SURGICAL TREATMENTS OF OBSTRUCTIVE SLEEP APNEA IN SEOUL NATIONAL UNIVERSITY OF DENTAL HOSPITAL

2018 ◽  
Vol 2 (1) ◽  
pp. 13-19
Author(s):  
Jin-Young CHOI ◽  
1990 ◽  
Vol 83 (6) ◽  
pp. 897-903
Author(s):  
Kiminori Sato ◽  
Takao Mitsumasu ◽  
Minoru Hirano ◽  
Tatayu Kotorii ◽  
Tetsuro Sakamoto ◽  
...  

SLEEP ◽  
2021 ◽  
Author(s):  
Kristján Godsk Rögnvaldsson ◽  
Elías Sæbjörn Eyþórsson ◽  
Össur Ingi Emilsson ◽  
Björg Eysteinsdóttir ◽  
Runólfur Pálsson ◽  
...  

Abstract Study Objectives Obstructive sleep apnea (OSA) has been proposed as a risk factor for severe COVID-19. Confounding is an important consideration as OSA is associated with several known risk factors for severe COVID-19. Our aim was to assess the association of OSA with hospitalization due to COVID-19 using a population-based cohort with detailed information on OSA and comorbidities. Methods Included were all community-dwelling Icelandic citizens 18 years of age and older diagnosed with SARS-CoV-2 infection in 2020. Data on demographics, comorbidities, and outcomes of COVID-19 was obtained from centralized national registries. Diagnosis of OSA was retrieved from the centralized Sleep Department Registry at Landspitali–The National University Hospital. Severe COVID-19 was defined as the composite outcome of hospitalization and death. The associations between OSA and the outcome were expressed as odds ratios (OR) with 95% confidence intervals (95% CI), calculated using logistic regression models and inverse probability weighting. Results A total of 4,756 individuals diagnosed with SARS-CoV-2 infection in Iceland were included in the study (1.3% of the Icelandic population), of whom 185 had a diagnosis of OSA. In total, 238 were hospitalized or died, 38 of whom had OSA. Adjusted for age, sex, and BMI, OSA was associated with poor outcome (OR 2.2, 95% CI 1.4 -3.5). This association was slightly attenuated (OR 2.0, 95% CI 2.0, 1.2-3.2) when adjusted for demographic characteristics and various comorbidities. Conclusions OSA was associated with twofold increase in risk of severe COVID-19, and the association was not explained by obesity or other comorbidities.


2021 ◽  
Author(s):  
Wei Yang Lim ◽  
Kay Choong See

Abstract Background and Objective Obstructive sleep apnea (OSA) is a highly prevalent condition worldwide. Untreated, it is associated with multiple medical complications as well as a reduced quality of life. Home sleep apnea tests are increasingly used for its diagnosis and evaluation of severity, but using total bed time rather than total sleep time may underestimate OSA severity. We aim to uncover the extent and predictors of OSA misclassification when using total bed time. Methods A retrospective observational study was conducted using data from the sleep laboratory of the National University Hospital, Singapore, a tertiary hospital with 1200 beds. Misclassification of OSA was defined as any OSA severity that was less severe using total bed time versus total sleep time. Logistic regression was used to identify predictors of OSA misclassification.Results A total of 1621 patients were studied (mean age 45.6 + 15.9 years; 73.4% male). 300 (18.5%) patients were misclassified. Risk factors for OSA misclassification included age (OR 1.02, 95% CI 1.01-1.03, P=0.001) and body-mass index (BMI) (OR 0.97,95% CI 0.95-0.99, P=0.015). Risk for misclassification was significant in patients aged>57 years old, with BMI<32.3 kg/m2. Conclusion Using total bed time rather than total sleep time to quantify OSA severity was associated with a significant risk of misclassification, particularly in patients aged >57 years old, with BMI <32.3 kg/m2. This was a novel finding that has not been previously reported.


Author(s):  
Kevin Motz ◽  
Susheel P. Patil

Obstructive sleep apnea (OSA) is characterized by repeated collapse of the upper airway during sleep that leads to reduced airflow and oxyhemoglobin desaturation. The disorder is highly prevalent, with obesity, male sex, and increasing age as risk factors. Consequences of untreated OSA include neurocognitive impairment, such as excessive daytime sleepiness, and an increased risk of cardiovascular and cerebrovascular disease. Positive airway pressure therapy remains the most common treatment for OSA. Over the last few decades, alternative nonsurgical and surgical treatments have been developed. Although surgical approaches are rarely curative, careful patient selection may benefit a subpopulation of people living with OSA. Selective hypoglossal nerve stimulation represents a new treatment strategy for the management of OSA in selected patients.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Wei Yang Lim ◽  
Kay Choong See

AbstractObstructive sleep apnea (OSA) is a highly prevalent condition worldwide. Untreated, it is associated with multiple medical complications as well as a reduced quality of life. Home sleep apnea tests are increasingly used for its diagnosis and evaluation of severity, but using total bed time rather than total sleep time may underestimate OSA severity. We aim to uncover the extent and predictors of OSA misclassification when using total bed time. A retrospective observational study was conducted using data from the sleep laboratory of the National University Hospital, Singapore, a tertiary hospital with 1200 beds. Misclassification of OSA was defined as any OSA severity that was less severe using total bed time versus total sleep time. Logistic regression was used to identify predictors of OSA misclassification. A total of 1621 patients were studied (mean age 45.6 ± 15.9 years; 73.4% male). 300 (18.5%) patients were misclassified. Risk factors for OSA misclassification included age (OR 1.02, 95% CI 1.01–1.03, P = 0.001) and body-mass index (BMI) (OR 0.97, 95% CI 0.95–0.99, P = 0.015). Risk for misclassification was significant in patients aged ≥ 57 years old, with BMI < 32.3 kg/m2. Using total bed time rather than total sleep time to quantify OSA severity was associated with a significant risk of misclassification, particularly in patients aged ≥ 57 years old, with BMI < 32.3 kg/m2.


2019 ◽  
Vol 4 (5) ◽  
pp. 878-892
Author(s):  
Joseph A. Napoli ◽  
Linda D. Vallino

Purpose The 2 most commonly used operations to treat velopharyngeal inadequacy (VPI) are superiorly based pharyngeal flap and sphincter pharyngoplasty, both of which may result in hyponasal speech and airway obstruction. The purpose of this article is to (a) describe the bilateral buccal flap revision palatoplasty (BBFRP) as an alternative technique to manage VPI while minimizing these risks and (b) conduct a systematic review of the evidence of BBFRP on speech and other clinical outcomes. A report comparing the speech of a child with hypernasality before and after BBFRP is presented. Method A review of databases was conducted for studies of buccal flaps to treat VPI. Using the principles of a systematic review, the articles were read, and data were abstracted for study characteristics that were developed a priori. With respect to the case report, speech and instrumental data from a child with repaired cleft lip and palate and hypernasal speech were collected and analyzed before and after surgery. Results Eight articles were included in the analysis. The results were positive, and the evidence is in favor of BBFRP in improving velopharyngeal function, while minimizing the risk of hyponasal speech and obstructive sleep apnea. Before surgery, the child's speech was characterized by moderate hypernasality, and after surgery, it was judged to be within normal limits. Conclusion Based on clinical experience and results from the systematic review, there is sufficient evidence that the buccal flap is effective in improving resonance and minimizing obstructive sleep apnea. We recommend BBFRP as another approach in selected patients to manage VPI. Supplemental Material https://doi.org/10.23641/asha.9919352


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