scholarly journals Genetic ancestry and social race are nearly interchangeable

OpenPsych ◽  
2021 ◽  
Author(s):  
Emil O. W. Kirkegaard
Keyword(s):  
Genetic Ancestry ◽  
Social Race

scholarly journals Genetic ancestry inferred from autosomal and Y chromosome markers and HLA genotypes in Type 1 Diabetes from an admixed Brazilian population

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Rossana Santiago de Sousa Azulay ◽  
Luís Cristóvão Porto ◽  
Dayse Aparecida Silva ◽  
Maria da Glória Tavares ◽  
Roberta Maria Duailibe Ferreira Reis ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Native American ◽  
Y Chromosome ◽  
Chromosome Analysis ◽  
Brazilian Population ◽  
Genetic Ancestry ◽  
Sample Sizes ◽  
Chromosome Markers ◽  
Hla Genotypes

AbstractThis study aimed to investigate the relationship between genetic ancestry inferred from autosomal and Y chromosome markers and HLA genotypes in patients with Type 1 Diabetes from an admixed Brazilian population. Inference of autosomal ancestry; HLA-DRB1, -DQA1 and -DQB1 typifications; and Y chromosome analysis were performed. European autosomal ancestry was about 50%, followed by approximately 25% of African and Native American. The European Y chromosome was predominant. The HLA-DRB1*03 and DRB1*04 alleles presented risk association with T1D. When the Y chromosome was European, DRB1*03 and DRB1*04 homozygote and DRB1*03/DRB1*04 heterozygote genotypes were the most frequent. The results suggest that individuals from Maranhão have a European origin as their major component; and are patrilineal with greater frequency from the R1b haplogroup. The predominance of the HLA-DRB1*03 and DRB1*04 alleles conferring greater risk in our population and being more frequently related to the ancestry of the European Y chromosome suggests that in our population, the risk of T1D can be transmitted by European ancestors of our process miscegenation. However, the Y sample sizes of Africans and Native Americans were small, and further research should be conducted with large mixed sample sizes to clarify this possible association.

Effects of Receiving Genetic Ancestry Results on Emerging Adults’ Ethnic-Racial Identity Affirmation

2021 ◽  
pp. 216769682110208
Author(s):  
Chelsea D. Williams ◽  
Tricia Smith ◽  
Amy Adkins ◽  
Chloe J. Walker ◽  
Arlenis Santana ◽  
...  
Keyword(s):  
Racial Identity ◽  
Emerging Adults ◽  
Genetic Ancestry ◽  
Male Students ◽  
Race And Gender ◽  
White Males ◽  
Post Test ◽  
And Gender ◽  
Testing Condition ◽  
And Control

Ethnic-racial identity (ERI) is associated with adaptive outcomes in emerging adulthood, but more research is needed on factors that may inform ERI, such as receiving one’s genetic ancestry results. The current study examined changes in ERI using a pre-test post-test design in which 116 emerging adults 18–25 years were randomly assigned to either receiving their genetic ancestry results before the post-test (the testing condition) or after post-test (the control condition). We also tested whether ethnicity/race and gender moderated these associations. Findings indicated that male students of color (SOC) in the testing condition experienced an increase in ERI affirmation from pre-test to post-test, and male SOC in the control condition experienced a decrease in ERI affirmation from pre-test to post-test. There were no significant differences in ERI affirmation change between students in the testing condition and control condition for female SOC, White males, or White females.

Is genetic ancestry a tool to combat health disparities?

Cell ◽  
2021 ◽  
Vol 184 (8) ◽  
pp. 1964-1965
Author(s):  
Rex L. Chisholm
Keyword(s):  
Health Disparities ◽  
Genetic Ancestry
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