scholarly journals Complete Thoracoscopic Segmentectomy and Pulmonary Lobectomy in the Treatment of Small Pulmonary Nodules

2021 ◽  
Vol 5 (6) ◽  
pp. 57-60
Author(s):  
Yu Zhou
Keyword(s):  
Clinical Effect ◽  
Pulmonary Nodules ◽  
Clinical Effects ◽  
Pulmonary Lobectomy ◽  
Significant Difference ◽  
Postoperative Drainage ◽  
Group A ◽  
Treatment Safety ◽  
Group B ◽  
Small Pulmonary Nodules

Objective: To compare the clinical effect of complete thoracoscopic segmentectomy and pulmonary lobectomy for pulmonary nodules. Methods: In this study, 176 patients with pulmonary nodules were treated in Changshu Hospital Affiliated to Nanjing University of Chinese Medicine from January 2019 to June 2021; according to the type of surgery, the patients were divided into group A (complete thoracoscopic segmentectomy) and group B (complete thoracoscopic pulmonary lobectomy), and the clinical effects were analyzed. Results: The intraoperative blood loss, postoperative drainage volume, postoperative hospitalization days, and lung function of patients in group A were significantly better than those in group B (P < 0.05), while there was no significant difference in the number of dissected lymph nodes. Conclusion: The clinical effect of complete thoracoscopic segmentectomy for patients with small pulmonary nodules is more significant; it does not only ensure lymph node dissection, but also improve surgical-related indicators and treatment safety as well as speed up the recovery of pulmonary function. Its clinical application value is worthy of key analysis by medical institutions.

scholarly journals Clinical effect analysis of laminectomy alone and laminectomy with instrumentation in the treatment of TOLF

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Zhi-Wei Wang ◽  
Zheng Wang ◽  
Yan-Hong Zhou ◽  
Jia-Yuan Sun ◽  
Wen-Yuan Ding ◽  
...  
Keyword(s):  
Clinical Effect ◽  
Clinical Effects ◽  
Cross Sectional ◽  
Improvement Rate ◽  
Duration Of Symptoms ◽  
Residual Rate ◽  
Score Improvement ◽  
Significant Difference ◽  
Group A ◽  
Group B

Abstract Background To explore the clinical effect of laminectomy alone and laminectomy with instrumentation in the treatment of TOLF. Methods A retrospective study was conducted on the clinical data of 142 patients with TOLF and laminectomy who underwent spine surgery at XXX Medical University from January 2003 to January 2018. According to whether the laminectomy was combined with instrumentation, the patients were divided into two groups: group A (laminectomy alone (LA), n = 77) and group B (laminectomy with instrumentation (LI), n = 65). Comparisons of possible influencing factors of demographic variables and operation-related variables were carried out between the two groups. In this study, the clinical effects of LA and LI in the treatment of TOLF were discussed. Thus, we explored the clinical effect of LA and LI in the treatment of TOLF. Results In terms of demographics, there was a statistically significant difference in BMI between group A and group B (P < 0.05). The differences in age, sex, smoking, drinking, heart disease, hypertension and diabetes were not statistically significant (P > 0.05). In terms of preoperative symptoms, there was a significant difference in gait disturbance, pain in the LE, and urination disorder between group A and group B (P < 0.05), but there was no significant difference in other variables between the two groups (P > 0.05). In terms of operation-related variables, there was a significant difference in the preoperative duration of symptoms, intramedullary signal change on MRI, dural ossification, residual rate of cross-sectional spinal canal area on CT, shape on the sagittal MRI, operation time, pre-mJOA, post-mJOA at 1 year, and leakage of cerebrospinal fluid between group A and group B (P < 0.05), but there was no significant difference in other variables between the two groups (P > 0.05). The preoperative average JOA score of group A was 6.37 and that of group B was 5.19. In group A, the average JOA score at 6 months, 1 year and 2 years after surgery was 7.87, 8.23 and 8.26, respectively, and the average JOA score improvement rate was 32.79 %, 38.32 and 38.53 %, respectively. In group B, the average JOA score at 6 months, 1 year and 2 years after surgery was 7.74, 8.15 and 8.29, respectively, and the average JOA score improvement rate was 39.15 %, 46.86 and 47.12 %, respectively. Conclusions Currently, there is no consensus on whether instrumentation is needed after laminectomy for TOLF. We found that for patients with a long duration of gait disturbance, urination disorder, preoperative duration of symptoms, intramedullary signal change on MRI, dural ossification, residual rate of cross-sectional spinal canal area on CT less than 60 %, and shape on the sagittal MRI being beak and low, pre-mJOA had better clinical effects after LI as compared to those after LA, and the incidence of perioperative complications was lower.

scholarly journals Comparison of the clinical effect between the lower sternal incision and the left parasternal fourth intercostal incision in the transthoracic closure of ventricular septal defect

2020 ◽  
Author(s):  
Jun Ma ◽  
Wenlin Shangguan ◽  
Liang-wan Chen ◽  
Dong-Shan Liao
Keyword(s):  
Mechanical Ventilation ◽  
Ventricular Septal Defect ◽  
Clinical Effect ◽  
Septal Defect ◽  
Operation Time ◽  
Ventilation Time ◽  
Significant Difference ◽  
Group A ◽  
Mechanical Ventilation Time ◽  
Group B

Abstract Background: To analyze the clinical effect of two different ways of minimally invasive transthoracic closure in children with ventricular septal defect (VSD) Methods: From January 2015 to July 2019, 294 children with VSD were enrolled in the Fujian Medical University Union Hospital, who underwent VSD closure through the left sternal fourth intercostal incision (group A: n = 95) and the lower sternal incision (group B: n = 129) Results: The operation time, bleeding volume, postoperative mechanical ventilation time, postoperative ICU monitoring time, postoperative hospitalization time and complication rate in group A were significantly lower than those in group B (P < 0.05). There was no significant difference between the two groups in the operation success rate, mechanical ventilation time and total hospitalization cost (P > 0.05). Conclusion : The transthoracic closure of ventricular septal defect through the left sternal fourth intercostal incision is feasible, safe, cosmetic, and worth popularizing.

scholarly journals Comparative evaluation of the clinical effects of high Air-Through soft diaper and standard diaper in Indian babies with diaper rash

2021 ◽  
Vol 7 (4) ◽  
pp. 353-359
Author(s):  
Salvi Anjali N ◽  
Rajiv Joshi ◽  
Amit Bhawe ◽  
Rinko Takagi ◽  
Haruko Toyoshima ◽  
...  
Keyword(s):  
Clinical Effect ◽  
Clinical Effects ◽  
Diaper Dermatitis ◽  
Treatment Groups ◽  
Randomized Controlled ◽  
Change In The Mean ◽  
Group A ◽  
The Mean ◽  
The Difference ◽  
Group B

The incidence of diaper dermatitis (rash) in India is reported to be in the range of four to thirty-five per cent in children up to 2 years of age. To evaluate the clinical effect of using High Air-Through Soft Diaper and babies’ favourite diaper (Standard diaper) on Indian babies’ skin. This was a single-blinded, randomized, controlled, cross-over study. Eligible babies were randomized in two treatment groups. Babies in Group A used High Air-Through Soft Diaper for the first two weeks and then used standard diaper for the next 2 weeks. Babies in Group B used a standard diaper for the first two weeks and then used a High Air-Through Soft Diaper for the next 2 weeks. The study was completed with 105 babies. Theevaluation of the skin using the scoring system and photographs for representative purposes. At baseline, the mean total diaper rash scores were comparable in both Group A and Group B viz. 3.04 ± 1.00 and 3.30 ± 1.04 respectively and the difference was not statistically significant (p = 0.195). After 2 weeks, the mean total diaper rash score increased significantly from the baseline in both Group A and Group B (5.05 ± 1.97; p = 0.001 and 6.16 ± 2.22, p = 0.001 respectively); the rise in the mean total diaper rash score was significantly more in Group B than that in Group A (p = 0.045). After 4 weeks, a significant increase in the mean total diaper rash score (1.31 ± 2.69; p =0.001) was observed from what it was at 2 weeks in the Group A and there was an insignificant decrease in the mean total diaper rash score (-0.52 ± 2.54; p =0.153) in Group B from what it was at 2 weeks; the change in the mean total diaper rash score was significantly more in Group A than that in Group B (P = 0.001). Both High Air-Through Soft Diaper and standard diaper in babies caused a significant increase in mean total diaper rash score. However, the extent and the degree of rash induced with the use of High Air-Through Soft Diaper was significantly less than that during the usage of the standard diaper. Thus, High Air-Through Soft Diaper due to technologies used in it appears to be superior to the standard diaper in reducing the mean total diaper rash score.

The Accuracy of Patient Specific Three-Dimensional Digital Ostectomy Template for Mandibular Angle Ostectomy

2021 ◽  
Author(s):  
Guoping Wu ◽  
Zhiyang Xie ◽  
Wensong Sahngguan ◽  
Wenwen Zhang ◽  
Shu Wang ◽  
...  
Keyword(s):  
Operating Time ◽  
Three Dimensional ◽  
Patient Specific ◽  
Mandibular Angle ◽  
Significant Difference ◽  
Postoperative Drainage ◽  
Group A ◽  
The Mean ◽  
Group B ◽  
Mean Time

Abstract Background Despite the three-dimensional (3D)-printed digital ostectomy template (DOT) helps surgeons perform mandibular angle ostectomy (MAO) more precisely and safely, the clinical application of DOT is problematic. Objectives The aim of this study was to evaluate the accuracy of DOT and improve the precision of MAO. Methods A total of 20 patients with a prominent mandibular angle (PMA) were allocated into two groups with 10 patients in each group. The conventional digital ostectomy template (CDOT), and the novel digital ostectomy template (NDOT) were applied to guide MAO in group A and B, respectively. The mean time taken for curved osteotomy and the volume of postoperative drainage on one side within 24 hours were recorded. The deviations between the simulated and postoperative lower border of the mandible were measured on both sides. Results All the patients were satisfied with the cosmetic outcomes. Statistical results showed that the mean time taken for curved osteotomy in group B was shorter than that of group A, and the volume of postoperative drainage on one side within 24 hours was similar between the two groups. The deviations at the anterior and posterior parts of the inferior border showed the accuracy of osteotomy in group B was higher than that in group A, and there was no significant difference between the two groups in the middle part. Conclusions The NDOT is easy to be located and fixed tightly, which reduced the operating time and increased the safety and precision of the procedures.

scholarly journals Comparison of the clinical effect between the lower sternal incision and the left parasternal fourth intercostal incision in the transthoracic closure of ventricular septal defect

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Jun Ma ◽  
Wenlin Shangguan ◽  
Liang-Wan Chen ◽  
Dong-shan Liao
Keyword(s):  
Mechanical Ventilation ◽  
Ventricular Septal Defect ◽  
Clinical Effect ◽  
Septal Defect ◽  
Operation Time ◽  
Ventilation Time ◽  
Significant Difference ◽  
Group A ◽  
Mechanical Ventilation Time ◽  
Group B

Abstract Background To analyze the clinical effect of two different ways of minimally invasive transthoracic closure in children with ventricular septal defect (VSD). Methods From January 2015 to July 2019, 294 children with VSD were enrolled in the Fujian Medical University Union Hospital. Patients were divided into two groups – those who underwent VSD closure through the left sternal fourth intercostal incision (group A: n = 95) and the lower sternal incision (group B: n = 129). Results The operation time, bleeding volume, postoperative mechanical ventilation time, postoperative intensive care unit (ICU) monitoring time, postoperative hospitalization time and complication rate in group A were significantly lower than those in group B (P < 0.05). There was no significant difference between the two groups in the operation success rate, mechanical ventilation time and total hospitalization cost (P > 0.05). Conclusion The transthoracic closure of ventricular septal defect through the left sternal fourth intercostal incision is feasible, safe, cosmetic, and worth popularizing.

scholarly journals Effects of dorsal root ganglion destruction by adriamycin in patients with postherpetic neuralgia

2012 ◽  
Vol 27 (6) ◽  
pp. 404-409 ◽  
Author(s):  
He Chun-jing ◽  
Luo yi-ran ◽  
Nie hao-xiong
Keyword(s):  
Dorsal Root Ganglion ◽  
Postherpetic Neuralgia ◽  
Dorsal Root ◽  
Control Group ◽  
Clinical Effects ◽  
Long Term Effects ◽  
Significant Difference ◽  
Group A ◽  
Group B ◽  
Time Point

PURPOSE: To investigate the effects of dorsal root ganglion destruction in patients with postherpetic neuralgia (PHN). METHODS: Seventy-two patients with PHN selected were randomly divided into two groups (n=36). Group A was the control group (treated by injection) and group B was the group of dorsal root ganglion destruction by adriamycin. Visual analog scale scores (VAS), SAS, SF-MPQ scores. Clinical effects and therapy safety were evaluated before therapy, one week, three and six months after therapy. Forty-four patients were available for intention-to-treat analysis. RESULTS: The average pain scores on the Likert scale were significantly reduced at each point in group B. Patients in group B reported clinical effectiveness at six months as excellent response, good response, improved but unsatisfactory or unchanged 16, 12 and 8.VAS scores at each time point after the operation were lower than that before operation and in group A, there was significant difference. Patients showed significant improvement in sleep scores in group B. There was significant difference at T2 in group A than T1. There was no significant difference in group A at T3, T4 after the operation than that before operation. Between group comparison: there was significant difference between group A and group B at each time point after the operation. CONCLUSIONS: Dorsal root ganglion destruction by adriamycin under guidance of C-arm perspective, the puncture operation was accurate without any adverse reaction or serious complications, which could effectively relieve pain of patients with postherpetic neuralgia, but the long-term effects needed further study.

Clinical effect analysis of laminectomy alone and laminectomy with instrumentation in the treatment of TOLF: a multicentre retrospective study  

2021 ◽  
Author(s):  
Zhe Wei Wang ◽  
Zheng Wang ◽  
Yan Hong Zhou ◽  
Jia Yuan Sun ◽  
Wen Yuan Ding ◽  
...  
Keyword(s):  
Clinical Effect ◽  
Cross Sectional ◽  
Improvement Rate ◽  
Duration Of Symptoms ◽  
Residual Rate ◽  
Score Improvement ◽  
Signal Change ◽  
Significant Difference ◽  
Group A ◽  
Group B

Abstract Background To explore the clinical effect of laminectomy alone and laminectomy with instrumentation in the treatment of TOLF.Methods A retrospective study was conducted on the clinical data of 142 patients with TOLF and laminectomy in the Spine surgery of the XXX Medical University from January 2003 to January 2018. According to whether the laminectomy was combined with instrumentation, the patients were divided into two groups: group A (laminectomy alone LA, n = 77) and group B (laminectomy with instrumentation LI, n = 65). Comparison possible influencing factors of demographic variables and operation-related variables between the two groups. In this study, the clinical effects of laminectomy alone and laminectomy with instrumentation in the treatment of TOLF were discussed. Thus to explore the clinical effect of LA and LI in the treatment of TOLF.Results In terms of demographics, there was a statistically significant difference in BMI between group A and Group B (P < 0.05). The differences in Age, Sex, Smoking, Drinking, Heart disease, Hypertension and Diabetes were not statistically significant (P༞0.05). In terms of preoperative symptoms, there was significant difference in Gait disturbance, Pain in LE,Urination disorder between group A and group B (P < 0.05), but there was no significant difference in other variables between the two groups (P > 0.05). In terms of operation-related variables, there was significant difference in Preoperative duration of symptoms, Intramedullary signal change on MRI, Dural ossification, Residual rate of cross-sectional spinal canal area on CT, Shape on the sgittal MRI, Operation time, Pre-mJOA, Post-mJOA at 1 year,Leakage of cerebrospinal fluid between group A and group B (P < 0.05), but there was no significant difference in other variables between the two groups (P > 0.05). The preoperative average JOA score of group A was 6.37, and that of group B was 5.19. In group A, the average JOA score at 6 months, 1 year and 2 years after surgery was 7.87, 8.23 and 8.26, respectively, and the average JOA score improvement rate was 32.79%, 38.32% and 38.53%, respectively. In group B, the average JOA score at 6 months, 1 year and 2 years after surgery was 7.74, 8.15 and 8.29, respectively, and the average JOA score improvement rate was 39.15%, 46.86% and 47.12%, respectively.Conclusions Currently, there was no consensus on whether instrumentation is needed after laminectomy for TOLF. We found that for patients with long duration of Gait disturbance, Urination disorder, Preoperative duration of symptoms, Intramedullary signal change on MRI, Dural ossification, Residual rate of cross-sectional spinal canal area on CT less than 60%, Shape on the sgittal MRI as Beak and low Pre-mJOA had better clinical effect after LI than that LA, and the incidence of perioperative complications was lower.

scholarly journals Percutaneous Nephrolithotomy: A Comparison of Tubeless versus the Standard technique

2021 ◽  
Vol 25 (1) ◽  
pp. 140-144
Author(s):  
Zein El Amir ◽  
Muhammad Ali Shahiman ◽  
Zeeshan Qadeer ◽  
Rameez Ahmed Mughal ◽  
Ashfaq Ali
Keyword(s):  
Major Complication ◽  
Postoperative Outcome ◽  
Standard Technique ◽  
Significant Difference ◽  
Postoperative Drainage ◽  
Dj Stent ◽  
Group A ◽  
The Mean ◽  
Group B ◽  
Tubeless Pcnl

Objective: The proposed study aimed to assess the utility of tubeless PCNL in terms of efficacy and safety when compared with the standard tubed PCNL. Materials & Methods: In this study 280 patients (age ranged 08-70 years) who underwent PCNL were included. Results: The patients were from both genders i.e., 156 males and 124 females. Out of 280 patients, 140 had a 16 FR nephrostomy tube (Group A) whiles an equal number had 4.8F DJ Stent (Group B) for postoperative drainage. A comparison of the postoperative outcome among the two groups was made for a period of two years (November 2017 to October 2019). Neither any significant difference was found in the mean stone size, operative time, nor was stone-free status, nor any major complication observed. The mean hospital stay for group A and group B was 4.5 days (range 3 to 6) and 3.2 days (range 2 to 4) respectively. An early postoperative wound soakage was found in 18 (12.8%) cases of group A in contrast to the group B patients in whom only 2 (1.4%) had soakage. Conclusion: It was concluded that Tubeless PCNL as compared to the standard tubed PCNL was found more efficacious and safer and it should be adopted as a routine procedure.

DeVega versus ring annuloplasty in severe functional tricuspid insufficiency and their impact on the right ventricle

2019 ◽  
Vol 1 (4) ◽  
pp. 133-139
Author(s):  
Yasser Hamdy ◽  
Mohammed Mahmoud Mostafa ◽  
Ahmed Elminshawy
Keyword(s):  
Right Ventricular ◽  
Tricuspid Valve ◽  
Tricuspid Regurgitation ◽  
Early Postoperative Period ◽  
Tricuspid Valve Repair ◽  
Ring Annuloplasty ◽  
Significant Difference ◽  
Group A ◽  
Group B ◽  
The Right

Background: Functional tricuspid valve regurgitation secondary to left-sided valve disease is common. DeVega repair is simple, but residual regurgitation with subsequent impairment of the right ventricular function is a concern. This study aims to compare tricuspid valve repair using DeVega vs. ring annuloplasty and their impact on the right ventricle in the early postoperative period and after six months. Methods: This is a prospective cohort study of 51 patients with rheumatic heart disease who underwent tricuspid valve repair for secondary severe tricuspid regurgitation. Patients were divided into two groups: group A; DeVega repair (n=34) and group B; ring annuloplasty repair (n=17). Patients were assessed clinically and by echocardiography before discharge and after six months for the degree of tricuspid regurgitation, right ventricular diameter and tricuspid annular plane systolic excursion (TAPSE). Results: Preoperative echocardiographic assessment showed no difference in left ventricular end-systolic diameter, end-diastolic diameter, ejection fraction and right ventricular diameter, however; group A had significantly better preoperative right ventricular function measured by TAPSE (1.96 ± 0.27 vs1.75 ± 0.31 cm; p=0.02). Group B had significantly longer cardiopulmonary bypass time (127.65 ± 13.56 vs. 111.74 ± 18.74 minutes; p= 0.003) and ischemic time (99.06 ± 11.80 vs. 87.15 ± 16.01 minutes; p= 0.009). Pre-discharge, there was no statistically significant difference in the degree of tricuspid regurgitation, but the right ventricular diameter was significantly lower in group B (2.66 ± 0.41 and 2.40 ± 0.48 cm; p=0.049). After six months of follow up, the degree of tricuspid regurgitation (p= 0.029) and the right ventricular diameter were significantly lower in the ring annuloplasty group (2.56 ± 0.39 and 2.29 ± 0.44 cm; p=0.029). Although there was a statistically significant difference in preoperative TAPSE, this difference disappeared after six months. Conclusion: Both DeVega and ring annuloplasty techniques were effective in the early postoperative period, ring annuloplasty was associated with lesser residual regurgitation and better right ventricular remodeling in severe functional tricuspid regurgitation than DeVega procedure after 6-months of follow up.

Effect of short-term use of oral contraceptive pills on intraocular pressure

2020 ◽  
Vol 35 (3) ◽  
Author(s):  
Tayyaba Gul Malik ◽  
Hina Nadeem ◽  
Eiman Ayesha ◽  
Rabail Alam
Keyword(s):  
Oral Contraceptive ◽  
Childbearing Age ◽  
Short Term ◽  
Oral Contraceptive Pills ◽  
Contraceptive Pills ◽  
Time Period ◽  
Significant Difference ◽  
Group A ◽  
Group B ◽  
Short Time

Objective: To study the effect of short-term use of oral contraceptive pills on intra-ocular pressures of women of childbearing age.   Methods: It was a comparative observational study, conducted at Arif memorial teaching hospital and Allied hospital Faisalabad for a period of six months. Hundred female subjects were divided into two groups of 50 each. Group A, included females, who had been taking oral contraceptive pills (OCP) for more than 6 months and less than 36 months. Group B, included 50 age-matched controls, who had never used OCP. Ophthalmic and systemic history was taken. Careful Slit lamp examination was performed and intraocular pressures (IOP) were measured using Goldman Applanation tonometer. Fundus examination was done to rule out any posterior segment disease. After collection of data, we analyzed and compared the intra ocular pressures between the two groups by using ANOVA in SPSS version 21.   Results: Average duration of using OCP was 14.9 months. There was no significant difference of Cup to Disc ratios between the two groups (p= 0.109). However, significant difference was noted between the IOP of OCP group and controls. (p=0.000). Conclusion: OCP significantly increase IOP even when used for short time period.

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