THE PROBLEM OF OSTEOPOROSIS IN MENOPAUSAL WOMEN AND POSSIBLE SOLUTIONS

2021 ◽  
Vol 2 (1) ◽  
pp. 15-17
Author(s):  
Maiorova M.O.

41 women with osteoporosis were examined. The age of the examined people ranged from 50 to 60 years. All the women were postmenopausal. As a result of the study, it was found that the most effective management strategy for such patients is a combination of menopausal hormone therapy and non-hormonal drugs that affect calcium metabolism in bone tissue, improve its metabolism and reduce resorption. If there are contraindications to MGT, prevention and treatment of osteoporosis should also be carried out using the appointment of non-hormonal drugs. In this case, the use of ipriflavone is effective.

ASJ. ◽  
2021 ◽  
Vol 1 (56) ◽  
pp. 28-33
Author(s):  
O. Kalinkina ◽  
Yu. Tezikov ◽  
I. Lipatov

87 patients aged 40-69 years in the period of pre- and postmenopause were examined. In the analysis of age-related dynamics of bone mineral density (BMD) It was found that densitometry indicators corresponding to osteoporosis directly correlate with age and duration of the postmenopausal period. It is advisable in women of this age group with a decrease in bone mineral density, the combined appointment of menopausal hormone therapy (MGT) and non-hormonal therapy affecting bone metabolism (calcitonin). For the purpose of MGT in premenopausal women, the use of femostone 2/10 is effective, in postmenopausal women - femostone 1/10 and femostone 1/5, which does not cause withdrawal bleeding. If there are contraindications to menopausal hormone therapy, the prevention and treatment of osteoporosis should be guided by the appointment of nonhormonal drugs, in particular, calcitonin.


2012 ◽  
Vol 1 (4) ◽  
pp. 106 ◽  
Author(s):  
Marco Giammanco ◽  
Danila Di Majo ◽  
Gaetano Leto ◽  
Carla Flandina ◽  
Melania Di Piazza ◽  
...  

Vitamin K is an essential fat soluble vitamin involved in the regulation of normal coagulation. However, growing evidence highlights that this molecule appears to be also implicated in the regulation of other important biological functions such as bone mineralization, calcium homeostasis, apoptosis, cell growth and signal transduction. In particular, many studies have focused their attention on the protective effects of vitamin K on bone tissue in the outlook of its use in the prevention and treatment of osteoporosis in post-menopausal women. The objective of the present paper is to review data of the literature regarding the metabolic effects of Vitamin K in bone tissue and its clinical role in the prevention and treatment of osteoporosis.


2000 ◽  
Author(s):  
A Cranney ◽  
V Robinson ◽  
G Guyatt ◽  
N Krolicki ◽  
JD Adachi ◽  
...  

Author(s):  
D. V. Lopatik ◽  
U. D. Kovalenko ◽  
Z. I. Kuvaeva ◽  
E. A. Manchik

Results of the study of the drug from calcium salts of amino acids (calcium diglycinate, calcium di-L-prolinate) on the model of osteoporosis in animals are described. The test substance was found to have better therapeutic effect in the regeneration of bone tissue in comparison with the drug containing calcium carbonate. The drug containing calcium salts of glycine and L-proline can be used for prevention and treatment of osteoporosis.


2018 ◽  
Vol 12_2018 ◽  
pp. 157-162 ◽  
Author(s):  
Gasparyan S.A. Gasparyan ◽  
Drosova L.D. Drosova ◽  
Karpov S.M. Karpov ◽  
Khripunova A.A. Khripunova ◽  

PLoS ONE ◽  
2013 ◽  
Vol 8 (11) ◽  
pp. e78016 ◽  
Author(s):  
Emilie Cordina-Duverger ◽  
Thérèse Truong ◽  
Antoinette Anger ◽  
Marie Sanchez ◽  
Patrick Arveux ◽  
...  

2013 ◽  
Vol 19 (3) ◽  
pp. 123 ◽  
Author(s):  
IK Jin Chang ◽  
Gi Youn Hong ◽  
Young Lim Oh ◽  
Byoung Ryun Kim ◽  
Seong Nam Park ◽  
...  

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