scholarly journals EEG FEATURES AT DIFFERENT LEVELS OF WAKEFULNESS IN HEALTHY CHILDREN AND CHILDREN WITH INFANTILE AUTISM (IA)

2020 ◽  
Author(s):  
Varteres Khatlamadzhiyan ◽  
Yuliya Kharkova ◽  
Lyudmila Ivanitskaya
Keyword(s):  
Infantile Autism ◽  
Healthy Children ◽  
Different Levels ◽  
Eeg Features

Sticks and Stones May Break My Bones . . . Reasoning About Illness Causality and Body Functioning in Children Who Have a Chronic Illness

PEDIATRICS ◽  
1991 ◽  
Vol 88 (3) ◽  
pp. 608-619
Author(s):  
Ellen C. Perrin ◽  
Aline G. Sayer ◽  
John B. Willett
Keyword(s):  
Chronic Illness ◽  
Age Differences ◽  
Conceptual Development ◽  
Seizure Disorder ◽  
Healthy Children ◽  
Cognitive Reasoning ◽  
Different Types ◽  
Reasoning Skills ◽  
Experience Of Illness ◽  
Different Levels

Children's concepts about illness causality and bodily functioning change in a predictable way with advancing age. Differences in the understanding of these concepts in healthy children vs children with a chronic illness have not been clearly delineated. This study included 49 children with a seizure disorder, 47 children with an orthopaedic condition, and 96 healthy children, all with normal intelligence and ranging in age from 5 to 16 years. It demonstrates systematic differences in children's general reasoning skills and in their understanding of concepts about illness causality and bodily functioning, as a function of their age and experience of illness. At all ages, children who had a condition with orthopaedic involvement reported less sophisticated general reasoning and concepts about illness than did healthy children; children with a seizure disorder reported similar general reasoning skills to those of healthy children, but considerably less sophisticated concepts about illness. children's concepts about body functioning did not differ as a function of the presence of a chronic illness. When their different levels of general cognitive reasoning were statistically controlled, children with a chronic illness had somewhat more sophisticated concepts about bodily functioning than did healthy children. Differences in conceptual development among children with different types of illnesses lead to interesting speculations with regard to the effects of particular illness characteristics on children's cognitive development.

P.7.a.009 Different levels of salivary steroids in autistic and healthy children

2010 ◽  
Vol 20 ◽  
pp. S615-S616
Author(s):  
M.D. Majewska ◽  
M. Hill ◽  
E. Urbanowicz ◽  
P. Rok-Bojko ◽  
I. Namyslowska ◽  
...  
Keyword(s):  
Healthy Children ◽  
Different Levels

scholarly journals The maternal effect in infantile autism: elevated DNA damage degree in patients and their mothers

2016 ◽  
Vol 62 (4) ◽  
pp. 466-470 ◽  
Author(s):  
L.N. Porokhovnik ◽  
S.V. Kostyuk ◽  
E.S. Ershova ◽  
S.M. Stukalov ◽  
N.N. Veiko ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Dna Damage ◽  
Maternal Effect ◽  
Infantile Autism ◽  
Reproductive Age ◽  
Control Group ◽  
Healthy Children ◽  
Tail Moment ◽  
Autistic Children ◽  
Comet Tail

Infantile autism is a common disorder of mental development, which is characterized by impairments in the communicative, cognitive and speech spheres and obsessional stereotyped behaviour. Although in most cases, pathogenic factors remain unclear, infantile autism has a significant hereditary component, however, its etiology is also under the influence of environmental factors, including the condition of the mother's body during pregnancy (“maternal effect”). Oxidative stress is assumed to play a key role in the pathogenesis of infantile autism. It is known that oxidative stress has a prominent genotoxic effect, which is realized through inducing single and double strand breaks of the nuclear DNA. We evaluated the degree of DNA damage in patients with infantile autism and their mothers using DNA comet assay. The comet tail moment and DNA per cent ratio in the tail were assessed for each individual. The two parameters appeared to be strongly correlated (r=0.90). Mean and median values of both parameters were considerably higher in the sample of autistic children, than in age-matching healthy controls. Interestingly, these parameters were also elevated in healthy mothers of autistic children, with no difference from the values in the group of autistic children. The control group of healthy women of reproductive age, who had no children with autism, differed by the DNA comet tail moment from the group of mothers of autistic children, but did not differ significantly from the control group of healthy children. The results suggest that there are genotoxic factors in mentally healthy mothers of autistic children, which can determine the pathological process in the foeti via environmental “maternal effect” during gestation.

scholarly journals Comparison of different levels of positive expiratory pressure on chest wall volumes in healthy children and patients with fibrosis

2017 ◽  
Vol 24 (3) ◽  
pp. 311-320 ◽  
Author(s):  
Silvia Angélica Brilhante ◽  
Rêcio Bento Florêncio ◽  
Lucien Peroni Gualdi ◽  
Vanessa Regiane Resqueti ◽  
Andrea Aliverti ◽  
...  
Keyword(s):  
Lung Function ◽  
Chest Wall ◽  
Minute Ventilation ◽  
Control Group ◽  
Healthy Children ◽  
Acute Effects ◽  
Optoelectronic Plethysmography ◽  
Induced Changes ◽  
Different Levels ◽  
Positive Expiratory Pressure

ABSTRACT Positive Expiratory Pressure (PEP) improves lung function, however, PEP-induced changes are not fully established. The aim of this study was to assess the acute effects of different PEP levels on chest wall volumes and the breathing pattern in children with Cystic Fibrosis (CF). Anthropometric data, lung function values, and respiratory muscle strength were collected. Chest wall volumes were assessed by Optoelectronic plethysmography at rest and during the use of different PEP levels (10 and 20 cm H2O), randomly chosen. Eight subjects with CF (5M, 11.5±3.2 years, 32±9.5 kilograms) and seven control subjects (4M, 10.7±1.5 years, 38.2±7.8 kilograms) were recruited. The CF group showed significantly lower FEF values 25-75% (CF: 1.8±0.8 vs. CG: 2.3±0.6) and FEV1/FVC ratio (CF: 0.8±0.1 vs. CG: 1±0.1) compared with the control group (p<0.05). Different PEP levels increased the usual volume in chest wall and its compartments in both groups; however, this volume was significantly higher in the control group compared with the CF group during PEP20 (CW: 0.77±0.25 L vs. 0.44±0.16 L; RCp: 0.3±0.13 L vs. 0.18±0.1 L; RCa: 0.21±0.1 L vs. 0.12±0.1 L; AB: 0.25±0.1 L vs. 0.15±0.1 L; p<0.05 for all variables). Minute ventilation was significantly higher during PEP compared with breathing at rest in both groups (p<0.005). End-expiratory volume was also higher during PEP compared with breathing at rest for chest wall and pulmonary rib cage in both groups (p<0.05). Different PEP levels may increase chest wall volumes in CF patients.

scholarly journals THE BALANCE OF IL-1Β, IL-10 AND THE LEVEL OF IKBΑ EXPRESSION IN CHILDREN WITH CHRONIC CATARRHAL GINGIVITIS AND GASTRODUODENITIS

2021 ◽  
Vol 74 (1) ◽  
pp. 90-93
Author(s):  
Olga V. Sheshukova ◽  
Sofiya S. Bauman ◽  
David S. Avetikov ◽  
Stanislav O. Stavitskiy
Keyword(s):  
Oral Fluid ◽  
Cytokine Production ◽  
Primary School Children ◽  
Healthy Children ◽  
Health It ◽  
Anti Inflammatory ◽  
Somatic Diseases ◽  
Different Levels ◽  
Group 1

The aim: To define the level of pro- and anti-inflammatory IL-1β, IL-10 in the oral fluid of children with chronic gastroduodenitis, depending on the level of IkBα expression. Materials and methods: Studiing the oral fluid and scraping of the gums of 50 children 6-12 years old was carried out to determine the level of IL-1β, IL-10 and IkBα. The children were divided into 3 groups. Group 1 - 10 children with healthy periodontium and without somatic diseases. 2nd group - 20 somatically healthy children with chronic catarrhal gingivitis. The third group (20 children) of children with gastroduodenitis and chronic catarrhal gingivitis. The determination of the mRNA expression of the IkBα geneand the level of IL-10 and IL-1β in the oral fluid was carried out by real-time PCR. Results: We determined that the level of pro-inflammatory IL-1β in the oral fluid of primary school children had different levels in accordance with the state of dental and somatic health. It was the lowest in somatically healthy children without signs of gingivitis. We revealed that the level of IL-10 has anti-inflammatory properties, and an inverse relationship with the concentration of IL-1β in the oral fluid of examined children. Analysis of IkBα expression made it possible to reveal its suppression in children of the second and third groups compared with healthy children. Conclusions: We found changes in the levels of IkBα in the gums of children with chronic catarrhal gingivitis; attenuated IkBα expression may lead to the deregulation of NF-κB pathways in the pathogenesis of periodontitis. Decreased IkBα expression may affect cytokine production and inflammatory response associated with chronic catarrhal gingivitis and with chronic gastroduodenitis.

Dependence of Intergranular Fracture on Boundary Topography and Cohesion

1973 ◽  
Vol 31 ◽  
pp. 150-151
Author(s):  
J. E. Doherty ◽  
A. F. Giamei ◽  
B. H. Kear ◽  
C. W. Steinke
Keyword(s):  
Grain Boundary ◽  
Room Temperature ◽  
Nickel Base Superalloy ◽  
Boundary Shear ◽  
Room Temperature Ductility ◽  
Solid Solution Matrix ◽  
Nickel Base ◽  
Solution Matrix ◽  
Different Levels ◽  
Base Superalloy

Recently we have been investigating a class of nickel-base superalloys which possess substantial room temperature ductility. This improvement in ductility is directly related to improvements in grain boundary strength due to increased boundary cohesion through control of detrimental impurities and improved boundary shear strength by controlled grain boundary micros true tures.For these investigations an experimental nickel-base superalloy was doped with different levels of sulphur impurity. The micros tructure after a heat treatment of 1360°C for 2 hr, 1200°C for 16 hr consists of coherent precipitates of γ’ Ni3(Al,X) in a nickel solid solution matrix.

Immunoenzymatic demonstration of the simultaneous presence of transferrin, hemopexin and albumin in a same hepatocyte and their ultrastructural localization

1978 ◽  
Vol 36 (2) ◽  
pp. 88-89
Author(s):  
M. Kraemer ◽  
J. Foucrier ◽  
J. Vassy ◽  
M.T. Chalumeau
Keyword(s):  
Plasma Proteins ◽  
Rat Hepatocytes ◽  
Ultrastructural Localization ◽  
Carrier Proteins ◽  
Normal Cells ◽  
Adult Rat ◽  
Adult Rat Hepatocytes ◽  
Monospecific Antisera ◽  
Different Levels

Some authors using immunofluorescent techniques had already suggested that some hepatocytes are able to synthetize several plasma proteins. In vitro studies on normal cells or on cells issued of murine hepatomas raise the same conclusion. These works could be indications of an hepatocyte functionnal non-specialization, meanwhile the authors never give direct topographic proofs suitable with this hypothesis.The use of immunoenzymatic techniques after obtention of monospecific antisera had seemed to us useful to bring forward a better knowledge of this problem. We have studied three carrier proteins (transferrin = Tf, hemopexin = Hx, albumin = Alb) operating at different levels in iron metabolism by demonstrating and localizing the adult rat hepatocytes involved in their synthesis.Immunological, histological and ultrastructural methods have been described in a previous work.

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