scholarly journals Results of surgical treatment of patients, suffering hepatic cirrhosis and cholestatic syndrome

2018 ◽  
Vol 85 (7) ◽  
pp. 24-26
Author(s):  
О. F. Dzygal ◽  
І. М. Deykalo

Objective. Determination of the surgical treatment efficacy in patients, suffering hepatic cirrhosis (HC), in presence of cholestatic syndrome (CHS). Маterials and methods. Results of surgical treatment of 1117 patients, suffering HC with suspicion on biliary calculous disease and obturation jaundice, in 52 of whom choledocholithiasis was diagnosed, were analyzed retrospectively. Results. Of 52 patients, suffering HC and CHS due to choledocholithiasis, in 43 a one-stage surgical tactics was used, and in 9 – a two-staged one. Of 43 patients, complicated by choledocholithiasis, in whom a one-stage surgical tactics of treatment was applied, 27 were operated using open access and16 - laparoscopically. Choledocholithiasis was eliminated in 12 of 16 patients laparoscopically, and in 4 patients a conversion was performed. Conclusion. Оne-stage tactics of surgical treatment in patients, suffering HC and CHS, is considered effective due to possibility to perform a majority of operative interventions laparoscopically with minimal rate of complications and lethality.

2021 ◽  
Vol 179 (5) ◽  
pp. 75-80
Author(s):  
A. A. Pechetov ◽  
B. G. Alekyan ◽  
A. N. Lednev ◽  
M. A. Makov ◽  
N. G. Karapetyan ◽  
...  

Surgical treatment of oncological diseases with concomitant somatic pathologies is a complex issue. In situations when concomitant somatic pathology also requires a surgical approach, the determination of adequate treatment tactics is most relevant. Delayed surgical treatment of cancer increases the risks of progression and generalization of the process; surgical treatment of a tumor against the background of decompensated concomitant pathology potentially entails risks of an unfavorable outcome. With a combination of oncological and somatic diseases, the definition of treatment algorithms today is one of the primary tasks.This paper presents a clinical observation of one-stage surgical treatment of lung cancer and severe aortic stenosis, provides a brief literature review on this topic. 


2018 ◽  
Vol 85 (4) ◽  
pp. 35-37
Author(s):  
О. D. Nikitin

Objective. Determination of efficacy of intracytoplasmatic introduction of spermatozoid (ICSI) in treatment of infertile men, suffering hypergonadotropic hypogonadism, complicated by nonobstructive azoospermia (NОА), using technologies of TESE (еxtraction of spermatozoids), TESA (transcutaneous аspiration of sperm from testicle), аnd their combination (TESE and TESA) as well for the sperm cells extraction. Маterials and methods. The patients were divided into three Groups: Group 1 (TESE) – 31 patients, in whom the TESE procedure was applied for the sperm cells extraction from testicles; Group 2 (TESА) – 33 patients, in whom the TESА procedure was used for the sperm cells extraction; Group 3 (TESE and TESА) – 35 patients, in whom the combined TESА and TESE procedure was used for the sperm cells extraction. General duration of observation for the patients’ treatment efficacy in this Group have constituted 2 years. Results. The sperm cells extraction in accordance to the TESE procedure have secured successful extraction of spermatozoids in 8 (25.8%) of 31 patients Group 1. After the ICSI procedure application in 16.1% wives of these patients the fertilization have succeeded, got pregnant 12.9%, and gave birth 9.7%. The sperm cells extraction in accordance to the TESA procedure have secured successful extraction of sperm cells in 12 (36.4%) of 33 patients Group 2. After application of the ICSI procedure in 24.2% wives of these patients the fertilization have succeeded, have got pregnant 18.2%, and gave birth – 12.1%. The sperm cells extraction in accordance to the joint TESE and TESА procedure have secured successful extraction of spermatozoids in 16 (45.7%) of 35 patients Group 3. After application of the ICSI procedure in 34.3% wives of these patients the patients’ fertilization have succeeded, have got pregnant 28.5%, and gave birth – 20.0%. Conclusion. The combined procedure (TESE and TESA) proposed for infertile men with NОА, caused by hypergonadotropic hypogonadism, succeeds more often, and after this the indices of the ovum successful fertilization and the birthrate are higher, comparing with that after TESE or TESA procedures.


2018 ◽  
Vol 85 (6) ◽  
pp. 24-26
Author(s):  
О. F. Dzygal ◽  
І. М. Deykalo

Objective. Determination of efficacy of miniinvasive surgical treatment of portal hypertension (PG) in patients, suffering hepatic cirrhosis (HC) in immediate and late postoperative periods. Маterials and methods. Results of surgical treatment of 200 patients, suffering HC, were analyzed retrospectively: in 102 of them (Group I) HC and gastro-esophageal varices were diagnosed, in 98 (Group II) - HC with PG. Results. There was established, that miniinvasive surgical treatment in volume of the gastric veins embolization, аs well as operations of selective and partial portocaval shunting with the objective to correct a portal hypertension in patients, suffering HC, constitutes effective alternative method of surgical treatment. Conclusion. The decompression operations for portal system in patients with HC prevent the esophago-gastric hemorrhage occurrence in late period of follow-up and guarantee good survival of the patients, suffering compensated and subcompensated hepatic function.


2019 ◽  
Vol 42 (3) ◽  
pp. 46-49
Author(s):  
Vovk V. A.

Purpose of the study. Improvement of acute cholangitis treatment by improving surgical tactics, depending on the mechanisms of acute cholangitis development. Materials and methods. Analysis of 135 patients with gallstone origin acute cholangitis. In 18 (13,3%) of these patients, acute cholangitis was accompanied by acute destructive cholecystitis; in 7 (5,2%) cholangitis was complicated by liver abscesses formation. Endoscopic transpapillary intervention was performed on 132 (97,8%) patients, and laparoscopic operations – 105 (7,8%). Totally, among 135 patients were 248 stages of surgical treatment. One-stage treatment for cholangitis was performed in 33 patients, 2 stage – 91 patients, and three stages – 11 patients. Results. Complications after endoscopic and laparoscopic interferences occurred in 17 (12,6%) patients. Complications after endoscopic interventions were bleeding from papilla – 4, acute pancreatitis – 3; after laparoscopic interventions – inflammatory complications of postoperative wounds – 6, conversion – 5. Died 2 (1,5%) patients, the cause of death in both cases was sepsis. Conclusion. The ascending and bladder mechanisms of acute cholangitis development with cholelithiasis require a different sequence of stages of endoscopic transpapillary and laparoscopic surgical interventions. Differentiated tactics, depending on the cause of acute cholangitis, contribute to reducing the trauma of surgical treatment and improving its results. Keywords: acute cholangitis, cholelithiasis, mechanical jaundice, laparoscopy, endoscopy.


2020 ◽  
Vol 87 (5-6) ◽  
pp. 41-45
Author(s):  
Ya. P. Truba ◽  
M. P. Radchenko ◽  
I. V. Dzyurii ◽  
O. S. Golovenko ◽  
V. V. Lazoryshynets

Objective. To analyze immediate and late results of a one-stage surgical treatment of the main arteries transposition in conjunction with obstruction on the level of aortal arch. Materials and metods. For the period 2010 - 2019 yrs in Amosov National Institute of Cardiovascular Surgery and Scientific-Practical Medical Centre of Pediatric Cardiology and Cardio-Surgery in 52 newborn babies a one-stage correction of the main arteries transposition with obstruction on the level of aortal arch was conducted. In the investigation were included only the patients with a two-ventricle physiology and further two-ventricle correction. There were 35 (67.3%) boys and 17 (32.7%) girls. Average age of the patients was (0.6 ± 0.3) mo, average body mass - (3.6 ± 0.8) kg. The main method of diagnosis in determination of the failure and estimation of immediate and late results was echocardiographic examination. In 24 (46.2%) of the patients while doing reconstruction of the aortal arch a selective antegrade cerebral perfusion was conducted. Results. Hospital mortality have constituted 3.8% (n=2). Duration of artificial blood circulation have constituted (194.3 ± 73.1) min, aortal clamping - (108.5 ± 35.6) min, selective cerebral perfusion - (19.6 ± 7.2) min. In early postoperative period 6 (11.5%) patients have been with desintegrated sternum. Average duration of observation have constituted (3.7 ± 2.8) yr (from 1 no to 9.yrs). In late period one child died. In 5 (9.6%) patients in postoperative period restenosis in aortal arch have developed, who was successfully curated endovascularly, using balloon dilatation in 3 patients, In two secondary plasty of aortal arch was done surgically. Tracheal or the main bronchi compression, neurologic complications were not observed in remote period. Conclusion. One-stage correction of the main arteries transposition together with the aortal arch hypoplasia - an effective and secure method of treatment of a newborn children with good immediate and late results. The investigation conducted gives a background to conclude, that this surgical strategy constitutes the affordable alternative to two-staged surgical treatment of this complex pathology.


1984 ◽  
Vol 23 (06) ◽  
pp. 277-282 ◽  
Author(s):  
A. Van Lingen ◽  
G. Westera ◽  
M. van ◽  
W. Den Hollander ◽  
E. E. Van der Wall ◽  
...  

SummaryThis paper presents an alternative method of demarcating regions of in terest over the myocardium after ad ministration of 123I-heptadecanoic acid to patients with coronary artery disea se. In a matrix of 32 × 32 pixels the elimination rates of the radioactivity, which are not corrected for back ground activity, are visualized per pixel in a functional image. The func tional image showed areas in the myocardium with high values of uncorrected elimination rates. These areas corresponded with the tracer defects on the scintigram. Corrected elimination rates obtained from re gions of interest of functional images were comparable with those of scinti grams. Thus based on functional im ages of uncorrected elimination rates a reliable, objective determination of regions of interest over normal and abnormal myocardium can be made.


1967 ◽  
Vol 18 (01/02) ◽  
pp. 198-210 ◽  
Author(s):  
Ronald S Reno ◽  
Walter H Seegers

SummaryA two-stage assay procedure was developed for the determination of the autoprothrombin C titre which can be developed from prothrombin or autoprothrombin III containing solutions. The proenzyme is activated by Russell’s viper venom and the autoprothrombin C activity that appears is measured by its ability to shorten the partial thromboplastin time of bovine plasma.Using the assay, the autoprothrombin C titre was determined in the plasma of several species, as well as the percentage of it remaining in the serum from blood clotted in glass test tubes. Much autoprothrombin III remains in human serum. With sufficient thromboplastin it was completely utilized. Plasma from selected patients with coagulation disorders was assayed and only Stuart plasma was abnormal. In so-called factor VII, IX, and P.T.A. deficiency the autoprothrombin C titre and thrombin titre that could be developed was normal. In one case (prethrombin irregularity) practically no thrombin titre developed but the amount of autoprothrombin C which generated was in the normal range.Dogs were treated with Dicumarol and the autoprothrombin C titre that could be developed from their plasmas decreased until only traces could be detected. This coincided with a lowering of the thrombin titre that could be developed and a prolongation of the one-stage prothrombin time. While the Dicumarol was acting, the dogs were given an infusion of purified bovine prothrombin and the levels of autoprothrombin C, thrombin and one-stage prothrombin time were followed for several hours. The tests became normal immediately after the infusion and then went back to preinfusion levels over a period of 24 hrs.In other dogs the effect of Dicumarol was reversed by giving vitamin K1 intravenously. The effect of the vitamin was noticed as early as 20 min after administration.In response to vitamin K the most pronounced increase was with that portion of the prothrombin molecule which yields thrombin. The proportion of that protein with respect to the precursor of autoprothrombin C increased during the first hour and then started to go down and after 3 hrs was equal to the proportion normally found in plasma.


Author(s):  
Marcus D. Benedetto ◽  
Donald E. Antonson ◽  
Lawrence M. Elson ◽  
Londa D. Reid-Sanders ◽  
Jacquelyn I. Williams

2017 ◽  
Vol 63 (3) ◽  
pp. 470-474
Author(s):  
Rustem Topuzov ◽  
Georgiy Manikhas ◽  
Eskender Topuzov ◽  
Mikhail Khanevich ◽  
Magomed Abdulaev ◽  
...  

There are presented results of surgical treatment of 347 patients with colorectal cancer. Based on the retrospective analysis a comparative study of results of surgical treatment for colorectal cancer using laparoscopic technologies and “open” access was carried out. Predictive factors that correlate with the risk of postoperative complications with laparoscopic and “open” access at the surgical stage of treatment for colorectal cancer were determined.


2010 ◽  
Vol 68 (1) ◽  
pp. 130-143 ◽  
Author(s):  
Philip J. Bacon ◽  
William S. C. Gurney ◽  
Eddie McKenzie ◽  
Bryce Whyte ◽  
Ronald Campbell ◽  
...  

Abstract Bacon, P. J., Gurney, W. S. C., McKenzie, E., Whyte, B., Campbell, R., Laughton, R., Smith, G., and MacLean, J. 2011. Objective determination of the sea age of Atlantic salmon from the sizes and dates of capture of individual fish. – ICES Journal of Marine Science, 68: 130–143. The sea ages of Atlantic salmon indicate crucial differences between oceanic feeding zones that have important implications for conservation and management. Historical fishery-catch records go back more than 100 years, but the reliability with which they discriminate between sea-age classes is uncertain. Research data from some 188 000 scale-aged Scottish salmon that included size (length, weight) and seasonal date of capture on return to the coast were investigated to devise a means of assigning sea age to individual fish objectively. Two simple bivariate probability distributions are described that discriminate between 1SW and 2SW fish with 97% reliability, and between 2SW and 3SW fish with 70% confidence. The same two probability distributions achieve this accuracy across five major east coast Scottish rivers and five decades. They also achieve the same exactitude for a smaller recent dataset from the Scottish west coast, from the River Tweed a century ago (1894/1895), and for salmon caught by rod near the estuary. More surprisingly, they also achieve the same success for rod-caught salmon taken at beats remote from the estuary and including capture dates when some fish could have been in the river for a few months. The implications of these findings for fishery management and conservation are discussed.


Sign in / Sign up

Export Citation Format

Share Document