeth. Inadequate surgical procedures related to the extraction of the involved dental elements or extensive pneumatization of the maxillary sinus may be the most common causes of this pathology. The aim of the present study is to present a case report of an immediately uncorrected post-extraction bucosinusal fistula treated with a vascularized palatine mucous flap and rotated for primary closure. The palatal flap technique proved to be a favorable option for closing the sinus defect in a single surgical time, preserving the keratinized mucosa and the buccal sulcus anatomy.Key-words: Maxillary sinus, maxillary sinusitis, oroantral fistula, oral surgery.


2016 ◽  
Vol 10 (1) ◽  
pp. 261-267
Author(s):  
Tsutomu Sugiura ◽  
Kazuhiko Yamamoto ◽  
Chie Nakashima ◽  
Kazuhiro Murakami ◽  
Yumiko Matsusue ◽  
...  

We report a case of chronic maxillary sinusitis caused by denture lining material entering through an oroantral fistula after tooth extraction. The patient was an 80-year-old female who visited us with a complaint of pus discharge from the right posterior maxilla. She had extraction of the upper right second molar and had her upper denture relined with silicone lining material. The patient noticed swelling of the right cheek and purulent rhinorrhea 20 days before her first visit to our clinic. Oral examination showed an oroantral fistula with a diameter of 3 mm in the posterior alveolar ridge of the right maxilla. Computed tomography revealed a hyperdense foreign body in the right maxillary sinus and thickening of the mucosal lining. Under diagnosis of maxillary sinusitis caused by a foreign body, endoscopic maxillary surgery was performed simultaneously with the removal of the foreign body. The foreign body removed was 12 × 6 mm in size, oval in shape, light pink in color, and compatible with silicone denture lining material. During the follow-up it was observed that the oroantral fistula closed spontaneously after the removal of the foreign body. The maxillary sinus was in a good shape without recurrence of sinusitis seven months after surgery.


2012 ◽  
Vol 2012 ◽  
pp. 1-4 ◽  
Author(s):  
Yunus Feyyat Şahin ◽  
Togay Muderris ◽  
Sami Bercin ◽  
Ergun Sevil ◽  
Muzaffer Kırıs

Foreign bodies in maxillary sinuses are unusual clinical conditions, and they can cause chronic sinusitis by mucosal irritation. Most cases of foreign bodies in maxillary sinus are related to iatrogenic dental manipulation and only a few cases with non-dental origin are reported. Oroantral fistulas secondary to dental procedures are the most common way of insertion. Treatment is surgical removal of the foreign body either endoscopically or with a combined approach, with Caldwell-Luc procedure if endoscopic approach is inadequate for visualisation. In this case, we present a 24-year-old male patient with unilateral chronic maxillary sinusitis due to a wooden toothpick in left maxillary sinus. The patient had a history of upper second premolar tooth extraction. CT scan revealed sinus opacification with presence of a foreign body in left maxillary sinus extending from the floor of the sinus to the orbital base. The foreign body, a wooden toothpick, was removed with Caldwell-Luc procedure since it was impossible to remove the toothpick endoscopically. There was no obvious oroantral fistula in the time of surgery, but the position of the toothpick made us to think that it was inserted through a previously healed fistula, willingly or accidentally.


2019 ◽  
Vol 33 (5) ◽  
pp. 500-506 ◽  
Author(s):  
Chi Sang Hwang ◽  
Chunui Lee ◽  
Hee Sung Chae ◽  
Chun Han ◽  
Hyun Woo Yang ◽  
...  

Background Bisphosphonates are widely used as bone stabilizers, which can cause major side effects including bisphosphonate-related osteonecrosis of the jaw (BRONJ) that occurs more frequently in the mandible. Consequently, there is a need for a detailed investigation of BRONJ of the maxilla and, in particular, of involvement of the maxillary sinus. Objective Our aim was to evaluate the characteristic radiologic and clinical manifestations in patients with maxillary sinusitis and a history of long-term bisphosphonate use. Methods Between January 2015 and July 2018, 55 patients with symptoms consistent with chronic rhinosinusitis who underwent a paranasal sinus computed tomography (CT) and had a history of >12 months of bisphosphonate therapy were included in the analysis. Results Radiologically and clinically evident chronic rhinosinusitis was noted in 24 of the 55 patients, of whom more than half (14/24, 58.3%) had BRONJ. The CT studies demonstrated that the maxillary sinus was involved in all 24 patients, characterized by unilateral involvement (70.8%) and bony remodeling in the posterior maxillary region (90.5%). The evidence of osteitis on CT and/or single-photon emission CT was observed in the majority of cases (19/21, 90.5%) and 12 patients (50.0%) had oroantral fistula. However, there were no differences in the clinical appearance of the diseases with respect to the radiologic aspects. Conclusions Besides its well-known effects on the mandible, long-term bisphosphonate use can also affect the maxillary sinus, with typical clinical and radiological manifestations.


Sinusitis ◽  
2021 ◽  
Vol 5 (1) ◽  
pp. 53-58
Author(s):  
Yasutaka Yun ◽  
Masao Yagi ◽  
Tomofumi Sakagami ◽  
Shunsuke Sawada ◽  
Yuka Kojima ◽  
...  

Odontogenic maxillary sinusitis (OMS) is a disease in which inflammation from the teeth extend into the maxillary sinus, causing symptoms of unilateral sinusitis. OMS can recur, with some being resistant to antibiotics. In intractable cases, exodontia and endoscopic sinus surgery (ESS) are necessary treatments. Here we report our analysis on the indications for surgical intervention in cases diagnosed with and treated as OMS. We retrospectively examined 186 patients who were diagnosed with sinusitis on a computed tomography (CT) scan. For cases diagnosed with OMS, the site of the causative tooth and the presence or absence of oroantral fistula to the maxillary sinus was examined. In addition, we analyzed the therapeutic efficacy of the initial treatment of antibiotics, and what the indications were for ESS. Among the patients examined, OMS was diagnosed in 44 cases (23.6%). In 14 out of 20 cases that underwent a post-medical treatment CT scan, OMS found to be treatment-resistant. Of these 14 cases, 12 (88%) had oroantral fistulae to the maxillary sinus. In all cases where exodontia, fistula closure surgery, and endoscopic sinus surgery (ESS) were performed, the fistula disappeared and the shadow of inflammation in the paranasal sinus improved. In OMS with oroantral fistula, ESS, exodontia, and fistula closure should be recommended over medication such as macrolide therapy.


2018 ◽  
Vol 19 (3) ◽  
Author(s):  
Anna Kędzia ◽  
Elżbieta Hołderna-Kędzia ◽  
Joanna Wiśniewska

Introduction. Therapeutical, cosmetical and culinary properties of lavender oil was valued from ancient. Lavandula angustifolia Mill. (Lavandula officinalis Chaix.) belonging to the family Lamiaceae. Lavender produced essential oil. It possess different property: hepatoprotective, antidiabetic, antispasmotic, antiulcers, antidepression, antioxidant, antireumatic, insect repellent and antimicrobial. Aim. The aim of this work was to investigate the susceptibility of anaerobes of oral cavity to lavender oil. Material and methods. The anaerobic bacteria were isolated from various infections of oral cavity. A total 32 strains of bacteria isolated from patients and 5 reference strains were examined. The susceptibility (MIC) anaerobes to lavender oil was determined by means of plate dilution technique in Brucella agar, supplemented with 5% defibrynated sheep blood, menadione and hemin. Stock solution of essential oil was prepared in dimethylsulfoxide (DMSO) and afterwords in distilled water. Concentration of oil used were: 0.12, 0.25, 0.5, 1.0 and 2.0 mg/ml. The inoculum contained 106 CFU per spot was seeded with Steers’ replicator upon the surface of agar with oil and without the oil (strains growth control). Incubation was performed in anaerobic conditions in anaerobic jars, at 37°C for 48 hrs. The MIC was interpreted as the lowest concentration of lavender oils inhibiting the growth of tested anaerobic bacteria. Results. The results indicated, that from all tested anaerobes 10 (31%) was susceptible in ranges < 0.12-0.5 mg/ml. The oil was active towards 53% strains in concentration = 1.0 mg/ml. The MIC for remaining strains was > 2.0 mg/ml. From the Gram-positive cocci the most susceptible were the strains Peptostreptococcus anaerobius. MIC of the strains were < 0.12 mg/ml. The Gram-positive rods were the lowest sensitive. The lavender oil inhibited growth of this bacteria in concentration = 1.0 mg/ml. Conclusions. The more susceptible to lavender oil, from Gram-negative bacteria were the genus Bacteroides vulgatus, Bacteroides uniformis and from Gram-positive cocci genus Peptostreptococcus anaerobius. The Gram-negative anaerobes were less susceptible to tested oil than Gram-positive anaerobic bacteria.


Sign in / Sign up

Export Citation Format

Share Document