scholarly journals SOME CURIOUS FINDINGS HAIR FOLLICLES BIOELECTROMAGNETIC RADIATION EXPRESSED AS LIGHT DISPLACING MATTER IN ITS PATH AND THE CONTRALATERAL EMISSION OF MAGNETIC FIELDS FOUND IN THE HAIR SHAFT

2021 ◽  
Vol 9 (7) ◽  
pp. 334-342
Author(s):  
Abraham A. Embi
Keyword(s):  
Magnetic Fields ◽  
Electromagnetic Radiation ◽  
Biological Tissue ◽  
Light Flash ◽  
Incidental Finding ◽  
Hair Shaft ◽  
Hair Follicles ◽  
Primary Factor ◽  
Light Rays

BACKGROUND In physics the term light refers to electromagnetic radiation, which includes visible light, which has also been described as exerting physical pressure on matter in its path; this could be explained by the “particle nature of light”. To date light rays emission experiments has been done mainly on non-living matter. This manuscript will show in vitro results where biological tissue (hair follicles) is shown emitting electromagnetic radiation in a light form and displacing particles in its path. Additionally the hair shaft one-sided biomagnetism is shown. METHODS A mini-review of prior experiments by this author and others are herein presented where bioelectromagnetic fields expressed as light are shown displacing matter of ferric cyanide chemical compounds. A seminal paper published in 1980, is also included where human hair follicles had been documented as emitting magnetic fields when applying pressure on the human scalp. RESULTS Findings are presented where light rays or flashes emitted by hair follicles are documented to exert pressure in matter in its path causing displacement; and in one case a flash of light seen as a primary factor in totally reversing turmoil caused by a piezoelectric or pressure induced maneuver. As an incidental finding: The hair shaft is also found to express one-sided magnetic fields similar to inanimate magnets inhibiting human blood issue fibrin formation (clot formation). CONCLUSIONS Presented is a mini-review of biological tissue previously found to emit magnetic fields, now also expressed as light. The light is displayed shown as a “flash” or a “stream”, in both instances displacing matter in its path. The light flash also appears to be a primary factor in bringing equilibrium into the piezoelectric disturbed bioelectromagnetic field. Question arise: What is/are the biological/molecular consequences of living tissue under stress emitting light energy? Why is the hair shaft bioelectromamagnetic field shown in a contralateral fashion, this when the hair follicle is not? Further research is recommended.

scholarly journals Integrin-linked kinase is required for epidermal and hair follicle morphogenesis

2007 ◽  
Vol 177 (3) ◽  
pp. 501-513 ◽  
Author(s):  
Katrin Lorenz ◽  
Carsten Grashoff ◽  
Robert Torka ◽  
Takao Sakai ◽  
Lutz Langbein ◽  
...  
Keyword(s):  
Hair Follicle ◽  
Leading Edge ◽  
Hair Shaft ◽  
Hair Follicles ◽  
Membrane Dynamics ◽  
Epidermal Keratinocytes ◽  
Outer Root Sheath ◽  
Root Sheath ◽  
Integrin Linked Kinase

Integrin-linked kinase (ILK) links integrins to the actin cytoskeleton and is believed to phosphorylate several target proteins. We report that a keratinocyte-restricted deletion of the ILK gene leads to epidermal defects and hair loss. ILK-deficient epidermal keratinocytes exhibited a pronounced integrin-mediated adhesion defect leading to epidermal detachment and blister formation, disruption of the epidermal–dermal basement membrane, and the translocation of proliferating, integrin-expressing keratinocytes to suprabasal epidermal cell layers. The mutant hair follicles were capable of producing hair shaft and inner root sheath cells and contained stem cells and generated proliferating progenitor cells, which were impaired in their downward migration and hence accumulated in the outer root sheath and failed to replenish the hair matrix. In vitro studies with primary ILK-deficient keratinocytes attributed the migration defect to a reduced migration velocity and an impaired stabilization of the leading-edge lamellipodia, which compromised directional and persistent migration. We conclude that ILK plays important roles for epidermis and hair follicle morphogenesis by modulating integrin-mediated adhesion, actin reorganization, and plasma membrane dynamics in keratinocytes.

scholarly journals Wnt10b promotes hair follicles growth and dermal papilla cells proliferation via Wnt/β-Catenin signaling pathway in Rex rabbits

2020 ◽  
Vol 40 (2) ◽  
Author(s):  
Zhenyu Wu ◽  
Yanli Zhu ◽  
Hongli Liu ◽  
Gongyan Liu ◽  
Fuchang Li
Keyword(s):  
Cell Cycle ◽  
Signaling Pathway ◽  
Cell Cycle Progression ◽  
Dermal Papilla ◽  
Hair Shaft ◽  
Hair Follicles ◽  
Dermal Papilla Cells ◽  
Root Sheath ◽  
Inner Root Sheath

Abstract Wnt signaling plays an important role in the growth and development of hair follicles (HFs). Among the signaling molecules, Wnt10b was shown to promote the differentiation of primary skin epithelial cells toward the hair shaft and inner root sheath of the HF cells in mice in vitro. Whisker HFs were isolated from Rex rabbits and cultured in vitro to measure hair shaft growth. Meanwhile, dermal papilla cells (DPCs) were isolated and cultured in vitro. Treatment with AdWnt10b or the Wnt/β-Catenin Pathway inhibitor, XAV939, assessed the DPCs proliferation by CCK-8 assay. And the cell cycle was also analyzed by flow cytometry. We found that Wnt10b could promote elongation of the hair shaft, whereas XAV-939 treatment could eliminated this phenomenon. AdWnt10b treatment promoted the proliferation and induced G1/S transition of DPCs. AdWnt10b stimulation up-regulated β-Catenin protein in DPCs. Inhibition of Wnt/β-Catenin signaling by XAV-939 could decreased the basal and Wnt10b-enhanced proliferation of DPCs. And could also suppress the cell cycle progression in DPCs. In summary, our study demonstrates that Wnt10b could promote HFs growth and proliferation of DPCs via the Wnt/β-Catenin signaling pathway in Rex rabbits.

Human hair growth in vitro

1990 ◽  
Vol 97 (3) ◽  
pp. 463-471
Author(s):  
M.P. Philpott ◽  
M.R. Green ◽  
T. Kealey
Keyword(s):  
Hair Follicle ◽  
Human Hair ◽  
Subcutaneous Fat ◽  
Hair Shaft ◽  
Hair Follicles ◽  
Anagen Hair ◽  
Scalpel Blade ◽  
Thymidine Autoradiography

We report for the first time the successful maintenance and growth of human hair follicles in vitro. Human anagen hair follicles were isolated by microdissection from human scalp skin. Isolation of the hair follicles was achieved by cutting the follicle at the dermo-subcutaneous fat interface using a scalpel blade. Intact hair follicles were then removed from the fat using watchmakers' forceps. Isolated hair follicles maintained free-floating in supplemented Williams E medium in individual wells of 24-well multiwell plates showed a significant increase in length over 4 days. The increase in length was seen to be attributed to the production of a keratinised hair shaft, and was not associated with the loss of hair follicle morphology. [methyl-3H]thymidine autoradiography confirmed that in vitro the in vivo pattern of DNA synthesis was maintained; furthermore, [35S]methionine labelling of keratins showed that their patterns of synthesis did not change with maintenance. The importance of this model to hair follicle biology is further demonstrated by the observations that TGF-beta 1 has a negative growth-regulatory effect on hair follicles in vitro and that EGF mimics the in vivo depilatory effects that have been reported in sheep and mice.

scholarly journals CD133-positive dermal papilla-derived Wnt ligands regulate postnatal hair growth

2016 ◽  
Vol 473 (19) ◽  
pp. 3291-3305 ◽  
Author(s):  
Linli Zhou ◽  
Kun Yang ◽  
April Carpenter ◽  
Richard A. Lang ◽  
Thomas Andl ◽  
...  
Keyword(s):  
Hair Follicle ◽  
Hair Growth ◽  
Dermal Papilla ◽  
Hair Shaft ◽  
Hair Follicles ◽  
Proliferation And Differentiation ◽  
Wnt Ligands ◽  
Epithelial Compartment ◽  
Hair Follicle Growth

Active Wnt/β-catenin signaling in the dermal papilla (DP) is required for postnatal hair cycling. In addition, maintenance of the hair-inducing ability of DP cells in vitro requires external addition of Wnt molecules. However, whether DP cells are a critical source of Wnt ligands and induce both autocrine and paracrine signaling cascades to promote adult hair follicle growth and regeneration remains elusive. To address this question, we generated an animal model that allows inducible ablation of Wntless (Wls), a transmembrane Wnt exporter protein, in CD133-positive (CD133+) DP cells. CD133+ cells have been shown to be a specific subpopulation of cells in the DP, which possesses the hair-inducing capability. Here, we show that ablation of Wls expression in CD133+ DP cells results in a shortened period of postnatal hair growth. Mutant hair follicles were unable to enter full anagen (hair growth stage) and progressed toward a rapid regression. Notably, reduced size of the DP and decreased expression of anagen DP marker, versican, were observed in hair follicles when CD133+ DP cells lost Wls expression. Further analysis showed that Wls-deficient CD133+ DP cells led to reduced proliferation and differentiation in matrix keratinocytes and melanocytes that are needed for the generation of the hair follicle structure and a pigmented hair shaft. These findings clearly demonstrate that Wnt ligands produced by CD133+ DP cells play an important role in postnatal hair growth by maintaining the inductivity of DP cells and mediating the signaling cross-talk between the mesenchyme and the epithelial compartment.

scholarly journals INTRODUCING THEORY LINKING GENESIS OF HAIR SHAFT BIPOLARITY WITH ARRECTOR PILI MUSCLE PROXIMAL ATTACHMENT

2021 ◽  
Vol 9 (11) ◽  
pp. 43-47
Author(s):  
Abraham A. Embi
Keyword(s):  
Electromagnetic Radiation ◽  
Human Hair ◽  
Additional Data ◽  
Positive Charge ◽  
Hair Shaft ◽  
Potassium Ferricyanide ◽  
In Vitro Experiments ◽  
Arrector Pili Muscle ◽  
Total Absence

Previous publications described the presence of bipolarity or (+−) electrical charges in the human hair shaft, this due to an apparent segmental electromagnetic radiation Gap demonstrated by a total absence of precipitated Potassium Ferricyanide crystals. In this manuscript additional data is presented elucidating the genesis of said absence. The in vitro experiments showing a correlation between a segmental absence of longitudinal terminal palisades nervous endings prevalent in the rest of the outer membrane in the hair follicle anatomy. Due to their intrinsic metabolism, nerve cells do emit electromagnetic radiation; their absence not allowing for the positive (+) charge of zero precipitated Potassium Ferricyanide crystals to reach one side of the shaft. In addition it was concluded that there are two types of human hair images. The first by optical microscopy, the second a functional one obtained from electromagnetic radiation precipitating Ferricyanide crystals.

A box coil for the stimulation of biological tissue and cells in vitro and in vivo by pulsed magnetic fields

2000 ◽  
Vol 47 (3) ◽  
pp. 402-408 ◽  
Author(s):  
J.H. Battocletti ◽  
M.Y. Macias ◽  
F.A. Pintar ◽  
D.J. Maiman ◽  
C.H. Sutton
Keyword(s):  
Magnetic Fields ◽  
Biological Tissue ◽  
Pulsed Magnetic Fields ◽  
Stimulation Of

The detection of apoptosis and bcl2 in isolated secondary mohair follicles (growing and quiescent), cultured in vitro in the presence or absence of biotin

1999 ◽  
Vol 1999 ◽  
pp. 159-159
Author(s):  
A.M. Tahmasbi ◽  
H. Galbraith ◽  
J.R. Scaife ◽  
D. Finn
Keyword(s):  
Hair Growth ◽  
Hair Shaft ◽  
Hair Follicles ◽  
Epidermal Cells ◽  
Thymidine Uptake ◽  
Active Process ◽  
Biotin Deficiency ◽  
Proliferation And Differentiation ◽  
Apoptosis Inhibitor

Apoptosis is a physiologically active process whereby cells die in a programmed manner (Stenn et al 1993). Growth of hair occurs as a consequence of proliferation and differentiation of the epidermal cells in the bulb of the hair follicles. Reduction of hair growth or loss of follicle viability may arise from reduction in proliferation, and also from apoptosis of epidermal hair shaft-forming cells. Increases in apoptosis have been associated with reduction in expression of the apoptosis inhibitor bcl2 (Lindner et al 1997). Previous studies (Tahmasbi et al 1998) have shown that biotin deficiency reduced the viability of mohair follicles and thymidine uptake in vitro. The aim of this work was to investigate the presence of apoptosis and bcl2 in follicles which maintained growth or were quiescent following culture in media unsupplemented or supplemented with biotin.

THE DRUNKEN HAIR: INTRODUCING IN VIVO DEMONSTRATION OF INCREASED BLOOD ALCOHOL CONCENTRATION TEMPORARY DISRUPTING HUMAN HAIR FOLLICLES EMISSION OF ELECTROMAGNETIC RADIATION

2020 ◽  
Vol 8 (10) ◽  
pp. 123-130
Author(s):  
Abraham A. Embi
Keyword(s):  
Electromagnetic Radiation ◽  
Hair Follicle ◽  
Human Hair ◽  
Blood Alcohol Concentration ◽  
Physical Symptoms ◽  
Alcohol Concentration ◽  
Hair Follicles ◽  
Blood Alcohol

The human hair consists of a follicle a.k.a root penetrating the skin and an outer skin structure commonly called the shaft. The hair follicle has been classified as a miniorgan having its own cells divisions; aging stages and also demonstrated to be an energy emitter in the form of electromagnetic radiation. The intent of this manuscript is to introduce documentation from in vivo experiments showing the deleterious effect of alcohol consumption on the previously documented hair follicle intrinsic and orderly emission of energy a.k.a. Electromagnetic Radiation (EMR). This was possible by a minor modification of a tabletop optical microscopy technique introduced in 2015 and designed to display plant and animals tissue EMR. In vitro control experiments had shown that a drop of white wine covering a human hair follicle placed on a glass slide caused what appeared to be a disruption on the hair follicle EMR emissions; the addition of chemicals to the wine during manufacturing could have caused that effect. The answer could lie in an in vivo alcohol drinking approach by increasing only the blood alcohol concentration (BAC). In this manuscript two in vitro and two in vivo are presented where the author, a non-alcohol drinker, purposely and during fasting underwent two binge-drinking episodes aimed to increase his BAC and investigate its impact on hair follicles. Several black beard hair samples were plucked via tweezers as controls; additional samples were also plucked and processed at approximately peak alcohol physical symptoms such cheek numbness and dizziness which occurred between 35 and 45 minutes post two episodes of wine or wine and beer binges. Images and video-recordings are presented.

Sign in / Sign up

Export Citation Format

Share Document