scholarly journals Selenium Status in Heifers, Late Pregnancy Cows and Their Calves in the Šumava Region, Czech Republic

2007 ◽  
Vol 76 (4) ◽  
pp. 519-524 ◽  
Author(s):  
P. Slavík ◽  
J. Illek ◽  
T. Zelený
Keyword(s):  
Selenium Concentration ◽  
Late Pregnancy ◽  
Serum Selenium ◽  
Selenium Status ◽  
Significant Difference ◽  
Serum Selenium Concentration ◽  
Production Stages ◽  
Mineral Licks ◽  
Gshpx Activity ◽  
The Difference

The objective of this study was to ascertain selenium status in beef cattle in different stages of production in the Šumava region. In the region, blood collections and analyses for selected metabolic variables were performed in 54 animals in different production stages (18 heifers, 18 cows in late pregnancy and 18 calves aged 3 weeks on the average). Three herds were studied. The selenium status was determined both directly by measuring serum selenium (Se) contents and indirectly by measuring glutathione peroxidase (GSH-Px) activity in whole blood. The mean serum selenium concentration in all the animals under study (n = 54) was 30.6 μg/l +/- 2.91, and mean GSH-Px activity was 167.01 μkat/l +/- 92.39. In heifers, mean serum selenium concentration was 34.81 μg/l +/- 13.84; mean GSHPx activity was 186.96 μkat/l +/- 112.15. In late pregnancy cows, mean serum selenium concentration was 26.58 μg/l +/- 8.01, mean GSH-Px activity was 94.55 +/- 35.72 μkat/l. In calves, mean serum selenium concentration and GSH-Px activity were 30.41 μg/l +/- 12 and 219.54 μkat/l +/- 64.41, respectively. There was a statistically significant difference between the heifers and late pregnancy cows in both variables under study. However, between the late pregnancy cows and the calves, only the difference in GSH-Px activity was significant. The results indicate severe Se deficiency in the animals under study. It means apart from other things that mineral licks used did not provide enough minerals to meet the basic requirements of the animals.

Serum selenium concentration and glutathione peroxidase activity and selenium content in testes of Polish Konik horses from selenium- -deficient area in North-Western Poland

2014 ◽  
Vol 17 (1) ◽  
pp. 165-167 ◽  
Author(s):  
B. Pilarczyk ◽  
A. Tomza-Marciniak ◽  
T. Stankiewicz ◽  
B. Błaszczyk ◽  
D. Gączarzewicz ◽  
...  
Keyword(s):  
Glutathione Peroxidase ◽  
Selenium Concentration ◽  
Serum Selenium ◽  
Optimal Range ◽  
Horse Breed ◽  
Serum Selenium Concentration ◽  
Nature Park ◽  
Gshpx Activity ◽  
Deficient Area ◽  
North Western

Abstract The aim of this study was to determine serum selenium concentrations in Polish Konik horses residing in the Odra Delta Nature Park (Poland) and to evaluate the activity of glutathione peroxidase and Se content in testes of this horse breed. In over 95% of cases, serum Se concentration was below the optimal range, and none of the horses examined was deficient in this trace element. The lack of Se deficiency in the animals examined suggests however, that the Polish Konik horses have a natural ability to the optimal use of nutrients available in their life area. Testicular content of Se and GSHPx activity in the colts was higher than those found in stallions, and a positive relationship between these antioxidants was demonstrated. The differences in Se contents and GSHPx activities in testes between colts and stallions suggest that selenoenzymes play important roles during the puberty of male horses.

Selenium status, thyroid volume, and multiple nodule formation in an area with mild iodine deficiency

2011 ◽  
Vol 164 (4) ◽  
pp. 585-590 ◽  
Author(s):  
Lone Banke Rasmussen ◽  
Lutz Schomburg ◽  
Josef Köhrle ◽  
Inge Bülow Pedersen ◽  
Birgit Hollenbach ◽  
...  
Keyword(s):  
Thyroid Gland ◽  
Iodine Deficiency ◽  
Regression Models ◽  
Thyroid Volume ◽  
Selenium Concentration ◽  
Serum Selenium ◽  
Selenium Status ◽  
Cross Sectional ◽  
Serum Selenium Concentration ◽  
Low Serum

ObjectiveThe objective was to study the associations between serum selenium concentration and thyroid volume, as well as the association between serum selenium concentration and risk for an enlarged thyroid gland in an area with mild iodine deficiency before and after iodine fortification was introduced. Another objective was to examine the association between serum selenium concentration and prevalence of thyroid nodules.DesignCross-sectional study.MethodsWe studied participants of two similar cross-sectional studies carried out before (1997–1998, n=405) and after (2004–2005, n=400) introduction of iodine fortification. Serum selenium concentration and urinary iodine were measured, and the thyroid gland was examined by ultrasonography in the same subjects. Associations between serum selenium concentration and thyroid parameters were examined in multiple linear regression models or logistic regression models.ResultsSerum selenium concentration was found to be significantly, negatively associated with thyroid volume (P=0.006), and a low selenium status significantly increased the risk for thyroid enlargement (P=0.007). Furthermore, low serum selenium status had a tendency to increase the risk for development of multiple nodules (P=0.087).ConclusionsLow serum selenium concentration was associated with a larger thyroid volume and a higher prevalence of thyroid enlargement.

Low Platelet Glutathione Peroxidase Activity and Serum Selenium Concentration in Patients with Chronic Renal Failure: Relations to Dialysis Treatments, Diet and Cardiovascular Complications

1993 ◽  
Vol 84 (6) ◽  
pp. 611-617 ◽  
Author(s):  
Domenico Girelli ◽  
Oliviero Olivieri ◽  
Anna Maria Stanzial ◽  
Margherita Azzini ◽  
Antonio Lupo ◽  
...  
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Glutathione Peroxidase ◽  
Peroxidase Activity ◽  
Selenium Concentration ◽  
Cardiovascular Complications ◽  
Serum Selenium ◽  
Selenium Status ◽  
Glutathione Peroxidase Activity ◽  
Serum Selenium Concentration

1. Selenium status was investigated in patients with chronic renal failure, with special regard to its relations to the dialysis treatments, dietary habits and clinical signs of atherosclerosis. 2. Serum selenium concentration and platelet glutathione peroxidase activity were measured in 45 patients with chronic renal failure subdivided into three groups according to the type of treatment: 15 non-dialysed, 15 on haemodialysis, 15 on continuous ambulatory peritoneal dialysis. A 7-day diet history was carried out in all patients. Seventeen of the patients with chronic renal failure had clinically overt cardiovascular disease. Forty-five age-matched healthy subjects were considered as controls. 3. Both serum selenium concentration and platelet glutathione peroxidase were significantly reduced in all patients with chronic renal failure compared with control subjects; a direct and significant correlation was found between the two parameters. No differences in selenium status were observed among the non-dialysed, haemodialysis and continuous ambulatory peritoneal dialysis groups. No correlation between total calorie or protein intakes and selenium indices were observed. The chronic renal failure patients with cardiovascular complications showed a further significant reduction in both serum selenium concentration and platelet glutathione peroxidase activity as compared with the patients without cardiovascular complications; these two groups were similar with respect to the other well-known cardiovascular risk factors (age, smoking, plasma lipids, hypertension, body mass index). 4. It is concluded that a low selenium concentration is present in chronic renal failure, which is independent of dialysis and is accompanied by biological repercussion in terms of reduced platelet glutathione peroxidase activity. It may represent a previously unrecognized cofactor favouring the ‘accelerated’ atherosclerosis of patients with chronic renal failure.

scholarly journals Biofortified Maize Improves Selenium Status of Women and Children in a Rural Community in Malawi: Results of the Addressing Hidden Hunger With Agronomy Randomized Controlled Trial

2022 ◽  
Vol 8 ◽  
Author(s):  
Edward J. M. Joy ◽  
Alexander A. Kalimbira ◽  
Joanna Sturgess ◽  
Leonard Banda ◽  
Gabriella Chiutsi-Phiri ◽  
...  
Keyword(s):  
Rural Community ◽  
Controlled Trial ◽  
Selenium Deficiency ◽  
Selenium Concentration ◽  
Serum Selenium ◽  
Selenium Status ◽  
Maize Flour ◽  
Hidden Hunger ◽  
Serum Selenium Concentration ◽  
Women And Children

Background: Selenium deficiency is widespread in the Malawi population. The selenium concentration in maize, the staple food crop of Malawi, can be increased by applying selenium-enriched fertilizers. It is unknown whether this strategy, called agronomic biofortification, is effective at alleviating selenium deficiency.Objectives: The aim of the Addressing Hidden Hunger with Agronomy (AHHA) trial was to determine whether consumption of maize flour, agronomically-biofortified with selenium, affected the serum selenium concentrations of women, and children in a rural community setting.Design: An individually-randomized, double-blind placebo-controlled trial was conducted in rural Malawi. Participants were randomly allocated in a 1:1 ratio to receive either intervention maize flour biofortified with selenium through application of selenium fertilizer, or control maize flour not biofortified with selenium. Participant households received enough flour to meet the typical consumption of all household members (330 g capita−1 day−1) for a period of 8 weeks. Baseline and endline serum selenium concentration (the primary outcome) was measured by inductively coupled plasma mass spectrometry (ICP-MS).Results: One woman of reproductive age (WRA) and one school-aged child (SAC) from each of 180 households were recruited and households were randomized to each group. The baseline demographic and socioeconomic status of participants were well-balanced between arms. No serious adverse events were reported. In the intervention arm, mean (standard deviation) serum selenium concentration increased over the intervention period from 57.6 (17.0) μg L−1 (n = 88) to 107.9 (16.4) μg L−1 (n = 88) among WRA and from 46.4 (14.8) μg L−1 (n = 86) to 97.1 (16.0) μg L−1 (n = 88) among SAC. There was no evidence of change in serum selenium concentration in the control groups.Conclusion: Consumption of maize flour biofortified through application of selenium-enriched fertilizer increased selenium status in this community providing strong proof of principle that agronomic biofortification could be an effective approach to address selenium deficiency in Malawi and similar settings.Clinical Trial Registration:http://www.isrctn.com/ISRCTN85899451, identifier: ISRCTN85899451.

scholarly journals The association between serum selenium concentration and prognosis in patients with heart failure in a Chinese population

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Zhiliang Zhang ◽  
Chao Chang ◽  
Yuxin Zhang ◽  
Zhiyong Chai ◽  
Jinbei Li ◽  
...  
Keyword(s):  
Heart Failure ◽  
Chinese Population ◽  
Selenium Concentration ◽  
Chinese Patients ◽  
Serum Selenium ◽  
Increased Risk ◽  
Patients With Heart Failure ◽  
All Cause Mortality ◽  
Serum Selenium Concentration ◽  
Baseline Information

AbstractWhether Selenium (Se) deficiency relates with adverse prognosis in Chinese patients with heart failure (HF) is still unknown. This study aimed to investigate the association of serum Se level and the outcomes of patients with HF in a Chinese population. Patients with HF and serum Se examination were retrospectively included. Baseline information were collected at patient’s first admission. The primary and secondary outcomes were all-cause mortality and rehospitalization for HF during follow-up, respectively. The study participants were divided into quartiles according to their serum Se concentrations. The Cox proportional hazard models were adopted to estimate the association of serum Se levels with observed outcomes. A total of 411 patients with HF with a mean age of 62.5 years were included. The mean serum level of Se was 68.3 ± 27.7 µg/L. There was nonsignificant difference of baseline characterizes between the four quartile groups. In comparison with patients in the highest quartile, those with the lowest quartile (17.40–44.35 µg/L) were associated with increased risk of all-cause mortality [adjusted hazard ratios (95% CI) 2.32 (1.43–3.77); Ptrend = 0.001]. Our study suggested that a lower serum Se level was significantly associated with increased risk of all-cause mortality in patients with HF.

Low serum selenium concentration in patients with colonic adenomatous polyps

1993 ◽  
Vol 12 ◽  
pp. 46
Author(s):  
F. Fernández-Bañares ◽  
M. Esteve ◽  
M.D. Mingorance ◽  
A. Abad-Lacruz ◽  
E. Cabré ◽  
...  
Keyword(s):  
Selenium Concentration ◽  
Adenomatous Polyps ◽  
Serum Selenium ◽  
Serum Selenium Concentration ◽  
Low Serum

scholarly journals Serum selenium concentration is associated with metabolic factors in the elderly: a cross-sectional study

2010 ◽  
Vol 7 (1) ◽  
pp. 38 ◽  
Author(s):  
Kuen-Cheh Yang ◽  
Long-Teng Lee ◽  
Yow-Shan Lee ◽  
Hui-Ying Huang ◽  
Ching-Yu Chen ◽  
...  
Keyword(s):  
Selenium Concentration ◽  
The Elderly ◽  
Cross Sectional Study ◽  
Serum Selenium ◽  
Sectional Study ◽  
Metabolic Factors ◽  
Cross Sectional ◽  
Serum Selenium Concentration

scholarly journals The Evaluation of Serum Selenium Concentration in Children with Febrile Convulsion

2016 ◽  
Vol 24 (4) ◽  
pp. 95-103
Author(s):  
Nooshin Taghizadegan ◽  
Sima Afsharnezhad ◽  
Hossein Abbaspour ◽  
◽  
◽  
...  
Keyword(s):  
Selenium Concentration ◽  
Febrile Convulsion ◽  
Serum Selenium ◽  
Serum Selenium Concentration

scholarly journals Injectable organic and inorganic selenium in dairy cows – Effects on milk, blood and somatic cell count levels

2019 ◽  
Vol 86 (1) ◽  
Author(s):  
Gert M. Ferreira ◽  
Inge-Marie Petzer
Keyword(s):  
Dairy Cows ◽  
Somatic Cell ◽  
Cell Count ◽  
Negative Correlation ◽  
Somatic Cell Count ◽  
Selenium Concentration ◽  
Trace Minerals ◽  
Serum Selenium ◽  
Inorganic Selenium ◽  
Serum Selenium Concentration

Mastitis is the most costly disease of dairy cows. A pro-active approach includes insuring adequate levels of selective trace minerals. The aim of this study was to determine the effect of two different commercially available, injectable selenium products, (sodium) Na-selenite (inorganic) and (selenium) Se-methionine (organic), on milk composition and on serum and milk selenium concentrations in high-yielding Holstein cows on total mix ration. Sixty multiparous cows were randomly selected into three groups of 20, one control group and two groups supplemented with injectable trace minerals. Blood and milk samples were collected over a period of 60 days. No specific change was indicated in milk yield, lactose, milk urea nitrogen (MUN) and milk pH levels compared with baseline values. The Se-methionine supplemented group showed a numerical increase in total milk protein percentage. In the group injected with Se-methionine, a negative correlation was present for the initial 72 hours between serum selenium concentration and somatic cell count (SCC) and a highly significant (p 0.001) increase in milk selenium concentration for the initial 24 hours. Serum selenium concentration of Se-methionine-supplemented cows was however not significantly changed. Injection of Na-selenite led to a 60-day initial increase in serum selenium concentration above baseline levels and a significant milk selenium concentration on day 1 but to a negative correlation between serum selenium concentration and SCC. Differences in serum and milk selenium concentrations followed with the use of organic and inorganic selenium injectables. Injectable Na-selenite, as selenium, can be of important value for cattle farmers if supplemented on strategically physiological periods to improve production, reproduction and immunity.

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