scholarly journals Effects of Different Hemodialysis Treatments on Abnormal Mineral and Bone Metabolism in Patients with Chronic Renal Failure

2020 ◽  
Vol 4 (6) ◽  
Author(s):  
Qiang Li
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Bone Metabolism ◽  
Type I ◽  
High Flux ◽  
Blood Calcium ◽  
Amino Terminal ◽  
Group A ◽  
The Difference ◽  
Group B

Objective: To investigate the effects of different hemodialysis treatments on abnormal mineral and bone metabolism in patients with chronic renal failure. Methods: A random number table was used to divide 80 patients with chronic renal failure admitted to our hospital from January 2018 to January 2019 into 2 groups, with 40 cases in each group. Group A was treated with low-flux hemodialysis, and group B was treated with high-flux hemodialysis. The related indicators of mineral and bone metabolism of the two groups were compared. Results: Before treatment, the blood calcium, blood phosphorus, intact parathyroid hormone (iPTH), type I procollagen amino terminal peptide (PINP), fibroblast growth factor 23 (FGF23), serum creatinine (Scr) indicators of the two groups were compared. The difference was not statistically significant(P>0.05); After treatment, the blood calcium levels of the two groups were higher than before treatment, the blood phosphorus, iPTH, PINP, FGF23, and Scr levels were lower than before treatment, and the blood calcium level of group B was higher than that of group A, while blood phosphorus, iPTH, PINP, FGF23, and Scr levels were lower than group A, the difference was statistically significant (P<0.05). Conclusion: Compared with low-flux hemodialysis, patients with chronic renal failure treated with high-flux hemodialysis have better results, which can correct abnormal bone metabolism and improve Scr levels.

Hormonal profile in pubertal females with chronic renal failure: Before and under haemodialysis and after renal transplantation

1987 ◽  
Vol 115 (3) ◽  
pp. 289-296 ◽  
Author(s):  
Jorge R. Ferraris ◽  
Horacio M. Domene ◽  
Maria E. Escobar ◽  
Maria G. Caletti ◽  
Jose A. Ramirez ◽  
...  
Keyword(s):  
Renal Failure ◽  
Renal Transplantation ◽  
Chronic Renal Failure ◽  
Tanner Stage ◽  
Breast Development ◽  
Hormonal Profile ◽  
Serum Lh ◽  
Group A ◽  
Pubertal Stages ◽  
Group B

Abstract. The effects of chronic renal failure on the hypothalamic-pituitary-ovarian axis in 25 girls, aged 9.1 to 20.9 years (mean 13.8) were studied. Twelve patients on conservative treatment (group A) had serum creatinine values between 176.8 and 1502.8 μmol/l; 9 patients were on haemodialysis (group B); and 12 patients had received a renal transplant (group C). Tanner stage of breast development was delayed relative to chronological age in 5 out of 18 patients. Serum oestradiol was normal or low when related to pubertal stages in all groups. Serum LH was elevated in group A and B patients, but normal in group C patients. Serum FSH was elevated in 6 out of the 21 patients in group A plus B, and in 2 out of the 12 patients in group C. Serum PRL was elevated in 12/12, 6/8, and 4/11 patients in group A, B, and C respectively. After GnRH administration to 4 patients in group A, 3 showed delayed or absent gonadotropin response; all 4 patients studied in group C showed normal gonadotropin response. The data indicate a decreased E2 secretion, abnormal gonadotropin and PRL levels and a blunted gonadotropin response to GnRH in girls with chronic renal failure. These results seem to indicate an alteration of the hypothalamic-pituitary unit that can be reversed after successful renal transplantation.

scholarly journals Psoriatic Arthritis Is an Indicator of Significant Renal Damage in Patients with Psoriasis: An Observational and Epidemiological Study

2017 ◽  
Vol 2017 ◽  
pp. 1-6 ◽  
Author(s):  
Abidullah Khan ◽  
Iqbal Haider ◽  
Maimoona Ayub ◽  
Mohammad Humayun
Keyword(s):  
Renal Failure ◽  
Renal Function ◽  
Psoriatic Arthritis ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Increased Risk ◽  
Chi Squared ◽  
Group A ◽  
The Difference ◽  
Group B

Background. Psoriasis affects joints in around 30% of the patients. Recent studies have demonstrated an increased risk of essential hypertension, ischemic heart disease, and stroke in psoriatic patients. However, the prevalence of renal disease in patients with psoriasis has not been evaluated properly.Objectives. Objectives were to evaluate renal functions in patients with psoriasis and to assess any possible relationship of renal failure with psoriasis and psoriatic arthritis.Methods. In this cross-sectional study, 30 participants were recruited into the following three groups: group-A, psoriatic arthritis; group-B, psoriasis without arthritis; and group-C, healthy subjects. Renal function tests were performed for every participant of each group. The data was analyzed by using SPSS version 16. Chi-squared and one-way ANOVA tests were applied, considering aPvalue of less than 0.05 as a standard criterion.Results. Serum creatinine, urea, and phosphate were the highest in group-A, higher in group-B, and normal in group-C,P<0.05. Similarly, GFR was the lowest in group-A, lower in group-B, and normal in group-C. The difference in mean GFR values was statistically significant,F(2)=355,P<0.001. Moreover, proteinuria (gm/day) was seen in 96.7% of the patients with psoriatic arthritis, (M=1.18±0.55,P<0.05) against 10% of the psoriatic patients without arthritis (M=0.41±0.10,P<0.05).Conclusion. Derangement of renal function is more prevalent in psoriatic patients, especially in those with concomitant psoriatic arthritis. Therefore, each psoriatic patient must be routinely screened for an underlying renal failure.

scholarly journals Pattern of Lipid Profile in Chronic Renal Failure Patient with GFR < 60 ml/min/1.73 m2 on Conservative Treatment Versus Maintenance Haemodialysis

2016 ◽  
Vol 27 (2) ◽  
pp. 55-61
Author(s):  
Md Daharul Islam ◽  
Mohammad Rafiqul Islam ◽  
SM Tajdit Rahman ◽  
Khaleda Akhter ◽  
Adiba Tarannum ◽  
...  
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Conservative Treatment ◽  
Lipid Profile ◽  
Chronic Renal Failure Patient ◽  
Renal Failure Patient ◽  
Maintenance Haemodialysis ◽  
Stage 4 ◽  
Group A ◽  
Group B

The incidence and prevalence of chronic kidney disease (CKD) are increasing worldwide and are associated with poor outcomes. It becomes apparent that the severity of CKD along with CVD severity in any population makes a devastated combination for both patients and healthcare system. Identification of CKD as a major risk factor for cardiovascular morbidity and mortality is attributed to dyslipidemia, and therefore an expectation of effective intervention to diminish premature cardiovascular mortality and progression of renal disease to increase longevity is imperative, thus this study may explore the lipid profile in chronic renal failure patient; on conservative treatment and maintenance haemodailysis treatment. A cross sectional comparative study was carried out to find out the Pattern of lipid profile in chronic renal failure patient with GFR < 60 ml/min on conservative treatment versus maintenance haemodialysis admitted in a selected hospital of Dhaka city. Total 128 study population were selected according to selection criteria among which 62 subjects were on maintenance dialysis (designated as group A) and 66 subjects were on conservative treatment of CKD (designated as group B). On average cholesterol, LDL and triglyceride level were more in group B than group A. On the other hand, HDL level was more in group A than group B and it was statistically insignificant. At the same time average LDL/HDL ratio was higher in group B than group A. But all these differences were statistically insignificant. Among the group A patients average triglyceride, total cholesterol and LDL level were higher in stage 4 CKD patients than stage 5 CKD patients. Average HDL level was higher in stage 5 CKD patients than stage 4 CKD patients. Among the group B patients average triglyceride and LDL level were higher in stage 4 CKD patients. But none of these two differences were statistically significant. On the other hand, average total cholesterol level was higher in stage 3 CKD patients and it was statistically significant(p<0.05). HDL level was higher in stage 5 patients. But this difference was not statistically significant. In group A LDL/HDL ratio was more in stage 4 CKD patients and it was statistically significant(p<0.05). Average LDL/HDL ratio was highest in stage 4 CKD patients in group B and it was statistically significant (p<0.05). Our study had showed that mean lipid profile is better in patients of CKD on dialysis than those on conservative treatment, but there is no statistical significance as sample size very small. A multicentric prospective study involving larger number of study population giving adequate statistical power is recommended for conclusive comment on the possible factors associated with dyslipidaemia in CKD patients.Bangladesh J Medicine Jul 2016; 27(2) : 55-61

THE INFLUENCE OF CHRONIC RENAL FAILURE ON SERUM AND URINARY THYROID HORMONE LEVELS

1978 ◽  
Vol 89 (1) ◽  
pp. 80-88 ◽  
Author(s):  
Klaus Kølendorf ◽  
Birger Broch Møller ◽  
Preben Rogowski
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Statistical Significance ◽  
Thyroid Stimulating Hormone ◽  
Serum Free ◽  
Total Triiodothyronine ◽  
Total Thyroxine ◽  
Group A ◽  
Uptake Test ◽  
Group B

ABSTRACT The effects of various degrees of chronic renal failure on serum and urinary thyroid hormones were studied in 10 patients with a mean creatinine clearance (Cr.Cl.) of 23 ml/min (group A), in 11 patients with a Cr.Cl. of 5.7 ml/min (group B), and in 60 healthy euthyroid subjects with normal renal function. We found a significant decrease (P < 0.01) of serum total thyroxine (T4) (5.3 ±1.9 (sd) μg/100 ml in group A and 4.1 ± 1.5 in group B), serum total triiodothyronine (T3) (65.4 ± 17.4 ng/100 ml ~57.4 ± 13.9), serum free T4 (5.60 ± 1.74 arb.U ∼ 4.45 ± 1.61), and serum free T3 (69.51 ± 21.22 arb.U ∼ 62.09 ± 12.39). T3 uptake test and basal thyroid stimulating hormone (TSH) values were normal in both groups of renal patients. No statistical significance was found in T4 excretion in urine. Urinary T3 excretion was significantly reduced (P < 0.01) in group A (27 ± 44 ng/24 h), and undetectable in terminal renal failure. Urinary protein excretion was non-selective and low (median 0.2 g/24 h and 0.7 g/24 h, respectively). Conclusively we have found reduced levels of serum total and free T3, and in contradiction to most investigators substantially reduced levels of serum total and free T4. Urinary excretion of T4 and T3 reflects the low levels of free serum hormones and the tubular impairment.

CT-guided microcoil localization of pulmonary nodules: the effect of the position of microcoil proximal end on the incidence of microcoil dislocation

2021 ◽  
Author(s):  
Zhen-Guo Huang ◽  
Cun-li Wang ◽  
Hong-liang Sun ◽  
Shu-Zhu Qin ◽  
Chuan-Dong Li ◽  
...  
Keyword(s):  
Chest Wall ◽  
Pleural Cavity ◽  
Pulmonary Nodules ◽  
Type I ◽  
Type Ii ◽  
Ct Guided ◽  
Group A ◽  
The Difference ◽  
Group B ◽  
Wall Group

Objectives: To evaluate the effect of the position of microcoil proximal end on the incidence of microcoil dislocation during CT-guided microcoil localization of pulmonary nodules (PNs). Methods: This retrospective study included all patients with PNs who received CT-guided microcoil localization before video-assisted thoracoscopic urgery (VATS) resection from June 2016 to December 2019 in our institution. The microcoil distal end was less than 1 cm away from the nodule, and the microcoil proximal end was in the pleural cavity (the pleural cavity group) or chest wall (the chest wall group). The length of microcoil outside the pleura was measured and divided into less than 0.5 cm (group A), 0.5 to 2 cm (group B) and more than 2 cm (group C). Microcoil dislocation was defined as complete retraction into the lung (type I) or complete withdrawal from the lung (type II). The rate of microcoil dislocation between different groups was compared. Results: A total of 519 consecutive patients with 571 PNs were included in this study. According to the position of microcoils proximal end on post-marking CT, there were 95 microcoils in the pleural cavity group and 476 in the chest wall group. The number of microcoils in group A, B, and C were 67, 448 and 56, respectively. VATS showed dislocation of 42 microcoils, of which 30 were type II and 12 were type I. There was no statistical difference in the rate of microcoil dislocation between the pleural cavity group and the chest wall group (6.3% vs 7.6%, x2 = 0.18, p = 0.433). The difference in the rate of microcoil dislocation among group A, B, and C was statistically significant (11.9%, 5.8%, and 14.3% for group A, B, and C, respectively, x2 = 7.60, p = 0.008). In group A, 75% (6/8) of dislocations were type I, while all eight dislocations were type II in group C. Conclusions: During CT-guided microcoil localization of PNs, placing the microcoil proximal end in the pleura cavity or chest wall had no significant effect on the incidence of microcoil dislocation. The length of microcoil outside the pleura should be 0.5 to 2 cm to reduce the rate of microcoil dislocation. Advances in knowledge: : CT-guided microcoil localization can effectively guide VATS to resect invisible and impalpable PNs. Microcoil dislocation is the main cause of localization failure. The length of microcoil outside the pleura is significantly correlated with the rate and type of microcoil dislocation. Placing the microcoil proximal end in the pleura cavity or chest wall has no significant effect on the rate of microcoil dislocation.

Comparative Study of effectiveness of mobilization with movement (MWM) and End range mobilization (ERM) techniques in frozen shoulder

2018 ◽  
Vol 4 (4) ◽  
pp. 519-522
Author(s):  
Jeyakumar S ◽  
Jagatheesan Alagesan ◽  
T.S. Muthukumar
Keyword(s):  
Range Of Motion ◽  
Frozen Shoulder ◽  
Type I ◽  
Mean Values ◽  
Functional Activities ◽  
Group A ◽  
The Mean ◽  
Group B

Background: Frozen shoulder is disorder of the connective tissue that limits the normal Range of motion of the shoulder in diabetes, frozen shoulder is thought to be caused by changes to the collagen in the shoulder joint as a result of long term Hypoglycemia. Mobilization is a therapeutic movement of the joint. The goal is to restore normal joint motion and rhythm. The use of mobilization with movement for peripheral joints was developed by mulligan. This technique combines a sustained application of manual technique “gliding” force to the joint with concurrent physiologic motion of joint, either actively or passively. This study aims to find out the effects of mobilization with movement and end range mobilization in frozen shoulder in Type I diabetics. Materials and Methods: 30 subjects both male and female, suffering with shoulder pain and clinically diagnosed with frozen shoulder was recruited for the study and divided into two groups with 15 patients each based on convenient sampling method. Group A patients received mobilization with movement and Group B patients received end range mobilization for three weeks. The outcome measurements were SPADI, Functional hand to back scale, abduction range of motion using goniometer and VAS. Results: The mean values of all parameters showed significant differences in group A as compared to group B in terms of decreased pain, increased abduction range and other outcome measures. Conclusion: Based on the results it has been concluded that treating the type 1 diabetic patient with frozen shoulder, mobilization with movement exercise shows better results than end range mobilization in reducing pain and increase functional activities and mobility in frozen shoulder.

Efficacy and Safety of Oral Ivermectin and Topical Permethrin in the Treatment of Scabies

2020 ◽  
Vol 33 (1) ◽  
pp. 41-47
Author(s):  
Mohsena Akhter ◽  
Ishrat Bhuiyan ◽  
Zulfiqer Hossain Khan ◽  
Mahfuza Akhter ◽  
Gulam Kazem Ali Ahmad ◽  
...  
Keyword(s):  
Skin Diseases ◽  
Close Contact ◽  
Randomized Study ◽  
Sarcoptes Scabiei ◽  
Efficacy And Safety ◽  
Common Skin ◽  
Group A ◽  
The Mean ◽  
The Difference ◽  
Group B

Background: Scabies is one of the most common skin diseases in our country. It is caused by the mite Sarcoptes scabiei var hominis, which is an ecto-parasite infesting the epidermis. Scabies is highly contagious. Prevalence is high in congested or densely populated areas. Individuals with close contact with an affected person should be treated with scabicidal which is available in both oral and topical formulations. The only oral but highly effective scabicidal known to date is Ivermectin. Amongst topical preparations, Permethrin 5 % cream is the treatment of choice. Objective: To evaluate the efficacy & safety of oral Ivermectin compared to topical Permethrin in the treatment of scabies. Methodology: This prospective, non-randomized study was conducted at the out-patient department of Dermatology and Venereology of Shaheed Suhrawardy Medical College & Hospital over a period of 6 months, from August 2016 to January 2017. The study population consisted of one hundred patients having scabies, enrolled according to inclusion criteria. They were divided into two groups. group A was subjected to oral Ivermectin and the group B to Permethrin 5% cream. Patients were followed up on day 7 and 14 for assessment of efficacy and safety. Result: The mean scoring with SD in group A (Ivermectin) and group B (Permethrin) were 8.26 ± 2.22 and 7.59 ± 2.01 respectively at the time of observation. The difference between the mean score of the two group is not significant (p=0.117) the mean scoring with SD in group A and group B were 4.54 ± 2.05 and 1.64 ± 1.84 respectively at 7thdays. The difference between the mean score of the two group is significant (p<0.001). The mean scoring with SD in group A and group B were 2.68± 2.35 and .36± 1.10 respectively at 14th day difference between the mean score of the group is significant (p<0.001). Conclusion: Topical application of permethrin 5% cream is more effective and safer than oral Ivermectin in the treatment of scabies. TAJ 2020; 33(1): 41-47

Effect of Sample Storage Conditions on Body Burden Analysis of Organic Contaminants in Unionid Mussels

1992 ◽  
Vol 27 (4) ◽  
pp. 833-844 ◽  
Author(s):  
Micheline Hanna
Keyword(s):  
Organic Contaminants ◽  
Body Burden ◽  
Storage Conditions ◽  
The Body ◽  
Sample Storage ◽  
Pcb Congeners ◽  
Unionid Mussels ◽  
Group A ◽  
The Difference ◽  
Group B

Abstract In order to quantitatively assess the effect of sample storage conditions on the body burden analysis of organic contaminants, a comparative analysis was carried out on the unionid mussel Elliptic complanata. The mussels were divided into two groups, each with distinct storage conditions, while Group A was kept in the freezer at −20°C, Group B was kept in the refrigerator for five days at 5°C. All the compounds present in the control were also present in Group B samples. Analysis of the organic contaminants in each of these two groups showed that for total PCB concentrations, the two treatments were not significantly different; however when compared individually 6 of the 13 PCB congeners showed significant differences. The observed differences were relatively small for individual PCB congeners (7.1 to 15.3%), higher for chlorobenzenes (10.5 to 36.4%), and yet higher for HCE (44.1%); the difference for HCE, although large is nevertheless not significant, even if only marginally so.

scholarly journals The Pandemic and Changes in the Self-Perception of Teacher Digital Competences of Infant Grade Students: A Cross Sectional Study

2021 ◽  
Vol 18 (9) ◽  
pp. 4756
Author(s):  
Rosalía Romero-Tena ◽  
Carmen Llorente-Cejudo ◽  
María Puig-Gutiérrez ◽  
Raquel Barragán-Sánchez
Keyword(s):  
Intervention Group ◽  
Cross Sectional Study ◽  
Self Perception ◽  
Digital Competence ◽  
Cross Sectional ◽  
Self Perceptions ◽  
Group A ◽  
Different Dimensions ◽  
The Difference ◽  
Group B

Without having a reaction time, the pandemic has caused an unprecedented transformation in universities around the world, leading to a revolution from structured models anchored in the conception of transmission of training towards a teaching approach-learning saved thanks to the incorporation of technology. This study aims to verify whether the pandemic situation has influenced the digital competence self-perception of students. Comparing two groups during the academic years 2019/2020 and 2020/2021, the instrument used is the questionnaire for digital competence “DigCompEdu Check-In” for future teachers. After the educational intervention, group A (before COVID-19) presented higher self-perceptions of competence than group B (during COVID-19); the pandemic situation caused by COVID-19 has negatively influenced students’ self-perception of their digital skills in the pretest in the different dimensions under study. Before receiving the training, the group that did not experience the pandemic enjoyed a higher self-perception of their competencies than the group that experienced the pandemic. The data obtained indicate that the difference exists, and that it is statistically significant, and may be a consequence of the clear relationship between self-perception and the way in which students face reality through their personal and subjective vision.

Does body position, age, and heart rate induce IOP’s changes?

2021 ◽  
pp. 112067212110233
Author(s):  
Marcelina Sobczak ◽  
Magdalena Asejczyk ◽  
Malwina Geniusz
Keyword(s):  
Heart Rate ◽  
Body Position ◽  
Age Groups ◽  
Cardiovascular Parameters ◽  
Entire Cohort ◽  
Significant Difference ◽  
Group A ◽  
The Difference ◽  
Group B ◽  
Effect Of Age

Objectives: The main goal of this research was to determine the differences between the values of intraocular pressure (IOP) in the supine and sitting positions, and to assess the effect of age and cardiovascular parameters. Methods: Seventy-two healthy adults were enrolled and classified into age groups: 20–30 years (group A), 31–40 years (group B), and 41–71 years (group C). Corneal biometry and cardiovascular parameters, such as heart rate (HR), were measured. IOP measurements were taken in the sitting position (IOPS) and in the supine position (IOPL) using the iCare® Pro tonometer. Results: A significant difference between the IOPS and IOPL in the entire cohort was found ( p < 0.001). Regarding the age subgroups, a significant difference ( p < 0.001) between the IOPS and IOPL was obtained in group A (2.6 ± 1.6 mmHg) and group C (1.5 ± 1.3 mmHg). There were no significant differences in the IOPS between groups. The highest IOP values were obtained for group A. The correlations between HR and IOPS are statistically significant for group A and group B, and for HR and IOPL-S for group B only. Multivariate analysis showed that HR has a significant influence on the difference in IOP in the two body positions. Conclusion: A statistically significant difference between the effect of age and the values of IOPS and IOPL was shown. Cardiovascular parameters showed some relevant statistical dependencies, but with a rather marginal significance in young people. The influence of body position for the measurement of IOP for healthy subjects does not seem to matter, despite the fact that there are some dependencies that are statistically significant.

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